| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Goedecke, X Bengoetxea, P Blaesse, H-C Pape, K Jünglin. µ-opioid receptor-mediated downregulation of midline thalamic pathways to basal and central amygdala. Scientific reports. vol 9. issue 1. 2020-11-04. PMID:31780740. |
brain µ-opioid receptors (mor) mediate reward and help coping with pain, social rejection, anxiety and depression. |
2020-11-04 |
2023-08-13 |
Not clear |
| Brent I Rappaport, Sridhar Kandala, Joan L Luby, Deanna M Barc. Brain Reward System Dysfunction in Adolescence: Current, Cumulative, and Developmental Periods of Depression. The American journal of psychiatry. vol 177. issue 8. 2020-10-07. PMID:32252540. |
brain reward system dysfunction in adolescence: current, cumulative, and developmental periods of depression. |
2020-10-07 |
2023-08-13 |
Not clear |
| Brent I Rappaport, Sridhar Kandala, Joan L Luby, Deanna M Barc. Brain Reward System Dysfunction in Adolescence: Current, Cumulative, and Developmental Periods of Depression. The American journal of psychiatry. vol 177. issue 8. 2020-10-07. PMID:32252540. |
reward system dysfunction is a well-known correlate and predictor of depression in adults and adolescents, with depressed individuals showing blunted (hyporeactive) striatal response to monetary rewards. |
2020-10-07 |
2023-08-13 |
Not clear |
| Brent I Rappaport, Sridhar Kandala, Joan L Luby, Deanna M Barc. Brain Reward System Dysfunction in Adolescence: Current, Cumulative, and Developmental Periods of Depression. The American journal of psychiatry. vol 177. issue 8. 2020-10-07. PMID:32252540. |
the authors examined the relationships between regions of a cortico-striatal circuit supporting reward processing and both current depression and cumulative depression history. |
2020-10-07 |
2023-08-13 |
Not clear |
| Paul J Silvia, Emily C Nusbaum, Kari M Eddington, Roger E Beaty, Thomas R Kwapi. Effort Deficits and Depression: The Influence of Anhedonic Depressive Symptoms on Cardiac Autonomic Activity During a Mental Challenge. Motivation and emotion. vol 38. issue 6. 2020-10-01. PMID:25431505. |
motivational approaches to depression emphasize the role of dysfunctional motivational dynamics, particularly diminished reward and incentive processes associated with anhedonia. |
2020-10-01 |
2023-08-13 |
Not clear |
| Autumn Kujawa, Greg H Proudfit, Rebecca Laptook, Daniel N Klei. Early Parenting Moderates the Association between Parental Depression and Neural Reactivity to Rewards and Losses in Offspring. Clinical psychological science : a journal of the Association for Psychological Science. vol 3. issue 4. 2020-10-01. PMID:26167423. |
children of parents with depression exhibit neural abnormalities in reward processing. |
2020-10-01 |
2023-08-13 |
Not clear |
| Autumn Kujawa, Greg H Proudfit, Rebecca Laptook, Daniel N Klei. Early Parenting Moderates the Association between Parental Depression and Neural Reactivity to Rewards and Losses in Offspring. Clinical psychological science : a journal of the Association for Psychological Science. vol 3. issue 4. 2020-10-01. PMID:26167423. |
we evaluated whether early parenting moderates the effects of parental depression on a neural measure of reward and loss processing in mid-late childhood. |
2020-10-01 |
2023-08-13 |
Not clear |
| Anna Weinberg, Stewart A Shankma. Blunted reward processing in remitted melancholic depression. Clinical psychological science : a journal of the Association for Psychological Science. vol 5. issue 1. 2020-10-01. PMID:28451473. |
blunted reward processing in remitted melancholic depression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Catherine M Cahill, Anna Mw Taylo. Neuroinflammation-a co-occurring phenomenon linking chronic pain and opioid dependence. Current opinion in behavioral sciences. vol 13. 2020-10-01. PMID:28451629. |
opioids are highly effective analgesics because they target both of these elements, by inhibiting pain pathways and alleviating negative affect (including depression) by engaging reward or hedonic pathways. |
2020-10-01 |
2023-08-13 |
Not clear |
| Claire E Manning, Elizabeth S Williams, Alfred J Robiso. Reward Network Immediate Early Gene Expression in Mood Disorders. Frontiers in behavioral neuroscience. vol 11. 2020-10-01. PMID:28503137. |
over the past three decades, it has become clear that aberrant function of the network of interconnected brain regions responsible for reward processing and motivated behavior underlies a variety of mood disorders, including depression and anxiety. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jaime R Silva, Anastassia Vivanco-Carlevari, Claudio Martínez, Mariane Kraus. Introjective Individuals Tend Toward Anhedonia: Self-Report and Experimental Evidence. Frontiers in psychiatry. vol 9. 2020-10-01. PMID:30026709. |
