| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Khuzaim Alzahrani, Alshrari A S, Mohd Imra. Unraveling the molecular mechanisms of ALS: a network biology and structural modeling approach of investigating the impact of C9orf72 mutations. Journal of biomolecular structure & dynamics. 2024-12-11. PMID:39659205. |
c9orf72 is a major genetic factor in amyotrophic lateral sclerosis (als), a neurodegenerative disorder affecting brain and spinal cord neurons, and comprehending its mutational impact is crucial for developing als therapies. |
2024-12-11 |
2024-12-13 |
Not clear |
| Hyo Jae Kim, Jae-Jun Ban, Junho Kang, Hye-Ryeong Im, Sun Hi Ko, Jung-Joon Sung, Sung-Hye Park, Jong-Eun Park, Seok-Jin Cho. Single-cell analysis reveals expanded CD8 Brain communications. vol 6. issue 6. 2024-12-11. PMID:39659975. |
single-cell analysis reveals expanded cd8 amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease that affects motor neurons in the brain and spinal cord. |
2024-12-11 |
2024-12-13 |
human |
| John F Tuddenham, Masashi Fujita, Anthony Khairallah, Claire Harbison, Xena E Flowers, Guillermo Coronas-Samano, Silas Maniatis, Aidan Daly, Julie A Schneider, Andrew F Teich, Jean Paul G Vonsattel, Peter A Sims, Wassim Elyaman, Elizabeth M Bradshaw, Hemali Phatnani, Neil Shneider, David A Bennett, Philip L De Jager, Serge Przedborski, Vilas Menon, Marta Ola. Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord. bioRxiv : the preprint server for biology. 2024-11-28. PMID:39605399. |
single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord. |
2024-11-28 |
2024-11-30 |
human |
| Banaja P Dash, Axel Freischmidt, Anika M Helferich, Albert C Ludolph, Peter M Andersen, Jochen H Weishaupt, Andreas Herman. Upregulated miR-10b-5p as a potential miRNA signature in amyotrophic lateral sclerosis patients. Frontiers in cellular neuroscience. vol 18. 2024-11-26. PMID:39588282. |
amyotrophic lateral sclerosis (als) is a fatal, adult-onset disease marked by a progressive degeneration of motor neurons (mns) present in the spinal cord, brain stem and motor cortex. |
2024-11-26 |
2024-11-28 |
Not clear |
| Zhongzhong Li, Yingzhen Zhang, Dongxiao Li, Xinyan Du, Lin Chen, Yansu Gu. Microglial upregulation of CD109 expression in spinal cord of amyotrophic lateral sclerosis mouse model and its role in modulating inflammation and TGFβ/SMAD pathway. Neuroscience. 2024-11-22. PMID:39577687. |
microglial upregulation of cd109 expression in spinal cord of amyotrophic lateral sclerosis mouse model and its role in modulating inflammation and tgfβ/smad pathway. |
2024-11-22 |
2024-11-25 |
mouse |
| Jamie F M Brannigan, Kishan Liyanage, Hugo Layard Horsfall, Luke Bashford, William Muirhead, Adam Fr. Brain-computer interfaces patient preferences: a systematic review. Journal of neural engineering. 2024-11-21. PMID:39569894. |
amyotrophic lateral sclerosis was the most represented clinical condition (n = 15 studies, 53.6%), followed by spinal cord injury (n = 13 studies, 46.4%). |
2024-11-21 |
2024-11-23 |
Not clear |
| Song Luo, Xiaorui Wang, Bo Ma, Dongliang Liu, Li Li, Lijin Wang, Ning Ding, Liangyu Zou, Jie Wang, Jialin Pan, Daoqian Sang, Huadong Zhou, Hongdang Qu, Yi Lu, Lijuan Yan. Therapeutic potential of Simvastatin in ALS: Enhanced axonal integrity and motor neuron survival through Apoa4 and Alb modulation. Biomolecules & biomedicine. 2024-11-21. PMID:39569650. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective death of motor neurons in the spinal cord, brainstem, and motor cortex. |
2024-11-21 |
2024-11-23 |
mouse |
| Meheroz H Rabadi, Kimberly A Russell, Chao X. Analysis of Mortality Causes and Locations in Veterans with ALS: A Decade Review. Medical science monitor : international medical journal of experimental and clinical research. vol 30. 2024-11-17. PMID:39550606. |
background amyotrophic lateral sclerosis (als) is a motor neuron disease that leads to rapid degeneration of nerves in the brain and spinal cord, with eventual loss of voluntary movements, including breathing. |
2024-11-17 |
2024-11-20 |
Not clear |
| M Khamaysa, M El Mendili, V Marchand, G Querin, P-F Prada. Quantitative spinal cord imaging: Early ALS diagnosis and monitoring of disease progression. Revue neurologique. 2024-11-15. PMID:39547910. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disorder characterized by the progressive degeneration of motor neurons in the cortex, brainstem, and spinal cord. |
2024-11-15 |
2024-11-18 |
Not clear |
| Carolina Sbarigia, Sophie Rome, Luciana Dini, Stefano Taccon. New perspectives of the role of skeletal muscle derived extracellular vesicles in the pathogenesis of amyotrophic lateral sclerosis: the 'dying back' hypothesis. Journal of extracellular biology. vol 3. issue 11. 2024-11-14. PMID:39534483. |
amyotrophic lateral sclerosis (als), is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord, and is characterized by muscle weakness, paralysis and ultimately, respiratory failure. |
2024-11-14 |
2024-11-17 |
Not clear |
| Neha Chopra, Spiro Menounos, Jaesung P Choi, Philip M Hansbro, Ashish D Diwan, Abhirup Da. Blood-Spinal Cord Barrier: Its Role in Spinal Disorders and Emerging Therapeutic Strategies. NeuroSci. vol 3. issue 1. 2024-11-01. PMID:39484675. |
