| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I H Pang, M R Vask. Morphine and norepinephrine but not 5-hydroxytryptamine and gamma-aminobutyric acid inhibit the potassium-stimulated release of substance P from rat spinal cord slices. Brain research. vol 376. issue 2. 1986-09-16. PMID:2425894. |
we studied whether morphine, norepinephrine (ne), 5-hydroxytryptamine (5-ht) and gamma-aminobutyric acid (gaba) inhibit the potassium-stimulated release of substance p (sp) from rat spinal cord slices. |
1986-09-16 |
2023-08-11 |
rat |
| M J McLean, R L Macdonal. Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture. The Journal of pharmacology and experimental therapeutics. vol 237. issue 3. 1986-07-16. PMID:3086538. |
at concentrations of 120 to 1000 microm, including the upper limit of therapeutic range, navp did not affect postsynaptic gaba responses in 80% of spinal cord neurons. |
1986-07-16 |
2023-08-11 |
mouse |
| G A Robinson, M E Goldberge. The development and recovery of motor function in spinal cats. II. Pharmacological enhancement of recovery. Experimental brain research. vol 62. issue 2. 1986-06-27. PMID:3709721. |
the effects of the gamma-aminobutyric acid (gaba) antagonist bicuculline (bcc) on hindlimb motor performance was examined in mature spinal cats with spinal cord transections made either on the day of birth or at approximately two weeks postpartum and in chronic adult cats with spinal transections made in adulthood. |
1986-06-27 |
2023-08-11 |
Not clear |
| M D Majewska, N L Harrison, R D Schwartz, J L Barker, S M Pau. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science (New York, N.Y.). vol 232. issue 4753. 1986-06-11. PMID:2422758. |
at concentrations between 10(-7) and 10(-5)m both steroids inhibited binding of the convulsant t-butylbicyclophosphorothionate to the gaba-receptor complex and increased the binding of the benzodiazepine flunitrazepam; they also stimulated chloride uptake (as measured by uptake of 36cl-) into isolated brain vesicles, and potentiated the inhibitory actions of gaba in cultured rat hippocampal and spinal cord neurons. |
1986-06-11 |
2023-08-11 |
rat |
| Ts V Serbeniuk, T V Lelekov. [Effect of gamma-aminobutyric acid on neurons of the spinal lymphatic center]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 71. issue 11. 1986-02-28. PMID:3002870. |
in the frog isolated perfused 7-11th spinal cord segments with the lymphatic center, gaba inhibited both the activity of pace-maker neurons and the burst-type activity of lymphatic motoneurons. |
1986-02-28 |
2023-08-11 |
Not clear |
| E Hösli, P Krogsgaard-Larsen, L Hösl. Autoradiographic localization of binding sites for the gamma-aminobutyric acid analogues 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (THIP)isoguvacine and baclofen on cultured neurons of rat cerebellum and spinal cord. Neuroscience letters. vol 61. issue 1-2. 1986-02-18. PMID:3001590. |
autoradiographic localization of binding sites for the gamma-aminobutyric acid analogues 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol (thip)isoguvacine and baclofen on cultured neurons of rat cerebellum and spinal cord. |
1986-02-18 |
2023-08-11 |
rat |
| D A Mather. Spontaneous and GABA-induced single channel currents in cultured murine spinal cord neurons. Canadian journal of physiology and pharmacology. vol 63. issue 10. 1986-02-17. PMID:2416415. |
application of the putative inhibitory transmitter gamma-aminobutyric acid (0.5-10 microm) to outside-out patches of spinal cord cell membrane induced single channel currents in 10 out of 15 patches tested. |
1986-02-17 |
2023-08-11 |
mouse |
| C M Rovaine. Effects of groups of propriospinal interneurons on fictive swimming in the isolated spinal cord of the lamprey. Journal of neurophysiology. vol 54. issue 4. 1986-01-09. PMID:2999351. |
when a middle region of spinal cord was inhibited in a compartment with gaba or glycine, the caudal spinal cord could entrain the bursts in rostral ventral roots. |
1986-01-09 |
2023-08-11 |
Not clear |
| M Massott. Electroencephalographic investigations in rabbits of drugs acting at GABA-benzodiazepine-barbiturate/picrotoxin receptors complex. Pharmacology, biochemistry, and behavior. vol 23. issue 4. 1986-01-07. PMID:2999834. |
drugs which reduce gaba synaptic activity (bicuculline, inverse bdz agonists, ptz, picrotoxin and ro 5-3663) induce three dose-dependent stages of eeg changes: trains of slow waves, trains of spike-and-wave complexes and paroxysmal activity in the rostral encephalic structures without apparent changes of the electrical activity in the spinal cord. |
1986-01-07 |
2023-08-11 |
Not clear |
| J E Lamborghini, A Ile. Development of a high-affinity GABA uptake system in embryonic amphibian spinal neurons. Developmental biology. vol 112. issue 1. 1985-12-16. PMID:3932109. |
