| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Alexandre Bejanin, Stéphanie Egret, Alice Pélerin, Florence Mézenge, Serge Belliard, Vincent de La Sayette, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer's and semantic dementia-targeted networks. Neuron. vol 81. issue 6. 2014-05-21. PMID:24656258. |
alzheimer's disease (ad) and semantic dementia (sd) are both characterized by severe atrophy in the hippocampus, a brain region underlying episodic memory; paradoxically, episodic memory is relatively preserved in sd. |
2014-05-21 |
2023-08-12 |
Not clear |
| Lei Li, Liling Yu, Qingxia Kon. Exogenous galanin attenuates spatial memory impairment and decreases hippocampal β-amyloid levels in rat model of Alzheimer's disease. The International journal of neuroscience. vol 123. issue 11. 2014-05-19. PMID:23687905. |
exogenous galanin attenuates spatial memory impairment and decreases hippocampal β-amyloid levels in rat model of alzheimer's disease. |
2014-05-19 |
2023-08-12 |
rat |
| You Yu, Yan Zhan. Desflurane accelerates neuronal cytotoxicity of Aβ by downregulating miR-214. Neuroscience letters. vol 554. 2014-05-16. PMID:24021802. |
since more and more evidence suggests anesthetics serve as a risk factor of alzheimer's disease (ad), we examine the neurotoxicity of a commonly used inhalational anesthetics, desflurane, and its potential toxicity mechanism in primary rat hippocampal neurons. |
2014-05-16 |
2023-08-12 |
rat |
| J J Rodríguez, H N Noristani, T Hilditch, M Olabarria, C Y Yeh, J Witton, A Verkhratsk. Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience letters. vol 552. 2014-05-15. PMID:23827221. |
increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the ca1 subfield of the hippocampus in the triple transgenic model of alzheimer's disease. |
2014-05-15 |
2023-08-12 |
mouse |
| J J Rodríguez, H N Noristani, T Hilditch, M Olabarria, C Y Yeh, J Witton, A Verkhratsk. Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience letters. vol 552. 2014-05-15. PMID:23827221. |
alzheimer's disease (ad) is an irreversible neurodegenerative disease that is characterised by the presence of β-amyloid (aβ) plaques, neurofibrillary tangles (nfts) and synaptic loss specifically in brain regions involved in learning and memory such as the neocortex and the hippocampus. |
2014-05-15 |
2023-08-12 |
mouse |
| Marco Vacante, Gordon K Wilcock, Celeste A de Jage. Computerized adaptation of The Placing Test for early detection of both mild cognitive impairment and Alzheimer's disease. Journal of clinical and experimental neuropsychology. vol 35. issue 8. 2014-05-15. PMID:23985007. |
changes in the hippocampal system have been proposed as a possible marker of incipient alzheimer's disease (ad) at the mild cognitive impairment (mci) stage. |
2014-05-15 |
2023-08-12 |
human |
| Elizabeth Gemmell, Edward Tam, Louise Allan, Roslyn Hall, Ahmad Khundakar, Arthur E Oakley, Alan Thomas, Vincent Deramecourt, Raj N Kalari. Neuron volumes in hippocampal subfields in delayed poststroke and aging-related dementias. Journal of neuropathology and experimental neurology. vol 73. issue 4. 2014-05-12. PMID:24607963. |
hippocampal atrophy is widely recognized in alzheimer disease (ad). |
2014-05-12 |
2023-08-12 |
human |
| Nadine Crouzin, Kevin Baranger, Mélanie Cavalier, Yannick Marchalant, Catherine Cohen-Solal, François S Roman, Michel Khrestchatisky, Santiago Rivera, François Féron, Michel Vigne. Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus. PloS one. vol 8. issue 9. 2014-05-08. PMID:24069328. |
area-specific alterations of synaptic plasticity in the 5xfad mouse model of alzheimer's disease: dissociation between somatosensory cortex and hippocampus. |
2014-05-08 |
2023-08-12 |
mouse |
| Nadine Crouzin, Kevin Baranger, Mélanie Cavalier, Yannick Marchalant, Catherine Cohen-Solal, François S Roman, Michel Khrestchatisky, Santiago Rivera, François Féron, Michel Vigne. Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus. PloS one. vol 8. issue 9. 2014-05-08. PMID:24069328. |
transgenic mouse models of alzheimer's disease (ad) that overproduce the amyloid beta peptide (aβ) have highlighted impairments of hippocampal long-term synaptic plasticity associated with the progression of the disease. |
2014-05-08 |
2023-08-12 |
mouse |
| Reza Rahimian, Gohar Fakhfouri, Shahram Ejtemaei Mehr, Jean-Eric Ghia, Armando A Genazzani, Borna Payandemehr, Ahmad Reza Dehpour, Kazem Mousavizadeh, Dmitry Li. Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats. European journal of clinical investigation. vol 43. issue 10. 2014-05-07. PMID:23937291. |
alzheimer's disease (ad) is a neurodegenerative disorder featured by deposition of beta-amyloid (aβ) plaques in the hippocampus and associated cortices and progressive cognitive decline. |
2014-05-07 |
2023-08-12 |
rat |
| Maël Lebreton, Maxime Bertoux, Claire Boutet, Stéphane Lehericy, Bruno Dubois, Philippe Fossati, Mathias Pessiglion. A critical role for the hippocampus in the valuation of imagined outcomes. PLoS biology. vol 11. issue 10. 2014-05-06. PMID:24167442. |
