| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K M Wu, W R Marti. Cardiovascular and respiratory effects of an opioid kappa agonist ethylketazocine and sigma agonist N-allylnormetazocine in acutely decerebrated dogs. Pharmacology, biochemistry, and behavior. vol 34. issue 2. 1990-03-27. PMID:2695944. |
since ekc- and nanm-induced cardiovascular and respiratory depression were not observed in conscious intact or chronic spinal dog, it is suggested that: 1) kappaergic system rostral to mesencephalon may play a role in counteracting these depressant effects of ekc; 2) sigma receptor-mediated tachypnea and tachycardia are dissociable; the tachypneic effect may be mediated through higher center while the medulla oblongata is involved in producing tachycardia. |
1990-03-27 |
2023-08-11 |
dog |
| W J French, D Garner, G E Adomian, W Averill, M M Lak. Verapamil induced ventricular hypertrophy in conscious dogs. Cardiovascular research. vol 23. issue 8. 1990-02-06. PMID:2532064. |
in conclusion, a chronic infusion of verapamil in conscious dogs caused no change in resting haemodynamic variables but produced reversible depression of stress ventricular function and biventricular and septal hypertrophy. |
1990-02-06 |
2023-08-11 |
Not clear |
| T Mochizuki, Y Kawaue, I Imura, S Wada, T Tsuchiy. [A study of left ventricular rupture associated with acute myocardial infarction]. [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai. vol 37. issue 1. 1989-07-25. PMID:2732535. |
in the intermediate type, there is depression of blood pressure to the level of losing consciousness but improvement of blood pressure and consciousness through medical treatment and time is available to permit surgical treatment in comparison with the blow out type. |
1989-07-25 |
2023-08-11 |
Not clear |
| J Deit. Self-psychological interventions for major depression: technique and theory. American journal of psychotherapy. vol 42. issue 4. 1989-02-10. PMID:3213848. |
after defining the relevant self-psychological terms, we discuss the factors influencing emergence into consciousness of these positive affects and effects on the patient's vegetative symptoms of depression during self-psychologically oriented psychotherapy. |
1989-02-10 |
2023-08-11 |
Not clear |
| L E McCoy, L A Elliott, C E Lucas, A M Ledgerwoo. Regenerative responses to exchange perfusion. Biomaterials, artificial cells, and artificial organs. vol 16. issue 1-3. 1988-12-08. PMID:3179490. |
isovolemic exchange perfusion of conscious normal and splenectomized rats to a hct of +/- 3% with the perfluorocarbon based oxygen transport fluid, fluosol-da 20%, is characterized by: 1) a greater than projected depression of fibrinogen and the plasma globulins and 2) a rapid regeneration of these and certain other plasma proteins. |
1988-12-08 |
2023-08-11 |
rat |
| S Nishio, H Matsuura, N Kanai, Y Fukatsu, T Hirano, N Nishikawa, K Kameoka, T Umets. The in vitro and ex vivo antiplatelet effect of TRK-100, a stable prostacyclin analog, in several species. Japanese journal of pharmacology. vol 47. issue 1. 1988-10-06. PMID:2842529. |
in anesthetized rabbits, inhibition of platelet aggregation was the same level as in the conscious animal, but blood pressure depression was observed. |
1988-10-06 |
2023-08-11 |
human |
| M J Eadie, W D Hooper, R G Dickinso. Valproate-associated hepatotoxicity and its biochemical mechanisms. Medical toxicology and adverse drug experience. vol 3. issue 2. 1988-07-14. PMID:3131628. |
the typical presentation is of worsening epilepsy, increasing depression of consciousness, and progressive clinical and biochemical evidence of liver failure. |
1988-07-14 |
2023-08-11 |
Not clear |
| M Beise. Changing time perspective and mental health among Southeast Asian refugees. Culture, medicine and psychiatry. vol 11. issue 4. 1988-02-16. PMID:3691162. |
the reemergence of past and future into consciousness brings about a risk for developing depression. |
1988-02-16 |
2023-08-11 |
Not clear |
| R J Applegate, R A Walsh, R A O'Rourk. Frequency-dependent myocardial depression induced by verapamil in conscious dogs. The American journal of physiology. vol 253. issue 3 Pt 2. 1987-10-22. PMID:3631287. |
frequency-dependent myocardial depression induced by verapamil in conscious dogs. |
1987-10-22 |
2023-08-11 |
Not clear |
| R G Matschk. [Allergic reaction in therapy with naftidrofuryl (Dusodril). A case report]. HNO. vol 35. issue 5. 1987-08-28. PMID:3610682. |
