| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kathy C Richards, Nalaka Gooneratne, Barry Dicicco, Alexandra Hanlon, Stephen Moelter, Fannie Onen, Yanyan Wang, Amy Sawyer, Terri Weaver, Alicia Lozano, Patricia Carter, Jerry Johnso. CPAP Adherence May Slow 1-Year Cognitive Decline in Older Adults with Mild Cognitive Impairment and Apnea. Journal of the American Geriatrics Society. vol 67. issue 3. 2020-03-18. PMID:30724333. |
obstructive sleep apnea (osa) has been linked to an increased risk for alzheimer's disease (ad), but little prospective evidence exists on the effects of osa treatment in preclinical ad. |
2020-03-18 |
2023-08-13 |
Not clear |
| Yo-El S Ju, Margaret A Zangrilli, Mary Beth Finn, Anne M Fagan, David M Holtzma. Obstructive sleep apnea treatment, slow wave activity, and amyloid-β. Annals of neurology. vol 85. issue 2. 2020-01-06. PMID:30597615. |
obstructive sleep apnea (osa) increases risk of dementia, a relationship that may be mediated by amyloid-β (aβ) and downstream alzheimer disease pathology. |
2020-01-06 |
2023-08-13 |
human |
| Jae Hoon Cho, Jeffrey D Suh, Kyung-Do Han, Jin-Hyung Jung, Heung Man Le. Uvulopalatopharyngoplasty May Reduce the Incidence of Dementia Caused by Obstructive Sleep Apnea: National Insurance Service Survey 2007-2014. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 14. issue 10. 2019-11-19. PMID:30353808. |
numerous studies have found that obstructive sleep apnea (osa) causes or exacerbates dementia, including alzheimer disease and vascular dementia. |
2019-11-19 |
2023-08-13 |
Not clear |
| M Aaron Guest, Margaret C Miller, Macie P Smith, Brenda Hylema. Office for the Study of Aging at the University of South Carolina: Promoting Healthy Aging Through Program Development, Evaluation, Education/Training, and Research for South Carolina's Older Adults. Journal of applied gerontology : the official journal of the Southern Gerontological Society. vol 37. issue 3. 2019-11-05. PMID:27075373. |
the office for the study of aging (osa) at the university of south carolina was established in 1988 in conjunction with the founding of the south carolina alzheimer's disease registry. |
2019-11-05 |
2023-08-13 |
Not clear |
| Alby Elias, Tia Cummins, Regan Tyrrell, Fiona Lamb, Vincent Dore, Robert Williams, J V Rosenfeld, Malcolm Hopwood, Victor L Villemagne, Christopher C Row. Risk of Alzheimer's Disease in Obstructive Sleep Apnea Syndrome: Amyloid-β and Tau Imaging. Journal of Alzheimer's disease : JAD. vol 66. issue 2. 2019-10-08. PMID:30320587. |
an association between obstructive sleep apnea (osa) and alzheimer's disease has been suggested but little is known about amyloid-β and tau deposition in this syndrome. |
2019-10-08 |
2023-08-13 |
Not clear |
| Ram A Sharma, Andrew W Varga, Omonigho M Bubu, Elizabeth Pirraglia, Korey Kam, Ankit Parekh, Margaret Wohlleber, Margo D Miller, Andreia Andrade, Clifton Lewis, Samuel Tweardy, Maja Buj, Po L Yau, Reem Sadda, Lisa Mosconi, Yi Li, Tracy Butler, Lidia Glodzik, Els Fieremans, James S Babb, Kaj Blennow, Henrik Zetterberg, Shou E Lu, Sandra G Badia, Sergio Romero, Ivana Rosenzweig, Nadia Gosselin, Girardin Jean-Louis, David M Rapoport, Mony J de Leon, Indu Ayappa, Ricardo S Osori. Obstructive Sleep Apnea Severity Affects Amyloid Burden in Cognitively Normal Elderly. A Longitudinal Study. American journal of respiratory and critical care medicine. vol 197. issue 7. 2019-08-19. PMID:29125327. |
