| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samiullah Burki, Zeba Gul Burki, - Mehjabeen, Ijaz Ahmed, Noor Jahan, Farah Owais, Nasim Tahir, Muhammad Kha. GC/MS assisted phytochemical analysis of Ajuga parviflora leaves extract along with anti-hepatotoxic effect against anti-tubercular drug induced liver toxicity in rat. Pakistan journal of pharmaceutical sciences. vol 33. issue 1(Supplementary). 2020-12-04. PMID:32122865. |
a. parviflora extract at 200 and 300 mg/kg in group c and d significantly reduced aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and bilirubin (p<0.001) as compare to group b (100mg/kg). |
2020-12-04 |
2023-08-13 |
rat |
| b' Iva Uzelac, Milo\\xc5\\xa1 Avramov, Tatjana \\xc4\\x8celi\\xc4\\x87, Elvira Vuka\\xc5\\xa1inovi\\xc4\\x87, Sne\\xc5\\xbeana Go\\xc5\\xa1i\\xc4\\x87-Dondo, Jelena Pura\\xc4\\x87, Danijela Koji\\xc4\\x87, Du\\xc5\\xa1ko Blagojevi\\xc4\\x87, \\xc5\\xbdeljko D Popovi\\xc4\\x8. Effect of Cold Acclimation on Selected Metabolic Enzymes During Diapause in The European Corn Borer Ostrinia nubilalis (Hbn.). Scientific reports. vol 10. issue 1. 2020-12-04. PMID:32493946.' |
to investigate metabolic changes during cold hardening, activities of four metabolic enzymes - citrate synthase (cs), lactate dehydrogenase (ldh), alanine aminotransferase (alt) and aspartate aminotransferase (ast) were measured in whole-body homogenates of pupae, non-diapausing and diapausing larvae acclimated to 5 °c, -3 °c and -16 °c. |
2020-12-04 |
2023-08-13 |
Not clear |
| Lingyue Liang, Zubin Huang, Na Li, Dongmei Wang, Li Ding, Haitao Shi, Meiling Hon. Effects of ammonia exposure on antioxidant function, immune response and NF-κB pathway in Chinese Strip-necked Turtle (Mauremys sinensis). Aquatic toxicology (Amsterdam, Netherlands). vol 229. 2020-12-04. PMID:33129562. |
in order to investigate the effects of ammonia exposure on the antioxidant defense, immune response, and nf-κb signaling pathway in chinese strip-necked turtle (mauremys sinensis), we designed two experimental groups (control and 6.45 mm ammonia), and sampled at 6 h, 24 h, 48 h, re 24 h (recover 24 h), and re 48 h. the results showed that the blood ammonia (ba) content was significantly increased when the turtles were subjected to ammonia, and the activities of cholinesterase (che) and aspartate aminotransferase (ast) in the serum also showed a significant upward trend. |
2020-12-04 |
2023-08-13 |
cat |
| Olivia Knittelfelder, Daniela Delago, Gabi Jakse, Sabine Reinisch, Richard Partl, Heidi Stranzl-Lawatsch, Wilfried Renner, Tanja Langsenlehne. The AST/ALT (De Ritis) Ratio Predicts Survival in Patients with Oral and Oropharyngeal Cancer. Diagnostics (Basel, Switzerland). vol 10. issue 11. 2020-11-29. PMID:33228184. |
aminotransaminases, including aspartate aminotransaminase (ast) and alanine aminotransaminase (alt), are strongly involved in cancer cell metabolism and have been associated with prognosis in different types of cancer. |
2020-11-29 |
2023-08-13 |
Not clear |
| Hyun Hwangbo, Min Yeong Kim, Seon Yeong Ji, So Young Kim, Hyesook Lee, Gi-Young Kim, Cheol Park, Young-Sam Keum, Su Hyun Hong, Jaehun Cheong, Yung Hyun Cho. Auranofin Attenuates Non-Alcoholic Fatty Liver Disease by Suppressing Lipid Accumulation and NLRP3 Inflammasome-Mediated Hepatic Inflammation In Vivo and In Vitro. Antioxidants (Basel, Switzerland). vol 9. issue 11. 2020-11-28. PMID:33114221. |
auranofin significantly decreased the body weight, epididymal fat weight, serum aspartate aminotransferase (ast), and glucose, as well as the serum triglyceride, cholesterol, and low-density lipoprotein cholesterol levels as compared to the hfd group. |
2020-11-28 |
2023-08-13 |
mouse |
| Rui-Bo Jia, Zhao-Rong Li, Juan Wu, Zhi-Rong Ou, Qiyuan Zhu, Baoguo Sun, Lianzhu Lin, Mouming Zha. Physicochemical properties of polysaccharide fractions from Sargassum fusiforme and their hypoglycemic and hypolipidemic activities in type 2 diabetic rats. International journal of biological macromolecules. vol 147. 2020-11-26. PMID:31899245. |
