Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
N Gervaise, H Combe, P Lecomt. [Acromegaly in 2000]. Annales d'endocrinologie. vol 61. issue 3. 2000-11-13. PMID:10970950. |
the therapeutic strategy for acromegaly is thus changing with the advent of somatostatin agonists. |
2000-11-13 |
2023-08-12 |
Not clear |
K Suyama, D Uchida, T Tanaka, J Saito, Y Noguchi, S Nakamura, I Tatsuno, Y Saito, N Saek. Octreotide improved ventricular arrhythmia in an acromegalic patient. Endocrine journal. vol 47 Suppl. 2000-10-25. PMID:10890189. |
we saw a remarkable effect of octreotide, the long-acting somatostatin analogue, in reducing the number of ventricular premature complexes (vpcs) in a 59-year-old woman with acromegaly. |
2000-10-25 |
2023-08-12 |
Not clear |
A Colao, P Marzullo, D Ferone, L Spinelli, A Cuocolo, D Bonaduce, M Salvatore, V Boerlin, I Lancranjan, G Lombard. Cardiovascular effects of depot long-acting somatostatin analog Sandostatin LAR in acromegaly. The Journal of clinical endocrinology and metabolism. vol 85. issue 9. 2000-10-16. PMID:10999798. |
cardiovascular effects of depot long-acting somatostatin analog sandostatin lar in acromegaly. |
2000-10-16 |
2023-08-12 |
Not clear |
A Colao, P Marzullo, D Ferone, L Spinelli, A Cuocolo, D Bonaduce, M Salvatore, V Boerlin, I Lancranjan, G Lombard. Cardiovascular effects of depot long-acting somatostatin analog Sandostatin LAR in acromegaly. The Journal of clinical endocrinology and metabolism. vol 85. issue 9. 2000-10-16. PMID:10999798. |
the aim of the present study was to investigate the early effect of oct-lar treatment on the left ventricular (lv) structure and performance in 15 somatostatin analog-naive patients with acromegaly (gh, 94.8 +/- 24.9 mu/l; igf-i, 757.9 +/- 66.6 microg/l), focusing on the early effect of gh and igf-i suppression on the heart. |
2000-10-16 |
2023-08-12 |
Not clear |
M Thanou, J C Verhoef, P Marbach, H E Junginge. Intestinal absorption of octreotide: N-trimethyl chitosan chloride (TMC) ameliorates the permeability and absorption properties of the somatostatin analogue in vitro and in vivo. Journal of pharmaceutical sciences. vol 89. issue 7. 2000-09-20. PMID:10861597. |
octreotide acetate is a somatostatin analogue used for the control of endocrine tumors of the gastrointestinal (gi) tract and the treatment of acromegaly. |
2000-09-20 |
2023-08-12 |
rat |
F Manelli, S Bossoni, A Burattin, M Doga, S B Solerte, G Romanelli, A Giustin. Exercise-induced microalbuminuria in patients with active acromegaly: acute effects of slow-release lanreotide, a long-acting somatostatin analog. Metabolism: clinical and experimental. vol 49. issue 5. 2000-06-08. PMID:10831175. |
exercise-induced microalbuminuria in patients with active acromegaly: acute effects of slow-release lanreotide, a long-acting somatostatin analog. |
2000-06-08 |
2023-08-12 |
human |
F Manelli, S Bossoni, A Burattin, M Doga, S B Solerte, G Romanelli, A Giustin. Exercise-induced microalbuminuria in patients with active acromegaly: acute effects of slow-release lanreotide, a long-acting somatostatin analog. Metabolism: clinical and experimental. vol 49. issue 5. 2000-06-08. PMID:10831175. |
the aim of our study was to evaluate the acute short-term effects of slow-release lanreotide (sr-l), a long-acting somatostatin analog, on uae and alpha1-microglobulinuria (a-1-m), a marker of renal tubular damage, at rest and after exercise in 7 normotensive patients with active acromegaly and normal renal function (4 males and 3 females; mean age, 53 +/- 3.1 years; body mass index [bmi], 27.3 +/- 1.1 kg/m2) at baseline and 7 and 14 days after sr-l injection (30 mg). |
2000-06-08 |
2023-08-12 |
human |
H E Turner, A Vadivale, J Keenan, J A Was. A comparison of lanreotide and octreotide LAR for treatment of acromegaly. Clinical endocrinology. vol 51. issue 3. 2000-05-09. PMID:10469005. |
two long-acting depot somatostatin analogues have recently been licensed for the treatment of acromegaly. |
2000-05-09 |
2023-08-12 |
Not clear |
R Waśko, M Ruchała, J Sawicka, M Kotwicka, W Liebert, J Sowińsk. Short-term pre-surgical treatment with somatostatin analogues, octreotide and lanreotide, in acromegaly. Journal of endocrinological investigation. vol 23. issue 1. 2000-04-07. PMID:10698045. |
short-term pre-surgical treatment with somatostatin analogues, octreotide and lanreotide, in acromegaly. |
2000-04-07 |
2023-08-12 |
Not clear |
