Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Yukihide Koyama, Tomio Andoh, Yoshinori Kamiya, Tomoyuki Miyazaki, Koichi Maruyama, Takayuki Kariya, Takahisa Got. Bumetanide, an Inhibitor of NKCC1 (Na-K-2Cl Cotransporter Isoform 1), Enhances Propofol-Induced Loss of Righting Reflex but Not Its Immobilizing Actions in Neonatal Rats. PloS one. vol 11. issue 10. 2017-06-14. PMID:27783647. |
gamma-aminobutyric acid (gaba) has been shown to induce excitation on immature neurons due to increased expression of na+-k+-2cl- co-transporter isoform 1 (nkcc1), and the transition of gabaergic signaling from excitatory to inhibitory occurs before birth in the rat spinal cord and spreads rostrally according to the developmental changes in cation-chloride co-transporter expression. |
2017-06-14 |
2023-08-13 |
rat |
Yung-Jen Huang, Kuan H Lee, Lauren Murphy, Sandra M Garraway, James W Gra. Acute spinal cord injury (SCI) transforms how GABA affects nociceptive sensitization. Experimental neurology. vol 285. issue Pt A. 2017-05-08. PMID:27639636. |
acute spinal cord injury (sci) transforms how gaba affects nociceptive sensitization. |
2017-05-08 |
2023-08-13 |
rat |
Yung-Jen Huang, Kuan H Lee, Lauren Murphy, Sandra M Garraway, James W Gra. Acute spinal cord injury (SCI) transforms how GABA affects nociceptive sensitization. Experimental neurology. vol 285. issue Pt A. 2017-05-08. PMID:27639636. |
the current study provides evidence that spinal cord injury (sci) transforms how gaba affects nociceptive transmission within the spinal cord, recapitulating an earlier developmental state wherein gaba has an excitatory effect. |
2017-05-08 |
2023-08-13 |
rat |
Katherine A Mifflin, Curtis Benson, Kevin C Thorburn, Glen B Baker, Bradley J Ker. Manipulation of Neurotransmitter Levels Has Differential Effects on Formalin-Evoked Nociceptive Behavior in Male and Female Mice. The journal of pain. vol 17. issue 4. 2016-12-27. PMID:26748043. |
changes in serotonin (5-hydroxytryptamine; 5-ht), noradrenaline (na), and γ-aminobutyric acid (gaba) levels in the spinal cord are known to occur in response to nociceptive stimuli, yet little research has examined possible underlying sex differences in these changes and how they might affect nociception. |
2016-12-27 |
2023-08-13 |
mouse |
Carlos Gonzalez-Islas, Miguel Angel Garcia-Bereguiain, Brendan O'Flaherty, Peter Wenne. Tonic nicotinic transmission enhances spinal GABAergic presynaptic release and the frequency of spontaneous network activity. Developmental neurobiology. vol 76. issue 3. 2016-10-21. PMID:26061781. |
rather, we found that nachr activation tonically enhanced evoked and spontaneous presynaptic release of gaba in the embryonic spinal cord. |
2016-10-21 |
2023-08-13 |
Not clear |
Siroosi Shokoofeh, Manaheji Homa, Dargahi Leila, Daniali Samir. Expression of spinal cord GABA transporter 1 in morphine-tolerant male Wistar rats. European journal of pharmacology. vol 767. 2016-10-05. PMID:26463038. |
expression of spinal cord gaba transporter 1 in morphine-tolerant male wistar rats. |
2016-10-05 |
2023-08-13 |
rat |
C-K S. Modulation of synchronous sympathetic firing behaviors by endogenous GABA(A) and glycine receptor-mediated activities in the neonatal rat spinal cord in vitro. Neuroscience. vol 312. 2016-09-29. PMID:26598070. |
modulation of synchronous sympathetic firing behaviors by endogenous gaba(a) and glycine receptor-mediated activities in the neonatal rat spinal cord in vitro. |
2016-09-29 |
2023-08-13 |
rat |
Belinda R Bowman, Ann K Goodchil. GABA and enkephalin tonically alter sympathetic outflows in the rat spinal cord. Autonomic neuroscience : basic & clinical. vol 193. 2016-08-28. PMID:26329875. |
gaba and enkephalin tonically alter sympathetic outflows in the rat spinal cord. |
2016-08-28 |
2023-08-13 |
rat |
Belinda R Bowman, Ann K Goodchil. GABA and enkephalin tonically alter sympathetic outflows in the rat spinal cord. Autonomic neuroscience : basic & clinical. vol 193. 2016-08-28. PMID:26329875. |
thus gaba acting in the spinal cord plays an important role in the tonic suppression of sympathetic outflows while enkephalin appears to play only a minor role. |
2016-08-28 |
2023-08-13 |
rat |
Talita Hélen Ferreira-Vieira, Danielle Marra de Freitas-Silva, Andrea Frozino Ribeiro, Sílvia Rejane Castanheira Pereira, Ângela Maria Ribeir. Perinatal thiamine restriction affects central GABA and glutamate concentrations and motor behavior of adult rat offspring. Neuroscience letters. vol 617. 2016-08-08. PMID:26836141. |
after behavioral tests, their thalamus, cerebellum and spinal cord were dissected for glutamate and gaba quantifications by high performance liquid chromatography. |
2016-08-08 |
2023-08-13 |
rat |
