| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas MacInnes, Mahmoud M Iravani, Elaine Perry, Margaret Piggott, Robert Perry, Peter Jenner, Clive Ballar. Proteasomal abnormalities in cortical Lewy body disease and the impact of proteasomal inhibition within cortical and cholinergic systems. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 6. 2008-10-03. PMID:18401540. |
analysis of post-mortem cortical tissue indicated levels of the alpha-subunit of the 20s proteasome were significantly reduced in dlb cortex, but not alzheimer's, in comparison to control and this reduction correlated with both the severity and duration of dementia. |
2008-10-03 |
2023-08-12 |
Not clear |
| Carles Gaig, Mario Ezquerra, Maria José Martí, Francesc Valldeoriola, Esteban Muñoz, Albert Lladó, Maria Jesús Rey, Adriana Cardozo, José Luis Molinuevo, Eduardo Tolos. Screening for the LRRK2 G2019S and codon-1441 mutations in a pathological series of parkinsonian syndromes and frontotemporal lobar degeneration. Journal of the neurological sciences. vol 270. issue 1-2. 2008-09-24. PMID:18353371. |
while the prevalence of lrrk2 mutations has been extensively studied in parkinson's disease (pd), limited information is available on the frequency of lrrk2 mutations in dementia with lewy bodies (dlb) and in other pathological conditions associated with these mutations, such as non-specific nigral degeneration without lb, tau-immunopositive neurofibrillary tangle pathology, and ubiquitin-positive neuronal inclusions resembling those observed in a subtype of frontotemporal lobar degeneration (ftld-u). |
2008-09-24 |
2023-08-12 |
Not clear |
| Hsing-Cheng Liu, Chaur-Jong Hu, Yun-Chin Tang, Jan-Gowth Chan. A pilot study for circadian gene disturbance in dementia patients. Neuroscience letters. vol 435. issue 3. 2008-09-24. PMID:18358604. |
dementia with lewy body (dlb) patients had the significantly highest frequency of circadian gene cpg island methylation (35.7%). |
2008-09-24 |
2023-08-12 |
Not clear |
| Hsing-Cheng Liu, Chaur-Jong Hu, Yun-Chin Tang, Jan-Gowth Chan. A pilot study for circadian gene disturbance in dementia patients. Neuroscience letters. vol 435. issue 3. 2008-09-24. PMID:18358604. |
it suggested that epigenetic methylation of circadian gene was more prevalent in dementia patients, especially for the dlb patients. |
2008-09-24 |
2023-08-12 |
Not clear |
| Hiroshige Fujishiro, Tanis J Ferman, Bradley F Boeve, Glenn E Smith, Neill R Graff-Radford, Ryan J Uitti, Zbigniew K Wszolek, David S Knopman, Ronald C Petersen, Joseph E Parisi, Dennis W Dickso. Validation of the neuropathologic criteria of the third consortium for dementia with Lewy bodies for prospectively diagnosed cases. Journal of neuropathology and experimental neurology. vol 67. issue 7. 2008-09-19. PMID:18596548. |
in this study, the core clinical features of dementia with lewy bodies (dlb) and the suggestive clinical feature of rapid eye movement sleep behavior disorder were assessed using a battery of standardized clinical instruments in 76 patients with the clinical diagnosis of either dlb or alzheimer disease. |
2008-09-19 |
2023-08-12 |
Not clear |
| Kouhei Fujimi, Kensuke Sasaki, Kazuhito Noda, Yoshinobu Wakisaka, Yumihiro Tanizaki, Yukiko Matsui, Atsuko Sekita, Mitsuo Iida, Yutaka Kiyohara, Shigenobu Kanba, Toru Iwak. Clinicopathological outline of dementia with Lewy bodies applying the revised criteria: the Hisayama study. Brain pathology (Zurich, Switzerland). vol 18. issue 3. 2008-08-26. PMID:18462473. |
to explore the validity of the criteria for dementia with lewy bodies (dlb) revised in 2005, we examined community based consecutive autopsy cases. |
2008-08-26 |
2023-08-12 |
human |