side effects are only reported rarely, and include decrease of cerebral blood flow, abdominal distension, diarrhoea, oesophageal ulceration, epileptic seizures, aphasia, disturbances of consciousness, hypotension, hypertensive crisis, vertigo and dizziness, depression of cardiac conduction, thrombophlebitis, and allergy. |
1987-08-28 |
2023-08-11 |
Not clear |
| R S el-Mallak. Acute lithium neurotoxicity. Psychiatric developments. vol 4. issue 4. 1987-06-09. PMID:3575317. |
cns depression is reflected in decreased upper motor neuron control, decreased level of consciousness, and slowing on the electroencephalogram. |
1987-06-09 |
2023-08-11 |
Not clear |
| R A Conn, R H Cofield, D E Byer, J W Linstromber. Interscalene block anesthesia for shoulder surgery. Clinical orthopaedics and related research. issue 216. 1987-04-13. PMID:3815976. |
complications from high blood levels of anesthetic included loss of consciousness and respiratory depression in three patients and seizure in one. |
1987-04-13 |
2023-08-11 |
Not clear |
| J F Bion, B K Logan, P M Newman, M J Brodie, J S Oliver, T C Aitchison, I M Ledingha. Sedation in intensive care: morphine and renal function. Intensive care medicine. vol 12. issue 5. 1986-12-10. PMID:3771914. |
conscious level was clearly more closely related to the degree of physiological disturbance than blood morphine levels; and for a given blood morphine level, depression of consciousness was more pronounced the greater the degree of physiological disturbance. |
1986-12-10 |
2023-08-11 |
Not clear |
| A F Altimari, R A Prinz, D W Leutz, L Sandberg, P M Kober, R M Raymon. Myocardial depression during acute pancreatitis: fact or fiction? Surgery. vol 100. issue 4. 1986-10-30. PMID:3764695. |
myocardial performance as assessed by ees was significantly increased and myocardial depression did not occur in untreated, conscious dogs with severe pancreatitis. |
1986-10-30 |
2023-08-11 |
Not clear |
| A Poizot, D Dumez, P Ferrandon, C Lefournier, A Michel, J M Armstron. Animal pharmacology of the selective histamine H1-receptor antagonist tazifylline. Arzneimittel-Forschung. vol 36. issue 4. 1986-07-17. PMID:2424463. |
large oral doses of tazifylline did not reduce spontaneous locomotor activity in mice, nor did they produce overt symptoms of behavioral depression in conscious rats. |
1986-07-17 |
2023-08-11 |
mouse |
| C R Kennedy, K Chrzanowska, R O Robinson, D A Tyrrell, H B Valman, A D Webste. A major role for viruses in acute childhood encephalopathy. Lancet (London, England). vol 1. issue 8488. 1986-06-06. PMID:2422512. |
29 children and 3 adults with acute depression of conscious level or acute onset of focal neurological signs were studied prospectively. |
1986-06-06 |
2023-08-11 |
Not clear |
| W M Abraham, M W Sielczak, J C Delehunt, B Marchette, A Wanne. Impairment of tracheal mucociliary clearance but not ciliary beat frequency by a combination of low level ozone and sulfur dioxide in sheep. European journal of respiratory diseases. vol 68. issue 2. 1986-06-06. PMID:3699114. |
we conclude that in conscious sheep, exposure to a combination of low level o3 and so2 causes a depression in tmv, and changes in cbf are probably not a primary cause of this mucociliary dysfunction. |
1986-06-06 |
2023-08-11 |
Not clear |
| A H Roppe. Lateral displacement of the brain and level of consciousness in patients with an acute hemispheral mass. The New England journal of medicine. vol 314. issue 15. 1986-04-28. PMID:3960059. |
studies were performed soon after the appearance of the mass to detect the earliest ct changes associated with depression of consciousness. |
1986-04-28 |
2023-08-11 |
Not clear |
| J Y Coe, D Loundes, F Coceani, P M Olle. The circulatory effects of nifedipine in the conscious newborn lamb. Pediatric research. vol 20. issue 1. 1986-03-21. PMID:3945511. |
nifedipine causes significant cardiac depression combined with systemic vasodilatation and pulmonary arteriolar constriction in conscious newborn lambs. |
1986-03-21 |
2023-08-11 |
Not clear |
| E Vatashsky, B Beilin, M Razin, M Weinstoc. Mechanism of antagonism by physostigmine of acute flunitrazepam intoxication. Anesthesiology. vol 64. issue 2. 1986-03-05. PMID:3004260. |
the effect of physostigmine on the loss of consciousness and respiratory depression induced in rabbits by flunitrazepam, 1 mg/kg, was studied to demonstrate whether the restoration of consciousness and respiration rate results from an increase in central cholinergic activity or from an interference by physostigmine with specific binding of flunitrazepam to its receptors. |
1986-03-05 |
2023-08-11 |
rabbit |