| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiaoling Sun, Heng Li, Jing Lv, Weilin Shi, Yanfeng Bai, Ke Pan, Alice Che. Dopamine β-hydroxylase shapes intestinal inflammation through modulating T cell activation. Cellular immunology. vol 401-402. 2024-06-08. PMID:38850753. |
however, the role of dopamine beta-hydroxylase (dbh), an enzyme converting dopamine into norepinephrine, in modulating intestinal inflammation is not well defined. |
2024-06-08 |
2024-06-11 |
Not clear |
| Xiaofei Xu, Jingde Li, Mingjun Liu, Baoyan Zhan. Neuroprotective effect of Marrubiin against MPTP induced experimental Parkinson's disease in Male Wistar Rats. Toxicology mechanisms and methods. 2024-06-07. PMID:38847585. |
after marrubiin treatment, rats were trained, and tested for behavioral analyses like cognitive performance, open field test, rotarod test, grip strength test, beam walking test, the status of body weight, and striatal levels of neurotransmitters like dopamine, norepinephrine, serotonin, dopac, homovanillic acid, 5-hydroxy indole acetic acid, the status of oxidative stress markers like lpo, protein carbonyl content (pcc), xanthine oxidase (xo), and status of antioxidant enzyme levels like sod, cat, gpx in the striatum and hippocampal tissues, status of neuroinflammatory markers like tnf-α, il1β, il-6, and status of histological architecture in brain striatum were also analyzed. |
2024-06-07 |
2024-06-10 |
rat |
| Fatemeh Beigloo, Cameron J Davidson, Joseph Gjonaj, Shane A Perrine, Justin W Kenne. Individual differences in the boldness of female zebrafish are associated with alterations in serotonin function. The Journal of experimental biology. 2024-06-06. PMID:38842023. |
brain monoamines (i.e., serotonin, dopamine, and norepinephrine) have been found to play a role in a variety of behaviors related to risk taking. |
2024-06-06 |
2024-06-08 |
zebrafish |
| Vladimir Visocky, Carleigh J Turner, Matthew H Lowrie, Anthony Alibro, Fany Messanvi, Yogita Chudasam. Noradrenergic modulation of stress induced catecholamine release: Opposing influence of FG7142 and yohimbine. bioRxiv : the preprint server for biology. 2024-05-26. PMID:38766011. |
the basolateral amygdala (bla) and nucleus accumbens (nac) are stress sensitive brain areas that alter extracellular levels of norepinephrine (ne) and dopamine (da), respectively. |
2024-05-26 |
2024-05-27 |
rat |
| Xuelong Mi, Alex Bo-Yuan Chen, Daniela Duarte, Erin Carey, Charlotte R Taylor, Philipp N Braaker, Mark Bright, Rafael G Almeida, Jing-Xuan Lim, Virginia M Rutten, Wei Zheng, Mengfan Wang, Michael E Reitman, Yizhi Wang, Kira E Poskanzer, David A Lyons, Axel Nimmerjahn, Misha B Ahrens, Guoqiang Y. Fast, Accurate, and Versatile Data Analysis Platform for the Quantification of Molecular Spatiotemporal Signals. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38766026. |
we demonstrate applications across a range of biosensors (calcium, norepinephrine, atp, acetylcholine, dopamine), cell types (astrocytes, oligodendrocytes, microglia, neurons), organs (brains and spinal cords), animal models (zebrafish and mouse), and imaging modalities (confocal, two-photon, light sheet). |
2024-05-20 |
2024-05-27 |
mouse |
| Gao-Lin Qiu, Li-Jun Peng, Peng Wang, Zhi-Lai Yang, Ji-Qian Zhang, Hu Liu, Xiao-Na Zhu, Jin Rao, Xue-Sheng Li. Zoological research. vol 45. issue 3. 2024-05-20. PMID:38766749. |
here, we measured the dynamics of five neurotransmitters, including γ-aminobutyric acid, glutamate, norepinephrine, acetylcholine, and dopamine, in the medial prefrontal cortex and primary visual cortex of c57bl/6 mice through |