recent evidence suggests that obstructive sleep apnea (osa) may be a risk factor for developing mild cognitive impairment and alzheimer's disease. |
2019-08-19 |
2023-08-13 |
Not clear |
| Andreia G Andrade, Omonigho M Bubu, Andrew W Varga, Ricardo S Osori. The Relationship between Obstructive Sleep Apnea and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 64. issue s1. 2019-06-11. PMID:29782319. |
obstructive sleep apnea (osa) and alzheimer's disease (ad) are highly prevalent conditions with growing impact on our aging society. |
2019-06-11 |
2023-08-13 |
Not clear |
| Chang-Ho Yun, Ho-Young Lee, Seung Ku Lee, Hyun Kim, Hyung Suk Seo, Seong Ae Bang, Sang Eun Kim, Douglas N Greve, Rhoda Au, Chol Shin, Robert J Thoma. Amyloid Burden in Obstructive Sleep Apnea. Journal of Alzheimer's disease : JAD. vol 59. issue 1. 2018-04-06. PMID:28550245. |
to test the hypothesis that excessive amyloid deposition is a biological link between obstructive sleep apnea (osa) and alzheimer's disease, we determined whether osa increases cerebral amyloid burden, relative to controls, using pittsburgh compound b (pib) pet imaging. |
2018-04-06 |
2023-08-13 |
human |
| Chang-Ho Yun, Ho-Young Lee, Seung Ku Lee, Hyun Kim, Hyung Suk Seo, Seong Ae Bang, Sang Eun Kim, Douglas N Greve, Rhoda Au, Chol Shin, Robert J Thoma. Amyloid Burden in Obstructive Sleep Apnea. Journal of Alzheimer's disease : JAD. vol 59. issue 1. 2018-04-06. PMID:28550245. |
the study suggests that osa accelerates amyloid deposition and may contribute to the development or progression of alzheimer's disease. |
2018-04-06 |
2023-08-13 |
human |
| Claudio Liguori, Nicola Biagio Mercuri, Francesca Izzi, Andrea Romigi, Alberto Cordella, Giuseppe Sancesario, Fabio Placid. Obstructive Sleep Apnea is Associated With Early but Possibly Modifiable Alzheimer's Disease Biomarkers Changes. Sleep. vol 40. issue 5. 2017-11-02. PMID:28329084. |
the, literature lacks studies examining sleep, cognition, and alzheimer's disease (ad) cerebrospinal fluid (csf) biomarkers in osa patients. |
2017-11-02 |
2023-08-13 |
Not clear |
| Yo-El S Ju, Mary Beth Finn, Courtney L Sutphen, Elizabeth M Herries, Gina M Jerome, Jack H Ladenson, Daniel L Crimmins, Anne M Fagan, David M Holtzma. Obstructive sleep apnea decreases central nervous system-derived proteins in the cerebrospinal fluid. Annals of neurology. vol 80. issue 1. 2017-06-13. PMID:27129429. |
we hypothesized that one mechanism underlying the association between obstructive sleep apnea (osa) and alzheimer's disease is osa leading to decreased slow wave activity (swa), increased synaptic activity, decreased glymphatic clearance, and increased amyloid-β. |
2017-06-13 |
2023-08-13 |
Not clear |
| Leila Kheirandish-Gozal, Mona F Philby, María Luz Alonso-Álvarez, Joaquin Terán-Santos, David Goza. Biomarkers of Alzheimer Disease in Children with Obstructive Sleep Apnea: Effect of Adenotonsillectomy. Sleep. vol 39. issue 6. 2017-05-22. PMID:27070140. |
both osa and obesity (ob) have been associated with increased risk for alzheimer disease (ad). |
2017-05-22 |
2023-08-13 |
Not clear |
| Ivana Rosenzweig, Martin Glasser, William R Crum, Matthew J Kempton, Milan Milosevic, Alison McMillan, Guy D Leschziner, Veena Kumari, Peter Goadsby, Anita K Simonds, Steve C R Williams, Mary J Morrel. Changes in Neurocognitive Architecture in Patients with Obstructive Sleep Apnea Treated with Continuous Positive Airway Pressure. EBioMedicine. vol 7. 2017-03-06. PMID:27322475. |
