| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alice Krezymon, Kevin Richetin, Hélène Halley, Laurent Roybon, Jean-Michel Lassalle, Bernard Francès, Laure Verret, Claire Rampo. Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease. PloS one. vol 8. issue 9. 2014-06-16. PMID:24086745. |
ultimately, both events may constitute key components of hippocampal dysfunction and associated cognitive deficits occurring in alzheimer's disease. |
2014-06-16 |
2023-08-12 |
mouse |
| Zhuren Luo, Xiongjie Zhuang, Dushyant Kumar, Xiurong Wu, Cen Yue, Chengkun Han, Jiancheng L. The correlation of hippocampal T2-mapping with neuropsychology test in patients with Alzheimer's disease. PloS one. vol 8. issue 9. 2014-06-16. PMID:24098779. |
the correlation of hippocampal t2-mapping with neuropsychology test in patients with alzheimer's disease. |
2014-06-16 |
2023-08-12 |
Not clear |
| Zhuren Luo, Xiongjie Zhuang, Dushyant Kumar, Xiurong Wu, Cen Yue, Chengkun Han, Jiancheng L. The correlation of hippocampal T2-mapping with neuropsychology test in patients with Alzheimer's disease. PloS one. vol 8. issue 9. 2014-06-16. PMID:24098779. |
1) to deduce t2, the inverse of the transverse relaxation rate (r2), in the hippocampus of healthy adults; 2) to investigate the brain iron deposition in alzheimer's disease (ad) patients and age-matched healthy controls using t2-values. |
2014-06-16 |
2023-08-12 |
Not clear |
| Elena L Paley, George Perry, Olga Sokolov. Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency. Current Alzheimer research. vol 10. issue 9. 2014-06-15. PMID:24117115. |
we identified axonal defects in hippocampus of tryptamine- treated mice similar to those observed in human brain of patients with alzheimer's disease, multiple sclerosis and epilepsy using anti-trprs site-directed antibodies. |
2014-06-15 |
2023-08-12 |
mouse |
| N He, W-L Jin, K-H Lok, Y Wang, M Yin, Z-J Wan. Amyloid-β(1-42) oligomer accelerates senescence in adult hippocampal neural stem/progenitor cells via formylpeptide receptor 2. Cell death & disease. vol 4. 2014-06-12. PMID:24263098. |
the failure of adult hippocampal neurogenesis is increasingly considered as an important factor in the pathological correlates for memory decline in alzheimer's disease (ad). |
2014-06-12 |
2023-08-12 |
mouse |
| H-M Yun, H S Kim, K-R Park, J M Shin, A R Kang, K il Lee, S Song, Y-B Kim, S B Han, H-M Chung, J T Hon. Placenta-derived mesenchymal stem cells improve memory dysfunction in an Aβ1-42-infused mouse model of Alzheimer's disease. Cell death & disease. vol 4. 2014-06-12. PMID:24336078. |
these data indicate that pd-msc mediates neuroprotection by regulating neuronal death, neurogenesis, glia cell activation in hippocampus, and altering cytokine expression, suggesting a close link between the therapeutic effects of mscs and the damaged cns in alzheimer's disease. |
2014-06-12 |
2023-08-12 |
mouse |
| Amy M Pooler, Manuela Polydoro, Susanne K Wegmann, Rose Pitstick, Kevin R Kay, Laura Sanchez, George A Carlson, Teresa Gomez-Isla, Mark W Albers, Tara L Spires-Jones, Bradley T Hyma. Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology. The Journal of comparative neurology. vol 521. issue 18. 2014-06-11. PMID:23839581. |
the first neurofibrillary cortical lesions in alzheimer's disease occur in the entorhinal cortex, thereby disrupting the origin of the perforant pathway projection to the hippocampus, and amyloid deposits are often found in the molecular layer of the dentate gyrus, which is the terminal zone of the entorhinal cortex. |
2014-06-11 |
2023-08-12 |
mouse |
| Sylvia E Perez, Mary Ann Raghanti, Patrick R Hof, Lynn Kramer, Milos D Ikonomovic, Pascale N Lacor, Joseph M Erwin, Chet C Sherwood, Elliott J Mufso. Alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (Gorilla gorilla gorilla). The Journal of comparative neurology. vol 521. issue 18. 2014-06-11. PMID:23881733. |
alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (gorilla gorilla gorilla). |
2014-06-11 |
2023-08-12 |
Not clear |
| Melissa C Duff, Diana R Gallegos, Neal J Cohen, Daniel Trane. Learning in Alzheimer's disease is facilitated by social interaction. The Journal of comparative neurology. vol 521. issue 18. 2014-06-11. PMID:23881834. |
seminal work in gary van hoesen's laboratory at iowa in the early 1980s established that the hallmark neuropathology of alzheimer's disease (ad; neurofibrillary tangles) had its first foothold in specific parts of the hippocampal formation and entorhinal cortex, effectively isolating the hippocampus from much of its input and output and causing the distinctive impairment of new learning that is the leading early characteristic of the disease (hyman et al., 1984). |
2014-06-11 |
2023-08-12 |
human |
| Lucy A Crompton, Meg L Byrne, Hannah Taylor, Talitha L Kerrigan, Gilles Bru-Mercier, Jennifer L Badger, Peter A Barbuti, Jihoon Jo, Sue J Tyler, Shelley J Allen, Tilo Kunath, Kwangwook Cho, Maeve A Caldwel. Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling. Stem cell research. vol 11. issue 3. 2014-06-07. PMID:24013066. |
basal forebrain cholinergic neurons (bfcns) which provide innervation to the hippocampus and cortex, are required for memory and learning, and are primarily affected in alzheimer's disease (ad), resulting in related cognitive decline. |
