Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
S G Choi, T Tittle, R Barot, D Betts, J Gallagher, J H Kordower, Y Chu, B A Killinge. Comparing alpha-synuclein-interactomes between multiple systems atrophy and Parkinson's disease reveals unique and shared pathological features. bioRxiv : the preprint server for biology. 2024-09-30. PMID:39345456. |
primary synucleinopathies, such as parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa), are neurodegenerative disorders with some shared clinical and pathological features. |
2024-09-30 |
2024-10-02 |
Not clear |
Shannon D Donofry, Claire E O'Hanlo. Measuring Cognition in Clinical Trials in Parkinson's Disease, Dementia with Lewy Bodies, and Related Disorders: Roundtable Proceedings and Roadmap for Research. Rand health quarterly. vol 11. issue 4. 2024-09-30. PMID:39346105. |
emerging research suggests that parkinson's disease (pd) and dementia with lewy bodies (dlb) share underlying pathology and may represent a single, biologically defined disease spectrum. |
2024-09-30 |
2024-10-02 |
Not clear |
Lucy L Gibson, Christoph Mueller, Robert Stewart, Dag Aarslan. Characteristics associated with progression to probable dementia with Lewy bodies in a cohort with very late-onset psychosis. Psychological medicine. 2024-09-26. PMID:39324394. |
very late-onset psychosis (vlop) is associated with higher rates of dementia but the proportion who develop dementia with lewy bodies (dlb) is unknown. |
2024-09-26 |
2024-09-28 |
Not clear |
Lucy L Gibson, Christoph Mueller, Robert Stewart, Dag Aarslan. Characteristics associated with progression to probable dementia with Lewy bodies in a cohort with very late-onset psychosis. Psychological medicine. 2024-09-26. PMID:39324394. |
we aimed to identify individuals with vlop who develop dementia and dlb and characterize the risk factors for progression. |
2024-09-26 |
2024-09-28 |
Not clear |
Kazuki Miyaue, Hiroki Ison. A Case Report of Probable Dementia With Lewy Bodies Diagnosed Through Repeated Episodes of Depressed Consciousness. Cureus. vol 16. issue 8. 2024-09-24. PMID:39310588. |
this case report details the diagnostic challenges of an 84-year-old male with unrecognized dementia with lewy bodies (dlb) who presented to the emergency department (ed) with episodes of unresponsiveness and depressed consciousness. |
2024-09-24 |
2024-09-26 |
Not clear |
Kazuki Miyaue, Hiroki Ison. A Case Report of Probable Dementia With Lewy Bodies Diagnosed Through Repeated Episodes of Depressed Consciousness. Cureus. vol 16. issue 8. 2024-09-24. PMID:39310588. |
this case underscores the importance of considering dlb in patients with unexplained recurrent depressed consciousness and highlights the importance of clarifying the etiologies of dementia. |
2024-09-24 |
2024-09-26 |
Not clear |
Shunji Toya, Mamoru Hashimoto, Yuta Manabe, Hajime Yamakage, Manabu Iked. Factors Associated with Increased Burden of Caregivers of People with Dementia with Lewy Bodies. Geriatrics (Basel, Switzerland). vol 9. issue 5. 2024-09-23. PMID:39311240. |
the burden of caregivers of people with dementia with lewy bodies (dlb) is high; however, factors related to their caregiving burden are not fully clarified. |
2024-09-23 |
2024-09-26 |
Not clear |
Miho Ota, Hiroyuki Maki, Yuji Takahashi, Yoko Shigemoto, Yukio Kimura, Hiroshi Matsuda, Noriko Sat. Relationships between neuroimaging biomarkers and glymphatic-system activity in dementia with Lewy bodies. Neuroscience letters. vol 842. 2024-09-23. PMID:39307177. |