we tested 177 individuals using the beck depression inventory (bdi) subscale for anhedonia and a visual discrimination task with a specific reward system, which was implemented to study reinforcement sensitivity. |
2020-10-01 |
2023-08-13 |
human |
| Tongjian Bai, Meidan Zu, Yang Chen, Wen Xie, Chunlan Cai, Qiang Wei, Gong-Jun Ji, Yanghua Tian, Kai Wan. Decreased Connection Between Reward Systems and Paralimbic Cortex in Depressive Patients. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30038557. |
our results emphasize the role of communication deficits between reward systems and paralimbic cortex in the pathophysiology of depression. |
2020-10-01 |
2023-08-13 |
human |
| Diana Kúkel'ová, Giorgio Bergamini, Hannes Sigrist, Erich Seifritz, Bastian Hengerer, Christopher R Pryc. Chronic Social Stress Leads to Reduced Gustatory Reward Salience and Effort Valuation in Mice. Frontiers in behavioral neuroscience. vol 12. 2020-10-01. PMID:30057529. |
pathology of reward processing is a major clinical feature of stress-related neuropsychiatric disorders including depression. |
2020-10-01 |
2023-08-13 |
mouse |
| Caroline A Browne, Robert Hammack, Irwin Luck. Dysregulation of the Lateral Habenula in Major Depressive Disorder. Frontiers in synaptic neuroscience. vol 10. 2020-10-01. PMID:30581384. |
central to reward processing, learning and goal directed behavior, the lhb has emerged as a critical regulator of the behaviors that are impaired in depression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jiabo Shi, Jiting Geng, Rui Yan, Xiaoxue Liu, Yu Chen, Rongxin Zhu, Xinyi Wang, Junneng Shao, Kun Bi, Ming Xiao, Zhijian Yao, Qing L. Differentiation of Transformed Bipolar Disorder From Unipolar Depression by Resting-State Functional Connectivity Within Reward Circuit. Frontiers in psychology. vol 9. 2020-10-01. PMID:30622492. |
differentiation of transformed bipolar disorder from unipolar depression by resting-state functional connectivity within reward circuit. |
2020-10-01 |
2023-08-13 |
human |
| Jiabo Shi, Jiting Geng, Rui Yan, Xiaoxue Liu, Yu Chen, Rongxin Zhu, Xinyi Wang, Junneng Shao, Kun Bi, Ming Xiao, Zhijian Yao, Qing L. Differentiation of Transformed Bipolar Disorder From Unipolar Depression by Resting-State Functional Connectivity Within Reward Circuit. Frontiers in psychology. vol 9. 2020-10-01. PMID:30622492. |
previous studies have found that neural functional abnormalities detected by functional magnetic resonance imaging (fmri) in brain regions implicated in reward processing during reward tasks show promise to distinguish bipolar from unipolar depression (ud), but little is known regarding resting-state functional connectivity (rsfc) within the reward circuit. |
2020-10-01 |
2023-08-13 |
human |
| Natalia de M Lyra E Silva, Minh P Lam, Claudio N Soares, Douglas P Munoz, Roumen Milev, Fernanda G De Felic. Insulin Resistance as a Shared Pathogenic Mechanism Between Depression and Type 2 Diabetes. Frontiers in psychiatry. vol 10. 2020-10-01. PMID:30837902. |
in this article, we briefly review possible molecular mechanisms associating defective brain insulin signaling with reward system, neurogenesis, synaptic plasticity and hypothalamic-pituitary-adrenal (hpa) stress axis in depression. |
2020-10-01 |
2023-08-13 |
Not clear |
| James F Cavanagh, Andrew W Bismark, Michael J Frank, John J B Alle. Multiple Dissociations Between Comorbid Depression and Anxiety on Reward and Punishment Processing: Evidence From Computationally Informed EEG. Computational psychiatry (Cambridge, Mass.). vol 3. 2020-10-01. PMID:31149639. |
multiple dissociations between comorbid depression and anxiety on reward and punishment processing: evidence from computationally informed eeg. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kristen L Eckstrand, Luis E Flores, Marissa Cross, Jennifer S Silk, Nicholas B Allen, Kati L Healey, Michael P Marshal, Erika E Forbe. Social and Non-social Reward Processing and Depressive Symptoms Among Sexual Minority Adolescents. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31572141. |
alterations in neural reward networks, which develop during adolescence, confer risk for the development of depression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kristen L Eckstrand, Luis E Flores, Marissa Cross, Jennifer S Silk, Nicholas B Allen, Kati L Healey, Michael P Marshal, Erika E Forbe. Social and Non-social Reward Processing and Depressive Symptoms Among Sexual Minority Adolescents. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31572141. |
eight sma and 38 heterosexual typically developing adolescents completed self-report measures of depression and victimization, and underwent fmri during monetary and peer social reward tasks in which they received positive monetary or social feedback, respectively. |
2020-10-01 |
2023-08-13 |
Not clear |