| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuo Zhang, Yi-Lin Li, Xiao-Peng Guo, Lu Gao, Yong Yao, Ren-Zhi Wang, Bing Xin. [Association of GH and IGF-1 Burden with Cardiac Structural and Functional Changes in Acromegaly Patients]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. vol 48. issue 3. 2019-05-29. PMID:28616920. |
to investigate the association of growth hormone (gh) and insulin-like growth factor (igf-1) burden with the cardiac structural and functional changes in acromegaly patients. |
2019-05-29 |
2023-08-13 |
Not clear |
| B S Yurekli, N O Kutbay, M Aksit, A Suner, I Y Simsir, S Seckiner, G U Kocabas, G Bozkaya, F Saygil. Acromegaly is associated with high fibroblast growth factor-21 levels. Journal of endocrinological investigation. vol 42. issue 1. 2019-05-29. PMID:29754168. |
we aimed to investigate fgf-21 levels in acromegaly which is characterized by excess gh levels and is associated with comorbidities and altered body composition. |
2019-05-29 |
2023-08-13 |
Not clear |
| M Demirpence, A Guler, H Yilmaz, A Sayin, Y Pekcevik, H Turkon, A Colak, E M Ari, B Aslanipour, G U Kocabas, M Cala. Is elevated urotensin II level a predictor for increased cardiovascular risk in subjects with acromegaly? Journal of endocrinological investigation. vol 42. issue 2. 2019-05-29. PMID:29804270. |
acromegaly is a rare disorder existed in the result of overproduction of growth hormone (gh). |
2019-05-29 |
2023-08-13 |
human |
| Ana Laura Espinosa de Los Monteros, Ernesto Sosa-Eroza, Baldomero Gonzalez, Victoria Mendoza, Moises Mercad. Prevalence, Clinical and Biochemical Spectrum, and Treatment Outcome of Acromegaly With Normal Basal GH at Diagnosis. The Journal of clinical endocrinology and metabolism. vol 103. issue 10. 2019-05-28. PMID:30060172. |
prevalence, clinical and biochemical spectrum, and treatment outcome of acromegaly with normal basal gh at diagnosis. |
2019-05-28 |
2023-08-13 |
Not clear |
| Pedro Marques, Márta Korbonit. Pseudoacromegaly. Frontiers in neuroendocrinology. vol 52. 2019-05-17. PMID:30448536. |
however, some patients with physical features resembling acromegaly - usually affecting the face and extremities -, or gigantism - accelerated growth/tall stature - will have no abnormalities in the gh axis. |
2019-05-17 |
2023-08-13 |
human |
| Mônica R Gadelha, Leandro Kasuki, Dawn S T Lim, Maria Fleseri. Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update. Endocrine reviews. vol 40. issue 1. 2019-05-15. PMID:30184064. |
incidence of mortality, its correlation with gh (cumulative exposure vs last value), and igf-i levels and the shift in the main cause of mortality in patients with acromegaly are also addressed. |
2019-05-15 |
2023-08-13 |
Not clear |
| Azusa Miyamoto, Yoshikazu Masuhiro, Taiichiro Seki, Shigemasa Hanazawa, Hajime Shib. A designed cell-penetrating human SOCS2 protein suppresses GH-dependent cancer cell proliferation. Bioscience, biotechnology, and biochemistry. vol 83. issue 2. 2019-04-03. PMID:30343638. |
suppressor of cytokine signaling (socs) 2, a negative regulator of growth hormone (gh) and insulin-like growth factor 1 (igf-1), which is associated with acromegaly and cancers, is a promising candidate molecule for treating various diseases. |
2019-04-03 |
2023-08-13 |
human |
| Anne Marie Hannon, Triona O'Shea, Claire A Thompson, Mark J Hannon, Rosemary Dineen, Aftab Khattak, James Gibney, Domhnall J O'Halloran, Steven Hunter, Christopher J Thompson, Mark Sherloc. Pregnancy in acromegaly is safe and is associated with improvements in IGF-1 concentrations. European journal of endocrinology. vol 180. issue 4. 2019-03-11. PMID:30620709. |
only 5/17 pregnancies had optimal biochemical control of acromegaly preconception, as defined by igf-1 concentration in the age-related reference level and plasma gh concentration of <2 μg/l. |
2019-03-11 |
2023-08-13 |
Not clear |
| Katharina Schilbach, Daniel S Olsson, Margaret C S Boguszewski, Martin Bidlingmaier, Gudmundur Johannsson, Jens-Otto Lunde Jørgense. Biomarkers of GH action in children and adults. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 40. 2018-11-14. PMID:29601998. |
this article will review biomarkers, surrogate endpoints and clinical endpoints related to gh treatment in children and adults as well as in acromegaly. |
2018-11-14 |
2023-08-13 |
human |
| Masanori Yonenaga, Shingo Fujio, Mika Habu, Hiroshi Arimura, Takaaki Hiwatari, Shunichi Tanaka, Yasuyuki Kinoshita, Hiroshi Hosoyama, Hirofumi Hirano, Kazunori Arit. Postoperative Changes in Metabolic Parameters of Patients with Surgically Controlled Acromegaly: Assessment of New Stringent Cure Criteria. Neurologia medico-chirurgica. vol 58. issue 4. 2018-10-31. PMID:29479042. |