2024-05-20 |
2024-05-27 |
mouse |
| Tong Wu, Hanshuo Dong, Yin Liu, Zhenghua Cao, Li Su. Combination of UPLC-Q-TOF/MS and network pharmacology to reveal the mechanism of Chaihu-jia-Longgu-Muli decoction for treating vertigo with anxiety disorder. Biomedical chromatography : BMC. 2024-05-19. PMID:38763770. |
the results of the animal experiments showed that clmd decreased the levels of serotonin, norepinephrine and dopamine, alleviating the symptoms of vertigo and anxiety disorder in model rats. |
2024-05-19 |
2024-05-27 |
rat |
| Srikanth Jitte, Saritha Keluth, Priya Bisht, Pranay Wal, Sanjiv Singh, Krishna Murti, Nitesh Kuma. Obesity and Depression: Common Link and Possible Targets. CNS & neurological disorders drug targets. 2024-05-15. PMID:38747226. |
monoamines, including dopamine, serotonin, and norepinephrine, have been widely believed to have a function in emotions and appetite control. |
2024-05-15 |
2024-05-27 |
Not clear |
| Hoa Quynh Do, Elham Pirayesh, Garren Ferreira, Akash Pandhare, Zackary Ryan Gallardo, Michaela Janse. A bupropion modulatory site in Gloeobacter violaceus ligand-gated ion channel. Biophysical journal. 2024-04-28. PMID:38678367. |
bupropion inhibits dopamine and norepinephrine reuptake transporters and eukaryotic cation-conducting pentameric ligand-gated ion channels (plgics), such as nicotinic acetylcholine (nach) and serotonin type 3a (5-ht3a) receptors, at clinically relevant concentrations. |
2024-04-28 |
2024-04-30 |
Not clear |
| Eleni Agakidou, Ilias Chatziioannidis, Angeliki Kontou, Theodora Stathopoulou, William Chotas, Kosmas Sarafidi. An Update on Pharmacologic Management of Neonatal Hypotension: When, Why, and Which Medication. Children (Basel, Switzerland). vol 11. issue 4. 2024-04-27. PMID:38671707. |
anti-hypotensive treatment, which includes dopamine, dobutamine, epinephrine, norepinephrine, milrinone, vasopressin, terlipressin, levosimendan, and glucocorticoids, is a long-established intervention in neonates with arterial hypotension (ah). |
2024-04-27 |
2024-04-29 |
Not clear |
| Sixiang Chen, Xingyu Huang, Xintong Zhang, Chan Li, Yuan-Wei Zhan. A Conserved Intramolecular Ion-Pair Plays a Critical but Divergent Role in Regulation of Dimerization and Transport Function among the Monoamine Transporters. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612840. |
the monoamine transporters, including the serotonin transporter (sert), dopamine transporter (dat), and norepinephrine transporter (net), are the therapeutic targets for the treatment of many neuropsychiatric disorders. |
2024-04-13 |
2024-04-15 |
Not clear |
| Rajagopal Kalirajan, Khare Rishabh, Jupudi Srikanth, Modi Niharika, Negi Preeya, Islam Rezau. Molecular Docking, MM-GBSA, and Molecular Dynamics Approach: 5-MeO-DMT Analogues as Potential Antidepressants. Archives of Razi Institute. vol 78. issue 5. 2024-04-09. PMID:38590677. |
according to the monoamine-deficiency hypothesis, the underlying pathophysiology of depression is a deficiency of some neurotransmitters (serotonin, norepinephrine, or dopamine) in the central nervous system. |
2024-04-09 |
2024-04-11 |
Not clear |
| Jacob H Wilmot, Cassiano R A F Diniz, Ana P Crestani, Kyle R Puhger, Jacob Roshgadol, Lin Tian, Brian Joseph Wiltge. Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus. eLife. vol 12. 2024-04-09. PMID:38592773. |
although the lc is typically thought to modulate neural activity via the release of norepinephrine, several recent studies have suggested that it may also release dopamine into the hippocampus and other cortical regions. |
