| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Orta-Salazar, C A Cuellar-Lemus, S Díaz-Cintra, A I Feria-Velasc. Cholinergic markers in the cortex and hippocampus of some animal species and their correlation to Alzheimer's disease. Neurologia (Barcelona, Spain). vol 29. issue 8. 2016-02-25. PMID:23433740. |
cholinergic markers in the cortex and hippocampus of some animal species and their correlation to alzheimer's disease. |
2016-02-25 |
2023-08-12 |
Not clear |
| Zhiren Wang, Yali Wang, Bo Wang, Wenrui Li, Ling Huang, Xingshu L. Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer's Disease. Journal of medicinal chemistry. vol 58. issue 21. 2016-02-25. PMID:26473791. |
most importantly, oral administration of 18d·hcl demonstrated marked improvements in cognitive and spatial memory in a rat model of alzheimer's disease and protected hippocampal neurons from necrosis. |
2016-02-25 |
2023-08-13 |
rat |
| Per Selnes, Ramune Grambaite, Mariano Rincon, Atle Bjørnerud, Leif Gjerstad, Erik Hessen, Eirik Auning, Krisztina Johansen, Ina S Almdahl, Paulina Due-Tønnessen, Kjetil Vegge, Börje Bjelke, Tormod Fladb. Hippocampal complex atrophy in poststroke and mild cognitive impairment. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 35. issue 11. 2016-02-16. PMID:26036934. |
to investigate putative interacting or distinct pathways for hippocampal complex substructure (hcs) atrophy and cognitive affection in early-stage alzheimer's disease (ad) and cerebrovascular disease (cvd), we recruited healthy controls, patients with mild cognitive impairment (mci) and poststroke patients. |
2016-02-16 |
2023-08-13 |
Not clear |
| Geert Jan Biessels, Lawrence P Reaga. Hippocampal insulin resistance and cognitive dysfunction. Nature reviews. Neuroscience. vol 16. issue 11. 2016-02-10. PMID:26462756. |
animal models of ir help to bridge these gaps and point to hippocampal ir as a potential mediator of cognitive dysfunction in t2dm, as well as in alzheimer disease (ad). |
2016-02-10 |
2023-08-13 |
Not clear |
| Giovanna Giuseppina Altobelli, Donatella Cimini, Giuseppe Esposito, Teresa Iuvone, Vincenzo Cimin. Analysis of calretinin early expression in the rat hippocampus after beta amyloid (1-42) peptide injection. Brain research. vol 1610. 2016-02-09. PMID:25813826. |
we carried out quantitative analysis of the transient changes in calretinin expression shown by hybridochemistry within neuronal cell populations in the hippocampus of a beta amyloid-treated rat model of alzheimer's disease and their correlation with endocannabinoid increase. |
2016-02-09 |
2023-08-13 |
rat |
| Amit Pal, Rajendra Prasa. Regional Distribution of Copper, Zinc and Iron in Brain of Wistar Rat Model for Non-Wilsonian Brain Copper Toxicosis. Indian journal of clinical biochemistry : IJCB. vol 31. issue 1. 2016-02-09. PMID:26855494. |
in previous studies, we have reported first in vivo evidence of copper deposition in the choroid plexus, cognitive impairments, astrocytes swelling (alzheimer type ii cells) and astrogliosis (increase in number of astrocytes), and degenerated neurons coupled with significant increase in the hippocampus copper and zinc content in copper-intoxicated wistar rats. |
2016-02-09 |
2023-08-13 |
rat |
| Fen Guo, Xin-Yi Li, Xiao-Hui Wang, Jin-Shun Q. [Involvement of protein tyrosine kinases in β-amyloid protein-induced suppression of long-term potentiation in the rat hippocampal CA1 region in vivo]. Sheng li xue bao : [Acta physiologica Sinica]. vol 61. issue 3. 2016-02-02. PMID:19536439. |
