| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M A Aldouri, B Wonke, A V Hoffbrand, D M Flynn, M Laulicht, L A Fenton, P J Scheuer, C C Kibbler, C A Allwood, D Brow. Iron state and hepatic disease in patients with thalassaemia major, treated with long term subcutaneous desferrioxamine. Journal of clinical pathology. vol 40. issue 11. 1988-02-10. PMID:3121679. |
the results were compared with serum ferritin concentration and aspartate transaminase (ast) activity and with hepatitis b virus serology. |
1988-02-10 |
2023-08-11 |
Not clear |
| G J Beckett, P C Hayes, A J Hussey, I A Bouchier, J D Haye. Plasma glutathione S-transferase measurements in patients with alcoholic cirrhosis. Clinica chimica acta; international journal of clinical chemistry. vol 169. issue 1. 1988-01-20. PMID:3677438. |
hepatocellular damage has been assessed in 54 patients with biopsy proven alcoholic cirrhosis by measuring the activity of aspartate aminotransferase (ast) and the concentrations of glutathione s-transferase b1b1 (gst b1b1) and b2b2 (gst b2b2) in serum. |
1988-01-20 |
2023-08-11 |
Not clear |
| W R Yates, F Petty, K Brow. Risk factors for alcohol hepatotoxicity among male alcoholics. Drug and alcohol dependence. vol 20. issue 2. 1988-01-14. PMID:2890507. |
significant gamma glutamyl transferase (ggt) elevations were found in patients consuming an average of 7 beers/day for 5 years, and significant aspartate aminotransferase (ast) elevations were found in patients consuming a threshold of 12 beers/day for 10 years. |
1988-01-14 |
2023-08-11 |
Not clear |
| M A Basinger, M M Jones, W D Craft, E M Walker, M M Sander. Chelating-agent suppression of cadmium-induced hepatotoxicity. Journal of toxicology and environmental health. vol 22. issue 3. 1987-12-23. PMID:2890768. |
some effect on serum enzyme levels was found even when the interval between administration of cadmium chloride and that of the antagonist was as great as 4 h. the enzymes examined included aspartate aminotransferase (ast), gamma-glutamyl transpeptidase (ggt), alanine aminotransferase (sgpt), and alkaline phosphatase (ap). |
1987-12-23 |
2023-08-11 |
Not clear |
| S V Dange, P S Patki, V M Bapat, D S Shrotr. Effect of 'Arogyavardhini' against carbon tetrachloride induced hepatic damage in albino rats. Indian journal of physiology and pharmacology. vol 31. issue 1. 1987-12-14. PMID:3666871. |
the protective effect was assessed from serum aspartate transaminase (ast) and alkaline phosphatase levels and from histopathological changes in liver. |
1987-12-14 |
2023-08-11 |
rat |
| A Kumar, H N Pandey, G Sharma, D N Pandey, B K Su. Urinary aspartate transaminase (AST) activity and detection of its inhibitors in normal urine. Indian journal of physiology and pharmacology. vol 31. issue 1. 1987-12-14. PMID:3666869. |
urinary aspartate transaminase (ast) activity and detection of its inhibitors in normal urine. |
1987-12-14 |
2023-08-11 |
human |
| G C Moses, G O Lightle, J F Tuckerman, A R Henderso. A clinical evaluation of the Cobas Fara clinical chemistry analyzer for some routine serum enzymes and glucose. American journal of clinical pathology. vol 88. issue 5. 1987-12-14. PMID:3673942. |
total day-to-day imprecision (within plus between run) was less than 5% (coefficient of variation) for aspartate and alanine aminotransferases (ast; enzyme commission classification number [ec] ec 2.6.1.1; and alt; ec 2.6.1.2); alkaline phosphatase (ap; ec 3.1.3.1); gamma-glutamyltransferase (ggt; ec 2.3.1.2); lactate dehydrogenase (ld; ec 1.1.1.17); creatine kinase (ck; ec 2.7.3.1); and glucose assays. |
1987-12-14 |
2023-08-11 |
Not clear |
| P Martin-Sanz, C Cascales, A Gómez, D N Brindley, M Cascale. Effect of a rhodium complex on alterations of hepatic function in thioacetamide-induced hyperplastic noduligenesis in rats. Carcinogenesis. vol 8. issue 11. 1987-12-07. PMID:2889538. |
the rise in alkaline phosphatase (alp), leucine aminopeptidase (lap), gamma-glutamyl transferase (ggt) and the unchanged activities in the aspartate and alanine aminotransferases (ast, alt) in plasma of tam-treated rats indicated that the disease induced by this substance can be considered as a chronic obstructive biliary disease with indices of cell proliferation and tumors. |
1987-12-07 |
2023-08-11 |
rat |
| N M Knufman, A van der Laarse, H W Vliegen, C J Brinkma. Quantification of myocardial necrosis and cardiac hypertrophy in isoproterenol-treated rats. Research communications in chemical pathology and pharmacology. vol 57. issue 1. 1987-11-25. PMID:2959998. |
to assess the extent of necrosis we measured myocardial activities of creatine kinase (ck) and aspartate aminotransferase (ast) in the first days after iso-treatment. |
1987-11-25 |
2023-08-11 |
rat |
