| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesca Palombo, Francesco Masia, Sara Mattana, Francesco Tamagnini, Paola Borri, Wolfgang Langbein, Daniele Fiorett. Hyperspectral analysis applied to micro-Brillouin maps of amyloid-beta plaques in Alzheimer's disease brains. The Analyst. vol 143. issue 24. 2019-01-16. PMID:30460364. |
a recent investigation on the architecture and chemical composition of amyloid-β (aβ) plaques in ex vivo histological sections of an aβ-overexpressing transgenic mouse hippocampus has shed light on the infrared light signature of cell-activation related biomarkers of alzheimer's disease. |
2019-01-16 |
2023-08-13 |
mouse |
| Andrea Slachevsky, Paulo Barraza, Michael Hornberger, Carlos Muñoz-Neira, Emma Flanagan, Fernando Henríquez, Eduardo Bravo, Mauricio Farías, Carolina Delgad. Neuroanatomical Comparison of the "Word" and "Picture" Versions of the Free and Cued Selective Reminding Test in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 61. issue 2. 2019-01-15. PMID:29226861. |
episodic memory tests with cued recall, such as the free and cued selective reminding test (fcsrt), allow for the delineation of hippocampal and prefrontal atrophy contributions to memory performance in alzheimer's disease (ad). |
2019-01-15 |
2023-08-13 |
human |
| Rodrigo D Perea, Jennifer S Rabin, Megan G Fujiyoshi, Taylor E Neal, Emily E Smith, Koene R A Van Dijk, Trey Hedde. Connectome-derived diffusion characteristics of the fornix in Alzheimer's disease. NeuroImage. Clinical. vol 19. 2019-01-15. PMID:30013916. |
while volume of the hippocampus has been a primary imaging biomarker of alzheimer's disease progression, recent research has suggested that the volume and microstructural characteristics of the fornix bundle connecting the hippocampus could add relevant information for diagnosing and staging alzheimer's disease. |
2019-01-15 |
2023-08-13 |
human |
| Christian Lambert, Eva Zeestraten, Owen Williams, Philip Benjamin, Andrew J Lawrence, Robin G Morris, Andrew D Mackinnon, Thomas R Barrick, Hugh S Marku. Identifying preclinical vascular dementia in symptomatic small vessel disease using MRI. NeuroImage. Clinical. vol 19. 2019-01-14. PMID:30003030. |
voxel-wise rates of hippocampal atrophy supported these distinctions, with the vascular group closely resembling the non-dementing cohort, whereas the alzheimer's like group demonstrated global hippocampal atrophy. |
2019-01-14 |
2023-08-13 |
human |
| Kagaku Azuma, Tatsuya Toyama, Masahisa Katano, Kyoko Kajimoto, Sakurako Hayashi, Ayumi Suzuki, Hiroko Tsugane, Mitsuo Iinuma, Kin-Ya Kub. Yokukansan Ameliorates Hippocampus-Dependent Learning Impairment in Senescence-Accelerated Mouse. Biological & pharmaceutical bulletin. vol 41. issue 10. 2019-01-11. PMID:30270329. |
we investigated the effect of yks on learning ability, hippocampal cell proliferation, and neural ultrastructural features in senescence-accelerated mouse prone 8 (samp8), a proposed animal model of alzheimer's disease. |
2019-01-11 |
2023-08-13 |
mouse |
| Meng-Ming Hu, Xu-Dong Yan, Xiu-Min Zhang, Yu Bai, Fang Zhao, Jin-Shun Q. [Application of wireless neuronal recording system in fear conditioning of Alzheimer's disease mice - hippocampal Theta oscillation observation]. Sheng li xue bao : [Acta physiologica Sinica]. vol 70. issue 5. 2019-01-08. PMID:30377697. |
[application of wireless neuronal recording system in fear conditioning of alzheimer's disease mice - hippocampal theta oscillation observation]. |
2019-01-08 |
2023-08-13 |
mouse |