here, we provide a descriptive analysis of the anatomy, current techniques to assess the impairment of bscb, associated risk factors and impact of spinal disorders such as spinal cord injury (sci), amyotrophic lateral sclerosis (als), peripheral nerve injury (pni), ischemia reperfusion injury (iri), degenerative cervical myelopathy (dcm), multiple sclerosis (ms), spinal cavernous malformations (scm) and cancer on bscb dysfunction. |
2024-11-01 |
2024-11-03 |
Not clear |
| Marius-Valentin Drăgoi, Ionuț Nisipeanu, Aurel Frimu, Ana-Maria Tălîngă, Anton Hadăr, Tiberiu Gabriel Dobrescu, Cosmin Petru Suciu, Andrei Rareș Mane. Real-Time Home Automation System Using BCI Technology. Biomimetics (Basel, Switzerland). vol 9. issue 10. 2024-10-26. PMID:39451800. |
the main purpose of bcis is to replace or restore the missing or damaged functions of disabled people, including in neuromuscular disorders like amyotrophic lateral sclerosis (als), cerebral palsy, stroke, or spinal cord injury. |
2024-10-26 |
2024-10-28 |
Not clear |
| Susanna De Stefano, Marta Tiberi, Illari Salvatori, Marco De Bardi, Juliette Gimenez, Mahsa Pirshayan, Viviana Greco, Giovanna Borsellino, Alberto Ferri, Cristiana Valle, Nicola B Mercuri, Valerio Chiurchiù, Alida Spalloni, Patrizia Longon. Hydrogen Sulfide Modulates Astrocytic Toxicity in Mouse Spinal Cord Cultures: Implications for Amyotrophic Lateral Sclerosis. Antioxidants (Basel, Switzerland). vol 13. issue 10. 2024-10-26. PMID:39456494. |
hydrogen sulfide modulates astrocytic toxicity in mouse spinal cord cultures: implications for amyotrophic lateral sclerosis. |
2024-10-26 |
2024-10-29 |
mouse |
| Correction to "Differential activation of neuronal and glial STAT3 in the spinal cord of the SOD1G93A mouse model of amyotrophic lateral sclerosis". The European journal of neuroscience. 2024-10-11. PMID:39392096. |
correction to "differential activation of neuronal and glial stat3 in the spinal cord of the sod1g93a mouse model of amyotrophic lateral sclerosis". |
2024-10-11 |
2024-10-13 |
mouse |
| Zahid Razzaq, Nihad Brahimi, Hafiz Zia Ur Rehman, Zeashan Hameed Kha. Intelligent Control System for Brain-Controlled Mobile Robot Using Self-Learning Neuro-Fuzzy Approach. Sensors (Basel, Switzerland). vol 24. issue 18. 2024-09-28. PMID:39338620. |
such interfaces have significantly improved the lives of disabled individuals suffering from neurological disorders-such as stroke, amyotrophic lateral sclerosis (als), and spinal cord injury-by extending their movement range and thereby promoting self-independence. |
2024-09-28 |
2024-10-01 |
human |
| Wenzhi Yang, Xiangyi Liu, Dongsheng Fa. Low CD3 level is a risk factor for amyotrophic lateral sclerosis: a Mendelian randomization study. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2024-09-24. PMID:39316061. |
amyotrophic lateral sclerosis (als) is a progressive and fatal disease characterized by neuronal degeneration of the spinal cord and brain and believed to be related to the immune system. |
2024-09-24 |
2024-09-26 |
Not clear |
| Deboral Eshak, Mohanapriya Arumuga. Unveiling therapeutic biomarkers and druggable targets in ALS: An integrative microarray analysis, molecular docking, and structural dynamic studies. Computational biology and chemistry. vol 113. 2024-09-19. PMID:39299050. |
amyotrophic lateral sclerosis (als), commonly known as lou gehrig's disease, is a debilitating neurodegenerative disorder characterized by the progressive degeneration of nerve cells in the brain and spinal cord. |
2024-09-19 |
2024-09-22 |
Not clear |
| Mingyu Zhang, Chunyu Xiang, Renrui Niu, Xiaodong He, Wenqi Luo, Wanguo Liu, Rui G. Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders: drug stability, targeting efficiency, and safety. Neural regeneration research. vol 20. issue 7. 2024-09-10. PMID:39254548. |
afterwards, we comprehensively discussed the current applications of liposomes in central nervous system diseases, such as alzheimer's disease, parkinson's disease, huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, spinal cord injury, and brain tumors. |
2024-09-10 |
2024-09-13 |
Not clear |
| Rachel J Sharkey, Filomeno Cortese, Bradley G Goodyear, Lawrence W Korngut, Sarah M Jacob, Keith A Sharkey, Sanjay Kalra, Minh Dang Nguyen, Richard Frayne, Gerald Pfeffe. Longitudinal analysis of glymphatic function in amyotrophic lateral sclerosis and primary lateral sclerosis. Brain : a journal of neurology. 2024-09-06. PMID:39241118. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder of motor neurons in the brain and spinal cord. |
2024-09-06 |
2024-09-09 |
human |
| Ali Shojaie, Ahmad Al Khleifat, Sarah Garrahy, Haniah Habash-Bailey, Rachel Thomson, Sarah Opie-Martin, Sara Javidnia, P Nigel Leigh, Ammar Al-Chalab. Investigating the impact of socioeconomic status on amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2024-09-01. PMID:39218010. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the gradual death of motor neurons in the brain and spinal cord, leading to fatal paralysis. |
2024-09-01 |
2024-09-04 |
human |