| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Valeria Valsecchi, Giovanna Lombardi, Serenella Anzilotti, Giorgia Andreozzi, Antonia Scognamiglio, Rosa Sparaco, Elisa Perissutti, Beatrice Severino, Michele Gargiulo, Vincenzo Santagada, Giuseppe Pignatar. Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice. ACS pharmacology & translational science. vol 7. issue 7. 2024-07-18. PMID:39022351. |
the debilitating neurodegenerative disease known as amyotrophic lateral sclerosis (als) is characterized by the progressive loss of motor neurons (mns) in the brain, spinal cord, and motor cortex. |
2024-07-18 |
2024-07-20 |
mouse |
| Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariott. Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally. European journal of histochemistry : EJH. vol 68. issue 3. 2024-07-04. PMID:38963135. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder involving motor neuron (mn) loss in the motor cortex, brainstem and spinal cord leading to progressive paralysis and death. |
2024-07-04 |
2024-07-10 |
mouse |
| Elisabetta Carata, Marco Muci, Stefania Mariano, Simona Di Giulio, Annamaria Nigro, Alessandro Romano, Elisa Panzarin. Extracellular Vesicles from NSC-34 MN-like Cells Transfected with Mutant SOD1 Modulate Inflammatory Status of Raw 264.7 Macrophages. Genes. vol 15. issue 6. 2024-06-27. PMID:38927671. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease targeting the brain and spinal cord. |
2024-06-27 |
2024-06-29 |
Not clear |
| Ching-Yi Lin, Veronica Vanoverbeke, David Trent, Kathryn Willey, Yu-Shang Le. The Spatiotemporal Expression of SOCS3 in the Brainstem and Spinal Cord of Amyotrophic Lateral Sclerosis Mice. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928564. |
the spatiotemporal expression of socs3 in the brainstem and spinal cord of amyotrophic lateral sclerosis mice. |
2024-06-27 |
2024-06-29 |
mouse |
| Ching-Yi Lin, Veronica Vanoverbeke, David Trent, Kathryn Willey, Yu-Shang Le. The Spatiotemporal Expression of SOCS3 in the Brainstem and Spinal Cord of Amyotrophic Lateral Sclerosis Mice. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928564. |
amyotrophic lateral sclerosis (als) is characterized by the progressive loss of motor neurons from the brain and spinal cord. |
2024-06-27 |
2024-06-29 |
mouse |
| Zoë Donders, Iga Joanna Skorupska, Emily Willems, Femke Mussen, Jana Van Broeckhoven, Aurélie Carlier, Melissa Schepers, Tim Vanmierl. Beyond PDE4 inhibition: A comprehensive review on downstream cAMP signaling in the central nervous system. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-06-22. PMID:38908196. |
thus, elevating camp levels through pde inhibition provides a therapeutic approach for multiple cns disorders, including multiple sclerosis, stroke, spinal cord injury, amyotrophic lateral sclerosis, traumatic brain injury, and alzheimer's disease. |
2024-06-22 |
2024-06-25 |
Not clear |
| Marlene Tahedl, Ee Ling Tan, Jana Kleinerova, Siobhan Delaney, Jennifer C Hengeveld, Mark A Doherty, Russell L Mclaughlin, Pierre-Francois Pradat, Cédric Raoul, Fabrice Ango, Orla Hardiman, Kai Ming Chang, Jasmin Lope, Peter Bed. Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis. Neurology. vol 103. issue 2. 2024-06-20. PMID:38900989. |
amyotrophic lateral sclerosis (als) is predominantly associated with motor cortex, corticospinal tract (cst), brainstem, and spinal cord degeneration, and cerebellar involvement is much less well characterized. |
2024-06-20 |
2024-06-23 |
Not clear |
| Sylwia Dabrowska, Ermanna Turano, Ilaria Scambi, Federica Virla, Alice Nodari, Francesco Pezzini, Mirco Galiè, Bruno Bonetti, Raffaella Mariott. A Cellular Model of Amyotrophic Lateral Sclerosis to Study the Therapeutic Effects of Extracellular Vesicles from Adipose Mesenchymal Stem Cells on Microglial Activation. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891895. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the progressive degeneration of upper and lower motor neurons (mns) in the brain and spinal cord, leading to progressive paralysis and death. |
2024-06-19 |
2024-06-21 |
human |
| Steven P Brow. Diagnosis of Cervical Spinal Cord Multiple Sclerosis by a Chiropractic Physician: A Case Report. Cureus. vol 16. issue 6. 2024-06-19. PMID:38894936. |
the differential diagnosis included lower cervical spine nerve root compression or neurological disorders such as amyotrophic lateral sclerosis, cerebral lesion, motor neuropathy, multiple sclerosis, or spinal cord lesion. |
2024-06-19 |
2024-06-21 |
Not clear |
| Brenda Murage, Han Tan, Tomoji Mashimo, Mandy Jackson, Paul A Skehe. Spinal cord neurone loss and foot placement changes in a rat knock-in model of amyotrophic lateral sclerosis Type 8. Brain communications. vol 6. issue 3. 2024-06-08. PMID:38846532. |
spinal cord neurone loss and foot placement changes in a rat knock-in model of amyotrophic lateral sclerosis type 8. |
2024-06-08 |
2024-06-10 |
rat |
| Seán C Ó Murchú, Ken D O'Hallora. BREATHE DMD: boosting respiratory efficacy after therapeutic hypoxic episodes in Duchenne muscular dystrophy. The Journal of physiology. 2024-06-05. PMID:38837229. |