2014-06-07 |
2023-08-12 |
human |
| B Barak, I Shvarts-Serebro, S Modai, A Gilam, E Okun, D M Michaelson, M P Mattson, N Shomron, U Asher. Opposing actions of environmental enrichment and Alzheimer's disease on the expression of hippocampal microRNAs in mouse models. Translational psychiatry. vol 3. 2014-06-05. PMID:24022509. |
opposing actions of environmental enrichment and alzheimer's disease on the expression of hippocampal micrornas in mouse models. |
2014-06-05 |
2023-08-12 |
mouse |
| Paula M Canas, Ana Patrícia Simões, Ricardo J Rodrigues, Rodrigo A Cunh. Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease. Neuropharmacology. vol 76 Pt A. 2014-06-05. PMID:24029236. |
alzheimer's disease (ad) is characterized phenotypically by memory impairment, neurochemically by accumulation of β-amyloid peptide (such as aβ1-42) and morphologically by an initial loss of nerve terminals in cortical and hippocampal regions. |
2014-06-05 |
2023-08-12 |
mouse |
| Pierre Lau, Koen Bossers, Rekin's Janky, Evgenia Salta, Carlo Sala Frigerio, Shahar Barbash, Roy Rothman, Annerieke S R Sierksma, Amantha Thathiah, David Greenberg, Aikaterini S Papadopoulou, Tilmann Achsel, Torik Ayoubi, Hermona Soreq, Joost Verhaagen, Dick F Swaab, Stein Aerts, Bart De Stroope. Alteration of the microRNA network during the progression of Alzheimer's disease. EMBO molecular medicine. vol 5. issue 10. 2014-06-03. PMID:24014289. |
an overview of mirnas altered in alzheimer's disease (ad) was established by profiling the hippocampus of a cohort of 41 late-onset ad (load) patients and 23 controls, showing deregulation of 35 mirnas. |
2014-06-03 |
2023-08-12 |
Not clear |
| Young-Je Si. Treadmill exercise alleviates impairment of spatial learning ability through enhancing cell proliferation in the streptozotocin-induced Alzheimer's disease rats. Journal of exercise rehabilitation. vol 10. issue 2. 2014-05-30. PMID:24877042. |
decreased cell proliferation with decrement of bdnf and trkb expressions in the hippocampus were observed in the stz-induced alzheimer's disease rats. |
2014-05-30 |
2023-08-13 |
rat |
| Vanessa A Guzman, Owen T Carmichael, Christopher Schwarz, Giuseppe Tosto, Molly E Zimmerman, Adam M Brickma. White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 9. issue 5 Suppl. 2014-05-28. PMID:23375566. |
current hypothetical models of alzheimer's disease (ad) pathogenesis emphasize the role of β-amyloid (aβ), tau deposition, and neurodegenerative changes in the mesial temporal lobe, particularly the entorhinal cortex and hippocampus. |
2014-05-28 |
2023-08-12 |
Not clear |
| Vanessa A Guzman, Owen T Carmichael, Christopher Schwarz, Giuseppe Tosto, Molly E Zimmerman, Adam M Brickma. White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 9. issue 5 Suppl. 2014-05-28. PMID:23375566. |
we used data from the alzheimer's disease neuroimaging initiative (adni) to (1) confirm whether entorhinal cortex and hippocampal volume are associated with memory among individuals with amnestic mild cognitive impairment (mci) who are at risk for ad; and (2) determine whether regional white matter hyperintensity (wmh) volume, a radiological marker of small-vessel cerebrovascular disease, is associated with entorhinal cortex and hippocampal volume independent of putative ad biomarkers in this group. |
2014-05-28 |
2023-08-12 |
Not clear |
| Egidio D'Angelo, Paolo Mazzarell. MRI observation of hippocampal degeneration in Alzheimer's disease: a forgotten case. Functional neurology. vol 28. issue 3. 2014-05-28. PMID:24139660. |
mri observation of hippocampal degeneration in alzheimer's disease: a forgotten case. |
2014-05-28 |
2023-08-12 |
Not clear |
| Egidio D'Angelo, Paolo Mazzarell. MRI observation of hippocampal degeneration in Alzheimer's disease: a forgotten case. Functional neurology. vol 28. issue 3. 2014-05-28. PMID:24139660. |
at the beginning of the 1990s, as part of work being done for a master's degree thesis in physics, an important observation of hippocampal degeneration in alzheimer's disease was made in pavia. |
2014-05-28 |
2023-08-12 |
Not clear |
| J B Pereira, L Cavallin, G Spulber, C Aguilar, P Mecocci, B Vellas, M Tsolaki, I Kłoszewska, H Soininen, C Spenger, D Aarsland, S Lovestone, A Simmons, L-O Wahlund, E Westma. Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut-offs. Journal of internal medicine. vol 275. issue 3. 2014-05-26. PMID:24118559. |
visual assessment of medial temporal lobe atrophy (mta; range 0-4, from no atrophy to increasing atrophy of the choroid fissure, temporal horns and hippocampus) is a sensitive radiological marker of alzheimer's disease (ad). |
2014-05-26 |
2023-08-12 |
Not clear |
| Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Alexandre Bejanin, Stéphanie Egret, Alice Pélerin, Florence Mézenge, Serge Belliard, Vincent de La Sayette, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer's and semantic dementia-targeted networks. Neuron. vol 81. issue 6. 2014-05-21. PMID:24656258. |
intrinsic connectivity identifies the hippocampus as a main crossroad between alzheimer's and semantic dementia-targeted networks. |
2014-05-21 |
2023-08-12 |
Not clear |