obstructive sleep apnea (osa) is a chronic, multisystem disorder that has a bidirectional relationship with several major neurological disorders, including alzheimer's dementia. |
2017-03-06 |
2023-08-13 |
Not clear |
| Farnoosh Emamian, Habibolah Khazaie, Masoud Tahmasian, Guy D Leschziner, Mary J Morrell, Ging-Yuek R Hsiung, Ivana Rosenzweig, Amir A Sepehr. The Association Between Obstructive Sleep Apnea and Alzheimer's Disease: A Meta-Analysis Perspective. Frontiers in aging neuroscience. vol 8. 2016-05-05. PMID:27148046. |
alzheimer's disease (ad) and obstructive sleep apnea (osa) are highly prevalent, chronic conditions with intriguing, yet poorly understood epidemiological overlap. |
2016-05-05 |
2023-08-13 |
Not clear |
| Weihong Pan, Abba J Kasti. Can sleep apnea cause Alzheimer's disease? Neuroscience and biobehavioral reviews. vol 47. 2015-08-07. PMID:25451764. |
both obstructive sleep apnea (osa) and alzheimer's disease (ad) are increasing health concerns. |
2015-08-07 |
2023-08-13 |
Not clear |
| Kinga Szigeti, Blanka Kellermayer, Jenna M Lentini, Brian Trummer, Deepika Lal, Rachelle S Doody, Li Yan, Song Liu, Changxing M. Ordered subset analysis of copy number variation association with age at onset of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 4. 2015-03-30. PMID:24787912. |
we hypothesized that in a genetically heterogeneous disorder such as alzheimer's disease (ad), utilizing osa by age at onset (aao) of ad may increase the power to detect relevant loci. |
2015-03-30 |
2023-08-13 |
human |
| Satomi Shiota, Hidenori Takekawa, Shin-Ei Matsumoto, Kazuya Takeda, Fariz Nurwidya, Yasuko Yoshioka, Fumiyuki Takahashi, Nobutaka Hattori, Takeshi Tabira, Hideki Mochizuki, Kazuhisa Takahash. Chronic intermittent hypoxia/reoxygenation facilitate amyloid-β generation in mice. Journal of Alzheimer's disease : JAD. vol 37. issue 2. 2014-04-15. PMID:23948880. |
previous studies have shown a high prevalence of obstructive sleep apnea (osa) among patients with alzheimer's disease (ad). |
2014-04-15 |
2023-08-12 |
mouse |
| Xiu-Hong Yang, Hui-Guo Liu, Xue Liu, Jun-Nan Che. Thioredoxin and impaired spatial learning and memory in the rats exposed to intermittent hypoxia. Chinese medical journal. vol 125. issue 17. 2013-05-17. PMID:22932184. |
obstructive sleep apnea (osa) can cause cognitive dysfunction and may be a reversible cause of cognitive loss in patients with alzheimer's disease (ad). |
2013-05-17 |
2023-08-12 |
rat |
| Lucia Sukys-Claudino, Walter Moraes, Christian Guilleminault, Sergio Tufik, Dalva Poyare. Beneficial effect of donepezil on obstructive sleep apnea: a double-blind, placebo-controlled clinical trial. Sleep medicine. vol 13. issue 3. 2012-07-10. PMID:22281004. |
previous publications have shown beneficial effects of cholinergic medication on obstructive sleep apnea (osa) in alzheimer's disease (ad) patients. |
2012-07-10 |
2023-08-12 |
Not clear |
| Jana R Cooke, Sonia Ancoli-Israel, Lianqi Liu, Jose S Loredo, Loki Natarajan, Barton S Palmer, Feng He, Jody Corey-Bloo. Continuous positive airway pressure deepens sleep in patients with Alzheimer's disease and obstructive sleep apnea. Sleep medicine. vol 10. issue 10. 2010-02-24. PMID:19699148. |
patients with alzheimer's disease (ad) and obstructive sleep apnea (osa) experience disrupted sleep. |
2010-02-24 |
2023-08-12 |
Not clear |