Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jeffrey S Phillips, Fulvio Da Re, Laynie Dratch, Sharon X Xie, David J Irwin, Corey T McMillan, Sanjeev N Vaishnavi, Carlo Ferrarese, Edward B Lee, Leslie M Shaw, John Q Trojanowski, David A Wolk, Murray Grossma. Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease. Neurobiology of aging. vol 63. 2018-09-26. PMID:29223682. |
amnestic alzheimer's disease (ad) is characterized by early atrophy of the hippocampus and medial temporal lobes before spreading to the neocortex. |
2018-09-26 |
2023-08-13 |
Not clear |
Jeffrey S Phillips, Fulvio Da Re, Laynie Dratch, Sharon X Xie, David J Irwin, Corey T McMillan, Sanjeev N Vaishnavi, Carlo Ferrarese, Edward B Lee, Leslie M Shaw, John Q Trojanowski, David A Wolk, Murray Grossma. Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease. Neurobiology of aging. vol 63. 2018-09-26. PMID:29223682. |
in contrast, nonamnestic alzheimer's patients have relative sparing of the hippocampus, but the pattern in which the disease spreads is unclear. |
2018-09-26 |
2023-08-13 |
Not clear |
Houze Zhu, Huanhuan Yan, Na Tang, Xinyan Li, Pei Pang, Hao Li, Wenting Chen, Yu Guo, Shu Shu, You Cai, Lei Pei, Dan Liu, Min-Hua Luo, Hengye Man, Qing Tian, Yangling Mu, Ling-Qiang Zhu, Youming L. Impairments of spatial memory in an Alzheimer's disease model via degeneration of hippocampal cholinergic synapses. Nature communications. vol 8. issue 1. 2018-09-24. PMID:29162816. |
impairments of spatial memory in an alzheimer's disease model via degeneration of hippocampal cholinergic synapses. |
2018-09-24 |
2023-08-13 |
mouse |
Guoyao Zang, Lizheng Fang, Liying Chen, Chenyao Wan. Ameliorative effect of nicergoline on cognitive function through the PI3K/AKT signaling pathway in mouse models of Alzheimer's disease. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568940. |
the apoptosis rates of hippocampal cells were studied in mice with alzheimer's disease treated with nicergoline compared with the negative control. |
2018-09-21 |
2023-08-13 |
mouse |
Guoyao Zang, Lizheng Fang, Liying Chen, Chenyao Wan. Ameliorative effect of nicergoline on cognitive function through the PI3K/AKT signaling pathway in mouse models of Alzheimer's disease. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568940. |
the results of the present study demonstrated that nicergoline ameliorated apoptosis in hippocampal cells and hippocampus tissue in 3xtg‑ad mice with alzheimer's disease. |
2018-09-21 |
2023-08-13 |
mouse |
Sooah Jang, Eun Woo Kim, Yinhua Zhang, Jimin Lee, So Yeon Cho, Junghee Ha, Hyunjeong Kim, Eosu Ki. Particulate matter increases beta-amyloid and activated glial cells in hippocampal tissues of transgenic Alzheimer's mouse: Involvement of PARP-1. Biochemical and biophysical research communications. vol 500. issue 2. 2018-09-19. PMID:29654761. |
particulate matter increases beta-amyloid and activated glial cells in hippocampal tissues of transgenic alzheimer's mouse: involvement of parp-1. |
2018-09-19 |
2023-08-13 |
mouse |
Young-Jung Kim, Ji-Young Yoo, Ok-Soon Kim, Han-Byeol Kim, Junghwa Ryu, Hye-Sun Kim, Jun-Ho Lee, Hong-Il Yoo, Dae-Yong Song, Tai-Kyoung Baik, Ran-Sook Wo. Neuregulin 1 regulates amyloid precursor protein cell surface expression and non-amyloidogenic processing. Journal of pharmacological sciences. vol 137. issue 2. 2018-09-07. PMID:29914798. |
furthermore, we found that the protein level of nrg1 was reduced in the hippocampus of alzheimer's disease (ad) patients. |
2018-09-07 |
2023-08-13 |
