| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher Gagne, Ondrej Zika, Peter Dayan, Sonia J Bisho. Impaired adaptation of learning to contingency volatility in internalizing psychopathology. eLife. vol 9. 2021-03-31. PMID:33350387. |
using a contingency volatility manipulation, we tested the hypothesis that difficulty adapting probabilistic decision-making to second-order uncertainty might reflect a core deficit that cuts across anxiety and depression and holds regardless of whether outcomes are aversive or involve reward gain or loss. |
2021-03-31 |
2023-08-13 |
Not clear |
| Christopher Gagne, Ondrej Zika, Peter Dayan, Sonia J Bisho. Impaired adaptation of learning to contingency volatility in internalizing psychopathology. eLife. vol 9. 2021-03-31. PMID:33350387. |
elevated scores on the common internalizing factor, with high loadings across anxiety and depression items, were linked to impoverished adjustment of learning to volatility regardless of whether outcomes involved reward gain, electrical stimulation, or reward loss. |
2021-03-31 |
2023-08-13 |
Not clear |
| Claudie Gaillard, Matthias Guillod, Monique Ernst, Andrea Federspiel, Dominik Schoebi, Romina Evelyn Recabarren, Xinyi Ouyang, Christoph Mueller-Pfeiffer, Antje Horsch, Philipp Homan, Roland Wiest, Gregor Hasler, Chantal Martin-Soelc. Striatal reactivity to reward under threat-of-shock and working memory load in adults at increased familial risk for major depression: A preliminary study. NeuroImage. Clinical. vol 26. 2021-03-26. PMID:32036303. |
striatal reactivity to reward under threat-of-shock and working memory load in adults at increased familial risk for major depression: a preliminary study. |
2021-03-26 |
2023-08-13 |
Not clear |
| Chaya Shor, Wanhong Zuo, Jean D Eloy, Jiang-Hong Y. The Emerging Role of LHb CaMKII in the Comorbidity of Depressive and Alcohol Use Disorders. International journal of molecular sciences. vol 21. issue 21. 2021-03-26. PMID:33143210. |
recently, interest in the lateral habenula, a small epithalamic brain structure, has increased because it becomes hyperactive in depression and alcohol use disorders, and can inhibit dopamine and serotonin neurons in the midbrain reward center, the hypofunction of which is believed to be a critical contributor to the etiology of depressive disorders and alcohol use disorders as well as their comorbidities. |
2021-03-26 |
2023-08-13 |
Not clear |
| Steven W Kasparek, Jessica L Jenness, Katie A McLaughli. Reward processing modulates the association between trauma exposure and externalizing psychopathology. Clinical psychological science : a journal of the Association for Psychological Science. vol 8. issue 6. 2021-03-26. PMID:33758689. |
the present study examined several behavioral metrics of reward processing reflecting global approach motivation for reward and the degree to which reward responses scaled with reward value (i.e., behavioral sensitivity to reward value) as potential moderators of the association of multiple dimensions of adversity-including trauma, caregiver neglect, and food insecurity-with depression and externalizing psychopathology in a sample of youth aged 8-16 years (n = 132). |
2021-03-26 |
2023-08-13 |
Not clear |
| Adriana Castro-Zavala, Ana Martín-Sánchez, Miguel Ángel Luján, Olga Valverd. Maternal separation increases cocaine intake through a mechanism involving plasticity in glutamate signalling. Addiction biology. vol 26. issue 2. 2021-03-25. PMID:32329565. |
altogether, our results suggest that msew induces molecular alterations in the brain areas related to reward processing, increasing the vulnerability to depression and cocaine-seeking behaviour. |
2021-03-25 |
2023-08-13 |
mouse |