regarding to hypoglycemic and hypolipidemic effects, oral administration of sfps prominently restrained loss of body weight and increase of water intake, and also significantly controlled the increase of levels of fasting blood glucose, triglyceride (tg), total cholesterol (tc), low density lipoprotein cholesterol (ldl-c), uric acid (ua), urea nitrogen (bun), alanine aminotransferase (alt) and aspartate aminotransferase (ast) of diabetic rats, and sfp-2 showed better effects in controlling fasting blood glucose, alt, ua and bun levels. |
2020-11-26 |
2023-08-13 |
rat |
| Ji Hye Yang, Chang-Su Na, Sam Seok Cho, Kyu Min Kim, Ji Hyun Lee, Xi-Qiang Chen, Sae Kwang Ku, Il Je Cho, Eun Joo Kim, Je Hyeon Lee, Sung Hwan K. Hepatoprotective Effect of Neoagarooligosaccharide via Activation of Nrf2 and Enhanced Antioxidant Efficacy. Biological & pharmaceutical bulletin. vol 43. issue 4. 2020-11-26. PMID:32009027. |
moreover, naos inhibited acetaminophen (apap)-induced serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) and significantly decreased hepatocyte degeneration and inflammatory cell infiltration. |
2020-11-26 |
2023-08-13 |
mouse |
| Jinshan Wang, Wentao Jian. The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-11-24. PMID:32026851. |
the hepg2 human hepatocellular carcinoma cells were treated with or without rki-1447 for 2 h and treated with oleic acid for 24 h. results in the mouse model of nafld, rki-1447 reduced insulin resistance and the levels of alanine aminotransferase (alt), aspartate transaminase (ast), total cholesterol, triglyceride, interleukin-6 (il-6), tumor necrosis factor-alpha (tnf-alpha), malondialdehyde (mda), and superoxide dismutase (sod). |
2020-11-24 |
2023-08-13 |
mouse |
| Yanyan Zhao, Yunjun Yan, Liqiang Xie, Lixiao Wang, Yaojia He, Xiang Wan, Qingju Xu. Long-term environmental exposure to microcystins increases the risk of nonalcoholic fatty liver disease in humans: A combined fisher-based investigation and murine model study. Environment international. vol 138. 2020-11-20. PMID:32187572. |
the indices of aspartate aminotransferase (ast)/alanine aminotransferase (alt), triglyceride (tg), globulin (glb), and lactate dehydrogenase (ldh) had close positive associations with mc contamination, indicating that both liver damage and lipid metabolism dysfunction were induced by chronic mc exposure. |
2020-11-20 |
2023-08-13 |
mouse |
| J B Rajesh, S Rajkhowa, U Dimri, H Prasad, N H Mohan, L Hmar, K Sarma, G E Chethan, P Behera, G Jaganmohanarao, S Behera, Zosangpui. Haemato-biochemical alterations and oxidative stress associated with naturally occurring porcine circovirus2 infection in pigs. Tropical animal health and production. vol 52. issue 5. 2020-11-19. PMID:32125595. |
alanine transaminase (alt), aspartate transaminase (ast), gamma-glutamyl transferase (ggt) and alkaline phosphatase (alp) were measured. |
2020-11-19 |
2023-08-13 |
Not clear |
| Shimaa E Ali, Amr A A Gamil, Ida Skaar, Øystein Evensen, Harrison Charo-Karis. Efficacy and safety of boric acid as a preventive treatment against Saprolegnia infection in Nile tilapia (Oreochromis niloticus). Scientific reports. vol 9. issue 1. 2020-11-13. PMID:31784693. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) enzyme levels indicated reduction in systemic tissue damage associated with saprolegnia infection. |
2020-11-13 |
2023-08-13 |
Not clear |
| Aleksandra Kołota, Dominika Głąbska, Michał Oczkowski, Joanna Gromadzka-Ostrowsk. Oxidative Stress Parameters in the Liver of Growing Male Rats Receiving Various Alcoholic Beverages. Nutrients. vol 12. issue 1. 2020-11-13. PMID:31935882. |
afterwards, the activities of alcohol dehydrogenase (adh), alanine aminotransferase (alt), and aspartate aminotransferase (ast), as well as levels of cytochrome p450-2e1 (cyp2e1), thiobarbituric acid-reactive substances (tbars), protein carbonyl groups, tumor necrosis factor-α (tnf-α), and interleukine-10 (il-10) were measured in liver homogenates. |
2020-11-13 |
2023-08-13 |
rat |
| Zhibin Lin, Xuan Zhang, Jianlin Wang, Wei Liu, Qi Liu, Yuchen Ye, Bin Dai, Dongnan Guo, Pengcheng Zhang, Peijun Yang, Ruohan Zhang, Lin Wang, Kefeng Do. Translationally controlled tumor protein promotes liver regeneration by activating mTORC2/AKT signaling. Cell death & disease. vol 11. issue 1. 2020-11-11. PMID:31974368. |
lastly, the increasing rate of serum tctp positively correlated to the recovery of alanine aminotransferase (alt) and aspartate aminotransferase (ast) after liver resection in humans. |
