| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jourdan H Parent, Kaitlin Cassady, William J Jagust, Anne S Berr. Pathological and neurochemical correlates of locus coeruleus functional network activity. Biological psychology. 2024-07-22. PMID:39038634. |
the locus coeruleus (lc) produces the neuromodulators norepinephrine and dopamine, and projects widely to subcortical and cortical brain regions. |
2024-07-22 |
2024-07-25 |
human |
| Mengjie Su, Wenjing Peng, Zhengyuan Ding, Yaqiu Zhou, Hui Gao, Qiyu Jiang, Chunmei Y. Multi-walled carbon nanotubes-metal-organic framework nanocomposite based sensor for the monitoring of multiple monoamine neurotransmitters in living cells. Bioelectrochemistry (Amsterdam, Netherlands). vol 160. 2024-07-17. PMID:39018612. |
the levels of monoamine neurotransmitters (mnts) including dopamine (da), adrenaline (adr), norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in cells are useful indicators to explore the pathogenesis of mnts-related diseases such as alzheimer's disease, parkinson's disease and depression. |
2024-07-17 |
2024-07-20 |
Not clear |
| Efthalia Angelopoulou, Anastasia Bougea, Alexandros Hatzimanolis, Nikolaos Scarmeas, Sokratis G Papageorgio. Unraveling the Potential Underlying Mechanisms of Mild Behavioral Impairment: Focusing on Amyloid and Tau Pathology. Cells. vol 13. issue 13. 2024-07-12. PMID:38995015. |
dysregulation of the hypothalamic-pituitary-adrenal (hpa) axis, disruption of neurotrophic factors, such as the brain-derived neurotrophic factor (bdnf), abnormal neuroinflammatory responses including the kynurenine pathway, dysregulation of transforming growth factor beta (tgf-β1), epigenetic alterations including micro-rna (mir)-451a and mir-455-3p, synaptic dysfunction, imbalance in neurotransmitters including acetylcholine, dopamine, serotonin, gamma-aminobutyric acid (gaba) and norepinephrine, as well as altered locus coeruleus (lc) integrity are some of the potential mechanisms connecting mbi with amyloid and tau pathology. |
2024-07-12 |
2024-07-14 |
Not clear |
| Arnav Paul, Diwakar Shukl. Oligomerization of Monoamine Transporters. Sub-cellular biochemistry. vol 104. 2024-07-04. PMID:38963486. |
the mat family functions using the electrochemical gradient of ions across the membrane and comprises three transporters, dopamine transporter (dat), serotonin transporter (sert), and norepinephrine transporter (net). |
2024-07-04 |
2024-07-10 |
Not clear |
| Fuwei Zhang, Ines Armando, Pedro A Jose, Chunyu Zeng, Jian Yan. G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets. Hypertension research : official journal of the Japanese Society of Hypertension. 2024-07-03. PMID:38961282. |
in organs such as the artery and kidney, hormones or neurotransmitters, such as angiotensin ii (ang ii), dopamine, epinephrine, and norepinephrine exert their functions via their receptors, with the ultimate effect of keeping normal vascular reactivity, normal body sodium, and normal blood pressure. |
2024-07-03 |
2024-07-10 |
Not clear |
| Nian-Sheng Tzeng, Jing-Yi Chung, Chen-Cheng Lin, Pao-Yun Cheng, Yia-Ping Li. Effects of Subchronic Buspirone Treatment on Depressive Profile in Socially Isolated Rats: Implication of Early Life Experience on 5-HT1A Receptor-Related Depression. Pharmaceuticals (Basel, Switzerland). vol 17. issue 6. 2024-06-27. PMID:38931384. |
efflux levels of 5-ht, dopamine (da), and norepinephrine (ne) were detected in the hippocampus by brain dialysis. |
2024-06-27 |
2024-06-29 |
rat |
| Guilherme Fusetto Veronesi, Alessandra Gabellone, Anneka Tomlinson, Marco Solmi, Christoph U Correll, Samuele Cortes. Treatments in the pipeline for attention-deficit/hyperactivity disorder (ADHD) in adults. Neuroscience and biobehavioral reviews. 2024-06-24. PMID:38914177. |
