All Relations between Cognitive Dysfunction and hippocampus

Publication Sentence Publish Date Extraction Date Species
Liang Chen, Zhifeng Yue, Ziyu Liu, Huaqin Liu, Jin Zhang, Fengjiao Zhang, Tao Hu, Jianfeng F. The Impact of Nrf2 Knockout on the Neuroprotective Effects of Dexmedetomidine in a Mice Model of Cognitive Impairment. Behavioural brain research. 2024-05-01. PMID:38692357. our research findings suggest that dex enhances the expression of nqo1, ho-1, psd95, and syp proteins in hippocampal tissue, inhibits microglial proliferation, reduces pro-inflammatory cytokines il-1β and tnf-ɑ, increases anti-inflammatory cytokine il-10, and improves dendritic spine density, thereby alleviating cognitive dysfunction induced by lps. 2024-05-01 2024-05-04 mouse
Saurabh Tiwari, Phoolmala, Shweta Goyal, Ranjeet Kumar Yadav, Rajnish Kumar Chaturved. Bisphenol-F and Bisphenol-S (BPF and BPS) Impair the Stemness of Neural Stem Cells and Neuronal Fate Decision in the Hippocampus Leading to Cognitive Dysfunctions. Molecular neurobiology. 2024-04-18. PMID:38635025. bisphenol-f and bisphenol-s (bpf and bps) impair the stemness of neural stem cells and neuronal fate decision in the hippocampus leading to cognitive dysfunctions. 2024-04-18 2024-04-20 Not clear
Lihua Wang, Mingjie Li, Bing Liu, Ruihan Zheng, Xinyi Zhang, Shuoyi Y. miR-30a-5p mediates ferroptosis of hippocampal neurons in chronic cerebral hypoperfusion-induced cognitive dysfunction by modulating the SIRT1/NRF2 pathway. Brain research bulletin. 2024-04-18. PMID:38636610. mir-30a-5p mediates ferroptosis of hippocampal neurons in chronic cerebral hypoperfusion-induced cognitive dysfunction by modulating the sirt1/nrf2 pathway. 2024-04-18 2024-04-21 Not clear
Ji-Yong Liu, Wen-Li Zhang, Jun Liao, Li-Juan Hu, Guo-Zuo Wang, Jin-Wen Ge, Zhi-Gang Me. [Effect of Naotaifang on microglial polarization and glial scar following cerebral ischemia reperfusion injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 4. 2024-04-15. PMID:38621906. compared with the sham, model 7 d and model 14 d groups showed cerebral infarction of different degrees, severe pathological injury of cerebral cortex and hippocampus, neurological impairment, reduced spatial learning and memory, cognitive dysfunction, severe anxiety, astrocyte hyperplasia, thickening penumbra glial scar, and up-regulated protein levels of il-1β, il-6, gfap, neurocan, phosphacan, cd206, and arg-1(p<0.01). 2024-04-15 2024-04-18 rat
Ming Wang, Binyuan Xu, Yangmei Xie, Ge Yao, Yinghui Che. Mir155hg Accelerates Hippocampal Neuron Injury in Convulsive Status Epilepticus by Inhibiting Microglial Phagocytosis. Neurochemical research. 2024-03-30. PMID:38555337. convulsive status epilepticus (cse) is a common critical neurological condition that can lead to irreversible hippocampal neuron damage and cognitive dysfunction. 2024-03-30 2024-04-02 rat
Evelini Plácido, David J Koss, Tiago Fleming Outeiro, Patricia S Brocard. Altered hippocampal doublecortin expression in Parkinson's disease. Journal of neurochemistry. 2024-03-14. PMID:38485468. in summary, we provide evidence supporting that the process of hippocampal adult neurogenesis is likely to be compromised in pd patients before cognitive dysfunction, shedding light on potential mechanisms contributing to the neuropsychiatric symptoms observed in affected individuals. 2024-03-14 2024-03-17 human