rat |
Melissa L Perreault, Theresa Fan, Tomek J Banasikowski, Anthony A Grace, Susan R Georg. The atypical dopamine receptor agonist SKF 83959 enhances hippocampal and prefrontal cortical neuronal network activity in a rat model of cognitive dysfunction. The European journal of neuroscience. vol 46. issue 4. 2018-09-06. PMID:28677227. |
deficits in neuronal network synchrony in hippocampus and prefrontal cortex have been widely demonstrated in disorders of cognitive dysfunction, including schizophrenia and alzheimer's disease. |
2018-09-06 |
2023-08-13 |
rat |
Zhihui Gai, Donghong Su, Yawen Wang, Wenlong Li, Bo Cui, Kang Li, Xiaojun She, Rui Wan. Effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to Alzheimer's disease-like tau hyperphosphorylation. Environmental health and preventive medicine. vol 22. issue 1. 2018-09-04. PMID:29228900. |
effects of chronic noise on the corticotropin-releasing factor system in the rat hippocampus: relevance to alzheimer's disease-like tau hyperphosphorylation. |
2018-09-04 |
2023-08-13 |
rat |
Shenq-Shyang Huang, Nan-Shan Chan. Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events. Experimental biology and medicine (Maywood, N.J.). vol 243. issue 2. 2018-09-04. PMID:29310447. |
notably, wwox with ser14 phosphorylation is upregulated in the lesions of cancer, as well as in the brain hippocampus and cortex with alzheimer's disease. |
2018-09-04 |
2023-08-13 |
human |
Qisen Li, Jiacheng Zeng, Meiling Su, Yu He, Banghao Zh. Acetylshikonin from Zicao attenuates cognitive impairment and hippocampus senescence in d-galactose-induced aging mouse model via upregulating the expression of SIRT1. Brain research bulletin. vol 137. 2018-08-31. PMID:29325995. |
in this study, we investigated the neuroprotective effect of acetylshikonin (as) from zicao on the hippocampus of the d-galactose (d-gal)-induced sub-acute aging mouse model of alzheimer's disease (ad). |
2018-08-31 |
2023-08-13 |
mouse |
Daniel H Adler, Laura E M Wisse, Ranjit Ittyerah, John B Pluta, Song-Lin Ding, Long Xie, Jiancong Wang, Salmon Kadivar, John L Robinson, Theresa Schuck, John Q Trojanowski, Murray Grossman, John A Detre, Mark A Elliott, Jon B Toledo, Weixia Liu, Stephen Pickup, Michael I Miller, Sandhitsu R Das, David A Wolk, Paul A Yushkevic. Characterizing the human hippocampus in aging and Alzheimer's disease using a computational atlas derived from ex vivo MRI and histology. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 16. 2018-08-29. PMID:29592955. |
characterizing the human hippocampus in aging and alzheimer's disease using a computational atlas derived from ex vivo mri and histology. |
2018-08-29 |
2023-08-13 |
human |
Li Ba, Xiao-Hua Chen, Yan-Lin Chen, Qing Nie, Zhi-Jun Li, Feng-Fei Ding, Min Zhan. Distinct Rab7-related Endosomal-Autophagic-Lysosomal Dysregulation Observed in Cortex and Hippocampus in APPswe/PSEN1dE9 Mouse Model of Alzheimer's Disease. Chinese medical journal. vol 130. issue 24. 2018-08-27. PMID:29237927. |
distinct rab7-related endosomal-autophagic-lysosomal dysregulation observed in cortex and hippocampus in appswe/psen1de9 mouse model of alzheimer's disease. |
2018-08-27 |
2023-08-13 |
mouse |
Tonia Munder, Anna Pfeffer, Stefanie Schreyer, Jing Guo, Juergen Braun, Ingolf Sack, Barbara Steiner, Charlotte Klei. MR elastography detection of early viscoelastic response of the murine hippocampus to amyloid β accumulation and neuronal cell loss due to Alzheimer's disease. Journal of magnetic resonance imaging : JMRI. vol 47. issue 1. 2018-08-23. PMID:28422391. |
