| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrea G Ludolph, Patrick T Udvardi, Ulrike Schaz, Carolin Henes, Oliver Adolph, Henry U Weigt, Joerg M Fegert, Tobias M Boeckers, Karl J Föh. Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations. British journal of pharmacology. vol 160. issue 2. 2010-06-02. PMID:20423340. |
there is increasing evidence that not only the monoaminergic but also the glutamatergic system is involved in the pathophysiology of attention-deficit hyperactivity disorder (adhd). |
2010-06-02 |
2023-08-12 |
Not clear |
| V Jensen, J E Rinholm, T J Johansen, T Medin, J Storm-Mathisen, T Sagvolden, O Hvalby, L H Bergerse. N-methyl-D-aspartate receptor subunit dysfunction at hippocampal glutamatergic synapses in an animal model of attention-deficit/hyperactivity disorder. Neuroscience. vol 158. issue 1. 2009-04-09. PMID:18571865. |
the results indicate that functional impairments in glutamatergic synaptic transmission may be one of the underlying mechanisms leading to the abnormal behavior in shr, and possibly in human adhd. |
2009-04-09 |
2023-08-12 |
human |
| D Lule, A C Ludolph, A G Ludolp. Neurodevelopmental and neurodegenerative diseases - is there a pathophysiological link? Attention-deficit/hyperactivity disorder and amyotrophic lateral sclerosis as examples. Medical hypotheses. vol 70. issue 6. 2008-08-13. PMID:18158219. |
at the neurobiological level, there is evidence for hyperactivity in the glutamatergic system and a - potentially related - dopaminergic hypoactivity in adhd and als. |
2008-08-13 |
2023-08-12 |
Not clear |
| E Perlov, A Philipsen, B Hesslinger, M Buechert, J Ahrendts, B Feige, E Bubl, J Hennig, D Ebert, L Tebartz van Els. Reduced cingulate glutamate/glutamine-to-creatine ratios in adult patients with attention deficit/hyperactivity disorder -- a magnet resonance spectroscopy study. Journal of psychiatric research. vol 41. issue 11. 2007-11-30. PMID:17303167. |
however, there is also evidence for abnormalities in the glutamatergic system and recent theories focus on a disturbed interaction between the two systems as the essential pathogenetic mechanism of adhd. |
2007-11-30 |
2023-08-12 |
Not clear |
| Richard H Weisle. Emerging drugs for attention-deficit/hyperactivity disorder. Expert opinion on emerging drugs. vol 12. issue 3. 2007-09-27. PMID:17874970. |
potential therapies such as adrenergic receptor agonists, glutamatergic agents, gaba receptor antagonists and nicotine receptor agonists are being explored as future pharmacotherapies for adhd. |
2007-09-27 |
2023-08-12 |
Not clear |
| K M Dorval, K G Wigg, J Crosbie, R Tannock, J L Kennedy, A Ickowicz, T Pathare, M Malone, R Schachar, C L Bar. Association of the glutamate receptor subunit gene GRIN2B with attention-deficit/hyperactivity disorder. Genes, brain, and behavior. vol 6. issue 5. 2007-09-19. PMID:17010153. |
the glutamatergic signaling pathway represents an ideal candidate susceptibility system for attention-deficit/hyperactivity disorder (adhd). |
2007-09-19 |
2023-08-12 |
mouse |
| Normand J Carrey, Frank P MacMaster, Laura Gaudet, Matthias H Schmid. Striatal creatine and glutamate/glutamine in attention-deficit/hyperactivity disorder. Journal of child and adolescent psychopharmacology. vol 17. issue 1. 2007-05-30. PMID:17343550. |
the glutamatergic prefrontal-striatal pathway has been implicated previously in the neurobiology of attention-deficit/hyperactivity disorder (adhd). |
2007-05-30 |
2023-08-12 |
Not clear |
| Constance M Moore, Joseph Biederman, Janet Wozniak, Eric Mick, Megan Aleardi, Megan Wardrop, Meghan Dougherty, Terri Harpold, Paul Hammerness, Edin Randall, Perry F Rensha. Differences in brain chemistry in children and adolescents with attention deficit hyperactivity disorder with and without comorbid bipolar disorder: a proton magnetic resonance spectroscopy study. The American journal of psychiatry. vol 163. issue 2. 2006-03-20. PMID:16449488. |
the authors' goal was to investigate phosphatidylinositol and glutamatergic metabolism in the anterior cingulate cortex of children and adolescents with attention deficit hyperactivity disorder (adhd) alone, children with adhd plus bipolar disorder, and children with no axis i diagnosis. |
2006-03-20 |
2023-08-12 |
Not clear |
| Darko Turic, Kate Langley, Hywel Williams, Nadine Norton, Nigel M Williams, Valentina Moskvina, Marianne B Van den Bree, Michael J Owen, Anita Thapar, Michael C O'Donova. A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder. Biological psychiatry. vol 57. issue 11. 2005-07-29. PMID:15950021. |
the glutamatergic system, the major excitatory neurotransmitter system in the central nervous system (cns) has been proposed as contributing a possible role in the etiology of attention deficit hyperactivity disorder (adhd). |
2005-07-29 |
2023-08-12 |
Not clear |