alpha-synuclein deposits in the brain have been suspected to cause parkinson's disease and dementia with lewy bodies (dlb). |
2024-09-23 |
2024-09-26 |
human |
Estelle Schueller, Iris Grgurina, Brigitte Cosquer, Elodie Panzer, Noémie Penaud, Anne Pereira, Aline Stéphan, Karine Merienne, Jean-Christophe Cassel, Chantal Mathis, Frédéric Blanc, Olivier Bousiges, Anne-Laurence Boutillie. A novel mouse model reproducing frontal alterations related to the prodromal stage of dementia with LEWY bodies. Neurobiology of disease. 2024-09-22. PMID:39307398. |
dementia with lewy bodies (dlb) is the second most common age-related neurocognitive pathology after alzheimer's disease. |
2024-09-22 |
2024-09-26 |
mouse |
Carmelo Luca Smeralda, Siddhartha Pandit, Sonia Turrini, Julianne Reilly, Annalisa Palmisano, Giulia Sprugnoli, Harald Hampel, Alberto Benussi, Barbara Borroni, Daniel Press, Alexander Rotenberg, Georges El Fakhri, Giacomo Koch, Simone Rossi, Emiliano Santarnecch. The role of parvalbumin interneuron dysfunction across neurodegenerative dementias. Ageing research reviews. 2024-09-21. PMID:39306248. |
recent evidence indicates that pv+ cells are also impaired in frontotemporal dementia (ftd) and dementia with lewy bodies (dlb). |
2024-09-21 |
2024-09-24 |
Not clear |
Ankit Srivastava, Qinlu Wang, Christina D Orrù, Manel Fernandez, Yaroslau Compta, Bernardino Ghetti, Gianluigi Zanusso, Wen-Quan Zou, Byron Caughey, Catherine A A Beauchemi. Enhanced quantitation of pathological α-synuclein in patient biospecimens by RT-QuIC seed amplification assays. PLoS pathogens. vol 20. issue 9. 2024-09-20. PMID:39302978. |
disease associated pathological aggregates of alpha-synuclein (αsynd) exhibit prion-like spreading in synucleinopathies such as parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2024-09-20 |
2024-09-23 |
Not clear |
Jinghuan Gan, Ziming Xu, Zhichao Chen, Shuai Liu, Hao Lu, Yajie Wang, Hao Wu, Zhihong Shi, Huijun Chen, Yong J. Blood-brain barrier breakdown in dementia with Lewy bodies. Fluids and barriers of the CNS. vol 21. issue 1. 2024-09-18. PMID:39289698. |
however, a relation between bbb dysfunction and dementia with lewy bodies (dlb) has yet to be systematically investigated. |
2024-09-18 |
2024-09-20 |
Not clear |
Anna Rennie, Urban Ekman, Sara Shams, Lina Rydén, Jessica Samuelsson, Anna Zettergren, Silke Kern, Ketil Oppedal, Frédéric Blanc, Jakub Hort, Sara Garcia-Ptacek, Angelo Antonini, Afina W Lemstra, Alessandro Padovani, Milica Gregoric Kramberger, Irena Rektorová, Zuzana Walker, Jón Snædal, Matteo Pardini, John-Paul Taylor, Laura Bonanni, Tobias Granberg, Dag Aarsland, Ingmar Skoog, Lars-Olof Wahlund, Miia Kivipelto, Eric Westman, Daniel Ferreir. Cerebrovascular and Alzheimer's disease biomarkers in dementia with Lewy bodies and other dementias. Brain communications. vol 6. issue 5. 2024-09-18. PMID:39291165. |
we gathered a multi-cohort dataset of 4549 participants (dementia with lewy bodies = 331, cognitively unimpaired = 1505, mild cognitive impairment = 1489, alzheimer's disease = 708, mixed dementia = 268, vascular dementia = 148, parkinson's disease with dementia = 120) from the memclin study, karolinska imaging in dementia study, gothenburg h70 birth cohort studies and the european dlb consortium. |
2024-09-18 |
2024-09-20 |
human |