R Waśko, M Ruchała, J Sawicka, M Kotwicka, W Liebert, J Sowińsk. Short-term pre-surgical treatment with somatostatin analogues, octreotide and lanreotide, in acromegaly. Journal of endocrinological investigation. vol 23. issue 1. 2000-04-07. PMID:10698045. |
eighteen patients with symptoms of active acromegaly were treated with somatostatin analogues for 4 weeks before surgery. |
2000-04-07 |
2023-08-12 |
Not clear |
R Waśko, M Ruchała, J Sawicka, M Kotwicka, W Liebert, J Sowińsk. Short-term pre-surgical treatment with somatostatin analogues, octreotide and lanreotide, in acromegaly. Journal of endocrinological investigation. vol 23. issue 1. 2000-04-07. PMID:10698045. |
the same tests were performed on ten control patients with clinically and biochemically active acromegaly, subjected to surgery but not treated with somatostatin analogues. |
2000-04-07 |
2023-08-12 |
Not clear |
J J Orrego, A L Barka. Pituitary disorders. Drug treatment options. Drugs. vol 59. issue 1. 2000-03-28. PMID:10718101. |
somatostatin analogues have also shown efficacy in patients with acromegaly who have not responded to surgery or in patients with tsh-secreting adenomas who have not improved with surgery and radiotherapy. |
2000-03-28 |
2023-08-12 |
Not clear |
P Jaquet, A Saveanu, G Gunz, F Fina, A J Zamora, M Grino, M D Culler, J P Moreau, A Enjalbert, L H Ouafi. Human somatostatin receptor subtypes in acromegaly: distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes. The Journal of clinical endocrinology and metabolism. vol 85. issue 2. 2000-03-09. PMID:10690891. |
human somatostatin receptor subtypes in acromegaly: distinct patterns of messenger ribonucleic acid expression and hormone suppression identify different tumoral phenotypes. |
2000-03-09 |
2023-08-12 |
human |
J L Sadou. [Somatotrope pituitary adenomas. Contribution of presurgical treatment with somatostatin analogs]. Annales d'endocrinologie. vol 60. issue 6. 2000-02-10. PMID:10617802. |
presurgical treatment of somatotrope pituitary adenomas with somatostatin analogs is warranted by the efficacy of both octreotide and lanreotide in the treatment of acromegaly. |
2000-02-10 |
2023-08-12 |
Not clear |
J L Sadou. [Somatotrope pituitary adenomas. Contribution of presurgical treatment with somatostatin analogs]. Annales d'endocrinologie. vol 60. issue 6. 2000-02-10. PMID:10617802. |
excepting encased microadenomas and macroademonmas, all patients with acromegaly should be given somatostatin analogs preoperatively. |
2000-02-10 |
2023-08-12 |
Not clear |
R Cozzi, D Dallabonzana, R Attanasio, M Barausse, G Oppizz. A comparison between octreotide-LAR and lanreotide-SR in the chronic treatment of acromegaly. European journal of endocrinology. vol 141. issue 3. 1999-11-12. PMID:10474124. |
at present long-acting somatostatin analogs represent the first-line medical treatment of acromegaly. |
1999-11-12 |
2023-08-12 |
Not clear |
J Mozas, E Ocón, M López de la Torre, A M Suárez, J A Miranda, A J Herruz. Successful pregnancy in a woman with acromegaly treated with somatostatin analog (octreotide) prior to surgical resection. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. vol 65. issue 1. 1999-09-20. PMID:10390105. |
successful pregnancy in a woman with acromegaly treated with somatostatin analog (octreotide) prior to surgical resection. |
1999-09-20 |
2023-08-12 |
Not clear |
M Suliman, R Jenkins, R Ross, T Powell, R Battersby, D R Culle. Long-term treatment of acromegaly with the somatostatin analogue SR-lanreotide. Journal of endocrinological investigation. vol 22. issue 6. 1999-09-20. PMID:10435849. |
long-term treatment of acromegaly with the somatostatin analogue sr-lanreotide. |
1999-09-20 |
2023-08-12 |
Not clear |
E Comets, F Mentré, F Nimmerfall, R Kawai, I Mueller, P Marbach, J Vondersche. Nonparametric analysis of the absorption profile of octreotide in rabbits from long-acting release formulation OncoLAR. Journal of controlled release : official journal of the Controlled Release Society. vol 59. issue 2. 1999-07-13. PMID:10332054. |
octreotide (octreotide-acetate, sandostatin(r)) is a somatostatin analogue, used in long-term treatment of acromegaly. |
1999-07-13 |
2023-08-12 |
rabbit |
P Dasgupta, A T Singh, R Mukherje. Antiproliferative and GH-inhibitory activity of chimeric peptides consisting of GHRP-6 and somatostatin. Biochemical and biophysical research communications. vol 259. issue 2. 1999-06-28. PMID:10362518. |
such potent gh-inhibitory chimeric peptides may be of potential importance in the therapy of acromegaly, as well as provide novel tools to study the regulation of gh secretion by ghrp and somatostatin. |
1999-06-28 |
2023-08-12 |
rat |