while several pharmacological and non-pharmacological interventions had evidence of superiority compared to the control condition from a single rct, centanafadine (norepinephrine, dopamine, and serotonin re-uptake inhibitor) was the only treatment with evidence of efficacy on adhd core symptoms (small effect size=0.28-0.40) replicated in at least one additional rct, alongside reasonable tolerability. |
2024-06-24 |
2024-06-27 |
Not clear |
| Olga Belousova, Anna Lopatina, Mikhail Melniko. The role of dopamine in the modulation of monocyte-induced Th17- and Th1-immune response in multiple sclerosis. International immunopharmacology. vol 137. 2024-06-22. PMID:38908080. |
we found, that both dopamine and norepinephrine modulate the production of th17- (il-23, il-1β, and il-6) and th1-promoting (il-12p70) cytokines by activated peripheral blood mononuclear cells or cd14 |
2024-06-22 |
2024-06-25 |
Not clear |
| Geeta Ilipilla, L Eugene Arnol. The role of adrenergic neurotransmitter reuptake inhibitors in the ADHD armamentarium. Expert opinion on pharmacotherapy. 2024-06-20. PMID:38900676. |
due to their effects on norepinephrine, dopamine, and serotonin neurotransmission, they benefit both adhd and comorbid disorders and have some other advantages including longer duration of action and fewer adverse effects compared to stimulants. |
2024-06-20 |
2024-06-23 |
Not clear |
| Ezio Carboni, Marcello Ibba, Elena Carboni, Anna Rosa Cart. Adolescent stress differentially modifies dopamine and norepinephrine release in the medial prefrontal cortex of adult rats. Progress in neuro-psychopharmacology & biological psychiatry. 2024-06-15. PMID:38879069. |
adolescent stress differentially modifies dopamine and norepinephrine release in the medial prefrontal cortex of adult rats. |
2024-06-15 |
2024-06-18 |
rat |
| Walaa G Abdelhamid, Noha A Mowaad, Gihan F Asaad, Asmaa F Galal, Sarah S Mohammed, Olfat E Mostafa, Doaa R Sadek, Lobna A Elkhate. The potential protective effect of Camellia Sinensis in mitigating monosodium glutamate-induced neurotoxicity: biochemical and histological study in male albino rats. Metabolic brain disease. 2024-06-13. PMID:38869783. |
msg administration resulted in significant neurotoxicity in rats that was revealed by the significant reduction of serum concentration of glutathione peroxidase (gpx) and nitric oxide (no), and the significant elevation of total antioxidant capacity (tac) accompanied by the significant reduction of levels of serum monoamines (dopamine, serotonin, and norepinephrine) and histological changes in the hippocampus area ca1, dentate gyrus, and cerebellar cortex and positive immunohistochemical staining of glial fibrillary acidic proteins (gfap) and calretinin. |
2024-06-13 |
2024-06-15 |
rat |
| Qiaoling Sun, Heng Li, Jing Lv, Weilin Shi, Yanfeng Bai, Ke Pan, Alice Che. Dopamine β-hydroxylase shapes intestinal inflammation through modulating T cell activation. Cellular immunology. vol 401-402. 2024-06-08. PMID:38850753. |
however, the role of dopamine beta-hydroxylase (dbh), an enzyme converting dopamine into norepinephrine, in modulating intestinal inflammation is not well defined. |
2024-06-08 |
2024-06-11 |
Not clear |
| Xiaofei Xu, Jingde Li, Mingjun Liu, Baoyan Zhan. Neuroprotective effect of Marrubiin against MPTP induced experimental Parkinson's disease in Male Wistar Rats. Toxicology mechanisms and methods. 2024-06-07. PMID:38847585. |
after marrubiin treatment, rats were trained, and tested for behavioral analyses like cognitive performance, open field test, rotarod test, grip strength test, beam walking test, the status of body weight, and striatal levels of neurotransmitters like dopamine, norepinephrine, serotonin, dopac, homovanillic acid, 5-hydroxy indole acetic acid, the status of oxidative stress markers like lpo, protein carbonyl content (pcc), xanthine oxidase (xo), and status of antioxidant enzyme levels like sod, cat, gpx in the striatum and hippocampal tissues, status of neuroinflammatory markers like tnf-α, il1β, il-6, and status of histological architecture in brain striatum were also analyzed. |
