| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chantal Martin-Soelc. Is depression associated with dysfunction of the central reward system? Biochemical Society transactions. vol 37. issue Pt 1. 2009-02-11. PMID:19143654. |
because the mesocorticolimbic dopamine system is involved in reward processing, it has been hypothesized that a reduced function of this system could underlie the anhedonia and amotivation associated with depression. |
2009-02-11 |
2023-08-12 |
human |
| Chantal Martin-Soelc. Is depression associated with dysfunction of the central reward system? Biochemical Society transactions. vol 37. issue Pt 1. 2009-02-11. PMID:19143654. |
in conclusion, there is evidence for a dysfunction of the dopamine system in depression and for blunted response to reward signals. |
2009-02-11 |
2023-08-12 |
human |
| Katharina Domschke, Udo Dannlowski, Patricia Ohrmann, Bruce Lawford, Jochen Bauer, Harald Kugel, Walter Heindel, Ross Young, Phillip Morris, Volker Arolt, Jürgen Deckert, Thomas Suslow, Bernhard T Baun. Cannabinoid receptor 1 (CNR1) gene: impact on antidepressant treatment response and emotion processing in major depression. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 10. 2009-01-26. PMID:18579347. |
this analysis provides preliminary support for a role of cnr1 gene variation in depression and anxiety, potentially mediated by subcortical hypo-responsiveness to social reward stimuli. |
2009-01-26 |
2023-08-12 |
human |
| Kim A Wright, Dominic Lam, Richard G Brow. Dysregulation of the behavioral activation system in remitted bipolar I disorder. Journal of abnormal psychology. vol 117. issue 4. 2009-01-13. PMID:19025230. |
however, examination of the relation between number of previous episodes and time to recover revealed that history of mania was associated with prolonged activation following reward, whereas history of both mania and depression were associated with prolonged recovery following frustration. |
2009-01-13 |
2023-08-12 |
Not clear |
| Diego A Pizzagalli, Dan Iosifescu, Lindsay A Hallett, Kyle G Ratner, Maurizio Fav. Reduced hedonic capacity in major depressive disorder: evidence from a probabilistic reward task. Journal of psychiatric research. vol 43. issue 1. 2009-01-12. PMID:18433774. |
the goal of the present study was to test the hypothesis that individuals with major depression are characterized by blunted reward responsiveness, particularly when anhedonic symptoms are prominent. |
2009-01-12 |
2023-08-12 |
Not clear |
| Andreas Lindqvist, Annemie Baelemans, Charlotte Erlanson-Albertsso. Effects of sucrose, glucose and fructose on peripheral and central appetite signals. Regulatory peptides. vol 150. issue 1-3. 2008-11-14. PMID:18627777. |
in conclusion, consumption of glucose, sucrose or fructose solution results in caloric overconsumption and body weight gain through activation of hunger signals and depression of satiety signals as well as activation of reward components. |
2008-11-14 |
2023-08-12 |
rat |
| Taiki Takahashi, Hidemi Oono, Takeshi Inoue, Shuken Boku, Yuki Kako, Yuji Kitaichi, Ichiro Kusumi, Takuya Masui, Shidn Nakagawa, Katsuji Suzuki, Teruaki Tanaka, Tsukasa Koyama, Mark H B Radfor. Depressive patients are more impulsive and inconsistent in intertemporal choice behavior for monetary gain and loss than healthy subjects--an analysis based on Tsallis' statistics. Neuro endocrinology letters. vol 29. issue 3. 2008-09-08. PMID:18580849. |
depression has been associated with impaired neural processing of reward and punishment. |
2008-09-08 |
2023-08-12 |
human |
| Gabriele Hampp, Jürgen A Ripperger, Thijs Houben, Isabelle Schmutz, Christian Blex, Stéphanie Perreau-Lenz, Irene Brunk, Rainer Spanagel, Gudrun Ahnert-Hilger, Johanna H Meijer, Urs Albrech. Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Current biology : CB. vol 18. issue 9. 2008-08-04. PMID:18439826. |
the circadian clock has been implicated in addiction and several forms of depression [1, 2], indicating interactions between the circadian and the reward systems in the brain [3-5]. |
2008-08-04 |
2023-08-12 |
mouse |
| Adam Ponz. Dynamical model of salience gated working memory, action selection and reinforcement based on basal ganglia and dopamine feedback. Neural networks : the official journal of the International Neural Network Society. vol 21. issue 2-3. 2008-07-10. PMID:18280108. |
auto-catalytic feedback from a dopamine reward signal modulates three-way hebbian long term potentiation and depression at the cortical-striatal synapses which represent the cue-action associations. |
2008-07-10 |
2023-08-12 |
Not clear |
| Yael Lavi-Avnon, Aron Weller, John P M Finberg, Iris Gispan-Herman, Noa Kinor, Yaakov Stern, Mariana Schroeder, Vered Gelber, S Yoav Bergman, David H Overstreet, Gal Yadi. The reward system and maternal behavior in an animal model of depression: a microdialysis study. Psychopharmacology. vol 196. issue 2. 2008-05-19. PMID:17928996. |
the reward system and maternal behavior in an animal model of depression: a microdialysis study. |
2008-05-19 |
2023-08-12 |
rat |