we have found interneurons in the xenopus embryo spinal cord which accumulate gaba by a high-affinity uptake system. |
1985-12-16 |
2023-08-11 |
xenopus_laevis |
| J W Commission. The synthesis and metabolism of catecholamines in the spinal cord of the rat after acute and chronic transections. Brain research. vol 347. issue 1. 1985-12-13. PMID:2864984. |
as judged from the levels of gamma-aminobutyric acid (gaba) and glutamic acid (glutamate) present in the transected cord, no major metabolic derangement of the spinal cord tissue seemed to have been present at the times the experiments were done. |
1985-12-13 |
2023-08-11 |
rat |
| N Saadé, S J Jabbur, P D Wal. Effects of 4-aminopyridine, GABA and bicuculline on cutaneous receptive fields of cat dorsal horn neurons. Brain research. vol 344. issue 2. 1985-11-20. PMID:2994840. |
4-aminopyridine (4-ap), bicuculline and gaba were applied locally to dorsal horn cells in the lumbar spinal cord in nembutal-anaesthetized cats and in spinal cats. |
1985-11-20 |
2023-08-11 |
cat |
| I V Komissarov, I I Abramet. [Ionic mechanisms of the effects of phenibut and GABA unrelated to changes in the function of chloride channels]. Neirofiziologiia = Neurophysiology. vol 17. issue 4. 1985-11-06. PMID:2995847. |
it is established that beta-phenyl-gaba (phenibut) and partly gaba elicit direct depolarization of the isolated spinal cord motoneurons. |
1985-11-06 |
2023-08-11 |
Not clear |
| C Y Chan, D H Far. Modulation of neurotransmitter action: control of the gamma-aminobutyric acid response through the benzodiazepine receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 9. 1985-10-17. PMID:2863335. |
the ability of several homologous benzodiazepine and heterologous nonbenzodiazepine ligands to alter the conductance increase induced in spinal cord neurons by gamma-aminobutyric acid (gaba) was determined. |
1985-10-17 |
2023-08-11 |
Not clear |
| S H Zorn, S J Enn. The effect of mouse spinal cord transection on the antinociceptive response to the gamma-aminobutyric acid agonists THIP (4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridine-3-ol) and baclofen. Brain research. vol 338. issue 2. 1985-10-01. PMID:3861208. |
the effect of mouse spinal cord transection on the antinociceptive response to the gamma-aminobutyric acid agonists thip (4,5,6,7-tetrahydroisoxazolo [5,4-c]pyridine-3-ol) and baclofen. |
1985-10-01 |
2023-08-11 |
mouse |
| J H Wible, R L Zerbe, J A DiMicc. Stimulation of vasopressin release by gamma-aminobutyric acid antagonists in spinal cord transected rats. The Journal of pharmacology and experimental therapeutics. vol 234. issue 2. 1985-09-17. PMID:2991498. |
stimulation of vasopressin release by gamma-aminobutyric acid antagonists in spinal cord transected rats. |
1985-09-17 |
2023-08-11 |
rat |
| K Hirayama, M Inouye, T Fujisak. Alteration of putative amino acid levels and morphological findings in neural tissues of methylmercury-intoxicated mice. Archives of toxicology. vol 57. issue 1. 1985-08-16. PMID:2861802. |
the contents of taurine, aspartate, glutamate, glycine, and gamma-aminobutyric acid were determined in tissue and crude synaptosomal (p2) fraction of cerebellum, cerebral cortex, and spinal cord of methylmercury-treated mice with or without ataxia. |
1985-08-16 |
2023-08-11 |
mouse |
| D R Curtis, R Mali. Glycine antagonism by RU 5135. European journal of pharmacology. vol 110. issue 3. 1985-08-14. PMID:4007055. |
in the spinal cord of the pentobarbitone-anaesthetised cat, microelectrophoretic ru 5135, a steroid derivative, was a potent strychnine-like glycine antagonist, having less effect on the inhibition by gaba of neuronal firing. |
1985-08-14 |
2023-08-11 |
cat |
| J R Keeler, C J Helk. Spinal cord substance P mediates bicuculline-induced activation of cardiovascular responses from the ventral medulla. Journal of the autonomic nervous system. vol 13. issue 1. 1985-07-25. PMID:2582025. |
since gamma-aminobutyric acid (gaba) in the ventral medulla inhibits, and gaba-receptor antagonists excite sympathetic outflow to the cardiovascular system, experiments were done to determine if sp and serotonin in the spinal cord were responsible for mediating these gabaergic effects. |
1985-07-25 |
2023-08-11 |
rat |
| J R Keeler, C J Helk. Spinal cord substance P mediates bicuculline-induced activation of cardiovascular responses from the ventral medulla. Journal of the autonomic nervous system. vol 13. issue 1. 1985-07-25. PMID:2582025. |
intrathecal injection of 5,7-dihydroxytryptamine two weeks prior to the experiments resulted in 56% depletion of serotonin in the thoracic spinal cord, but did not change either basal map and hr, nor the responses to bicuculline and gaba applied to the ventral surface of the medulla. |
1985-07-25 |
2023-08-11 |
rat |