| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Y Coe, D Loundes, F Coceani, P M Olle. The circulatory effects of nifedipine in the conscious newborn lamb. Pediatric research. vol 20. issue 1. 1986-03-21. PMID:3945511. |
nifedipine causes significant cardiac depression combined with systemic vasodilatation and pulmonary arteriolar constriction in conscious newborn lambs. |
1986-03-21 |
2023-08-11 |
Not clear |
| E Vatashsky, B Beilin, M Razin, M Weinstoc. Mechanism of antagonism by physostigmine of acute flunitrazepam intoxication. Anesthesiology. vol 64. issue 2. 1986-03-05. PMID:3004260. |
the effect of physostigmine on the loss of consciousness and respiratory depression induced in rabbits by flunitrazepam, 1 mg/kg, was studied to demonstrate whether the restoration of consciousness and respiration rate results from an increase in central cholinergic activity or from an interference by physostigmine with specific binding of flunitrazepam to its receptors. |
1986-03-05 |
2023-08-11 |
rabbit |
| P J Shaw, D Bates, N E Cartlidge, D Heaviside, D G Julian, D A Sha. Early neurological complications of coronary artery bypass surgery. British medical journal (Clinical research ed.). vol 291. issue 6506. 1986-01-09. PMID:2998539. |
prolonged depression of conscious level was observed in 10 patients (3%) and definite stroke in 15 (5%); 78 (25%) developed ophthalmological abnormalities and 123 (39%) primitive reflexes; postoperative psychosis was observed in four (1%); and 37 (12%) developed disorders of the peripheral nervous system. |
1986-01-09 |
2023-08-11 |
Not clear |
| D T Wade, R L Hewe. Outlook after an acute stroke: urinary incontinence and loss of consciousness compared in 532 patients. The Quarterly journal of medicine. vol 56. issue 221. 1985-12-05. PMID:4059507. |
data from a sample of 532 patients seen within seven days of an acute stroke has been analysed to compare the prognostic importance of urinary incontinence with that of a history of any depression of consciousness. |
1985-12-05 |
2023-08-11 |
Not clear |
| E H Roland, G Lockitch, H G Dunn, D Peacock, G E Piri. Methadone poisoning due to accidental contamination of prescribed medication. Canadian Medical Association journal. vol 131. issue 11. 1985-01-14. PMID:6498687. |
two infants presented with fever and signs of brainstem dysfunction, including impaired consciousness, miosis, absence of oculocephalic responses, respiratory depression and a very peculiar tremor of the tongue and floor of the mouth. |
1985-01-14 |
2023-08-12 |
Not clear |
| K Nishie, W Fiddler, J W Pensaben. Comparison of the acute toxicities of N-nitrosothiazolidine and N-nitrosomorpholine. Journal of toxicology and environmental health. vol 13. issue 4-6. 1984-11-28. PMID:6492189. |
lethal and near-lethal doses (greater than or equal to 1500 mg/kg, po) of nnt caused central nervous system depression (reduced spontaneous motor activity, loss of righting and pain reflexes, without loss of consciousness), stereotypical behavior such as, purposeless chewing jaw movements lasting more than one hour, muscular rigidity, and in some rats, rare and brief clonic convulsions, 3 to 24 h after dosing. |
1984-11-28 |
2023-08-12 |
rat |
| M Bernstein, R A Hegele, F Gentili, M Brothers, R Holgate, W C Sturtridge, J Dec. Pituitary apoplexy associated with a triple bolus test. Case report. Journal of neurosurgery. vol 61. issue 3. 1984-09-19. PMID:6431060. |
the authors report a case of pituitary apoplexy resulting in bilateral internal carotid artery occlusion, with marked depression of consciousness and hemiplegia. |
1984-09-19 |
2023-08-12 |
Not clear |
| B R Pit. Metabolic functions of the lung and systemic vasoregulation. Federation proceedings. vol 43. issue 11. 1984-09-05. PMID:6086408. |
given to conscious rabbits caused prolonged depression in pulmonary ace activity, an effect that coincided with a significant reduction in mean systemic arterial pressure. |
1984-09-05 |
2023-08-12 |
Not clear |
| G K Gourlay, R J Willis, P R Wilso. Postoperative pain control with methadone: influence of supplementary methadone doses and blood concentration--response relationships. Anesthesiology. vol 61. issue 1. 1984-07-31. PMID:6742480. |
the criteria established for the administration of supplementary methadone doses were the co-existence of 1) spontaneous reporting of significant pain by the patient; 2) an unstimulated respiratory rate of greater than 10 breaths/min, and 3) no significant depression of the level of consciousness. |
1984-07-31 |
2023-08-12 |
Not clear |
| C M Alle. Predicting the outcome of acute stroke: a prognostic score. Journal of neurology, neurosurgery, and psychiatry. vol 47. issue 5. 1984-07-30. PMID:6736978. |