| Carolyn W Zhu, Nikolaos Scarmeas, Karina Stavitsky, Marilyn Albert, Jason Brandt, Deborah Blacker, Mary Sano, Yaakov Ster. Comparison of costs of care between patients with Alzheimer's disease and dementia with Lewy bodies. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 4. issue 4. 2008-08-26. PMID:18631979. |
the objective of this study was to compare total costs of care and its major components for community-living patients with alzheimer's disease (ad) or dementia with lewy bodies (dlb). |
2008-08-26 |
2023-08-12 |
Not clear |
| Robert A Koeppe, Sid Gilman, Larry Junck, Kris Wernette, Kirk A Fre. Differentiating Alzheimer's disease from dementia with Lewy bodies and Parkinson's disease with (+)-[11C]dihydrotetrabenazine positron emission tomography. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 4. issue 1 Suppl 1. 2008-08-26. PMID:18632004. |
several progressive neurologic disorders begin with cognitive decline or parkinsonism, notably alzheimer's disease (ad), parkinson's disease (pd), and dementia with lewy bodies (dlb). |
2008-08-26 |
2023-08-12 |
Not clear |
| Sara Friederike Gloeckner, Felix Meyne, Fabian Wagner, Uta Heinemann, Anna Krasnianski, Bettina Meissner, Inga Zer. Quantitative analysis of transthyretin, tau and amyloid-beta in patients with dementia. Journal of Alzheimer's disease : JAD. vol 14. issue 1. 2008-08-18. PMID:18525124. |
we carried out a quantitative analysis of transthyretin (ttr), total tau protein and amyloid-beta (abeta) peptide (1-40 and 1-42) in the lumbar cerebrospinal fluid of 106 patients with different forms of dementia including alzheimer's disease (ad), creutzfeldt-jakob-disease (cjd), dementia with lewy bodies (dlb), frontotemporal dementia (ftd) and normal pressure hydrocephalus (nph) in comparison to healthy controls. |
2008-08-18 |
2023-08-12 |
Not clear |
| Vincenzo Bonifat. Recent advances in the genetics of dementia with lewy bodies. Current neurology and neuroscience reports. vol 8. issue 3. 2008-08-18. PMID:18541113. |
in the past few years, mutations have been identified in the genes encoding alpha-synuclein, leucine-rich repeat kinase 2, and glucocerebrosidase in some patients with dementia with lewy bodies (dlb). |
2008-08-18 |
2023-08-12 |
Not clear |
| M Andersson, O Hansson, L Minthon, C G Ballard, E Londo. The period of hypotension following orthostatic challenge is prolonged in dementia with Lewy bodies. International journal of geriatric psychiatry. vol 23. issue 2. 2008-08-13. PMID:17621385. |
to determine whether orthostatic hypotension (oh) is more common in patients with dementia than in older people without cognitive impairment and to identify key differences in the profile of the orthostatic response and the pulse drive during orthostatic challenge between alzheimer's disease (ad) and dementia with lewy bodies (dlb). |
2008-08-13 |
2023-08-12 |
Not clear |
| Seiju Kobayashi, Masaru Tateno, Yoshimori Furukawa, Tomohiko Shirasaka, Kumiko Utum. [Improved diagnosis of dementia with Lewy bodies by the combination of 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy and 99mTc-ethylcysteinate dimmer (ECD) brain perfusion SPECT]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 110. issue 4. 2008-08-12. PMID:18593002. |
clinical diagnostic criteria for dementia with lewy bodies (dlb) include abnormal findings on mibg myocardial scintigraphy and occipital hypoperfusion as supportive features. |
2008-08-12 |
2023-08-12 |
Not clear |
| F Carrillo García, E Gil Néciga, R Alberca, D García-Solís, J Millán, J J Rodríguez Uranga, E Franco, P Mir, A Suárez, R García, A Serrano-Pozo, H Pérez-Díaz, J Pol. [Apolipoprotein E4 in dementia with Lewy bodies]. Neurologia (Barcelona, Spain). vol 23. issue 3. 2008-08-11. PMID:18370334. |
the association between apoe4 and dementia with lewy bodies (dlb) is under discussion. |
2008-08-11 |
2023-08-12 |
Not clear |