Tomoyuki Miyamoto, Itsuo Nakajima, Takuo Arikawa, Masayuki Miyamot. Bowel movement frequency and difficult defecation using constipation assessment scale in patients with isolated REM sleep behavior disorder. Clinical parkinsonism & related disorders. vol 11. 2024-09-17. PMID:39286572. |
this study evaluated constipation, including reduced bowel movement frequency and difficult defecation, in patients with isolated rapid eye movement sleep behavior disorder (irbd), which is prodromal parkinson's disease (pd) or dementia with lewy bodies (dlb) in middle-aged and older adults. |
2024-09-17 |
2024-09-19 |
Not clear |
Antoine Freuchet, Anaëlle Pinçon, Alessandro Sette, Cecilia S Lindestam Arleham. Inflammation and heterogeneity in synucleinopathies. Frontiers in immunology. vol 15. 2024-09-16. PMID:39281666. |
synucleinopathies, including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa), present complex challenges in understanding their onset and progression. |
2024-09-16 |
2024-09-19 |
Not clear |
Thomas G Beach, Geidy E Serrano, Nan Zhang, Erika D Driver-Dunckley, Lucia I Sue, Holly A Shill, Shyamal H Mehta, Christine Belden, Cecilia Tremblay, Parichita Choudhury, Alireza Atri, Charles H Adle. Clinicopathological Heterogeneity of Lewy Body Diseases: The Profound Influence of Comorbid Alzheimer's Disease. medRxiv : the preprint server for health sciences. 2024-09-16. PMID:39281742. |
in recent years, proposals have been advanced to redefine or reclassify lewy body disorders by merging the long-established entities of parkinson's disease (pd), parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb). |
2024-09-16 |
2024-09-19 |
human |
Anna E Goodheart, Stephen N Gompert. The association between cigarette smoking and dementia with Lewy bodies. Parkinsonism & related disorders. vol 128. 2024-09-14. PMID:39276722. |
as dementia with lewy bodies (dlb) and pd share core neuropathologic features, we set out to examine the relationship between smoking and dlb. |
2024-09-14 |
2024-09-18 |
Not clear |
Yoshihiro Chadani, Ryoko Fujito, Naohiro Kimura, Ryo Kawai, Tetsuo Kashibayashi, Ryuichi Takahashi, Hideki Kanemoto, Kazunari Ishii, Kenji Tagai, Shunichiro Shinagawa, Manabu Ikeda, Hiroaki Kazu. Neural basis of false recognition in Alzheimer's disease and dementia with lewy bodies. Scientific reports. vol 14. issue 1. 2024-09-12. PMID:39266605. |
in dementia with lewy bodies (dlb), no such association has been reported. |
2024-09-12 |
2024-09-15 |
Not clear |
Giuseppe Mario Bentivenga, Simone Baiardi, Andrea Mastrangelo, Edoardo Ruggeri, Angela Mammana, Alice Ticca, Marcello Rossi, Sabina Capellari, Piero Parch. Clinical, neuropathological, and molecular characteristics of rapidly progressive dementia with Lewy bodies: a distinct clinicopathological entity? Alzheimer's research & therapy. vol 16. issue 1. 2024-09-11. PMID:39256877. |
the term rapidly progressive dementia (rpd) with lewy bodies (rpdlb) is used for dlb patients who develop a rapidly progressive neurological syndrome and have reduced survival. |
2024-09-11 |
2024-09-13 |
Not clear |
Yuta Inagawa, Shoya Inagawa, Naoto Takenoshita, Ryo Yamamoto, Akito Tsugawa, Mana Yoshimura, Kazuhiro Saito, Soichiro Shimiz. Utility of neuromelanin-sensitive MRI in the diagnosis of dementia with Lewy bodies. PloS one. vol 19. issue 9. 2024-09-09. PMID:39250493. |
dementia with lewy bodies (dlb) is recognized as the second most common cause of degenerative dementia in older people with alzheimer's disease (ad), and distinguishing between these 2 diseases may be challenging in clinical practice. |
2024-09-09 |
2024-09-13 |
Not clear |