the features which were found to predict functional dependence or death included older age, complete limb paralysis, depression of conscious level and the combination of hemiplegia and hemianopia with higher cerebral dysfunction. |
1984-07-30 |
2023-08-12 |
Not clear |
| M J Kelner, D N Baile. Ethchlorvynol ingestion: interpretation of blood concentrations and clinical findings. Journal of toxicology. Clinical toxicology. vol 21. issue 3. 1984-07-26. PMID:6676479. |
for the "pure" cases the most common physical findings were depressed level of consciousness (10 cases), dysarthria (7), mydriasis (6), nystagmus (6), areflexia (4), tachycardia (4), and hypotension, ataxia, and respiratory depression (2 cases each). |
1984-07-26 |
2023-08-12 |
Not clear |
| W K Samson, M D Lumpkin, G Nilaver, S M McCan. Motilin: a novel growth hormone releasing agent. Brain research bulletin. vol 12. issue 1. 1984-06-01. PMID:6424871. |
furthermore, infusion of motilin into the third ventricle of conscious rats resulted in a significant depression of gh levels, suggesting an ultrashort loop feedback action of motilin on the release of motilin itself or somatostatin. |
1984-06-01 |
2023-08-12 |
human |
| S Gottlieb, A Taylo. Interpretation of fusimotor activity in cat masseter nerve during reflex jaw movements. The Journal of physiology. vol 345. 1984-03-07. PMID:6229627. |
this increase during shortening is not usually seen in conscious animals and reasons are given for the view that it is due to greater depression of alpha-motor activity than of static fusimotor activity during anaesthesia. |
1984-03-07 |
2023-08-12 |
cat |
| S Motomura, I Kissin, D F Aultman, J G Reve. Effects of fentanyl and nitrous oxide on contractility of blood-perfused papillary muscle of the dog. Anesthesia and analgesia. vol 63. issue 1. 1984-02-24. PMID:6691564. |
with a conscious donor, fentanyl infused directly into the arterial blood perfusing the papillary muscle produced a dose-related depression of developed tension. |
1984-02-24 |
2023-08-12 |
dog |
| M Falcy, G Riboulet-Delmas, M L Efthymio. [Acute poisoning by viloxazine chlorhydrate taken by itself]. L'Encephale. vol 9. issue 2. 1984-01-07. PMID:6641615. |
the depression of the central nervous system was characterised only by a transitory loss of consciousness with recovery within a few hours. |
1984-01-07 |
2023-08-12 |
Not clear |
| J L Bergey, T Sulkowski, D R Much, R L Wend. Antiarrhythmic, hemodynamic and cardiac electrophysiological evaluation of N-(2,6-dimethylphenyl)-N'-[3-(1-methylethylamino)propyl]urea (Wy-42,362). Arzneimittel-Forschung. vol 33. issue 9. 1983-12-20. PMID:6685506. |
wy produced a generalized depression of cardiac impulse conduction in open-chest, pentobarbital anesthetized dogs but conscious dogs exhibited relatively little ecg evidence of such depression following double the therapeutic i.v. |
1983-12-20 |
2023-08-12 |
Not clear |
| L A Walker, M Buscemi-Bergin, M Gella. Renal hemodynamics in conscious rats: effects of anesthesia, surgery, and recovery. The American journal of physiology. vol 245. issue 1. 1983-08-11. PMID:6869539. |
in addition, the "conscious" preparation commonly used for renal studies in rats, i.e., one involving experimentation 2-3 h after ether anesthesia and surgery, is associated with a severe depression of renal hemodynamics. |
1983-08-11 |
2023-08-12 |
rat |
| M Zimpfer, H Gilly, P Krösl, G Schlag, K Steinbereithne. Importance of myocardial loading conditions in determining the effects of enflurane on left ventricular function in the intact and isolated canine heart. Anesthesiology. vol 58. issue 2. 1983-03-11. PMID:6824170. |
in intact dogs with aortic pressure artificially increased to conscious control levels, enflurane likewise caused a distinct depression of the lv diastolic performance. |
1983-03-11 |
2023-08-12 |
Not clear |
| M Artman, R C Boert. Clonidine poisoning. A complex problem. American journal of diseases of children (1960). vol 137. issue 2. 1983-02-25. PMID:6849304. |
the most frequent and significant toxic effects are depression of consciousness, bradycardia, hypotension, and respiratory depression. |
1983-02-25 |
2023-08-12 |
Not clear |
| E Freye, E Hartung, G K Schen. Perfusion of the fourth cerebral ventricle with the synthetic opioid peptide, FK 33-824, induces dose-related bradycardia and naloxone-reversible respiratory depression in the awake dog. Pharmacology. vol 25. issue 1. 1982-12-02. PMID:7122692. |
increasing concentrations (20, 100, 200 and 400 micrograms/ml), perfused through the 4th cerebral ventricle of the conscious dog, induced a concentration-related depression of respiratory function - as reflected in arterial pco2 and po2 and heart rate. |
1982-12-02 |
2023-08-12 |
dog |