| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hao Wu, Zhen Sun, Jinghuan Gan, Chen Wen, Zhihong Shi, Shuai Liu, Yong J. Efficacy of cholinesterase inhibitors treatment in dementia with Lewy bodies: A 3-year follow-up 'real world' study. Journal of Alzheimer's disease : JAD. 2025-04-22. PMID:40259559. |
backgrounddementia with lewy bodies (dlb) is the second most common dementia after alzheimer's disease. |
2025-04-22 |
2025-04-24 |
Not clear |
| Hao Wu, Zhen Sun, Jinghuan Gan, Chen Wen, Zhihong Shi, Shuai Liu, Yong J. Efficacy of cholinesterase inhibitors treatment in dementia with Lewy bodies: A 3-year follow-up 'real world' study. Journal of Alzheimer's disease : JAD. 2025-04-22. PMID:40259559. |
however, evidence of cholinergic deficits suggests that enhancing central cholinergic function may be a viable therapeutic approach.objectiveto assess cognitive changes in dlb patients treated with cholinesterase inhibitors (cheis) in a real-world setting.methodsthis retrospective study in a prospective database analyzed data from three dementia clinics between may 2012 and december 2022. |
2025-04-22 |
2025-04-24 |
Not clear |
| Claudio Zaccone, Paraskevi Krashia, Marcello D'Ameli. A spit for a tip in dementia diagnosis: Evidence from saliva for dementia with Lewy bodies. Journal of Alzheimer's disease : JAD. 2025-04-21. PMID:40255030. |
being the second most-frequent type of age-related neurodegenerative dementia, dementia with lewy bodies (dlb) is currently exerting a huge burden on the healthcare system. |
2025-04-21 |
2025-04-23 |
Not clear |
| Asad Abdi, Milad Alipour, Milad Ghanikolahloo, Amin Magsudy, Fatemeh HojjatiPour, Ali Gholamrezanezhad, Mehran Ilaghi, Mehran Anjomrooz, Fatemeh Sayehmiri, Ramtin Hajibeygi, Mobina Fathi, Reza Assadsangab. Comparative analysis of white matter signal alterations in dementia with Lewy bodies and Alzheimer's disease: a systematic review and meta-analysis. Frontiers in radiology. vol 5. 2025-04-21. PMID:40256257. |
lewy body diseases (lbd) include neurodegenerative diseases such as parkinson's disease (pd), dementia with lewy bodies (dlb), and parkinson's disease dementia (pdd). |
2025-04-21 |
2025-04-23 |
Not clear |
| Asad Abdi, Milad Alipour, Milad Ghanikolahloo, Amin Magsudy, Fatemeh HojjatiPour, Ali Gholamrezanezhad, Mehran Ilaghi, Mehran Anjomrooz, Fatemeh Sayehmiri, Ramtin Hajibeygi, Mobina Fathi, Reza Assadsangab. Comparative analysis of white matter signal alterations in dementia with Lewy bodies and Alzheimer's disease: a systematic review and meta-analysis. Frontiers in radiology. vol 5. 2025-04-21. PMID:40256257. |
white matter hyperintensities (wmh) are associated with dementia risk and changes in both dlb and ad. |
2025-04-21 |
2025-04-23 |
Not clear |
| Charlotte F Brzozowski, Harshita Challa, Nolwazi Z Gcwensa, Dominic Hall, Douglas Nabert, Nicole Chambers, Ignacio Gallardo, Michael Millet, Laura Volpicelli-Daley, Mark S Moehl. Early A-synuclein aggregation decreases corticostriatal glutamate drive and synapse density. Neurobiology of disease. 2025-04-18. PMID:40250719. |
neuronal inclusions of α-synuclein (α-syn) are pathological hallmarks of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2025-04-18 |
2025-04-21 |
mouse |
| Ryosuke Amagai, Ryunosuke Hosoi, Sakura Yoshioka, Taiki Maruyama, Takayuki Kawai, Soroku Yagihashi, Hitoshi Nukada, Ryuji Sakakibara, Ayako Okado-Matsumot. The potential of erythrocyte α-synuclein to differentiate dementia with Lewy bodies from Parkinson's and Alzheimer's diseases. Journal of biochemistry. 2025-04-16. PMID:40235217. |
dementia with lewy bodies (dlb) is the second most common neurodegenerative dementia after alzheimer's disease (ad). |