| Raphael Hesse, Bjoern von Einem, Franziska Wagner, Patricia Bott, Daniel Schwanzar, Rosemary J Jackson, Karl Josef Föhr, Ludwig Lausser, Katja S Kroker, Christian Proepper, Paul Walther, Hans A Kestler, Tara L Spires-Jones, Tobias Boeckers, Holger Rosenbrock, Christine A F von Arni. sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Ca Experimental neurology. vol 304. 2019-01-07. PMID:29466703. |
sappβ and sappα increase structural complexity and e/i input ratio in primary hippocampal neurons and alter ca one major pathophysiological hallmark of alzheimer's disease (ad) is senile plaques composed of amyloid β (aβ). |
2019-01-07 |
2023-08-13 |
human |
| Ramesh Kandimalla, Maria Manczak, Xiangling Yin, Rui Wang, P Hemachandra Redd. Hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of Alzheimer's disease. Human molecular genetics. vol 27. issue 1. 2019-01-02. PMID:29040533. |
hippocampal phosphorylated tau induced cognitive decline, dendritic spine loss and mitochondrial abnormalities in a mouse model of alzheimer's disease. |
2019-01-02 |
2023-08-13 |
mouse |
| Maria Kovalska, Barbara Tothova, Libusa Kovalska, Zuzana Tatarkova, Dagmar Kalenska, Anna Tomascova, Marian Adamkov, Jan Lehotsk. Association of Induced Hyperhomocysteinemia with Alzheimer's Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury. Neurochemical research. vol 43. issue 9. 2018-12-31. PMID:30003389. |
alzheimer's disease (ad) is a progressive and irreversible neurodegenerative disorder that results in massive hippocampal and neocortical neuronal loss leading to dementia and eventual death. |
2018-12-31 |
2023-08-13 |
rat |
| Badrah Saeed Ali Alghamd. Possible prophylactic anti-excitotoxic and anti-oxidant effects of virgin coconut oil on aluminium chloride-induced Alzheimer's in rat models. Journal of integrative neuroscience. vol 17. issue 3-4. 2018-12-26. PMID:30010139. |
alzheimer was induced by intraperitoneal injections of aluminium chloride (alcl3) for 45 days (40 ml/kg per day), and our results showed that oral administration of vco (5 ml per day for 30 days) prior to the administration of alcl3 significantly reduced the glutamate level in both the hippocampus and prefrontal cortex compared to an vco non-administrated ad group. |
2018-12-26 |
2023-08-13 |
rat |
| Robert H Pietrzak, Simon M Laws, Yen Ying Lim, Sophie J Bender, Tenielle Porter, James Doecke, David Ames, Christopher Fowler, Colin L Masters, Lidija Milicic, Stephanie Rainey-Smith, Victor L Villemagne, Christopher C Rowe, Ralph N Martins, Paul Maruf. Plasma Cortisol, Brain Amyloid-β, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 2. issue 1. 2018-12-19. PMID:29560886. |
hypothalamic-pituitary-adrenal axis dysregulation, which is typically assessed by measuring cortisol levels, is associated with cognitive dysfunction, hippocampal atrophy, and increased risk for mild cognitive impairment and alzheimer's disease (ad). |
2018-12-19 |
2023-08-13 |
Not clear |
| Seong Gak Jeon, Yong Jun Kim, Kyoung Ah Kim, Inhee Mook-Jung, Minho Moo. Visualization of Altered Hippocampal Connectivity in an Animal Model of Alzheimer's Disease. Molecular neurobiology. vol 55. issue 10. 2018-12-18. PMID:29488134. |
visualization of altered hippocampal connectivity in an animal model of alzheimer's disease. |
2018-12-18 |
2023-08-13 |
mouse |
| Seong Gak Jeon, Yong Jun Kim, Kyoung Ah Kim, Inhee Mook-Jung, Minho Moo. Visualization of Altered Hippocampal Connectivity in an Animal Model of Alzheimer's Disease. Molecular neurobiology. vol 55. issue 10. 2018-12-18. PMID:29488134. |
alzheimer's disease (ad) is a neurodegenerative disorder characterized by cognitive decline and neurodegeneration in the hippocampus. |
2018-12-18 |
2023-08-13 |
mouse |
