| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kim Mja Claessen, Alberto M Pereira, Nienke R Biermas. Outcome of complications in acromegaly patients after long-term disease remission. Expert review of endocrinology & metabolism. vol 10. issue 5. 2019-11-20. PMID:30298766. |
acromegaly patients suffer from pathologically high growth hormone (gh) and igf-1 levels that in 99% of cases is due to a gh-producing pituitary adenoma. |
2019-11-20 |
2023-08-13 |
Not clear |
| Kevin Cj Yuen, Vera Popovi. Growth hormone replacement in patients with a history of malignancy: a review of the literature and best practice for offering treatment. Expert review of endocrinology & metabolism. vol 10. issue 3. 2019-11-20. PMID:30298774. |
evidence supporting this notion is derived from animal studies, epidemiological observations, patients with acromegaly and from therapeutic manipulation of gh and igf-i actions. |
2019-11-20 |
2023-08-13 |
Not clear |
| Verena Gounden, Yashna D Rampursat, Ishwarlal Jiala. Secretory tumors of the pituitary gland: a clinical biochemistry perspective. Clinical chemistry and laboratory medicine. vol 57. issue 2. 2019-10-28. PMID:30120907. |
acromegaly can be diagnosed by basal insulin growth-like factor 1 levels and the failure of growth hormone (gh) to suppress during an oral glucose tolerance test. |
2019-10-28 |
2023-08-13 |
Not clear |
| Eva Venegas-Moreno, Mari C Vazquez-Borrego, Elena Dios, Noelia Gros-Herguido, Alvaro Flores-Martinez, Esther Rivero-Cortés, Ainara Madrazo-Atutxa, Miguel A Japón, Raúl M Luque, Justo P Castaño, David A Cano, Alfonso Soto-Moren. Association between dopamine and somatostatin receptor expression and pharmacological response to somatostatin analogues in acromegaly. Journal of cellular and molecular medicine. vol 22. issue 3. 2019-10-21. PMID:29266696. |
acromegaly is a hormonal disorder resulting from excessive growth hormone (gh) secretion frequently produced by pituitary adenomas and consequent increase in insulin-like growth factor 1 (igf-i). |
2019-10-21 |
2023-08-13 |
human |
| João Paulo Almeida, Armando S Ruiz-Treviño, Buqing Liang, Sacit B Omay, Sathwik R Shetty, Yu-Ning Chen, Vijay K Anand, Kartikey Grover, Paul Christos, Theodore H Schwart. Reoperation for growth hormone-secreting pituitary adenomas: report on an endonasal endoscopic series with a systematic review and meta-analysis of the literature. Journal of neurosurgery. vol 129. issue 2. 2019-10-10. PMID:28862548. |
cases involving patients with acromegaly secondary to growth hormone (gh)-secreting adenomas who underwent eea were selected for chart review and divided into 2 groups: first-time surgery and reoperation. |
2019-10-10 |
2023-08-13 |
Not clear |
| Edward H Oldfield, John A Jane, Michael O Thorner, Carrie L Pledger, Jason P Sheehan, Mary Lee Vanc. Correlation between GH and IGF-1 during treatment for acromegaly. Journal of neurosurgery. vol 126. issue 6. 2019-08-26. PMID:27858572. |
correlation between gh and igf-1 during treatment for acromegaly. |
2019-08-26 |
2023-08-13 |
Not clear |
| Edward H Oldfield, John A Jane, Michael O Thorner, Carrie L Pledger, Jason P Sheehan, Mary Lee Vanc. Correlation between GH and IGF-1 during treatment for acromegaly. Journal of neurosurgery. vol 126. issue 6. 2019-08-26. PMID:27858572. |
objective the relationship between growth hormone (gh) and insulin-like growth factor-1 (igf-1) in patients with acromegaly as serial levels drop over time after treatment has not been examined previously. |
2019-08-26 |
2023-08-13 |
Not clear |
| Edward H Oldfield, John A Jane, Michael O Thorner, Carrie L Pledger, Jason P Sheehan, Mary Lee Vanc. Correlation between GH and IGF-1 during treatment for acromegaly. Journal of neurosurgery. vol 126. issue 6. 2019-08-26. PMID:27858572. |
to examine the correlation between gh and igf-1 and igf-1 z-scores over a wide range of gh levels, the authors examined serial gh and igf-1 levels at intervals before and after surgery and radiosurgery for acromegaly. |
2019-08-26 |
2023-08-13 |
Not clear |
| Edward H Oldfield, John A Jane, Michael O Thorner, Carrie L Pledger, Jason P Sheehan, Mary Lee Vanc. Correlation between GH and IGF-1 during treatment for acromegaly. Journal of neurosurgery. vol 126. issue 6. 2019-08-26. PMID:27858572. |
methods this retrospective analysis correlates 414 pairs of gh and igf-1 values in 93 patients with acromegaly. |
2019-08-26 |
2023-08-13 |
Not clear |
| Edward H Oldfield, John A Jane, Michael O Thorner, Carrie L Pledger, Jason P Sheehan, Mary Lee Vanc. Correlation between GH and IGF-1 during treatment for acromegaly. Journal of neurosurgery. vol 126. issue 6. 2019-08-26. PMID:27858572. |
conclusions in acromegaly, although igf-1 levels represent a combination of the integrated effects of gh secretion and gh action, the tumor produces gh, not igf-1. |
2019-08-26 |
2023-08-13 |
Not clear |