2024-06-07 |
2024-06-10 |
rat |
| Fatemeh Beigloo, Cameron J Davidson, Joseph Gjonaj, Shane A Perrine, Justin W Kenne. Individual differences in the boldness of female zebrafish are associated with alterations in serotonin function. The Journal of experimental biology. 2024-06-06. PMID:38842023. |
brain monoamines (i.e., serotonin, dopamine, and norepinephrine) have been found to play a role in a variety of behaviors related to risk taking. |
2024-06-06 |
2024-06-08 |
zebrafish |
| Vladimir Visocky, Carleigh J Turner, Matthew H Lowrie, Anthony Alibro, Fany Messanvi, Yogita Chudasam. Noradrenergic modulation of stress induced catecholamine release: Opposing influence of FG7142 and yohimbine. bioRxiv : the preprint server for biology. 2024-05-26. PMID:38766011. |
the basolateral amygdala (bla) and nucleus accumbens (nac) are stress sensitive brain areas that alter extracellular levels of norepinephrine (ne) and dopamine (da), respectively. |
2024-05-26 |
2024-05-27 |
rat |
| Xuelong Mi, Alex Bo-Yuan Chen, Daniela Duarte, Erin Carey, Charlotte R Taylor, Philipp N Braaker, Mark Bright, Rafael G Almeida, Jing-Xuan Lim, Virginia M Rutten, Wei Zheng, Mengfan Wang, Michael E Reitman, Yizhi Wang, Kira E Poskanzer, David A Lyons, Axel Nimmerjahn, Misha B Ahrens, Guoqiang Y. Fast, Accurate, and Versatile Data Analysis Platform for the Quantification of Molecular Spatiotemporal Signals. bioRxiv : the preprint server for biology. 2024-05-20. PMID:38766026. |
we demonstrate applications across a range of biosensors (calcium, norepinephrine, atp, acetylcholine, dopamine), cell types (astrocytes, oligodendrocytes, microglia, neurons), organs (brains and spinal cords), animal models (zebrafish and mouse), and imaging modalities (confocal, two-photon, light sheet). |
2024-05-20 |
2024-05-27 |
mouse |
| Gao-Lin Qiu, Li-Jun Peng, Peng Wang, Zhi-Lai Yang, Ji-Qian Zhang, Hu Liu, Xiao-Na Zhu, Jin Rao, Xue-Sheng Li. Zoological research. vol 45. issue 3. 2024-05-20. PMID:38766749. |
here, we measured the dynamics of five neurotransmitters, including γ-aminobutyric acid, glutamate, norepinephrine, acetylcholine, and dopamine, in the medial prefrontal cortex and primary visual cortex of c57bl/6 mice through |
2024-05-20 |
2024-05-27 |
mouse |
| Tong Wu, Hanshuo Dong, Yin Liu, Zhenghua Cao, Li Su. Combination of UPLC-Q-TOF/MS and network pharmacology to reveal the mechanism of Chaihu-jia-Longgu-Muli decoction for treating vertigo with anxiety disorder. Biomedical chromatography : BMC. 2024-05-19. PMID:38763770. |
the results of the animal experiments showed that clmd decreased the levels of serotonin, norepinephrine and dopamine, alleviating the symptoms of vertigo and anxiety disorder in model rats. |
2024-05-19 |
2024-05-27 |
rat |
| Srikanth Jitte, Saritha Keluth, Priya Bisht, Pranay Wal, Sanjiv Singh, Krishna Murti, Nitesh Kuma. Obesity and Depression: Common Link and Possible Targets. CNS & neurological disorders drug targets. 2024-05-15. PMID:38747226. |
monoamines, including dopamine, serotonin, and norepinephrine, have been widely believed to have a function in emotions and appetite control. |
2024-05-15 |
2024-05-27 |
Not clear |
| Hoa Quynh Do, Elham Pirayesh, Garren Ferreira, Akash Pandhare, Zackary Ryan Gallardo, Michaela Janse. A bupropion modulatory site in Gloeobacter violaceus ligand-gated ion channel. Biophysical journal. 2024-04-28. PMID:38678367. |
bupropion inhibits dopamine and norepinephrine reuptake transporters and eukaryotic cation-conducting pentameric ligand-gated ion channels (plgics), such as nicotinic acetylcholine (nach) and serotonin type 3a (5-ht3a) receptors, at clinically relevant concentrations. |
2024-04-28 |
2024-04-30 |
Not clear |