injection of aβ(23-35) can significantly suppress the hfs-induced ltp in the ca1 area of rat hippocampus in vivo, implying that the aβ deposited in the brain of patients with alzheimer's disease may impair the function of learning and memory by suppressing the hippocampal ltp. |
2016-02-02 |
2023-08-12 |
rat |
| Shu-Zhi Zhong, Shi-Ping ma, Zong-Yuan Hon. [Peoniflorin activates Nrf2/ARE pathway to alleviate the Abeta(1-42)-induced hippocampal neuron injury in rats]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 48. issue 8. 2016-02-02. PMID:24187848. |
this study was to investigate the effect of peoniflorin on the expressions of nuclear factor erythroid 2-related factor 2 (nrf2) and its downstream signal molecules in the hippocampus of alzheimer's disease (ad) rats for exploring the mechanism of peoniflorin protecting hippocampal neurons. |
2016-02-02 |
2023-08-12 |
rat |
| Charlotte Bezzina, Laure Verret, Cécile Juan, Jessica Remaud, Hélène Halley, Claire Rampon, Lionel Daha. Early onset of hypersynchronous network activity and expression of a marker of chronic seizures in the Tg2576 mouse model of Alzheimer's disease. PloS one. vol 10. issue 3. 2016-02-02. PMID:25768013. |
cortical and hippocampal hypersynchrony of neuronal networks seems to be an early event in alzheimer's disease pathogenesis. |
2016-02-02 |
2023-08-13 |
mouse |
| Mingzhen Tan, Anqi Qi. Spectral Laplace-Beltrami wavelets with applications in medical images. IEEE transactions on medical imaging. vol 34. issue 5. 2016-02-01. PMID:25343758. |
second, we show that multi-resolutional capabilities of the proposed framework are applicable in the classification of alzheimer's patients with normal subjects using hippocampal shapes. |
2016-02-01 |
2023-08-13 |
human |
| Keith A Josephs, Jennifer L Whitwell, Nirubol Tosakulwong, Stephen D Weigand, Melissa E Murray, Amanda M Liesinger, Leonard Petrucelli, Matthew L Senjem, Robert J Ivnik, Joseph E Parisi, Ronald C Petersen, Dennis W Dickso. TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features. Annals of neurology. vol 78. issue 5. 2016-02-01. PMID:26224156. |
the aim of this study was to determine whether the frequency of tar dna-binding protein 43 (tdp-43) deposition in alzheimer's disease (ad) differs across pathologically defined ad subtypes (hippocampal sparing [hpsp]; typical and limbic) and further examine the relationship between tdp-43, pathological subtype, and clinical features in ad. |
2016-02-01 |
2023-08-13 |
Not clear |
| Petr Bednařík, Amir Moheet, Dinesh K Deelchand, Uzay E Emir, Lynn E Eberly, Martin Bareš, Elizabeth R Seaquist, Gülin Ö. Feasibility and reproducibility of neurochemical profile quantification in the human hippocampus at 3 T. NMR in biomedicine. vol 28. issue 6. 2016-01-29. PMID:25904240. |
hippocampal dysfunction is known to be associated with several neurological and neuropsychiatric disorders such as alzheimer's disease, epilepsy, schizophrenia and depression; therefore, there has been significant clinical interest in studying hippocampal neurochemistry. |
2016-01-29 |
2023-08-13 |
human |
| Lorenzo Pasquini, Martin Scherr, Masoud Tahmasian, Chun Meng, Nicholas E Myers, Marion Ortner, Mark Mühlau, Alexander Kurz, Hans Förstl, Claus Zimmer, Timo Grimmer, Afra M Wohlschläger, Valentin Riedl, Christian Sor. Link between hippocampus' raised local and eased global intrinsic connectivity in AD. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 11. issue 5. 2016-01-28. PMID:25043909. |
the hippocampus (hp) is part of the default mode network (dmn), and both are key targets of alzheimer's disease (ad). |
2016-01-28 |
2023-08-13 |
Not clear |
