| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Benneth Ben-Azu, Olusegun G Adebayo, Emuesiri G Moke, Adrian I Omogbiya, Benjamin Oritsemuelebi, Emmanuel O Chidebe, Emuesiri Umukoro, Eze K Nwangwa, Emmanuel Etijoro, Emmanuel Umukoro, Elizabeth J Mamudu, Chineye Chukwum. Geraniol attenuates behavioral and neurochemical impairments by inhibitions of HPA-axis and oxido-inflammatory perturbations in mice exposed to post-traumatic stress disorder. Journal of psychiatric research. vol 168. 2023-11-01. PMID:37913743. |
geraniol also increased glutathione, superoxide-dismutase, and catalase levels as well as dopamine, serotonin concentrations and gabaergic glutamic acid decarboxylase enzyme activity in the striatum, prefrontal cortex and hippocampus in the ptsd-mice relative to sps control. |
2023-11-01 |
2023-11-08 |
mouse |
| Hyomin Ahn, Kichul Park, Dongyoung Kim, Sung-Gil Chi, Kee-Hyun Choi, Seo-Jung Han, Chiman Son. Implications for Combination Therapy of Selective Monoamine Reuptake Inhibitors on Dopamine Transporters. Biomedicines. vol 11. issue 10. 2023-10-30. PMID:37893219. |
monoamine transporters, including dopamine, norepinephrine, and serotonin transporters (dat, net, and sert, respectively), are important therapeutic targets due to their essential roles in the brain. |
2023-10-30 |
2023-11-08 |
Not clear |
| Elham Pirayesh, Hoa Quynh Do, Garren Ferreira, Akash Pandhare, Zackary Ryan Gallardo, Michaela Janse. Identification of a binding site for bupropion in bioRxiv : the preprint server for biology. 2023-10-24. PMID:37873398. |
bupropion inhibits dopamine and norepinephrine reuptake transporters and eukaryotic cation-conducting pentameric ligand-gated ion channels (plgics), such as nicotinic acetylcholine (nach) and serotonin type 3a (5-ht3a) receptors, at clinically relevant concentrations. |
2023-10-24 |
2023-11-08 |
Not clear |
| Kaito Kurogi, Fuka Taniguchi, Ryohei Matsuo, Marina Shinozuka, Raiki Suzaki, Shinobu Yasu. Increased depression-like behaviors with altered brain dopamine metabolisms in male mice housed in large cages are alleviated by bupropion. European journal of pharmacology. 2023-10-20. PMID:37858834. |
in mice housed in large cages, sex-specific dysregulation of brain monoamine systems was observed; dopamine turnover to homovanillic acid or norepinephrine in the prefrontal cortex was elevated in males, while serotonin turnover to 5-hydroxyindoleacetic acid in the amygdala was increased in females. |
2023-10-20 |
2023-11-08 |
mouse |
| Hongyan Pei, Rui Du, Zhongmei He, Jinhao Bi, Liping Zhai, Heping She. Atractylenolide I improves behaviors in mice with depression-like phenotype by modulating neurotransmitter balance via 5-HT2A. Phytotherapy research : PTR. 2023-10-19. PMID:37857401. |
through elevated plus maze, open field, tail suspension, and forced swimming tests, the behavioral changes of mice with depression (chronic unpredictable mild stress [cums]) were examined, and the levels of neurotransmitters including serotonin, dopamine, and norepinephrine (5-ht, da, and ne) were determined. |
2023-10-19 |
2023-11-08 |
mouse |
| Georgia E Hodes, Debra Bangasser, Ioannis Sotiropoulos, Nikolaos Kokras, Christina Dall. Sex Differences in Stress Response: Classical Mechanisms and Beyond. Current neuropharmacology. 2023-10-19. PMID:37855285. |
then, we present sex differences in neurotransmitter levels, such as serotonin, dopamine, glutamate and gaba, as well as indices of neurodegeneration, such as amyloid β and tau. |
2023-10-19 |
2023-11-08 |
Not clear |
| Inès Khsime, Marie Boulain, Abderrahman Fettah, Abdeslam Chagraoui, Gilles Courtand, Philippe De Deurwaerdère, Laurent Juvin, Grégory Barrièr. Limiting Monoamines Degradation Increases L-DOPA Pro-Locomotor Action in Newborn Rats. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834195. |
tissue measurements of monoamines (dopamine, noradrenaline, serotonin and some of their metabolites) in the cervical and lumbar spinal cord confirmed the regional efficacy of each inhibitor toward their respective enzyme. |
2023-10-14 |
2023-10-15 |
rat |
| Shubham Ghuge, Ziaur Rahman, Nagesh Bhale, Amol G Dikundwar, Manoj P Dandeka. Multistrain probiotic rescinds quinpirole-induced obsessive-compulsive disorder phenotypes by reshaping of microbiota gut-brain axis in rats. Pharmacology, biochemistry, and behavior. 2023-10-07. PMID:37804865. |
our probiotic formulation also prevented the elevated mrna expression of interleukin-6, tumor-necrosis factor-α, and c-reactive protein in the amygdala and dysregulated levels of 5-hydroxytryptamine, dopamine, and noradrenaline in the frontal cortex of quinpirole-injected rats. |
2023-10-07 |
2023-10-15 |
rat |
| Satomi Kobayashi, Mie Kajiwara, Yilong Cui, Takeo Sako, Tetsuya Sasabe, Emi Hayashinaka, Yasuhiro Wada, Masayuki Kobayash. Activation of multiple neuromodulatory systems in alert rats acquiring conditioned taste aversion revealed by positron emission tomography. Brain research. 2023-10-07. PMID:37805008. |
