| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D K Garg, R N Goya. Haematological and hepatotoxic effects of silken styles of corn in albino rats. Journal of applied toxicology : JAT. vol 12. issue 5. 1992-12-24. PMID:1447482. |
the following haematological values were significantly reduced on the 7th and 21st day following extract administration: haemoglobin (hb), red blood corpuscles (rbc), clotting time (ct), mean corpuscular volume (mcv), haematocrit (ht), serum glucose, blood urea nitrogen (bun), cholesterol, aspartate transaminase (ast), alanine transaminase (alt), calcium, total protein, total albumin and total acid phosphatase; and white blood corpuscles (wbc), mean corpuscular haemoglobin (mch), mean corpuscular haemoglobin concentration (mchc), alkaline phosphatase and creatinine increased. |
1992-12-24 |
2023-08-11 |
rat |
| A Richter, C Gerdes, W Lösche. Atypical reactions to halothane in a subgroup of homozygous malignant hyperthermia(MH)-susceptible pigs: indication of a heterogenous genetic basis for the porcine syndrome. DTW. Deutsche tierarztliche Wochenschrift. vol 99. issue 10. 1992-12-23. PMID:1425316. |
the typical mh was characterized by sudden appearance of tachycardia, muscle rigidity with typical extension of the hindlimbs, increase of body temperature, acidosis-caused by rapid increase of co2 and lactate production-, hyperkalaemia and increased activity of creatine kinase (ck) and aspartate transaminase (ast). |
1992-12-23 |
2023-08-11 |
Not clear |
| N P Skakun, O E Tabachu. [The comparative action of isoniazid, rifampicin and ethambutol on liver function]. Eksperimental'naia i klinicheskaia farmakologiia. vol 55. issue 2. 1992-12-22. PMID:1422454. |
this is supported by activation of aspartate and alanine aminotransferases, (alt and ast), alkaline phosphatase in blood serum and acid phosphatase in the liver, by a decrease of the activity of na(+)-, k(+)-atpase, succinate dehydrogenase and cytochromoxidase in the liver, lowering of the rate of bile secretion, excretion of bile acids, bilirubin and cholesterol with bile. |
1992-12-22 |
2023-08-11 |
rat |
| K Yoneda, Y Katayama, T Koike, I Tanimiz. A homogeneous assay system of aspartate aminotransferase iso-enzymes using proteases and application for clinical evaluation of myocardial infarction. Journal of clinical laboratory analysis. vol 6. issue 6. 1992-12-22. PMID:1432361. |
we designed a rapid, homogeneous assay for human aspartate aminotransferase (ast) isoenzymes, by a selective proteolysis of soluble ast (s-ast), using chymotrypsin and protease 401. |
1992-12-22 |
2023-08-11 |
human |
| S Yamini, N Carswell, O E Michaelis, B Szepes. Adaptation in enzyme (metabolic) pathways to obesity, carbohydrate diet and to the occurrence of NIDDM in male and female SHR/N-cp rats. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 16. issue 10. 1992-12-17. PMID:1330956. |
liver glucose-6-phosphatase (g6pase), fructose 1,6-bisphosphatase (fbpase), phosphoenolpyruvate carboxykinase (pepck), glucose-6-phosphate dehydrogenase (g6pdh), 6-phosphogluconate dehydrogenase (6pgdh), malic enzyme (me), phosphofructokinase (pfk), glucokinase (gk), aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels (per total liver capacity) were significantly affected by phenotype (obese > lean). |
1992-12-17 |
2023-08-11 |
rat |
| A van der Laarse, L Hollaar, S W Kok, S van den Eijnde, J H Souverijn, P J Hoedemaeker, A V Bruschk. Myocardial creatine kinase-MB concentration in normal and explanted human hearts and released from hearts of patients with acute myocardial infarction. Clinical physiology and biochemistry. vol 9. issue 1. 1992-12-17. PMID:1424434. |
by calculation of cumulatively released amounts of ck-mb and cumulatively released activities of ck, aspartate aminotransferase (ast) and alpha-hydroxybutyrate dehydrogenase (hbdh), we obtained values of the proportions in which these quantities were released from the myocardium. |