2025-04-16 |
2025-04-18 |
human |
| Anupam Raina, Wen Wang, Jose Carlos Gonzalez, Xiaohui Yan, Linda Overstreet-Wadiche, Jacques I Wadiche, Chun-Li Zhang, Shu G Che. Distinct alpha-synuclein strains derived from Parkinson's disease patient tissues trigger differential inclusion pathology in a novel biosensor cell model. bioRxiv : the preprint server for biology. 2025-04-16. PMID:40236210. |
α-synuclein (αsyn) can misfold and aggregate to form fibrillar ß-sheet-rich aggregates ("strains") that are phosphorylated (p-αsyn) and deposited into intracellular inclusions in the brain, the pathological hallmark of synucleinopathies including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2025-04-16 |
2025-04-18 |
Not clear |
| Alexis Dema. Alice in Wonderland Syndrome in dementia with Lewy bodies: a case report exploring visual cognition dysfunction. Frontiers in neurology. vol 16. 2025-04-12. PMID:40212614. |
its occurrence in neurodegenerative conditions, particularly in dementia with lewy bodies (dlb), remains exceedingly rare. |
2025-04-12 |
2025-04-14 |
Not clear |
| Simon Kang Seng Ting, Seyed Ehsan Saffari, Shahul Hameed, Wei Shan Li, Jinesh Mukesh Shah, Hui Jin Chiew, Kok Pin Ng, Adeline Sl N. Clinical characteristics of pathological confirmed DLB without parkinsonism. Journal of the neurological sciences. vol 472. 2025-04-09. PMID:40203665. |
the misdiagnosis rate of dementia with lewy bodies (dlb) remains high. |
2025-04-09 |
2025-04-12 |
Not clear |
| Laura Arnaldo, Jorge Mena, Mònica Serradell, Carles Gaig, David Adamuz, Dolores Vilas, Daniela Samaniego, Lourdes Ispierto, Angelica Montini, Gerard Mayà, Ramiro Álvarez, Pau Pastor, Alex Iranzo, Katrin Beye. Platelet miRNAs as early biomarkers for progression of idiopathic REM sleep behavior disorder to a synucleinopathy. Scientific reports. vol 15. issue 1. 2025-04-09. PMID:40204936. |
individuals diagnosed with isolated rem sleep behavior disorder (irbd) have a high risk of developing lewy body disorders (lbd), mainly parkinson's disease (pd) or dementia with lewy bodies (dlb). |
2025-04-09 |
2025-04-12 |
Not clear |
| Karl Brown, Andrew Shutes-David, Sarah Payne, Adrienne Jankowski, Katie Wilson, Edmund Seto, Debby W Tsuan. The relationship between age and physical activity as objectively measured by accelerometers in older adults with and without dementia. Digital health. vol 11. 2025-04-07. PMID:40190339. |
this study sought to investigate differences in physical activity and activity fragmentation between older adults with and without dementia and between older adults with dementia with lewy bodies (dlb) and older adults with alzheimer's disease (ad). |
2025-04-07 |
2025-04-09 |
Not clear |
| Anna Planas-Ballvé, José Rios, Lourdes Ispierto, Mireia Gea, Laia Grau, Marta Jiménez, Cynthia Cáceres, Sílvia Martínez, Katrin Beyer, Ramiro Álvarez, Pau Pastor, Dolores Vila. Key motor and non-motor features in early dementia with Lewy bodies. Frontiers in neurology. vol 16. 2025-04-04. PMID:40183012. |
the objective of our study was to characterize early-stage dementia with lewy bodies (dlb) focusing on motor and non-motor symptoms. |
2025-04-04 |
2025-04-06 |
Not clear |
| Manikandan Samidurai, Karthick Chennakesavan, Souvarish Sarkar, Emir Malovic, Hai M Nguyen, Latika Singh, Anil Kumar, Alyssa Ealy, Chelva Janarthanam, Bharathi Niveditha Palanisamy, Naveen Kondru, Gary Zenitsky, Huajun Jin, Vellareddy Anantharam, Anumantha Kanthasamy, Hui Zhang, Heike Wulff, Arthi Kanthasam. KCa3.1 Contributes to Neuroinflammation and Nigral Dopaminergic Neurodegeneration in Experimental models of Parkinson's Disease. bioRxiv : the preprint server for biology. 2025-04-01. PMID:40166152. |