conditioned taste aversion (cta) is an essential ability for animals to consume food safely and is regulated by neuromodulatory systems including the dopamine, noradrenaline, serotonin, and acetylcholine systems. |
2023-10-07 |
2023-10-15 |
rat |
| Vassilina Tsopela, Evangelos Korakidis, Despoina Lagou, Katerina I Kalliampakou, Raphaela S Milona, Eirini Kyriakopoulou, George Mpekoulis, Ioanna Gemenetzi, Elli-Anna Stylianaki, Constantinos D Sideris, Aggelina Sioli, Dionysis Kefallinos, Diamantis C Sideris, Vassilis Aidinis, Aristides G Eliopoulos, Konstantinos Kambas, Dido Vassilacopoulou, Niki Vassilak. L-Dopa decarboxylase modulates autophagy in hepatocytes and is implicated in dengue virus-caused inhibition of autophagy completion. Biochimica et biophysica acta. Molecular cell research. 2023-10-01. PMID:37778471. |
the enzyme l-dopa decarboxylase (ddc) synthesizes the catecholamine dopamine and the indolamine serotonin. |
2023-10-01 |
2023-10-07 |
human |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
agonists of dopamine d2 receptors (d2r), 5-hydroxytryptamine (5-ht, serotonin) receptors (5-htr) and ghrelin receptors (ghsr) activate neurons in the lumbosacral defecation centre, and act as 'colokinetics', leading to increased propulsive colonic motility, in vivo. |
2023-09-29 |
2023-10-07 |
mouse |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
whole cell electrophysiology in adult mice spinal cord revealed that dopamine, serotonin, α-methylserotonin and capromorelin each caused inward, excitatory currents in overlapping populations of lumbosacral pgns. |
2023-09-29 |
2023-10-07 |
mouse |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
key points: dopamine, 5-hydroxytryptamine (5-ht, serotonin) and ghrelin (ghsr) receptor agonists increase colorectal motility and have been postulated to act at receptors on parasympathetic preganglionic neurons (pgns) in the lumbosacral spinal cord. |
2023-09-29 |
2023-10-07 |
mouse |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
we aimed to determine which neurons in the lumbosacral spinal cord express dopamine, serotonin and ghsr receptors, their neural inputs, and whether agonists at these receptors excite them. |
2023-09-29 |
2023-10-07 |
mouse |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
we show that dopamine, serotonin and ghrelin receptor transcripts are contained in the same pgns and that these neurons have closely associated tyrosine hydroxylase and serotonin boutons. |
2023-09-29 |
2023-10-07 |
mouse |
| Mitchell T Ringuet, Ada Koo, Sebastian G B Furness, Stuart J McDougall, John B Furnes. Sites and mechanisms of action of colokinetics at dopamine, ghrelin and serotonin receptors in the rodent lumbosacral defecation centre. The Journal of physiology. 2023-09-29. PMID:37772438. |
whole cell electrophysiology revealed that dopamine, serotonin and ghsr receptor agonists induce an inward excitatory current in overlapping populations of lumbosacral pgns. |
2023-09-29 |
2023-10-07 |
mouse |
| Zeljka Korade, Allison Anderson, Marta Balog, Keri A Tallman, Ned A Porter, Karoly Mirnic. Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis. Biomolecules. vol 13. issue 9. 2023-09-28. PMID:37759721. |
in addition to their effects on dopamine and serotonin systems, both of these compounds are inhibitors of the 7-dehydrocholesterol reductase (dhcr7) enzyme. |
2023-09-28 |
2023-10-07 |
mouse |
| Heba-Tallah Abd Elrahim Abd Elkader, Ahmed S Al-Sham. Chronic exposure to bisphenol A induces behavioural, neurochemical, histological, and ultrastructural alterations in the ganglia tissue of the date mussels Lithophaga lithophaga. Environmental science and pollution research international. 2023-09-28. PMID:37768489. |
bpa causes neurotoxicity, as evidenced by concentration-dependent inhibition of acetylcholinesterase, dopamine, and serotonin. |
2023-09-28 |
2023-10-07 |
human |
| Amira M El-Moslemany, Mai Hussein Abd-Elfatah, Nawal A Tahoon, Rasha M Bahnasy, Badriyah S Alotaibi, Heba I Ghamry, Mustafa Shukr. Mechanistic Assessment of Anise Seeds and Clove Buds against the Neurotoxicity Caused by Metronidazole in Rats: Possible Role of Antioxidants, Neurotransmitters, and Cytokines. Toxics. vol 11. issue 9. 2023-09-27. PMID:37755735. |
oral administration of metronidazole resulted in a decrease in gaba, dopamine, and serotonin and an increase in ache in brain tissue. |
2023-09-27 |
2023-10-07 |
rat |
| Huijuan Li, Lu Wang, Junbao We. Observations on neurophysiological pattern and behavioural traits as death-feigning mechanism in Eucryptorrhynchus scrobiculatus (Coleoptera: Curculionidae). The Journal of experimental biology. 2023-09-22. PMID:37736810. |
our results reconstructed the death-feigning mechanism of e. scrobiculatus: when the effective stimuli point of arousal weevil received mechanical stimulation, the thoracoabdominal ganglion transmitted signals into the brain through the ventral nerve cord, and then the brain regulated da and 5-ht metabolic pathways, reducing the expression of dopamine (dar2), octopamine (oar1, oab2) receptor genes, finally inducing death feigning. |
2023-09-22 |
2023-10-07 |
Not clear |