1992-12-17 |
2023-08-11 |
human |
| R J Nuviala, L Roda, M G Lapieza, B Boned, A Gine. Serum enzymes activities at rest and after a marathon race. The Journal of sports medicine and physical fitness. vol 32. issue 2. 1992-12-10. PMID:1434588. |
enzymes such as aspartate aminotransferase (ast) and lactate dehydrogenase (ldh), which are widely distributed in the tissues, were found to have undergone more marked variations and these could not be related to the changes in the volume of the plasma, while in enzymes of muscular origin such as aldolase (ald), creatine kinase (ck) and its cardiac isoenzyme (ck-mb), notable increases were observed due to the muscular injury suffered. |
1992-12-10 |
2023-08-11 |
Not clear |
| M V Berezkin, E N Gratsinskiĭ, V F Kudinova, A N Batygov, L E Ponomareva, O A Prikazchikova, G N Zhukov. [Seasonal and circadian fluctuations in blood biochemical indicators in mice in natural conditions and exposed to constant light]. Biulleten' eksperimental'noi biologii i meditsiny. vol 114. issue 7. 1992-12-01. PMID:1421318. |
the fluctuations of activity of aspartate aminotransferase (ast) and alanine aminotransferase (alt) and those of the levels of protein, glucose, cholesterol, bilirubin, creatinine, blood urea nitrogen, k+, cl-, na+ in blood plasma of mice in natural conditions (nc) and exposed to constant light (cl) were studied in different seasons of the year (in january, april, july, october) on days 18, 24, 6 (at 12 o'clock). |
1992-12-01 |
2023-08-11 |
mouse |
| G A Brazeau, M Mathew, R K Entriki. Serum and organ indices of the mdx dystrophic mouse. Research communications in chemical pathology and pharmacology. vol 77. issue 2. 1992-11-27. PMID:1439189. |
increases in serum lactate dehydrogenase (ldh), alkaline phosphatase (ap), aspartate transaminase (ast), and cholesterol levels, combined with an increase in liver weight and a decrease in cytochrome p-450, suggests the possibility of hepatic dysfunction. |
1992-11-27 |
2023-08-11 |
mouse |
| S N Lichtman, E E Okoruwa, J Keku, J H Schwab, R B Sarto. Degradation of endogenous bacterial cell wall polymers by the muralytic enzyme mutanolysin prevents hepatobiliary injury in genetically susceptible rats with experimental intestinal bacterial overgrowth. The Journal of clinical investigation. vol 90. issue 4. 1992-11-13. PMID:1401067. |
buffer treatment, ursodeoxycholic acid, prednisone, methotrexate, and cyclosporin a failed to prevent sbbo-induced injury as demonstrated by increased plasma aspartate aminotransferase (ast) and elevated histology scores. |
1992-11-13 |
2023-08-11 |
rat |
| P H Lolekha, P Nitipaichi. User-defined serum aspartate and alanine aminotransferase, cholesterol, triglycerides, urea, and uric acid for the Beckman synchron CX 4/5 using Ames Sera-Pak reagents. Journal of clinical laboratory analysis. vol 6. issue 5. 1992-11-13. PMID:1403344. |
beckman aspartate aminotransferase (ast), alanine aminotransferase (alt), cholesterol, triglycerides, urea, and uric acid liquid reagents for synchron cx 4/5 (48, 48, 25, 60, 26, and 30 cents us/test, respectively) are expensive. |
1992-11-13 |
2023-08-11 |
Not clear |
| H Reckendorfer, H Burgmann, M Sperlich, G L Tüchy, W Feigl, P G Spieckermann, M Weindlmayr-Göttel, S Schwar. Hepatotoxicity testing of atracurium and laudanosine in the isolated, perfused rat liver. British journal of anaesthesia. vol 69. issue 3. 1992-11-05. PMID:1389846. |
despite using extremely high concentrations of these substances, we could not detect, biochemically (release of ldh or aspartate amino-transferase (ast)) or histologically, any signs of liver cell damage. |
1992-11-05 |
2023-08-11 |
rat |
| H Kobayashi, T Kurokawa, S Kitahara, T Nonami, A Harada, A Nakao, S Sugiyama, T Ozawa, H Takag. The effects of gamma-glutamylcysteine ethyl ester, a prodrug of glutathione, on ischemia-reperfusion-induced liver injury in rats. Transplantation. vol 54. issue 3. 1992-10-29. PMID:1412719. |