| Amanda Worker, Danai Dima, Anna Combes, William R Crum, Johannes Streffer, Steven Einstein, Mitul A Mehta, Gareth J Barker, Steve C R Williams, Owen O'dal. Test-retest reliability and longitudinal analysis of automated hippocampal subregion volumes in healthy ageing and Alzheimer's disease populations. Human brain mapping. vol 39. issue 4. 2018-12-17. PMID:29341323. |
test-retest reliability and longitudinal analysis of automated hippocampal subregion volumes in healthy ageing and alzheimer's disease populations. |
2018-12-17 |
2023-08-13 |
human |
| Amanda Worker, Danai Dima, Anna Combes, William R Crum, Johannes Streffer, Steven Einstein, Mitul A Mehta, Gareth J Barker, Steve C R Williams, Owen O'dal. Test-retest reliability and longitudinal analysis of automated hippocampal subregion volumes in healthy ageing and Alzheimer's disease populations. Human brain mapping. vol 39. issue 4. 2018-12-17. PMID:29341323. |
in this study, an automated hippocampal subregion segmentation pipeline, released as a developmental version of freesurfer (v6.0), was applied to t1-weighted magnetic resonance imaging (mri) scans of 22 healthy older participants, scanned on 3 separate occasions and a separate longitudinal dataset of 40 alzheimer's disease (ad) patients. |
2018-12-17 |
2023-08-13 |
human |
| Pablo Galeano, María C Leal, Carina C Ferrari, María C Dalmasso, Pamela V Martino Adami, María I Farías, Juan C Casabona, Mariana Puntel, Sonia Do Carmo, Clara Smal, Martín Arán, Eduardo M Castaño, Fernando J Pitossi, A Claudio Cuello, Laura Morell. Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer. Molecular neurobiology. vol 55. issue 11. 2018-12-17. PMID:29582397. |
chronic hippocampal expression of notch intracellular domain induces vascular thickening, reduces glucose availability, and exacerbates spatial memory deficits in a rat model of early alzheimer. |
2018-12-17 |
2023-08-13 |
rat |
| Mirela Sarbu, Željka Vukelić, David E Clemmer, Alina D Zamfi. Ion mobility mass spectrometry provides novel insights into the expression and structure of gangliosides in the normal adult human hippocampus. The Analyst. vol 143. issue 21. 2018-12-17. PMID:30272072. |
a series of neuropsychiatric disorders, including alzheimer's disease and schizophrenia, are characterized by amnesia and disorientation caused by hippocampal atrophy and diminished cholinergic activity. |
2018-12-17 |
2023-08-13 |
human |
| Christine L Tardif, Gabriel A Devenyi, Robert S C Amaral, Sandra Pelleieux, Judes Poirier, Pedro Rosa-Neto, John Breitner, M Mallar Chakravart. Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease. Human brain mapping. vol 39. issue 2. 2018-12-11. PMID:29164798. |
regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical alzheimer's disease. |
2018-12-11 |
2023-08-13 |
human |
| Christine L Tardif, Gabriel A Devenyi, Robert S C Amaral, Sandra Pelleieux, Judes Poirier, Pedro Rosa-Neto, John Breitner, M Mallar Chakravart. Regionally specific changes in the hippocampal circuitry accompany progression of cerebrospinal fluid biomarkers in preclinical Alzheimer's disease. Human brain mapping. vol 39. issue 2. 2018-12-11. PMID:29164798. |
neuropathological and in vivo brain imaging studies agree that the cornu ammonis 1 and subiculum subfields of the hippocampus are most vulnerable to atrophy in the prodromal phases of alzheimer's disease (ad). |
2018-12-11 |
2023-08-13 |
human |
| Yu-Chia Kao, I-Fang Wang, Kuen-Jer Tsa. miRNA-34c Overexpression Causes Dendritic Loss and Memory Decline. International journal of molecular sciences. vol 19. issue 8. 2018-12-11. PMID:30096777. |
this study hypothesized that mir-34c, a mirna expressed in mammalian hippocampi whose expression level can alter the hippocampal dendritic spine density, could induce memory impairment akin to that of patients with alzheimer's disease (ad) in mice. |
2018-12-11 |
2023-08-13 |
mouse |