2024-04-09 |
2024-04-11 |
mouse |
| Jacob H Wilmot, Cassiano R A F Diniz, Ana P Crestani, Kyle R Puhger, Jacob Roshgadol, Lin Tian, Brian Joseph Wiltge. Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus. eLife. vol 12. 2024-04-09. PMID:38592773. |
in some cases, it appears that dopamine release from lc into the hippocampus may be more important for memory than norepinephrine. |
2024-04-09 |
2024-04-11 |
mouse |
| Jacob H Wilmot, Cassiano R A F Diniz, Ana P Crestani, Kyle R Puhger, Jacob Roshgadol, Lin Tian, Brian Joseph Wiltge. Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus. eLife. vol 12. 2024-04-09. PMID:38592773. |
we also demonstrate that lc activity increases both norepinephrine and dopamine content in the dorsal hippocampus and that the timing of hippocampal dopamine release during trace fear conditioning is similar to the timing of lc activity. |
2024-04-09 |
2024-04-11 |
mouse |
| Jacob H Wilmot, Cassiano R A F Diniz, Ana P Crestani, Kyle R Puhger, Jacob Roshgadol, Lin Tian, Brian Joseph Wiltge. Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus. eLife. vol 12. 2024-04-09. PMID:38592773. |
finally, we show that hippocampal dopamine is important for trace fear memory formation, while norepinephrine is not. |
2024-04-09 |
2024-04-11 |
mouse |
| Zhiwei Huang, Junhao Wu, Yihui Guan, Yumei Wei, Fang Xie, Yifeng She. PET/CT study of dopamine transporter (DAT) binding with the triple reuptake inhibitor toludesvenlafaxine in rats and humans. European journal of nuclear medicine and molecular imaging. 2024-04-08. PMID:38587645. |
despite the in vitro evidence that toludesvenlafaxine inhibits the reuptake of serotonin (5-ht), norepinephrine (ne) and dopamine (da), there is no in vivo evidence that toludesvenlafaxine binds to dat and increases da level, a mechanism thought to contribute to its favorable clinical performance. |
2024-04-08 |
2024-04-10 |
rat |
| Joseph S Lonstein, Taryn A Meinhardt, Pavlina Pavlidi, Nikos Kokras, Christina Dalla, Thierry D Charlier, Jodi L Pawlusk. Maternal probiotic Lactocaseibacillus rhamnosus HN001 treatment alters postpartum anxiety, cortical monoamines, and the gut microbiome. Psychoneuroendocrinology. vol 165. 2024-04-03. PMID:38569396. |
the results revealed that, even without pregnancy stress, hn001 reduced postpartum anxiety-related behavior, increased variability in behavioral fragmentation when dams interacted with pups, increased time away from pups, and decreased prefrontal cortex norepinephrine (ne), dopamine (da) and serotonin (5-ht). |
2024-04-03 |
2024-04-06 |
rat |
| M K P Joyce, S Yang, K Morin, A Duque, J Arellano, D Datta, M Wang, A F T Arnste. β1-adrenoceptor expression on GABAergic interneurons in primate dorsolateral prefrontal cortex: potential role in stress-induced cognitive dysfunction. Neurobiology of stress. vol 30. 2024-03-29. PMID:38550854. |
uncontrollable stress exposure impairs working memory and reduces the firing of dorsolateral prefrontal cortex (dlpfc) "delay cells", involving high levels of norepinephrine and dopamine release. |
2024-03-29 |
2024-03-31 |
Not clear |
| Lefika Bathobakae, Sacide S Ozgur, Rammy Bashir, Tyler Wilkinson, Phenyo Phuu, Ruhin Yuridullah, Gabriel Melki, Jessica Escobar, Sohail Qayyu. Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel Necrosis. Journal of investigative medicine high impact case reports. vol 12. 2024-03-28. PMID:38546011. |
cocaine is an indirect-acting sympathomimetic drug that inhibits norepinephrine and dopamine reuptake in the adrenergic presynaptic cleft. |
2024-03-28 |
2024-03-30 |
human |