Jianxiong Gui, Mingdan Xie, Lingman Wang, Bing Tian, Benke Liu, Hengsheng Chen, Li Cheng, Dishu Huang, Ziyao Han, Xiaoyue Yang, Jie Liu, Li Jian. Protective effects of docosahexaenoic acid supplementation on cognitive dysfunction and hippocampal synaptic plasticity impairment induced by early postnatal PM2.5 exposure in young rats. Naunyn-Schmiedeberg's archives of pharmacology. 2024-03-09. PMID:38459987. protective effects of docosahexaenoic acid supplementation on cognitive dysfunction and hippocampal synaptic plasticity impairment induced by early postnatal pm2.5 exposure in young rats. 2024-03-09 2024-03-12 rat
Xueqin Wang, Shuang Wang, Yanhui Cu. Protective effects of the salt Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 48. issue 12. 2024-03-06. PMID:38448372. this study aims to investigate the expression of sik in the hippocampus of septic mice, and to evaluate the role and mechanism of the sik inhibitor hg-9-91-01 in sepsis-associated cognitive dysfunction. 2024-03-06 2024-03-09 mouse
Wenjing Yang, Chao Chen, Xiaolong Jiang, Yining Zhao, Junyang Wang, Qianqian Zhang, Jingyuan Zhang, Yan Feng, Shufang Cu. CACNA1B protects naked mole-rat hippocampal neuron from apoptosis via altering the subcellular localization of Nrf2 after Cell biology international. 2024-02-23. PMID:38389270. cacna1b protects naked mole-rat hippocampal neuron from apoptosis via altering the subcellular localization of nrf2 after although radiotherapy is the most effective treatment modality for brain tumors, it always injures the central nervous system, leading to potential sequelae such as cognitive dysfunction. 2024-02-23 2024-02-25 rat
Yixin Zhang, Xuan Liu, Ying Yang, Yihao Zhang, Qiang He, Feiyu Xu, Xinjuan Jin, Junqi Gao, Yuan Yao, Dexin Yu, Bernhard Hommel, Xingxing Zhu, Kangcheng Wang, Wenxin Zhan. Revealing complexity: Segmentation of hippocampal subfields in adolescents with major depressive disorder reveals specific links to cognitive dysfunctions. European psychiatry : the journal of the Association of European Psychiatrists. 2024-02-23. PMID:38389334. revealing complexity: segmentation of hippocampal subfields in adolescents with major depressive disorder reveals specific links to cognitive dysfunctions. 2024-02-23 2024-02-25 Not clear
Yuka Kusui, Naotaka Izuo, Reika Tokuhara, Takashi Asano, Atsumi Nitt. Neuronal activation of nucleus accumbens by local methamphetamine administration induces cognitive impairment through microglial inflammation in mice. Journal of pharmacological sciences. vol 154. issue 3. 2024-02-23. PMID:38395513. mice with meth (nac) exhibited cognitive dysfunction in behavioral analyses and decreased long-term potentiation in the hippocampus, with nac activation confirmed by expression of fosb, a neuronal activity marker. 2024-02-23 2024-02-26 mouse
Jie Wan, Linhui Ma, Xinhao Jiao, Wei Dong, Jiatao Lin, Yongkang Qiu, Weifeng Wu, Qiang Liu, Chen Chen, He Huang, Shuai Li, Hui Zheng, Yuqing W. Impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by BDNF downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine. CNS neuroscience & therapeutics. vol 30. issue 2. 2024-02-09. PMID:38332635. impaired synaptic plasticity and decreased excitability of hippocampal glutamatergic neurons mediated by bdnf downregulation contribute to cognitive dysfunction in mice induced by repeated neonatal exposure to ketamine. 2024-02-09 2024-02-11 mouse
Rui Liu, GuanZhong Gong, KangNing Meng, ShanShan Du, Yong Yi. Hippocampal sparing in whole-brain radiotherapy for brain metastases: controversy, technology and the future. Frontiers in oncology. vol 14. 2024-02-08. PMID:38327749. the development of cognitive dysfunction is closely related to hippocampal injury, but standardized criteria for predicting hippocampal injury and dose limits for hippocampal protection have not yet been developed. 2024-02-08 2024-02-10 Not clear
