| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael S Racine, Ariel L Barka. Somatostatin analogs in medical treatment of acromegaly. Endocrine. vol 20. issue 3. 2003-12-12. PMID:12721507. |
somatostatin analogs in medical treatment of acromegaly. |
2003-12-12 |
2023-08-12 |
Not clear |
| Ann Danoff, David Kleinber. Somatostatin analogs as primary medical therapy for acromegaly. Endocrine. vol 20. issue 3. 2003-12-12. PMID:12721510. |
somatostatin analogs as primary medical therapy for acromegaly. |
2003-12-12 |
2023-08-12 |
Not clear |
| Ann Danoff, David Kleinber. Somatostatin analogs as primary medical therapy for acromegaly. Endocrine. vol 20. issue 3. 2003-12-12. PMID:12721510. |
therefore, somatostatin analogs have emerged as a rational first-line treatment for the appropriately selected patient with acromegaly. |
2003-12-12 |
2023-08-12 |
Not clear |
| Morton G Burt, Ken K Y H. Comparison of efficacy and tolerability of somatostatin analogs and other therapies for acromegaly. Endocrine. vol 20. issue 3. 2003-12-12. PMID:12721511. |
comparison of efficacy and tolerability of somatostatin analogs and other therapies for acromegaly. |
2003-12-12 |
2023-08-12 |
Not clear |
| Morton G Burt, Ken K Y H. Comparison of efficacy and tolerability of somatostatin analogs and other therapies for acromegaly. Endocrine. vol 20. issue 3. 2003-12-12. PMID:12721511. |
somatostatin analogs improve symptoms and signs of acromegaly in the majority, normalize igf- 1 in up to 60%, and result in tumor shrinkage in up to half of patients. |
2003-12-12 |
2023-08-12 |
Not clear |
| Roberto Baldelli, Claudia Battista, Frida Leonetti, Maria-Rosaria Ghiggi, Maria-Cristina Ribaudo, Antonella Paoloni, Eugenio D'Amico, Elisabetta Ferretti, Roberto Baratta, Antonio Liuzzi, Vincenzo Trischitta, Guido Tamburran. Glucose homeostasis in acromegaly: effects of long-acting somatostatin analogues treatment. Clinical endocrinology. vol 59. issue 4. 2003-11-20. PMID:14510913. |
glucose homeostasis in acromegaly: effects of long-acting somatostatin analogues treatment. |
2003-11-20 |
2023-08-12 |
Not clear |
| Roberto Baldelli, Claudia Battista, Frida Leonetti, Maria-Rosaria Ghiggi, Maria-Cristina Ribaudo, Antonella Paoloni, Eugenio D'Amico, Elisabetta Ferretti, Roberto Baratta, Antonio Liuzzi, Vincenzo Trischitta, Guido Tamburran. Glucose homeostasis in acromegaly: effects of long-acting somatostatin analogues treatment. Clinical endocrinology. vol 59. issue 4. 2003-11-20. PMID:14510913. |
somatostatin analogues, which are used for medical treatment of acromegaly, may exert different hormonal effects on glucose homeostasis. |
2003-11-20 |
2023-08-12 |
Not clear |
| David R Clemmons, Kazuo Chihara, Pamela U Freda, Ken K Y Ho, Anne Klibanski, Shlomo Melmed, Stephen M Shalet, Christian J Strasburger, Peter J Trainer, Michael O Thorne. Optimizing control of acromegaly: integrating a growth hormone receptor antagonist into the treatment algorithm. The Journal of clinical endocrinology and metabolism. vol 88. issue 10. 2003-11-12. PMID:14557452. |
pegvisomant is the most effective drug treatment for acromegaly in normalizing igf-i and producing a clinical response; it is the preferred agent in patients resistant to or intolerant of somatostatin analogs. |
2003-11-12 |
2023-08-12 |
Not clear |
| Marcello Delano Bronstein, Luiz Roberto Salgado, Nina Rosa de Castro Musolin. Medical management of pituitary adenomas: the special case of management of the pregnant woman. Pituitary. vol 5. issue 2. 2003-10-23. PMID:12675507. |
somatostatin analogs have been used in acromegaly even during pregnancy with uneventful outcomes, but their safety in pregnancy is not well established, yet. |
2003-10-23 |
2023-08-12 |
Not clear |
| Shlomo Melmed, Mary Lee Vance, Ariel L Barkan, Bengt-Ake Bengtsson, David Kleinberg, Anne Klibanski, Peter J Traine. Current status and future opportunities for controlling acromegaly. Pituitary. vol 5. issue 3. 2003-07-17. PMID:12812311. |
novel new therapies for acromegaly include the somatostatin analog, lanreotide, gamma knife radiosurgery, and pegvisomant, the first in its class of new gh receptor antagonists. |
2003-07-17 |
2023-08-12 |
Not clear |
| G Lombardi, A Colao, P Marzullo, B Biondi, E Palmieri, S Fazi. Improvement of left ventricular hypertrophy and arrhythmias after lanreotide-induced GH and IGF-I decrease in acromegaly. A prospective multi-center study. Journal of endocrinological investigation. vol 25. issue 11. 2003-07-01. PMID:12553557. |