herein, we show that kca3.1, a calcium-activated potassium channel, is robustly upregulated within microglia in multiple preclinical models of pd and, most importantly, in human pd and dementia with lewy bodies (dlb) brains. |
2025-04-01 |
2025-04-03 |
mouse |
| Kazuhiro Takeda, Hiroshige Fujishiro, Youta Torii, Hirotaka Sekiguchi, Shusei Arafuka, Chikako Habuchi, Ayako Miwa, Norio Ozaki, Mari Yoshida, Shuji Iritani, Yasushi Iwasaki, Masashi Iked. Validation of the neuropathological criteria of the fourth Consortium on dementia with Lewy Bodies in autopsy cases from psychiatric hospitals. Psychiatry and clinical neurosciences. 2025-03-31. PMID:40162542. |
the pathological criteria from the fourth consortium on dementia with lewy bodies (dlb) in psychiatric cohorts has not been validated. |
2025-03-31 |
2025-04-03 |
Not clear |
| Jennifer Zitser, Sven Forner, Katherine Wong, Jin Chengshi, John Neuhaus, Jennifer Martindale, Ben J Raudabaugh, Kendra Benisano, Kelly Goodman-O'Leary, Stacy Metcalf, Mee-Ohk Kim, Marwa Hakimi, Isabelle E Allen, Bruce L Miller, Howard J Rosen, Katherine P Rankin, Michael D Geschwin. Neuropsychiatric symptoms in sporadic Creutzfeldt-Jakob disease. Brain : a journal of neurology. 2025-03-28. PMID:40152909. |
the objective of our study was to assess prospectively the neuropsychiatric features in scjd (and their impact on caregivers) and compare them with five other neurodegenerative diseases: alzheimer's disease (ad), dementia with lewy bodies (dlb), progressive supranuclear palsy (psp), behavioral variant frontotemporal dementia (bvftd) and semantic variant primary progressive aphasia (svppa). |
2025-03-28 |
2025-03-30 |
human |
| Yasuharu Ishihara, Mai Ando, Yasuaki Goto, Sadaharu Kotani, Naoto Watanabe, Yosuke Nakatani, Satoko Ishii, Norimasa Miyamoto, Yuji Mano, Yukio Ishikaw. A novel selective phosphodiesterase 9 inhibitor, irsenontrine (E2027), enhances GluA1 phosphorylation in neurons and improves learning and memory via cyclic GMP elevation. Neuropharmacology. 2025-03-27. PMID:40147639. |
several studies have found that the no/cgmp/pkg pathway is downregulated in patients with alzheimer's disease (ad) or dementia with lewy bodies (dlb) and in older individuals. |
2025-03-27 |
2025-03-30 |
rat |
| Laura M Farr, Naomi Thorpe, Ethel M Brinda, Naser Albalushi, Mohammad Sohail, Anto P Rajkuma. Systematic Review of Differentially Abundant Proteins in People with Lewy Body Dementia. Acta neuropsychiatrica. 2025-03-27. PMID:40143552. |
dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd) are collectively called as lewy body dementia (lbd). |
2025-03-27 |
2025-03-30 |
Not clear |
| Jack Anderson, Nicholas K H Chiu, Jonathon E Pye, Maria Comas-Soberats, Aaron Lam, Ronald R Grunstein, Simon J G Lewis, Elie Mata. Rest-Activity Disturbances Correlate with Core Features in Dementia with Lewy Bodies. Movement disorders clinical practice. 2025-03-25. PMID:40130686. |
sleep-wake disturbances are a clinically important and poorly studied feature of dementia with lewy bodies (dlb) due to the challenges of in-laboratory polysomnography in this population. |
2025-03-25 |
2025-03-27 |
Not clear |
| Solji G Choi, Tyler R Tittle, Raj R Barot, Dakota J Betts, Johnie J Gallagher, Jeffrey H Kordower, Yaping Chu, Bryan A Killinge. Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson's disease. Acta neuropathologica communications. vol 13. issue 1. 2025-03-24. PMID:40122840. |
synucleinopathies such as parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa) are neurodegenerative diseases with shared clinical and pathological features. |
2025-03-24 |
2025-03-26 |
Not clear |