| J A Engelhardt, W W Carlton, A H Rebar, A W Haye. Rubratoxin B mycotoxicosis in the Syrian hamster. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 25. issue 9. 1987-11-18. PMID:3653822. |
serum activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt) and serum concentrations of total and indirect bilirubin were increased by 8 hr after dosing and returned to control values by the end of the test period. |
1987-11-18 |
2023-08-11 |
Not clear |
| L J Scully, R Shein, P Karayiannis, J A McDonald, H C Thoma. Lymphoblastoid interferon therapy of chronic HBV infection. A comparison of 12 vs. 24 weeks of thrice weekly treatment. Journal of hepatology. vol 5. issue 1. 1987-11-06. PMID:3655310. |
variables associated with response included high ast (aspartate transaminase), short duration of disease and previous history of acute hepatitis. |
1987-11-06 |
2023-08-11 |
Not clear |
| M L Berger, T Sozer. Rapid halogenated hydrocarbon toxicity in isolated hepatocytes is mediated by direct solvent effects. Toxicology. vol 45. issue 3. 1987-10-05. PMID:3629614. |
release of aspartate aminotransferase (ast) activity was rapid and concentration-dependent. |
1987-10-05 |
2023-08-11 |
rat |
| N I Eldirdiri, H B Suliman, A M Shommei. Normal serum activities of some diagnostic enzymes in dromedary camel in Sudan. Veterinary research communications. vol 11. issue 3. 1987-09-30. PMID:2888228. |
76 adult camel (30 males and 46 females) sera were surveyed for the normal activities of alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast), creatine phospho-kinase (cpk), gamma-glutamyl transpeptidase (ggt) and lactate dehydrogenase (ldh). |
1987-09-30 |
2023-08-11 |
Not clear |
| M G Neuman, D Cotariu, J Eshchar, L Barr-Nea, J S Isha. Liver damage induced by Oriental hornet venom sac extract at the level of subcellular fractions. Clinical biochemistry. vol 20. issue 2. 1987-09-02. PMID:3608144. |
serum activities of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), and gamma-glutamyl transferase (ggt) were measured. |
1987-09-02 |
2023-08-11 |
rat |
| P Vaagenes, J Kjekshus, E Sivertsen, G Sem. Temporal pattern of enzyme changes in cerebrospinal fluid in patients with neurologic complications after open heart surgery. Critical care medicine. vol 15. issue 8. 1987-09-01. PMID:3608528. |
we serially measured creatine kinase (ck), lactate dehydrogenase, aspartate aminotransferase (ast) and lactate from the lumbar cerebrospinal fluid in 14 patients with neurologic complications after open heart surgery with cardiopulmonary bypass (cpb). |
1987-09-01 |
2023-08-11 |
Not clear |
| A Chiarelli, A Casadei, E Pornaro, L Siliprandi, F Mazzolen. Alanine and aspartate aminotransferase serum levels in burned patients: a long-term study. The Journal of trauma. vol 27. issue 7. 1987-09-01. PMID:3612854. |
increased alanine and aspartate aminotransferase (alt and ast) serum levels are usually considered expressions of cellular necrosis, especially in hepatocytes. |
1987-09-01 |
2023-08-11 |
Not clear |
| S C Litin, J F O'Brien, S Pruett, R W Forsman, M F Burritt, L G Bartholomew, W P Baldu. Macroenzyme as a cause of unexplained elevation of aspartate aminotransferase. Mayo Clinic proceedings. vol 62. issue 8. 1987-08-27. PMID:3600038. |
aspartate aminotransferase (ast) can exist as a macroenzyme by forming a complex with an immunoglobulin. |
1987-08-27 |
2023-08-11 |
Not clear |
| D A Adelekan, A D Adekile, D I Thurnha. Dependence of pyridoxine metabolism on riboflavin status in sickle cell patients. The American journal of clinical nutrition. vol 46. issue 1. 1987-08-07. PMID:3604973. |
aspartate transaminase (ast) activities in scd patients were double those in control subjects. |
1987-08-07 |
2023-08-11 |
human |
| W O Young, P J Goldschmidt-Clermont, D L Emerson, W M Lee, D J Jollow, R M Galbrait. Correlation between extent of liver damage in fulminant hepatic necrosis and complexing of circulating group-specific component (vitamin D-binding protein). The Journal of laboratory and clinical medicine. vol 110. issue 1. 1987-07-29. PMID:3598340. |
liver damage was monitored by aspartate aminotransferase (ast) activity and by histologic examination, and serum gc was analyzed by polyacrylamide gel electrophoresis (page) and transblotting with anti-gc. |
1987-07-29 |
2023-08-11 |
Not clear |
| P R Donald, J F Schoeman, A O'Kenned. Hepatic toxicity during chemotherapy for severe tuberculosis meningitis. American journal of diseases of children (1960). vol 141. issue 7. 1987-07-22. PMID:2884866. |
of 33 children observed for at least eight weeks, only five (15%) had normal serum aspartate aminotransferase (ast), alanine aminotransferase (alt), and gamma-glutamyl transferase levels throughout, but in only three patients were ast or alt values greater than 200 u/l, and enzyme levels tended to normalize toward the end of the period. |
1987-07-22 |
2023-08-11 |
Not clear |