we report the results of a prospective italian multi-center study of the effects of lanreotide, a slow-release somatostatin analog, on left ventricular morphology and function and on the prevalence of ventricular arrhythmic events in 19 patients with active, newly diagnosed, uncomplicated acromegaly. |
2003-07-01 |
2023-08-12 |
Not clear |
| J C Smith, H Lane, N Davies, L M Evans, J Cockcroft, M F Scanlon, J S Davie. The effects of depot long-acting somatostatin analog on central aortic pressure and arterial stiffness in acromegaly. The Journal of clinical endocrinology and metabolism. vol 88. issue 6. 2003-07-01. PMID:12788854. |
the effects of depot long-acting somatostatin analog on central aortic pressure and arterial stiffness in acromegaly. |
2003-07-01 |
2023-08-12 |
human |
| Nienke R Biermasz, Niels C van den Oever, Marijke Frölich, Alberto M Pereira Arias, Jan W A Smit, Johannes A Romijn, Ferdinand Roelfsem. Sandostatin LAR in acromegaly: a 6-week injection interval suppresses GH secretion as effectively as a 4-week interval. Clinical endocrinology. vol 58. issue 3. 2003-05-30. PMID:12608933. |
depot preparations of long-acting somatostatin analogues are being used increasingly in the treatment of gh hypersecretion in patients with acromegaly, either as primary treatment or as secondary treatment following incomplete surgery. |
2003-05-30 |
2023-08-12 |
Not clear |
| Mary Lee Vanc. Medical treatment of functional pituitary tumors. Neurosurgery clinics of North America. vol 14. issue 1. 2003-05-02. PMID:12690980. |
a somatostatin analogue is effective medical therapy for patients with acromegaly, and this is usually administered if there is persistent gh hypersecretion after surgical resection. |
2003-05-02 |
2023-08-12 |
Not clear |
| Steven W J Lamberts, Wouter W de Herder, Leo J Hoflan. Somatostatin analogs in the diagnosis and treatment of cancer. Trends in endocrinology and metabolism: TEM. vol 13. issue 10. 2003-04-30. PMID:12431842. |
somatostatin analogs, such as octreotide, bind predominantly to sst(2) and successfully control hormone hypersecretion in patients with acromegaly, islet cell tumors and carcinoids, and (temporary) control of tumor growth is often also seen. |
2003-04-30 |
2023-08-12 |
human |
| Emmanuelle Comets, France Mentré, Peter Grass, Ryosei Kawai, Peter Marbach, Jacky Vondersche. Population pharmacodynamic analysis of octreotide in acromegalic patients. Clinical pharmacology and therapeutics. vol 73. issue 1. 2003-02-12. PMID:12545148. |
octreotide is an octapeptide analog of somatostatin used to normalize growth hormone levels in acromegaly. |
2003-02-12 |
2023-08-12 |
Not clear |
| C Ronchi, P Epaminonda, V Cappiello, P Beck-Peccoz, M Arosi. Effects of two different somatostatin analogs on glucose tolerance in acromegaly. Journal of endocrinological investigation. vol 25. issue 6. 2002-12-30. PMID:12109620. |
effects of two different somatostatin analogs on glucose tolerance in acromegaly. |
2002-12-30 |
2023-08-12 |
human |
| C Ronchi, P Epaminonda, V Cappiello, P Beck-Peccoz, M Arosi. Effects of two different somatostatin analogs on glucose tolerance in acromegaly. Journal of endocrinological investigation. vol 25. issue 6. 2002-12-30. PMID:12109620. |
the aim of this study was to compare the effects of 2 somatostatin analogs on glucose metabolism, lanreotide slow release (l-sr) and octreotide long acting release (o-lar), in 10 patients with acromegaly (2 of whom with overt type 2 diabetes mellitus). |
2002-12-30 |
2023-08-12 |
human |
| John Ayuk, Susan E Stewart, Paul M Stewart, Michael C Sheppar. Long-term safety and efficacy of depot long-acting somatostatin analogs for the treatment of acromegaly. The Journal of clinical endocrinology and metabolism. vol 87. issue 9. 2002-10-03. PMID:12213862. |
long-term safety and efficacy of depot long-acting somatostatin analogs for the treatment of acromegaly. |
2002-10-03 |
2023-08-12 |
human |
| John Ayuk, Susan E Stewart, Paul M Stewart, Michael C Sheppar. Long-term safety and efficacy of depot long-acting somatostatin analogs for the treatment of acromegaly. The Journal of clinical endocrinology and metabolism. vol 87. issue 9. 2002-10-03. PMID:12213862. |
depot somatostatin analogs are now increasingly being prescribed as adjuvant and primary therapy for the treatment of acromegaly. |
2002-10-03 |
2023-08-12 |
human |