mr elastography detection of early viscoelastic response of the murine hippocampus to amyloid β accumulation and neuronal cell loss due to alzheimer's disease. |
2018-08-23 |
2023-08-13 |
Not clear |
Tonia Munder, Anna Pfeffer, Stefanie Schreyer, Jing Guo, Juergen Braun, Ingolf Sack, Barbara Steiner, Charlotte Klei. MR elastography detection of early viscoelastic response of the murine hippocampus to amyloid β accumulation and neuronal cell loss due to Alzheimer's disease. Journal of magnetic resonance imaging : JMRI. vol 47. issue 1. 2018-08-23. PMID:28422391. |
to investigate in vivo viscoelastic parameters related to early histopathological changes in the hippocampus and the cortex in early, preclinical alzheimer's disease (ad) stages. |
2018-08-23 |
2023-08-13 |
Not clear |
Angela Gomez-Arboledas, Jose C Davila, Elisabeth Sanchez-Mejias, Victoria Navarro, Cristina Nuñez-Diaz, Raquel Sanchez-Varo, Maria Virtudes Sanchez-Mico, Laura Trujillo-Estrada, Juan Jose Fernandez-Valenzuela, Marisa Vizuete, Joan X Comella, Elena Galea, Javier Vitorica, Antonia Gutierre. Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease. Glia. vol 66. issue 3. 2018-08-23. PMID:29178139. |
reactive astrocytes surrounding and engulfing dystrophic neurites were also detected in the hippocampus of alzheimer's patients by confocal and ultrastructural analysis. |
2018-08-23 |
2023-08-13 |
mouse |
Sahreh Shabani, Yaghoob Farbood, Seyyed Ali Mard, Alireza Sarkaki, Akram Ahangarpour, Layasadat Khorsand. The regulation of pituitary-thyroid abnormalities by peripheral administration of levothyroxine increased brain-derived neurotrophic factor and reelin protein expression in an animal model of Alzheimer's disease. Canadian journal of physiology and pharmacology. vol 96. issue 3. 2018-08-20. PMID:28846851. |
alzheimer's disease (ad) is associated with decreased serum levels of thyroid hormones (ths), increased levels of thyroid-stimulating hormone (tsh), and decreased protein expression of brain-derived neurotrophic factor (bdnf) and reelin in the hippocampus. |
2018-08-20 |
2023-08-13 |
Not clear |
Manikandan Samidurai, Vijay S Ramasamy, Jihoon J. β-amyloid inhibits hippocampal LTP through TNFR/IKK/NF-κB pathway. Neurological research. vol 40. issue 4. 2018-08-20. PMID:29458298. |
methods acute hippocampal slices of male wildtype or alzheimer's disease (ad) transgenic mouse models were treated with the inhibitors of either tnf-α, iκb kinase (ikk) or nuclear factor-κb (nf-κb) in the presence or absence of oligomeric aβ |
2018-08-20 |
2023-08-13 |
mouse |
Xiaocong Pang, Ying Zhao, Jinhua Wang, Qimeng Zhou, Lvjie Xu, De Kang, Ai-Lin Liu, Guan-Hua D. The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer's Disease. BioMed research international. vol 2017. 2018-08-14. PMID:29359159. |
the bioinformatic analysis of the dysregulated genes and micrornas in entorhinal cortex, hippocampus, and blood for alzheimer's disease. |
2018-08-14 |
2023-08-13 |
Not clear |
Jack Cheng, Hsin-Ping Liu, Cheng-Chun Lee, Mei-Ying Chen, Wei-Yong Lin, Fuu-Jen Tsa. Matrix metalloproteinase 14 modulates diabetes and Alzheimer's disease cross-talk: a meta-analysis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 39. issue 2. 2018-08-13. PMID:29103177. |
expression profiling of amyloid beta-degrading enzymes in streptozotocin-induced diabetic mice and their correlation with expression of amyloid precursor protein in hippocampus of alzheimer's disease patients were accessed. |
2018-08-13 |
2023-08-13 |
mouse |