conversely, patients with hippocampus atrophy due to alzheimer's disease, but not patients with fronto-temporal dementia, were less inclined to favor options that required mental simulation. |
2014-05-06 |
2023-08-12 |
human |
| J Carson Smith, Kristy A Nielson, John L Woodard, Michael Seidenberg, Sally Durgerian, Kathleen E Hazlett, Christina M Figueroa, Cassandra C Kandah, Christina D Kay, Monica A Matthews, Stephen M Ra. Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease. Frontiers in aging neuroscience. vol 6. 2014-05-05. PMID:24795624. |
physical activity reduces hippocampal atrophy in elders at genetic risk for alzheimer's disease. |
2014-05-05 |
2023-08-13 |
human |
| J Carson Smith, Kristy A Nielson, John L Woodard, Michael Seidenberg, Sally Durgerian, Kathleen E Hazlett, Christina M Figueroa, Cassandra C Kandah, Christina D Kay, Monica A Matthews, Stephen M Ra. Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease. Frontiers in aging neuroscience. vol 6. 2014-05-05. PMID:24795624. |
we examined the impact of physical activity (pa) on longitudinal change in hippocampal volume in cognitively intact older adults at varying genetic risk for the sporadic form of alzheimer's disease (ad). |
2014-05-05 |
2023-08-13 |
human |
| K Nho, J J Corneveaux, S Kim, H Lin, S L Risacher, L Shen, S Swaminathan, V K Ramanan, Y Liu, T Foroud, M H Inlow, A L Siniard, R A Reiman, P S Aisen, R C Petersen, R C Green, C R Jack, M W Weiner, C T Baldwin, K Lunetta, L A Farrer, S J Furney, S Lovestone, A Simmons, P Mecocci, B Vellas, M Tsolaki, I Kloszewska, H Soininen, B C McDonald, M R Farlow, B Ghetti, M J Huentelman, A J Sayki. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Molecular psychiatry. vol 18. issue 7. 2014-05-02. PMID:23608917. |
matched unrelated apoe ε3 homozygous male caucasian participants from the alzheimer's disease neuroimaging initiative (adni) were selected at the extremes of the 2-year longitudinal change distribution of hippocampal volume (eight subjects with rapid rates of atrophy and eight with slow/stable rates of atrophy). |
2014-05-02 |
2023-08-12 |
human |
| Heather M Francis, Mehdi Mirzaei, Margery C Pardey, Paul A Haynes, Jennifer L Cornis. Proteomic analysis of the dorsal and ventral hippocampus of rats maintained on a high fat and refined sugar diet. Proteomics. vol 13. issue 20. 2014-04-29. PMID:23963966. |
the typical western diet, rich in high saturated fat and refined sugar (hfs), has been shown to increase cognitive decline with aging and alzheimer's disease, and to affect cognitive functions that are dependent on the hippocampus, including memory processes and reversal learning. |
2014-04-29 |
2023-08-12 |
rat |
| Tomoyuki Nagata, Shunichiro Shinagawa, Yusuke Ochiai, Ryo Aoki, Hiroo Kasahara, Kazutaka Nukariya, Kazuhiko Nakayam. Association between executive dysfunction and hippocampal volume in Alzheimer's disease. International psychogeriatrics. vol 23. issue 5. 2014-04-25. PMID:21106135. |
association between executive dysfunction and hippocampal volume in alzheimer's disease. |
2014-04-25 |
2023-08-12 |
Not clear |
| A Brück, J R Virta, J Koivunen, J Koikkalainen, N M Scheinin, H Helenius, K Någren, S Helin, R Parkkola, M Viitanen, J O Rinn. [11C]PIB, [18F]FDG and MR imaging in patients with mild cognitive impairment. European journal of nuclear medicine and molecular imaging. vol 40. issue 10. 2014-04-24. PMID:23801168. |
cortical glucose metabolism, brain amyloid β accumulation and hippocampal atrophy imaging have all been suggested as potential biomarkers in predicting which patients with mild cognitive impairment (mci) will convert to alzheimer's disease (ad). |
2014-04-24 |
2023-08-12 |
Not clear |
| Mareike Müller, H Bea Kuiperij, Jurgen A Claassen, Benno Küsters, Marcel M Verbee. MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid. Neurobiology of aging. vol 35. issue 1. 2014-04-23. PMID:23962497. |
micrornas in alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid. |
2014-04-23 |
2023-08-12 |
human |
| Mareike Müller, H Bea Kuiperij, Jurgen A Claassen, Benno Küsters, Marcel M Verbee. MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid. Neurobiology of aging. vol 35. issue 1. 2014-04-23. PMID:23962497. |
in this study, we aimed to identify mirnas with a differential expression in either hippocampus or cerebrospinal fluid (csf) from alzheimer's disease (ad) patients and age-matched nondemented control subjects using quantitative polymerase chain reaction. |
2014-04-23 |
2023-08-12 |
human |
| Bruno Duboi. [A new definition for Alzheimer's disease]. Bulletin de l'Academie nationale de medecine. vol 197. issue 1. 2014-04-23. PMID:24672986. |
there is a growing consensus that alzheimer's disease (ad) should be considered as a clinical-biological entity characterized by: i) a well-defined clinical phenotype (an amnestic syndrome of the hippocampal type in typical ad), and ii) biomarkers, especially pathophysiological biomarkers, of the underlying disease process. |
2014-04-23 |
2023-08-12 |
Not clear |