we retrospectively assessed metabolic parameters, the body habitus, and other health-related parameters of 48 patients with surgically controlled acromegaly who met the cortina criteria [normalized insulin-like growth factor-1 (igf-1) level and nadir growth hormone (gh) level <1.0 ng/ml during postoperative oral glucose tolerance test]. |
2018-10-31 |
2023-08-13 |
Not clear |
| Pedro Marques, Rupert Spencer, Patrick J Morrison, Ian M Carr, Mary N Dang, David T Bonthron, Steven Hunter, Márta Korbonit. Cantú syndrome with coexisting familial pituitary adenoma. Endocrine. vol 59. issue 3. 2018-10-26. PMID:29327300. |
pseudoacromegaly describes conditions with an acromegaly related physical appearance without abnormalities in the growth hormone (gh) axis. |
2018-10-26 |
2023-08-13 |
Not clear |
| Ichiro Yamauchi, Yoriko Sakane, Takafumi Yamashita, Keisho Hirota, Yohei Ueda, Yugo Kanai, Yui Yamashita, Eri Kondo, Toshihito Fujii, Daisuke Taura, Masakatsu Sone, Akihiro Yasoda, Nobuya Inagak. Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans. Endocrine. vol 59. issue 2. 2018-10-24. PMID:29274063. |
growth hormone (gh) therapy in adults alters thyroid function, and acromegaly often involves thyroid disease. |
2018-10-24 |
2023-08-13 |
Not clear |
| Pinaki Dutta, Márta Korbonits, Naresh Sachdeva, Prakamya Gupta, Anand Srinivasan, Jagtar Singh Devgun, Ankur Bajaj, Kanchan Kumar Mukherje. Can immediate postoperative random growth hormone levels predict long-term cure in patients with acromegaly? Neurology India. vol 64. issue 2. 2018-10-11. PMID:26954802. |
growth hormone (gh) levels following oral glucose tolerance test (ogtt) at 12 weeks or later after surgery have been accepted as the most reliable parameter for defining remission and/or cure in patients with acromegaly. |
2018-10-11 |
2023-08-13 |
Not clear |
| Pinaki Dutta, Márta Korbonits, Naresh Sachdeva, Prakamya Gupta, Anand Srinivasan, Jagtar Singh Devgun, Ankur Bajaj, Kanchan Kumar Mukherje. Can immediate postoperative random growth hormone levels predict long-term cure in patients with acromegaly? Neurology India. vol 64. issue 2. 2018-10-11. PMID:26954802. |
this study was undertaken to evaluate the role of random gh levels in first 5 postoperative days as an early predictive tool for long-term remission of patients with acromegaly following transsphenoidal pituitary surgery (tss). |
2018-10-11 |
2023-08-13 |
Not clear |
| Ramesh R Dargad, Jai D Parekh, Rohit R Darga. Acromegaly with Dilated Cardiomyopathy. The Journal of the Association of Physicians of India. vol 64. issue 6. 2018-10-11. PMID:27739285. |
acromegaly is a rare condition with an approximate incidence of 3-4 new cases per million per year and occurs as a result of excess secretion of growth hormone (gh). |
2018-10-11 |
2023-08-13 |
Not clear |
| Onur Turan, Barış Akinci, Ahmet Omer Ikiz, Oya Itil, Ibrahim Oztura, Emel Ada, Bahri Akdeniz, Serkan Yener, Murat Kaya, Arzu Gedik, Abdurrahman Comlekc. Airway and sleep disorders in patients with acromegaly. The clinical respiratory journal. vol 12. issue 3. 2018-10-02. PMID:28224726. |
acromegaly is a multisystemic disorder caused by excessive secretion of growth hormone (gh). |
2018-10-02 |
2023-08-13 |
Not clear |
| Michiel J van Esdonk, Eline J M van Zutphen, Ferdinand Roelfsema, Alberto M Pereira, Piet H van der Graaf, Nienke R Biermasz, Jasper Stevens, Jacobus Burggraa. How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review. Pituitary. vol 21. issue 3. 2018-09-24. PMID:29605877. |
the aim of this review was to investigate the current methods that are being applied to measure and report growth hormone (gh) and insulin-like growth factor-1 (igf-1) as markers for drug effectiveness in clinical acromegaly research. |
2018-09-24 |
2023-08-13 |
Not clear |
| Fabienne Langlois, Randall Woltjer, Justin S Cetas, Maria Fleseri. Silent somatotroph pituitary adenomas: an update. Pituitary. vol 21. issue 2. 2018-09-04. PMID:29305680. |
diagnosis is invariably made post-operatively of a tumor immunopositive for gh (and pit-1 in selected cases) but without clinical acromegaly. |
2018-09-04 |
2023-08-13 |
Not clear |
| Fabienne Langlois, Randall Woltjer, Justin S Cetas, Maria Fleseri. Silent somatotroph pituitary adenomas: an update. Pituitary. vol 21. issue 2. 2018-09-04. PMID:29305680. |
beside normal igf-1 levels, a third of sghas displays elevated gh levels and some will eventually progress to acromegaly. |
2018-09-04 |
2023-08-13 |
Not clear |
| Jaime Guevara-Aguirre, Alexandra Guevara, Iván Palacios, Mónica Pérez, Patricio Prócel, Enrique Terá. GH and GHR signaling in human disease. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 38. 2018-08-30. PMID:29395968. |
in consequence, we selected acromegaly and laron syndrome due to gh receptor deficiency (ghrd) as models for excess and absence of gh action, and focused in the role of gh/ghr signaling in the genesis of cancer and diabetes. |
2018-08-30 |
2023-08-13 |
human |