Rui Liu, GuanZhong Gong, KangNing Meng, ShanShan Du, Yong Yi. Hippocampal sparing in whole-brain radiotherapy for brain metastases: controversy, technology and the future. Frontiers in oncology. vol 14. 2024-02-08. PMID:38327749. in the future, the application of new techniques and methods can improve the consistency of hippocampal dose limit determination and the prediction of the occurrence of cognitive dysfunction in wbrt patients, avoiding the occurrence of cognitive dysfunction in patients and thus benefiting more patients with bms. 2024-02-08 2024-02-10 Not clear
Yingsi Cao, Wenjing Zhao, Yanqi Zhong, Xiaofan Jiang, Huiya Mei, Yuanjin Chang, Dongqin Wu, JianRui Dou, Emely Vasquez, Xian Shi, Jiatao Yang, Zhongtang Jia, Xiaochao Tan, Qian Li, Yuying Dong, Ruijin Xie, Ju Gao, Yu Wu, Yueying Li. Effects of chronic low-level lead (Pb) exposure on cognitive function and hippocampal neuronal ferroptosis: An integrative approach using bioinformatics analysis, machine learning, and experimental validation. The Science of the total environment. 2024-02-01. PMID:38301787. furthermore, our in vitro and in vivo experimental results strongly suggest that lead exposure may precipitate cognitive dysfunction and induce hippocampal neuronal ferroptosis. 2024-02-01 2024-02-04 Not clear
Jianbin Zhu, Haixiang Wei, Minying Jiang, Ting Li, Ruizhu Wu, Hualiang Che. Effect of Dexmedetomidine on Apoptosis and Early Cognitive Dysfunction in Rats Following Propofol Anesthesia. Alternative therapies in health and medicine. 2024-01-30. PMID:38290461. to address the intricate interplay between surgical anesthesia, hippocampal apoptosis, and early cognitive dysfunction in rats, this study delves into the impact of dexmedetomidine (dex). 2024-01-30 2024-02-02 rat
Rui Sun, Kedi Xi, Shengjun Ji, Xing Song, Dan Xi, Wenming Yin, Yingjie Shao, Wendong Gu, Jingting Jian. TDP-43 was Involved in Radiation-induced Neuronal Damage and May Not Through the BDNF/TrkB Pathway. Radiation research. 2024-01-18. PMID:38235539. tdp-43 is known to be associated with hippocampal degeneration and cognitive dysfunction, in this study we wanted to know if it also had an effect on radiation-induced hippocampus damage. 2024-01-18 2024-01-20 rat
Rui Sun, Kedi Xi, Shengjun Ji, Xing Song, Dan Xi, Wenming Yin, Yingjie Shao, Wendong Gu, Jingting Jian. TDP-43 was Involved in Radiation-induced Neuronal Damage and May Not Through the BDNF/TrkB Pathway. Radiation research. 2024-01-18. PMID:38235539. at first, we found the expression of tdp-43 and p-tdp-43 was increased in the hippocampus of rats with radiation-induced cognitive dysfunction. 2024-01-18 2024-01-20 rat
Lan Wu, Xiang-Jian Meng, Tian-Bao Xu, Xian-Cui Zhang, Yong Zhou, Zhu-Feng Tong, Jing-Han Jian. Berberine attenuates cognitive dysfunction and hippocampal apoptosis in rats with prediabetes. Chemical biology & drug design. vol 103. issue 1. 2024-01-17. PMID:38230770. berberine attenuates cognitive dysfunction and hippocampal apoptosis in rats with prediabetes. 2024-01-17 2024-01-19 human
Peiyu Shuai, Zhihong Hu, Wei Li, Guoliang You, Zhiye Liu, Niandong Zhen. The protective role of circ_0016760 downregulation against sevoflurane‑induced neurological impairment via modulating miR‑145 expression in aged rats. Acta neurobiologiae experimentalis. vol 83. issue 4. 2024-01-15. PMID:38224284. sevoflurane can produce toxicity to the hippocampal tissues of brain, leading to nerve damage, causing learning and cognitive dysfunction. 2024-01-15 2024-01-17 rat