| Anthony S Rauhut, Isaac J Zentner, Stacey K Mardekian, Jason B Tanenbau. Wistar Kyoto and Wistar rats differ in the affective and locomotor effects of nicotine. Physiology & behavior. vol 93. issue 1-2. 2008-04-22. PMID:17889041. |
anhedonia is a characteristic of clinical depression and has been associated with dysfunction of the mesolimbic dopaminergic system, a system also involved in mediating nicotine reward. |
2008-04-22 |
2023-08-12 |
rat |
| Anthony S Rauhut, Isaac J Zentner, Stacey K Mardekian, Jason B Tanenbau. Wistar Kyoto and Wistar rats differ in the affective and locomotor effects of nicotine. Physiology & behavior. vol 93. issue 1-2. 2008-04-22. PMID:17889041. |
to further examine the relationship between anhedonia, clinical depression and nicotine reward, the present experiment determined if wistar kyoto (wky) rats, an animal model of clinical depression, differed from wistar rats in nicotine conditioned place preference (cpp). |
2008-04-22 |
2023-08-12 |
rat |
| Christopher G Davey, Murat Yücel, Nicholas B Alle. The emergence of depression in adolescence: development of the prefrontal cortex and the representation of reward. Neuroscience and biobehavioral reviews. vol 32. issue 1. 2008-02-21. PMID:17570526. |
the emergence of depression in adolescence: development of the prefrontal cortex and the representation of reward. |
2008-02-21 |
2023-08-12 |
Not clear |
| Christopher G Davey, Murat Yücel, Nicholas B Alle. The emergence of depression in adolescence: development of the prefrontal cortex and the representation of reward. Neuroscience and biobehavioral reviews. vol 32. issue 1. 2008-02-21. PMID:17570526. |
we hypothesize that when these distant rewards are frustrated they suppress the reward system, and that when such suppression is extensive and occurs for long enough, the clinical picture that results is one of depression. |
2008-02-21 |
2023-08-12 |
Not clear |
| Thomas E Schlaepfer, Michael X Cohen, Caroline Frick, Markus Kosel, Daniela Brodesser, Nikolai Axmacher, Alexius Young Joe, Martina Kreft, Doris Lenartz, Volker Stur. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17429407. |
deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. |
2008-02-06 |
2023-08-12 |
Not clear |
| Thomas E Schlaepfer, Michael X Cohen, Caroline Frick, Markus Kosel, Daniela Brodesser, Nikolai Axmacher, Alexius Young Joe, Martina Kreft, Doris Lenartz, Volker Stur. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17429407. |
because a prominent clinical feature of depression is anhedonia--the inability to experience pleasure from previously pleasurable activities--and because there is clear evidence of dysfunctions of the reward system in depression, dbs to the nucleus accumbens might offer a new possibility to target depressive symptomatology in otherwise treatment-resistant depression. |
2008-02-06 |
2023-08-12 |
Not clear |
| Thomas E Schlaepfer, Michael X Cohen, Caroline Frick, Markus Kosel, Daniela Brodesser, Nikolai Axmacher, Alexius Young Joe, Martina Kreft, Doris Lenartz, Volker Stur. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 2. 2008-02-06. PMID:17429407. |
dysfunctions of the reward system--in which the nucleus accumbens is a key structure--are implicated in the neurobiology of major depression and might be responsible for impaired reward processing, as evidenced by the symptom of anhedonia. |
2008-02-06 |
2023-08-12 |
Not clear |
| Jennifer S Silk, Ella Vanderbilt-Adriance, Daniel S Shaw, Erika E Forbes, Diana J Whalen, Neal D Ryan, Ronald E Dah. Resilience among children and adolescents at risk for depression: Mediation and moderation across social and neurobiological contexts. Development and psychopathology. vol 19. issue 3. 2008-01-18. PMID:17705905. |
we discuss several factors and their interactions across levels-including genetic factors, stress reactivity, positive affect, neural systems of reward, and sleep-as candidate processes contributing to resilience against depression at the neurobehavioral level. |
2008-01-18 |
2023-08-12 |
Not clear |
| P C Chandler-Laney, E Castaneda, C E Pritchett, M L Smith, M Giddings, A I Artiga, M M Boggian. A history of caloric restriction induces neurochemical and behavioral changes in rats consistent with models of depression. Pharmacology, biochemistry, and behavior. vol 87. issue 1. 2007-08-06. PMID:17490740. |
we investigated the effect of a history of caloric restriction (hcr) in rats that involved cyclic food restriction and refeeding with varying levels of access to palatable food (pf) on: 1) responses to the ssri, fluoxetine; 2) monoamine levels in brain regions central to the control of feeding, reward, and mood regulation; and 3) behavioral tests of anxiety and depression. |
2007-08-06 |
2023-08-12 |
rat |
| Maria E A Armento, Derek R Hopk. The Environmental Reward Observation Scale (EROS): development, validity, and reliability. Behavior therapy. vol 38. issue 2. 2007-07-20. PMID:17499078. |
researchers acknowledge a strong association between the frequency and duration of environmental reward and affective mood states, particularly in relation to the etiology, assessment, and treatment of depression. |
2007-07-20 |
2023-08-12 |
Not clear |