| G Muntané, E Dalfó, A Martinez, I Ferre. Phosphorylation of tau and alpha-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related alpha-synucleinopathies. Neuroscience. vol 152. issue 4. 2008-08-07. PMID:18343584. |
phosphorylation of tau and phosphorylation of alpha-synuclein are crucial abnormalities in alzheimer's disease (ad) and alpha-synucleinopathies (parkinson's disease: pd, and dementia with lewy bodies: dlb), respectively. |
2008-08-07 |
2023-08-12 |
mouse |
| Marisa Saldaña, Laura Pujols, Jordi Roca-Ferrer, Adriana Cardozo, Esther Aguilar, Mercè Bonastre, Concepció Mari. Relevance of COX-2 gene expression in dementia with lewy bodies associated with Alzheimer pathology. Movement disorders : official journal of the Movement Disorder Society. vol 23. issue 6. 2008-08-06. PMID:18307244. |
the aim of the present study was to investigate whether cyclooxygenase-2 (cox-2) expression is involved in the pathogenesis of neurodegeneration in dementia with lewy bodies (dlb) by measuring cox-2 mrna and protein expression in frontal cortex and substantia nigra pars compacta of dlb and control human brains. |
2008-08-06 |
2023-08-12 |
human |
| Richard A Armstron. Visual signs and symptoms of Parkinson's disease. Clinical & experimental optometry. vol 91. issue 2. 2008-08-05. PMID:18271776. |
moreover, visual testing is useful in separating pd from other movement disorders with visual symptoms, such as dementia with lewy bodies (dlb), multiple system atrophy (msa) and progressive supranuclear palsy (psp). |
2008-08-05 |
2023-08-12 |
Not clear |
| Thomas Gerald Beach, Charles H Adler, Lucia I Sue, Jeffrey B Peirce, Jyothi Bachalakuri, Jessica E Dalsing-Hernandez, Lih Fen Lue, John N Caviness, Donald J Connor, Marwan N Sabbagh, Douglas G Walke. Reduced striatal tyrosine hydroxylase in incidental Lewy body disease. Acta neuropathologica. vol 115. issue 4. 2008-08-01. PMID:17985144. |
it has been speculated that ilbd represents the preclinical stage of parkinson's disease (pd) and/or dementia with lewy bodies (dlb). |
2008-08-01 |
2023-08-12 |
human |
| Kurt A Jellinger, Johannes Attem. Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease. Acta neuropathologica. vol 115. issue 4. 2008-08-01. PMID:18273624. |
a retrospective clinico-pathologic study of 100 patients with autopsy proven pd (including 44 cases with dementia/pdd) and 20 cases of dementia with lewy bodies (dlb) confirmed essential clinical (duration of illness, mini-mental state examination/mmse, age at death) and morphologic differences between these groups; lewy body braak scores and alzheimer pathologies (neuritic braak stage, cortical abeta plaque load, and generalized cerebral amyloid angiopathy or caa) were significantly higher/more severe in dlb and pdd than in pd without dementia. |
2008-08-01 |
2023-08-12 |
human |
| Laura Parkkinen, Tuula Pirttilä, Irina Alafuzof. Applicability of current staging/categorization of alpha-synuclein pathology and their clinical relevance. Acta neuropathologica. vol 115. issue 4. 2008-08-01. PMID:18297293. |
in parkinson's disease (pd) and dementia with lewy bodies (dlb) alpha-synuclein (alphas) pathology is seen that displays a predictable topographic distribution. |
2008-08-01 |
2023-08-12 |
human |
| Sebastiaan Engelborghs, Ellen Vloeberghs, Nathalie Le Bastard, Michael Van Buggenhout, Peter Mariën, Nore Somers, Guy Nagels, Barbara A Pickut, Peter P De Dey. The dopaminergic neurotransmitter system is associated with aggression and agitation in frontotemporal dementia. Neurochemistry international. vol 52. issue 6. 2008-07-28. PMID:18093695. |
patients with probable alzheimer's disease (ad) (n=181), mixed dementia (mxd) (n=28), frontotemporal dementia (ftd) (n=25) and dementia with lewy bodies (dlb) (n=24) were included. |
2008-07-28 |
2023-08-12 |
Not clear |