| Joan L Luby, Kirsten Gilbert, Diana Whalen, Rebecca Tillman, Deanna M Barc. The Differential Contribution of the Components of Parent-Child Interaction Therapy Emotion Development for Treatment of Preschool Depression. Journal of the American Academy of Child and Adolescent Psychiatry. vol 59. issue 7. 2021-03-18. PMID:31376501. |
we investigated whether the novel ed module made a unique contribution to the treatment of depression and neural response to reward, and whether child-directed intervention (cdi) and parent-directed intervention (pdi) modules (standard elements of pcit) were also effective. |
2021-03-18 |
2023-08-13 |
Not clear |
| Tsafrir Greenberg, Jay C Fournier, Richelle Stiffler, Henry W Chase, Jorge R Almeida, Haris Aslam, Thilo Deckersbach, Crystal Cooper, Marisa S Toups, Tom Carmody, Benji Kurian, Scott Peltier, Phillip Adams, Melvin G McInnis, Maria A Oquendo, Maurizio Fava, Ramin Parsey, Patrick J McGrath, Myrna Weissman, Madhukar Trivedi, Mary L Phillip. Reward related ventral striatal activity and differential response to sertraline versus placebo in depressed individuals. Molecular psychiatry. vol 25. issue 7. 2021-03-17. PMID:31462766. |
we tested whether an index of reward system function in the ventral striatum (vs), a key reward circuitry region, moderated differential response to sertraline versus placebo, assessed with the hamilton rating scale for depression (hsrd) over 8 weeks. |
2021-03-17 |
2023-08-13 |
Not clear |
| Tsafrir Greenberg, Jay C Fournier, Richelle Stiffler, Henry W Chase, Jorge R Almeida, Haris Aslam, Thilo Deckersbach, Crystal Cooper, Marisa S Toups, Tom Carmody, Benji Kurian, Scott Peltier, Phillip Adams, Melvin G McInnis, Maria A Oquendo, Maurizio Fava, Ramin Parsey, Patrick J McGrath, Myrna Weissman, Madhukar Trivedi, Mary L Phillip. Reward related ventral striatal activity and differential response to sertraline versus placebo in depressed individuals. Molecular psychiatry. vol 25. issue 7. 2021-03-17. PMID:31462766. |
we observed a significant moderation effect of the reward index, reflecting the temporal dynamics of vs activity, on week-8 depression levels (fs ≥ 9.67, ps ≤ 0.002). |
2021-03-17 |
2023-08-13 |
Not clear |
| Megan E Fox, Ramesh Chandra, Miriam S Menken, Emily J Larkin, Hyungwoo Nam, Michel Engeln, T Chase Francis, Mary Kay Lob. Dendritic remodeling of D1 neurons by RhoA/Rho-kinase mediates depression-like behavior. Molecular psychiatry. vol 25. issue 5. 2021-03-16. PMID:30120419. |
depression alters the structure and function of brain reward circuitry. |
2021-03-16 |
2023-08-13 |
mouse |
| Kelly T Cosgrove, Kaiping Burrows, Jason A Avery, Kara L Kerr, Danielle C DeVille, Robin L Aupperle, T Kent Teague, Wayne C Drevets, W Kyle Simmon. Appetite change profiles in depression exhibit differential relationships between systemic inflammation and activity in reward and interoceptive neurocircuitry. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31604141. |
appetite change profiles in depression exhibit differential relationships between systemic inflammation and activity in reward and interoceptive neurocircuitry. |
2021-03-08 |
2023-08-13 |
human |
| Gabrielle I Liverant, Kimberly A Arditte Hall, Sarah T Wieman, Suzanne L Pineles, Diego A Pizzagall. Associations between insomnia and reward learning in clinical depression. Psychological medicine. 2021-02-26. PMID:33634765. |
recent research and theory highlight reward system dysfunction as a potential mediator of the relationship between insomnia and depression. |
2021-02-26 |
2023-08-13 |
Not clear |
| Gabrielle I Liverant, Kimberly A Arditte Hall, Sarah T Wieman, Suzanne L Pineles, Diego A Pizzagall. Associations between insomnia and reward learning in clinical depression. Psychological medicine. 2021-02-26. PMID:33634765. |
this study is the first to examine the impact of insomnia on reward learning, a key component of reward system functioning, in clinical depression. |
2021-02-26 |
2023-08-13 |
Not clear |
