| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Clarke, S Lee, V Eape. Pathogenetic model for Tourette syndrome delineates overlap with related neurodevelopmental disorders including Autism. Translational psychiatry. vol 2. 2013-03-01. PMID:22948383. |
in this review, we explore a previously unrecognised genetic link between ts and a competing series of trans-synaptic complexes (neurexins (nrxns), neuroligins (nlgns), leucine-rich repeat transmembrane proteins (lrrtms), leucine rich repeat neuronals (lrrns) and cerebellin precursor 2 (cbln2)) that links it with autism spectrum disorder through neurodevelopmental pathways. |
2013-03-01 |
2023-08-12 |
Not clear |
| Patrick L Bader, Mehrdad Faizi, Leo H Kim, Scott F Owen, Michael R Tadross, Ronald W Alfa, Glenna C L Bett, Richard W Tsien, Randall L Rasmusson, Mehrdad Shamlo. Mouse model of Timothy syndrome recapitulates triad of autistic traits. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 37. 2011-11-09. PMID:21878566. |
in some rare cases, such as timothy syndrome (ts), a specific mutation in a single gene can be sufficient to generate autism or asd in most patients, potentially offering insights into the etiology of autism in general. |
2011-11-09 |
2023-08-12 |
mouse |
| Nicholas Lange, Molly B Dubray, Jee Eun Lee, Michael P Froimowitz, Alyson Froehlich, Nagesh Adluru, Brad Wright, Caitlin Ravichandran, P Thomas Fletcher, Erin D Bigler, Andrew L Alexander, Janet E Lainhar. Atypical diffusion tensor hemispheric asymmetry in autism. Autism research : official journal of the International Society for Autism Research. vol 3. issue 6. 2011-05-06. PMID:21182212. |
we hypothesized that further study of white matter microstructure (wmm) in the superior temporal gyrus (stg) and temporal stem (ts), two brain regions in the temporal lobe containing circuitry central to language, emotion, and social cognition, would identify a useful combination of classification features and further understand autism neuropathology. |
2011-05-06 |
2023-08-12 |
Not clear |
| Masaya Segaw. [Walking abnormalities in children]. Brain and nerve = Shinkei kenkyu no shinpo. vol 62. issue 11. 2011-01-03. PMID:21068458. |
patients with infantile autism (ia), rett syndrome (rtt), or tourette syndrome (ts) show failure in the development of the first, second, or third epoch, respectively. |
2011-01-03 |
2023-08-12 |
Not clear |
| Ping Liao, Tuck Wah Soon. CaV1.2 channelopathies: from arrhythmias to autism, bipolar disorder, and immunodeficiency. Pflugers Archiv : European journal of physiology. vol 460. issue 2. 2010-09-13. PMID:19916019. |
ts patients also suffer from multi-organ dysfunction that includes neurological disorder such as autism and mental retardation reflecting the wide tissue distribution of cav1.2 channel. |
2010-09-13 |
2023-08-12 |
human |
| Senthil K Sundaram, Ahm M Huq, Benjamin J Wilson, Harry T Chugan. Tourette syndrome is associated with recurrent exonic copy number variants. Neurology. vol 74. issue 20. 2010-06-02. PMID:20427753. |
multiple rare copy number variants (cnvs) including genomic deletions and duplications play a prominent role in neurodevelopmental disorders such as mental retardation, autism, and schizophrenia, but have not been systematically studied in tourette syndrome (ts). |
2010-06-02 |
2023-08-12 |
Not clear |
| Eric Hollander, Suah Kim, Ashley Braun, Daphne Simeon, Joseph Zoha. Cross-cutting issues and future directions for the OCD spectrum. Psychiatry research. vol 170. issue 1. 2010-02-01. PMID:19811839. |
the disorders that were originally examined included ocd, obsessive-compulsive personality disorder (ocpd), tourette's syndrome (ts) and other tic disorders, sydenham's chorea, pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (pandas), trichotillomania (ttm), body dysmorphic disorder (bdd), autism, eating disorders, huntington's and parkinson's disease, impulse control disorders, as well as substance and behavioral addictions. |
2010-02-01 |
2023-08-12 |
Not clear |
| Hilde M Geurts, Raoul P P P Grasman, Sylvie Verté, Jaap Oosterlaan, Herbert Roeyers, Serena M van Kammen, Joseph A Sergean. Intra-individual variability in ADHD, autism spectrum disorders and Tourette's syndrome. Neuropsychologia. vol 46. issue 13. 2009-02-03. PMID:18619477. |
this study investigated the specificity of intra-individual variability (iiv) in 53 children with adhd by comparing them with 25 children with high functioning autism (hfa), 32 children with autism spectrum disorders (asd), who also were comorbid for adhd (asd+adhd), 21 children with tourette's syndrome (ts), and 85 typically developing controls (td). |
2009-02-03 |
2023-08-12 |
Not clear |
| Curtis F Barrett, Richard W Tsie. The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 6. 2008-03-31. PMID:18250309. |
inactivation of ca2+ channel activity is perturbed in a rare yet devastating disorder known as timothy syndrome (ts), whose features include autism or autism spectrum disorder along with severe cardiac arrhythmia and developmental abnormalities. |
2008-03-31 |
2023-08-12 |
Not clear |
| Curtis F Barrett, Richard W Tsie. The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 6. 2008-03-31. PMID:18250309. |
thus, the ts mutation offers a unique perspective on mechanisms of inactivation as well as a promising starting point for exploring the underlying pathophysiology of autism. |