2020-11-11 |
2023-08-13 |
mouse |
| Fang-Hsin Chen, Ching-Fang Yu, Chung-Lin Yang, Yu-Chun Lin, Gigin Lin, Chun-Chieh Wang, Huang-Ping Yu, Jui Fang, Ning-Fang Chang, Ji-Hong Hon. Multimodal imaging reveals transient liver metabolic disturbance and sinusoidal circulation obstruction after a single administration of ketamine/xylazine mixture. Scientific reports. vol 10. issue 1. 2020-11-10. PMID:32108154. |
after the k/x injection, aspartate aminotransferase (ast) in serum was significantly elevated from 3 to 48 h. |
2020-11-10 |
2023-08-13 |
Not clear |
| H U Fei-Fei, Hao Zhan-Xia, Zhang Shao-Bo, Sheng Yu-Chen, J I Li-L. [Study on improvement provided by water extracts of Polygoni Multiflori Radix and Polygoni Multiflori Radix Praeparata on non-alcoholic steatohepatitis in mice induced by MCD]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 19. 2020-11-10. PMID:33164440. |
serum alanine aminotransferase(alt) and aspartate aminotransferase(ast) activities were detected; liver histopathological evaluation and nafld activity score(nas) calculation were conducted, and the levels of reactive oxygen species(ros) in liver tissues were analyzed. |
2020-11-10 |
2023-08-13 |
mouse |
| Kuang Zi-Yu, Jiang Feng, W U Jia-Xu, Liu Hui-Mi. [Network Meta-analysis of traditional Chinese medicine in treating drug-induced liver injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 19. 2020-11-10. PMID:33164442. |
in terms of reducing aspartate aminotransferase(ast), shuganning, hugan jiedu recipe, wucao baogan recipe, liuwei wuling tablets and sini shugan decoction were all superior to western medicine. |
2020-11-10 |
2023-08-13 |
Not clear |
| Jianhua Ming, Jinyun Ye, Yixiang Zhang, Qiyou Xu, Xia Yang, Xianping Shao, Jun Qiang, Pao X. Optimal dietary curcumin improved growth performance, and modulated innate immunity, antioxidant capacity and related genes expression of NF-κB and Nrf2 signaling pathways in grass carp (Ctenopharyngodon idella) after infection with Aeromonas hydrophila. Fish & shellfish immunology. vol 97. 2020-11-09. PMID:31881329. |
moreover, optimal dietary curcumin increased the activities of lysozyme (lyz) and acid phosphatase (acp), and complement 3 (c3) and c4 levels, decreased alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities in serum of grass carp after injection with a. hydrophila (p < 0.05). |
2020-11-09 |
2023-08-13 |
cat |
| Jia-Ling Guo, Wen-Ming Kuang, Yun-Fei Zhong, Yue-Lang Zhou, Yong-Jun Chen, Shi-Mei Li. Effects of supplemental dietary bile acids on growth, liver function and immunity of juvenile largemouth bass（Micropterus salmoides）fed high-starch diet. Fish & shellfish immunology. vol 97. 2020-11-09. PMID:31899355. |
the activities of alanine aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase (alp) and glucose contents in plasma of sb group were significantly lower than hs treatment, whereas the content of triglyceride (tg) and total cholesterol (tc) in plasma were significantly higher than hs treatment. |
2020-11-09 |
2023-08-13 |
cat |
| Chongjun Zhao, Mingshuang Wang, Zhe Jia, Erwen Li, Xia Zhao, Farong Li, Ruichao Li. Similar hepatotoxicity response induced by Rhizoma Paridis in zebrafish larvae, cell and rat. Journal of ethnopharmacology. vol 250. 2020-11-04. PMID:31786445. |
rhizoma paridis could diminish cell activity and cell proliferation, brought on cell apoptosis and elevated the levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) compared with the control group, as evaluated in cell cultures. |
2020-11-04 |
2023-08-13 |
rat |
| J Li, R J Li, X Zhao, H Q Li. The role of Sigma-1 receptor agonist in hepatic ischemiareperfusion injury. Journal of biological regulators and homeostatic agents. vol 34. issue 3. 2020-11-04. PMID:32660197. |
this effect was manifested by decreased serum levels of alanine aminotransferase (ast), aspartate aminotransferase (alt), myeloperoxidase (mpo), and supernatant level of lactate dehydrogenase (ldh), decreased endothelial glycocalyx shedding indexed by decreased serum levels of heparan sulfate and syndecan-1, slightly improved liver histology and reduced metalloproteinase-9 expression. |
2020-11-04 |
2023-08-13 |
mouse |