Lingxiao Deng, Yiwen Ruan, Chen Chen, Christian Corbin Frye, Wenhui Xiong, Xiaoming Jin, Kathryn Jones, Dale Sengelaub, Xiao-Ming X. Characterization of dendritic morphology and neurotransmitter phenotype of thoracic descending propriospinal neurons after complete spinal cord transection and GDNF treatment. Experimental neurology. vol 277. 2016-06-27. PMID:26730519. |
for the group receiving fg injections, immunohistochemistry for glutamate, choline acetyltransferase (chat), glycine, and gaba was performed in the t7-9 spinal cord. |
2016-06-27 |
2023-08-13 |
rat |
Antonino Cannas, Paolo Solla, Marcello Mascia, Antonella Muroni, Gian Luca Floris, Giuseppe Borghero, Gianni Orofino, Mario Meloni, Francesco Marros. Pisa-Like Syndrome Under Baclofen in a Patient With Spastic Hemiparesis due to Ischemic Stroke. Clinical neuropharmacology. vol 38. issue 5. 2016-06-13. PMID:26366969. |
baclofen reduces the spasticity depressing the monosinaptic and polisinaptic reflex in the spinal cord by stimulating gamma-aminobutyric acid b (gaba-b) receptors, which inhibit the release of excitatory amino acids, glutamate and aspartate. |
2016-06-13 |
2023-08-13 |
Not clear |
Rafael Lazo-Gómez, Ricardo Tapi. Motor Alterations Induced by Chronic 4-Aminopyridine Infusion in the Spinal Cord In vivo: Role of Glutamate and GABA Receptors. Frontiers in neuroscience. vol 10. 2016-05-31. PMID:27242406. |
motor alterations induced by chronic 4-aminopyridine infusion in the spinal cord in vivo: role of glutamate and gaba receptors. |
2016-05-31 |
2023-08-13 |
rat |
Elham Jalalvand, Brita Robertson, Peter Wallén, Sten Grillne. Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3. Nature communications. vol 7. 2016-05-17. PMID:26743691. |
we recently identified one type of laterally projecting csf-c cell in lamprey spinal cord with neuronal properties that expresses gaba and somatostatin. |
2016-05-17 |
2023-08-13 |
Not clear |
Mohsin Ijaz, Hassan Tariq, Muhammad Kashif, Jose Gomez Marque. Encephalopathy and hypotonia due to baclofen toxicity in a patient with end-stage renal disease. The American journal of case reports. vol 16. 2016-01-07. PMID:25895118. |
baclofen is a centrally acting gamma-aminobutyric acid agonist used for the symptomatic relief of skeletal muscle spasm and spasticity in traumatic spinal cord lesions, multiple sclerosis, cerebral palsy, and stroke. |
2016-01-07 |
2023-08-13 |
Not clear |
Marco Milanese, Tiziana Bonifacino, Ernesto Fedele, Claudia Rebosio, Luca Cattaneo, Fabio Benfenati, Cesare Usai, Giambattista Bonann. Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: a mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis. Neurobiology of disease. vol 74. 2016-01-06. PMID:25497732. |
exocytosis regulates trafficking of gaba and glycine heterotransporters in spinal cord glutamatergic synapses: a mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis. |
2016-01-06 |
2023-08-13 |
mouse |
Marco Milanese, Tiziana Bonifacino, Ernesto Fedele, Claudia Rebosio, Luca Cattaneo, Fabio Benfenati, Cesare Usai, Giambattista Bonann. Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: a mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis. Neurobiology of disease. vol 74. 2016-01-06. PMID:25497732. |
the impact of synaptic vesicle endo-exocytosis on the trafficking of nerve terminal heterotransporters was studied by monitoring membrane expression and function of the gaba transporter-1 (gat-1) and of type-1/2 glycine (gly) transporters (glyt-1/2) at spinal cord glutamatergic synaptic boutons. |
2016-01-06 |
2023-08-13 |
mouse |
Marco Milanese, Tiziana Bonifacino, Ernesto Fedele, Claudia Rebosio, Luca Cattaneo, Fabio Benfenati, Cesare Usai, Giambattista Bonann. Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: a mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis. Neurobiology of disease. vol 74. 2016-01-06. PMID:25497732. |
impaired endocytosis in amph-i ko mice increased gat-1 membrane expression and [(3)h]gaba uptake in spinal cord synaptosomes. |
2016-01-06 |
2023-08-13 |
mouse |
Amanda Jonsson, Zhiyang Song, David Nilsson, Björn A Meyerson, Daniel T Simon, Bengt Linderoth, Magnus Berggre. Therapy using implanted organic bioelectronics. Science advances. vol 1. issue 4. 2015-11-25. PMID:26601181. |
devices were implanted onto the spinal cord of rats, and 2 days after implantation, local delivery of the inhibitory neurotransmitter γ-aminobutyric acid (gaba) was initiated. |
2015-11-25 |
2023-08-13 |
rat |
Hai Lin, Bong Ha Heo, Woong Mo Kim, Yong Chul Kim, Myung Ha Yoo. Antiallodynic effect of tianeptine via modulation of the 5-HT7 receptor of GABAergic interneurons in the spinal cord of neuropathic rats. Neuroscience letters. vol 598. 2015-09-14. PMID:25982324. |
both gad65 expression and the gaba concentration in the spinal cord were decreased in neuropathic rats but were increased by tianeptine. |
2015-09-14 |
2023-08-13 |
rat |