leakages of aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), and adenine nucleotides into the hepatic vein after reperfusion were also measured. |
1992-10-29 |
2023-08-11 |
rat |
| C A Brass, J M Crawford, J Narciso, J L Golla. Hypoxic liver injury and the ameliorating effects of fructose: the "glucose paradox" revisited. The American journal of physiology. vol 263. issue 3 Pt 1. 1992-10-29. PMID:1415541. |
with the use of a hypoxically perfused isolated rat liver model, cellular injury, as reflected by aspartate aminotransferase (ast) release, was significantly greater in the liver of fasted (mean ast 489 u/g liver at 3 h) than fed (40 u/g) animals. |
1992-10-29 |
2023-08-11 |
rat |
| R Cywes, P D Greig, J R Sanabria, P A Clavien, G A Levy, P R Harvey, S M Strasber. Effect of intraportal glucose infusion on hepatic glycogen content and degradation, and outcome of liver transplantation. Annals of surgery. vol 216. issue 3. 1992-10-26. PMID:1417173. |
despite wide variation in postoperative aspartate aminotransferase (ast) levels among recipients in both groups, the difference in peak postoperative ast levels approached significance (p = 0.06). |
1992-10-26 |
2023-08-11 |
human |
| C H Kuo, D I Tai, C S Chang-Chien, C K Lan, S S Chiou, Y F Lia. Liver biochemical tests and dengue fever. The American journal of tropical medicine and hygiene. vol 47. issue 3. 1992-10-15. PMID:1355950. |
abnormal levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), bilirubin, alkaline phosphatase, and gamma-glutamyl transpeptidase (g-gt) were observed in 93.3%, 82.2%, 7.2%, 16.3% and 83.0% of the patients, respectively. |
1992-10-15 |
2023-08-11 |
Not clear |
| E Berman, D E House, J W Allis, J E Simmon. Hepatotoxic interactions of ethanol with allyl alcohol or carbon tetrachloride in rats. Journal of toxicology and environmental health. vol 37. issue 1. 1992-10-15. PMID:1522609. |
there was no histopathological evidence of hepatic damage with ethanol alone, and no effect on hepatic cytochrome p-450 and glutathione levels or on serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alk). |
1992-10-15 |
2023-08-11 |
rat |
| J Drsata, I M Hais, P Malo. Interaction of Z-4,4-bis(4-ethylphenyl)-2,3-dibromo-2-butenoic acid with aminotransferases: changes in absorption and circular dichroism spectra. Drug metabolism and drug interactions. vol 9. issue 3-4. 1992-10-14. PMID:1824079. |
the influence of z-4,4-bis(4-ethylphenyl)-2,3-dibromo-2-butenoic acid, the compound originally synthetized as a cytostatic edikron and showing inhibitory effect on several pyridoxal enzymes, on absorption and circular dichroism spectra of alanine and aspartate aminotransferases (alt, ast) in the region of coenzyme absorption characteristics was studied. |
1992-10-14 |
2023-08-11 |
Not clear |
| M Netopilová, J Veselá, J Drsat. Influence of 5-[2-(N,N-dimethylamino)ethoxy]-7-oxo-7H-benzo(C)fluorene hydrochloride (benflurone) on the activity of rat liver aspartate and alanine aminotransferases. Drug metabolism and drug interactions. vol 9. issue 3-4. 1992-10-14. PMID:1824083. |
the influence of repeated s.c. administration of the cytostatic 5-[2-(n,n-dimethylamino)ethoxy]-7-oxo-7h-benzo(c)fluorene hydrochloride (benflurone, 25 mg/kg body weight daily) on the activities of aspartate and alanine aminotransferases (ast, alt) per g of tissue, and protein concentration in the liver of adult male rats was studied. |
1992-10-14 |
2023-08-11 |
rat |
| A Purroy, S García-Belenguer, J M Gonzalez, M Gascón, M Barberá. [Muscular lesions and enzymatic activities in fighting bulls]. Annales de recherches veterinaires. Annals of veterinary research. vol 23. issue 1. 1992-09-24. PMID:1510339. |
creatinine kinase (ck), lactate dehydrogenase (ldh) and aspartate transaminase (ast) serum enzyme activities were increased after the corrida or the tienta. |
1992-09-24 |
2023-08-11 |
Not clear |