| Nastaran Mansouriyeh, Majid Mahmoud-Aliloo, Reza Rostam. The Effect of High-frequency Repetitive Transcranial Magnetic Stimulation on Reducing Depression and Anxiety in Methamphetamine Users. Addiction & health. vol 12. issue 4. 2021-02-25. PMID:33623647. |
the mesocorticolimbic dopaminergic reward system seems to play a crucial role in inducing depression and anxiety in methamphetamine users. |
2021-02-25 |
2023-08-13 |
Not clear |
| Clara Liao, Alex C Kwa. Applying Reinforcement Learning to Rodent Stress Research. Chronic stress (Thousand Oaks, Calif.). vol 5. 2021-02-20. PMID:33598593. |
in this commentary, we suggest that learning tasks, particularly those that can be analyzed with the framework of reinforcement learning, are ideal for assaying reward processing deficits relevant to depression. |
2021-02-20 |
2023-08-13 |
Not clear |
| Dahlia Mukherjee, Alexandre L S Filipowicz, Khoi Vo, Theodore D Satterthwaite, Joseph W Kabl. Reward and punishment reversal-learning in major depressive disorder. Journal of abnormal psychology. vol 129. issue 8. 2021-02-16. PMID:33001663. |
depression has been associated with impaired reward and punishment processing, but the specific nature of these deficits is still widely debated. |
2021-02-16 |
2023-08-13 |
Not clear |
| Leonardo Tozzi, Brooke Staveland, Bailey Holt-Gosselin, Megan Chesnut, Sarah E Chang, David Choi, Melissa Shiner, Hua Wu, Garikoitz Lerma-Usabiaga, Olaf Sporns, Deanna M Barch, Ian H Gotlib, Trevor J Hastie, Adam B Kerr, Russell A Poldrack, Brian A Wandell, Max Wintermark, Leanne M William. The human connectome project for disordered emotional states: Protocol and rationale for a research domain criteria study of brain connectivity in young adult anxiety and depression. NeuroImage. vol 214. 2021-02-15. PMID:32147367. |
we focus on three rdoc domains and constructs most relevant to depression and anxiety: 1) loss and acute threat within the negative valence system (nvs) domain; 2) reward valuation and responsiveness within the positive valence system (pvs) domain; and 3) working memory and cognitive control within the cognitive system (cs) domain. |
2021-02-15 |
2023-08-13 |
human |
| Paige Ethridge, Clara Freeman, Aislinn Sandre, Iulia Banica, Melanie A Dirks, Anna Weinber. Intergenerational transmission of depression risk: Mothers' neural response to reward and history of depression are associated with daughters' neural response to reward across adolescence. Journal of abnormal psychology. 2021-02-04. PMID:33539114. |
intergenerational transmission of depression risk: mothers' neural response to reward and history of depression are associated with daughters' neural response to reward across adolescence. |
2021-02-04 |
2023-08-13 |
Not clear |
| Paige Ethridge, Clara Freeman, Aislinn Sandre, Iulia Banica, Melanie A Dirks, Anna Weinber. Intergenerational transmission of depression risk: Mothers' neural response to reward and history of depression are associated with daughters' neural response to reward across adolescence. Journal of abnormal psychology. 2021-02-04. PMID:33539114. |
impaired reward responsiveness, a construct of the rdoc positive valence systems (pvs), prospectively predicts depression onset and may therefore represent an important marker of risk. |
2021-02-04 |
2023-08-13 |
Not clear |
| Gina Lc Yosten, Caron M Harada, Chris Haddock, Luigino Antonio Giancotti, Grant R Kolar, Ryan Patel, Chun Guo, Zhoumou Chen, Jinsong Zhang, Timothy M Doyle, Anthony H Dickenson, Willis K Samson, Daniela Salvemin. GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents. The Journal of clinical investigation. vol 130. issue 5. 2021-02-03. PMID:31999650. |
cartp is involved in many diseases including depression and reward and addiction; de-orphanization of gpr160 is a major step forward understanding the role of cartp signaling in health and disease. |
2021-02-03 |
2023-08-13 |
Not clear |