| Aleksandra Jawiarczyk-Przybyłowska, Beata Wojtczak, James Whitworth, Krzysztof Sutkowski, Martin Bidlingmaier, Márta Korbonits, Marek Bolanowsk. Acromegaly associated with GIST, non-small cell lung carcinoma, clear cell renal carcinoma, multiple myeloma, medulla oblongata tumour, adrenal adenoma, and follicular thyroid nodules. Endokrynologia Polska. vol 70. issue 2. 2019-08-26. PMID:30742299. |
acromegaly is associated with increased growth hormone (gh) and insulin-like growth factor-i (igf-i) secretion which may support tumour development and growth. |
2019-08-26 |
2023-08-13 |
Not clear |
| Oguz Hancerliogullari, Rahman Senocak, Sahin Kaymak, Emin Lapsekili, Huseyin Sina. An uncommon cause of acute abdomen in an acromegalic patient: colonic volvulus. Annali italiani di chirurgia. vol 89. 2019-08-21. PMID:30665214. |
acromegaly is a chronic endocrine disease, typically caused by a pituitary adenoma leading to increased circulating gh levels and increased igf-i secretion by peripheral tissues. |
2019-08-21 |
2023-08-13 |
Not clear |
| Oguz Hancerliogullari, Rahman Senocak, Sahin Kaymak, Emin Lapsekili, Huseyin Sina. An uncommon cause of acute abdomen in an acromegalic patient: colonic volvulus. Annali italiani di chirurgia. vol 89. 2019-08-21. PMID:30665214. |
gh and igf-1 have an irreversible effect on colonic collagen synthesis in acromegaly and has been proposed to be correlated with the presence of dolichocolon. |
2019-08-21 |
2023-08-13 |
Not clear |
| Cesar Luiz Boguszewski, Margaret Cristina da Silva Boguszewsk. Growth Hormone's Links to Cancer. Endocrine reviews. vol 40. issue 2. 2019-08-14. PMID:30500870. |
in contrast, the link between gh excess and cancer risk in acromegaly patients is much less clear, and cancer screening in acromegaly has been a highly controversial issue. |
2019-08-14 |
2023-08-13 |
Not clear |
| Cesar Luiz Boguszewski, Margaret Cristina da Silva Boguszewsk. Growth Hormone's Links to Cancer. Endocrine reviews. vol 40. issue 2. 2019-08-14. PMID:30500870. |
recent studies have shown that increased life expectancy in acromegaly patients who attain normal gh and igf-i levels is associated with more deaths due to age-related cancers. |
2019-08-14 |
2023-08-13 |
Not clear |
| Burak Kocak, Emine Sebnem Durmaz, Pinar Kadioglu, Ozge Polat Korkmaz, Nil Comunoglu, Necmettin Tanriover, Naci Kocer, Civan Islak, Osman Kizilkili. Predicting response to somatostatin analogues in acromegaly: machine learning-based high-dimensional quantitative texture analysis on T2-weighted MRI. European radiology. vol 29. issue 6. 2019-08-05. PMID:30506213. |
to investigate the value of machine learning (ml)-based high-dimensional quantitative texture analysis (qta) on t2-weighted magnetic resonance imaging (mri) in predicting response to somatostatin analogues (sa) in acromegaly patients with growth hormone (gh)-secreting pituitary macroadenoma, and to compare the qta with quantitative and qualitative t2-weighted relative signal intensity (rsi) and immunohistochemical evaluation. |
2019-08-05 |
2023-08-13 |
Not clear |
| Lisa Sze, Oliver Tschopp, Marian C Neidert, René L Bernays, Claudia Ghirlanda, Cornelia Zwimpfer, Peter Wiesli, Christoph Schmi. Soluble delta-like 1 homolog decreases in patients with acromegaly following pituitary surgery: A potential mediator of adipogenesis suppression by growth hormone? Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 45. 2019-08-02. PMID:30818110. |
gh excess in acromegaly leads to lower fat mass and insulin resistance; both reverse following pituitary surgery. |
2019-08-02 |
2023-08-13 |
Not clear |
| Annamaria Colao, Ludovica F S Grasso, Carolina Di Somma, Rosario Pivonell. Acromegaly and Heart Failure. Heart failure clinics. vol 15. issue 3. 2019-07-29. PMID:31079698. |
in patients with acromegaly, chronic gh and igf-i excess commonly causes a specific cardiomyopathy characterized by a concentric cardiac hypertrophy associated with diastolic dysfunction and, in later stages, with systolic dysfunction ending in heart failure in untreated and uncontrolled patients. |
2019-07-29 |
2023-08-13 |
Not clear |
| Anil K Pasupulati, Ram K Meno. Growth hormone and chronic kidney disease. Current opinion in nephrology and hypertension. vol 28. issue 1. 2019-07-15. PMID:30394899. |
elevated circulating levels of growth hormone (gh) and/or increased expression of the gh receptor in the kidney are associated with the development of nephropathy in type1 diabetes and acromegaly. |
2019-07-15 |
2023-08-13 |
Not clear |
| Michał Elbaum, Łukasz Mizera, Marek Bolanowsk. The real costs of acromegaly: analysis of different therapies. Endokrynologia Polska. vol 70. issue 1. 2019-07-12. PMID:30843180. |
acromegaly is a rare, chronic condition caused by growth hormone (gh) overproduction, usually due to a benign tumour of the pituitary gland. |
2019-07-12 |
2023-08-13 |
Not clear |