| María José Delgado-Cortés, Ana M Espinosa-Oliva, Manuel Sarmiento, Sandro Argüelles, Antonio J Herrera, Raquel Mauriño, Ruth F Villarán, José L Venero, Alberto Machado, Rocío M de Pablo. Synergistic deleterious effect of chronic stress and sodium azide in the mouse hippocampus. Chemical research in toxicology. vol 28. issue 4. 2016-01-22. PMID:25658758. |
we found that chronic stress increases the levels of several proteins involved in alzheimer's disease pathogenesis, such as presenilin 1, presenilin 2, and s100β, besides inducing the aggregation of tau, ubiquitin, and β-amyloid proteins in the hippocampus. |
2016-01-22 |
2023-08-13 |
mouse |
| María José Delgado-Cortés, Ana M Espinosa-Oliva, Manuel Sarmiento, Sandro Argüelles, Antonio J Herrera, Raquel Mauriño, Ruth F Villarán, José L Venero, Alberto Machado, Rocío M de Pablo. Synergistic deleterious effect of chronic stress and sodium azide in the mouse hippocampus. Chemical research in toxicology. vol 28. issue 4. 2016-01-22. PMID:25658758. |
our results point out that chronic stress is a risk factor contributing to amplify and accelerate alzheimer's disease features in the hippocampus. |
2016-01-22 |
2023-08-13 |
mouse |
| Fenglei Chao, Lei Zhang, Yanmin Luo, Qian Xiao, Fulin Lv, Qi He, Chunni Zhou, Yi Zhang, Lin Jiang, Rong Jiang, Hengwei Gu, Yong Tan. Running Exercise Reduces Myelinated Fiber Loss in the Dentate Gyrus of the Hippocampus in APP/PS1 Transgenic Mice. Current Alzheimer research. vol 12. issue 4. 2016-01-20. PMID:25817255. |
to investigate the effect of running exercise on myelinated fibers in the dentate gyrus (dg) of the hippocampus during alzheimer's disease (ad), 6-month-old male app/ps1 transgenic mice were randomly assigned to control or running groups. |
2016-01-20 |
2023-08-13 |
mouse |
| Ailin Song, Jingwen Yan, Sungeun Kim, Shannon Leigh Risacher, Aaron K Wong, Andrew J Saykin, Li Shen, Casey S Green. Network-based analysis of genetic variants associated with hippocampal volume in Alzheimer's disease: a study of ADNI cohorts. BioData mining. vol 9. 2016-01-20. PMID:26788126. |
network-based analysis of genetic variants associated with hippocampal volume in alzheimer's disease: a study of adni cohorts. |
2016-01-20 |
2023-08-13 |
Not clear |
| Xiao Wang, Jinhui Wang, Yi He, Huiying Li, Huishu Yuan, Alan Evans, Xin Yu, Yong He, Huali Wan. Apolipoprotein E ε4 Modulates Cognitive Profiles, Hippocampal Volume, and Resting-State Functional Connectivity in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 45. issue 3. 2016-01-19. PMID:25624419. |
apolipoprotein e ε4 modulates cognitive profiles, hippocampal volume, and resting-state functional connectivity in alzheimer's disease. |
2016-01-19 |
2023-08-13 |
Not clear |
| Peng Zhang, Wen Qin, Dawei Wang, Bing Liu, Yunting Zhang, Tianzi Jiang, Chunshui Y. Impacts of PICALM and CLU variants associated with Alzheimer's disease on the functional connectivity of the hippocampus in healthy young adults. Brain structure & function. vol 220. issue 3. 2016-01-15. PMID:24578178. |
impacts of picalm and clu variants associated with alzheimer's disease on the functional connectivity of the hippocampus in healthy young adults. |
2016-01-15 |
2023-08-12 |
human |
| Kyung-Ok Uhm, Mi-Jeong Kim, Makoto Kawaguchi, Hiroyasu Akatsu, Yutaka Miura, Sachiyo Misumi, Hideki Hida, Eun-Kyoung Choi, Yong-Sun Kim, Makoto Michikawa, Cha-Gyun Jun. ATBF1 is a novel amyloid-β protein precursor (AβPP) binding protein that affects AβPP expression. Journal of Alzheimer's disease : JAD. vol 43. issue 1. 2016-01-15. PMID:25079792. |
here, we show that atbf1 levels are increased in the cytoplasm of hippocampal neurons in alzheimer's disease (ad) brains compared with non-ad brains. |
2016-01-15 |
2023-08-13 |
mouse |