2008-03-31 |
2023-08-12 |
Not clear |
| Jee Eun Lee, Erin D Bigler, Andrew L Alexander, Mariana Lazar, Molly B DuBray, Moo K Chung, Michael Johnson, Jubel Morgan, Judith N Miller, William M McMahon, Jeffrey Lu, Eun-Kee Jeong, Janet E Lainhar. Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autism. Neuroscience letters. vol 424. issue 2. 2008-01-04. PMID:17714869. |
recent mri studies have indicated that regions of the temporal lobe including the superior temporal gyrus (stg) and the temporal stem (ts) appear to be abnormal in autism. |
2008-01-04 |
2023-08-12 |
human |
| Jee Eun Lee, Erin D Bigler, Andrew L Alexander, Mariana Lazar, Molly B DuBray, Moo K Chung, Michael Johnson, Jubel Morgan, Judith N Miller, William M McMahon, Jeffrey Lu, Eun-Kee Jeong, Janet E Lainhar. Diffusion tensor imaging of white matter in the superior temporal gyrus and temporal stem in autism. Neuroscience letters. vol 424. issue 2. 2008-01-04. PMID:17714869. |
in this study, diffusion tensor imaging (dti) measurements of white matter in the stg and the ts were compared in 43 autism and 34 control subjects. |
2008-01-04 |
2023-08-12 |
human |
| Phoebe M Y Lynn, William Davie. The 39,XO mouse as a model for the neurobiology of Turner syndrome and sex-biased neuropsychiatric disorders. Behavioural brain research. vol 179. issue 2. 2007-06-05. PMID:17367875. |
moreover, ts subjects are at significantly increased risk of developing attention deficit hyperactivity disorder (adhd) and autism. |
2007-06-05 |
2023-08-12 |
mouse |
| Sylvie Verté, Hilde M Geurts, Herbert Roeyers, Jaap Oosterlaan, Joseph A Sergean. Executive functioning in children with autism and Tourette syndrome. Development and psychopathology. vol 17. issue 2. 2006-10-05. PMID:16761552. |
the main aims of this study were to investigate if children with high-functioning autism (hfa) and children with tourette syndrome (ts) can be differentiated in their executive functioning (ef) profile compared to normal controls (ncs) and compared to each other and to investigate whether children with hfa or children with ts and a comorbid group of children with both disorders are distinct conditions in terms of ef, four groups of children participated in this study: hfa, ts, comorbid hfa + ts, and a nc group. |
2006-10-05 |
2023-08-12 |
Not clear |
| Steve Septer, Edward S Thompson, Ann Willemsen-Dunla. Anesthesia concerns for children with tuberous sclerosis. AANA journal. vol 74. issue 3. 2006-07-20. PMID:16786916. |
the patient had several coexisting maladies from ts, including hypertension, autism, seizure disorder, cardiac rhabdomyomas, developmental delay, and bilateral polycystic renal disease. |
2006-07-20 |
2023-08-12 |
Not clear |
| Sylvie Verté, Hilde M Geurts, Herbert Roeyers, Jaap Oosterlaan, Joseph A Sergean. The relationship of working memory, inhibition, and response variability in child psychopathology. Journal of neuroscience methods. vol 151. issue 1. 2006-05-25. PMID:16427129. |
the aim of this study was to investigate the relationship between working memory and inhibition in children with attention deficit hyperactivity disorder (adhd), high-functioning autism (hfa), and tourette syndrome (ts), compared to normally developing children. |
2006-05-25 |
2023-08-12 |
Not clear |
| Eric Hollander, Evdokia Anagnostou, William Chaplin, Katherine Esposito, M Mehmet Haznedar, Elizabeth Licalzi, Stacey Wasserman, Latha Soorya, Monte Buchsbau. Striatal volume on magnetic resonance imaging and repetitive behaviors in autism. Biological psychiatry. vol 58. issue 3. 2005-09-19. PMID:15939406. |
the repetitive behaviors seen in autism phenotypically resemble those seen in obsessive-compulsive disorder (ocd) and tourette syndrome (ts), disorders in which structural and functional abnormalities of the basal ganglia (bg) are present and correspond to the severity of repetitive behaviors. |
2005-09-19 |
2023-08-12 |
Not clear |
| Ayla Humphrey, J Nicholas P Higgins, John R W Yates, Patrick F Bolto. Monozygotic twins with tuberous sclerosis discordant for the severity of developmental deficits. Neurology. vol 62. issue 5. 2004-12-27. PMID:15007135. |
the findings also raise questions about the mechanisms giving rise to autism in ts. |
2004-12-27 |
2023-08-12 |
Not clear |
| Christine M Temple, Patricia Martin Sanfilipp. Executive skills in Klinefelter's syndrome. Neuropsychologia. vol 41. issue 11. 2003-09-24. PMID:12849773. |
different patterns of disorder amongst these skills have been found in several developmental abnormalities including autism, attention deficit hyperactivity disorder (adhd) and turner's syndrome (ts). |
2003-09-24 |
2023-08-12 |
Not clear |
| J L Bradshaw, D M Sheppar. The neurodevelopmental frontostriatal disorders: evolutionary adaptiveness and anomalous lateralization. Brain and language. vol 73. issue 2. 2000-08-16. PMID:10856179. |
the frontostriatal system (dorsolateral prefrontal cortex, lateral orbitofrontal cortex, anterior cingulate, supplementary motor area, and associated basal-ganglia structures) is subject to a range of neurodevelopmental disorders: tourette's syndrome (ts), obsessive compulsive disorder (ocd), attention deficit hyperactivity disorder (adhd), schizophrenia (scz), autism, and probably depression. |
2000-08-16 |
2023-08-12 |
human |