various paradigms of intermittent hypoxia have been designed and implemented in human trials culminating in clinical trials in people with spinal cord injury and amyotrophic lateral sclerosis. |
2024-06-05 |
2024-06-08 |
human |
| Xingyuan Chen, Zhongwen Cao, Yinsheng Wan. Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Perturb mRNA Splicing through Aberrant Interactions with SRSF2. Analytical chemistry. 2024-05-25. PMID:38795036. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder that results in the degeneration of neurons in the brain and spinal cord. |
2024-05-25 |
2024-05-27 |
human |
| Zihao Li, Ye Zhang, Meiling Ji, Chenglong Wu, Yanxing Zhang, Senlin J. Targeting ferroptosis in neuroimmune and neurodegenerative disorders for the development of novel therapeutics. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 176. 2024-05-25. PMID:38795640. |
neurodegenerative diseases result from neuronal degeneration or demyelination in the brain or spinal cord, such as alzheimer's disease, parkinson's disease, huntington's disease, and amyotrophic lateral sclerosis. |
2024-05-25 |
2024-05-31 |
Not clear |
| Andrea Salzinger, Vidya Ramesh, Shreya Das Sharma, Siddharthan Chandran, Bhuvaneish Thangaraj Selvara. Neuronal Circuit Dysfunction in Amyotrophic Lateral Sclerosis. Cells. vol 13. issue 10. 2024-05-24. PMID:38786016. |
the primary neural circuit affected in amyotrophic lateral sclerosis (als) patients is the corticospinal motor circuit, originating in upper motor neurons (umns) in the cerebral motor cortex which descend to synapse with the lower motor neurons (lmns) in the spinal cord to ultimately innervate the skeletal muscle. |
2024-05-24 |
2024-05-27 |
human |
| Weijian Chen, Xu Liu, Peiyuan Wan, Zhijie Chen, Yi Che. Anti-artifacts techniques for neural recording front-ends in closed-loop brain-machine interface ICs. Frontiers in neuroscience. vol 18. 2024-05-24. PMID:38784093. |
particularly in the field of neuromedical, the utilization of brain-machine interfaces (bmi) has revolutionized the treatment of neurological diseases such as amyotrophic lateral sclerosis, cerebral palsy, stroke, or spinal cord injury. |
2024-05-24 |
2024-05-27 |
Not clear |
| Ilaria Martinelli, Jessica Mandrioli, Andrea Ghezzi, Elisabetta Zucchi, Giulia Gianferrari, Cecilia Simonini, Francesco Cavallieri, Franco Valzani. Multifaceted superoxide dismutase 1 expression in amyotrophic lateral sclerosis patients: a rare occurrence? Neural regeneration research. vol 20. issue 1. 2024-05-20. PMID:38767482. |
amyotrophic lateral sclerosis (als) is a neuromuscular condition resulting from the progressive degeneration of motor neurons in the cortex, brainstem, and spinal cord. |
2024-05-20 |
2024-05-27 |
human |
| Jiaqi Xin, Sen Huang, Jing Wen, Yunhao Li, Ang Li, Senthil Kumaran Satyanarayanan, Xiaoli Yao, Huanxing S. Drug Screening and Validation Targeting TDP-43 Proteinopathy for Amyotrophic Lateral Sclerosis. Aging and disease. 2024-05-13. PMID:38739934. |
amyotrophic lateral sclerosis (als) stands as a rare, yet severely debilitating disorder marked by the deterioration of motor neurons (mns) within the brain and spinal cord, which is accompanied by degenerated corticobulbar/corticospinal tracts and denervation in skeletal muscles. |
2024-05-13 |
2024-05-27 |
Not clear |
| Sangeetha Gupta, Uma Sharm. Metabolomics of neurological disorders in India. Analytical science advances. vol 2. issue 11-12. 2024-05-08. PMID:38715858. |
the current review mainly focuses on an indian perspective of metabolomics for the identification of metabolites and metabolic alterations serving as potential diagnostic biomarkers for neurological diseases including acute spinal cord injury, amyotrophic lateral sclerosis, tethered cord syndrome, spina bifida, stroke, parkinson's disease, glioblastoma and neurological disorders with inborn errors of metabolism. |
2024-05-08 |
2024-05-27 |
Not clear |
| Abdulkadir Ozkan, Hari K Padmanabhan, Seth L Shipman, Eiman Azim, Priyanka Kumar, Cameron Sadegh, A Nazli Basak, Jeffrey D Mackli. Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors. bioRxiv : the preprint server for biology. 2024-05-07. PMID:38712174. |
corticospinal neurons (csn) centrally degenerate in amyotrophic lateral sclerosis (als), along with spinal motor neurons, and loss of voluntary motor function in spinal cord injury (sci) results from damage to csn axons. |
2024-05-07 |
2024-05-27 |
Not clear |
| Arsh Ketabforoush, Meifang Wang, Catherine L Smith, William David Arnold, Nicole L Nichol. Assessing Rat Diaphragm Motor Unit Connectivity Outcome Measures as Quantitative Biomarkers of Phrenic Motor Neuron Degeneration and Compensation. Journal of visualized experiments : JoVE. issue 206. 2024-05-06. PMID:38709037. |
loss of ventilatory muscle function is a consequence of motor neuron injury and neurodegeneration (e.g., cervical spinal cord injury and amyotrophic lateral sclerosis, respectively). |
2024-05-06 |
2024-05-08 |
rat |