| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Gómez, A Conde, J M Santana, A Jorrín, I M Serrano, R Medin. The diagnostic usefulness of AUDIT and AUDIT-C for detecting hazardous drinkers in the elderly. Aging & mental health. vol 10. issue 5. 2007-01-03. PMID:16938691. |
gamma-glutamyltransferase (ggt), mean corpuscular volume (mcv), aspartate aminotransferase (ast) and alanine aminotransferase (alt) values were also determined. |
2007-01-03 |
2023-08-12 |
human |
| Heba Hosny Mansour, Hafez Farouk Hafez, Nadia Mohamed Fahm. Silymarin modulates Cisplatin-induced oxidative stress and hepatotoxicity in rats. Journal of biochemistry and molecular biology. vol 39. issue 6. 2007-01-03. PMID:17129399. |
hepatotoxicity was determined by changes in serum alanine aminotransferase [alt] and aspartate aminotransferase [ast], nitric oxide [no] levels, albumin and calcium levels, and superoxide dismutase [sod], glutathione peroxidase [gshpx] activities, glutathione content, malondialdehyde [mda] and nitric oxide [no] levels in liver tissue of rats. |
2007-01-03 |
2023-08-12 |
rat |
| N Yadav, S Khandelwa. Effect of Picroliv on cadmium-induced hepatic and renal damage in the rat. Human & experimental toxicology. vol 25. issue 10. 2007-01-03. PMID:17165624. |
the hepatoprotective action of picroliv was evident by its ability to lower the cd-induced liver function parameters--the serum enzymes, such as alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transpeptidase (ggt) and lactate dehydrogenase (ldh). |
2007-01-03 |
2023-08-12 |
rat |
| Karelia Montane-Jaime, Shelley Moore, Samuel Shafe, Roma Joseph, Helene Crooks, Lucinda Carr, Cindy L Ehler. ADH1C*2 allele is associated with alcohol dependence and elevated liver enzymes in Trinidad and Tobago. Alcohol (Fayetteville, N.Y.). vol 39. issue 2. 2006-12-28. PMID:17134660. |
serum levels of alanine and aspartate aminotransferase (alt, ast), alkaline phosphatase (alp), lactate dehydrogenase (ldh), and gamma-glutamyltransferase (ggt) as well as presence of hiv, hepatitis b surface antigen, and anti-hepatitis c virus antibody were determined. |
2006-12-28 |
2023-08-12 |
Not clear |
| L J Dewes, J Z Sandrini, J M Monserrat, J S Yune. Biochemical and physiological responses after exposure to microcystins in the crab Chasmagnathus granulatus (Decapoda, Brachyura). Ecotoxicology and environmental safety. vol 65. issue 2. 2006-12-22. PMID:16137763. |
analyzed variables included oxygen consumption, lipid peroxidation (lpo), enzyme activities (glutathione s-transferases or gst; alanine aminotransferase or alt; aspartate aminotransferase or ast; and lactate dehydrogenase or ldh), glycogen, and microcystins content. |
2006-12-22 |
2023-08-12 |
Not clear |
| Luca Aldrighetti, Carlo Pulitanò, Marcella Arru, Renato Finazzi, Marco Catena, Laura Soldini, Laura Comotti, Gianfranco Ferl. Impact of preoperative steroids administration on ischemia-reperfusion injury and systemic responses in liver surgery: a prospective randomized study. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 12. issue 6. 2006-12-22. PMID:16710858. |
serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin, coagulation parameters, and inflammatory mediators, interleukin 6 and tumor necrosis factor alpha were compared between the 2 groups. |
2006-12-22 |
2023-08-12 |
Not clear |
| Denizar Alberto da Silva Melo, Vasyl Custódio Saciura, Jose Antonio Tesser Poloni, Carmem Silvana Araújo Oliveira, José Carlos Farias Alves Filho, Rossali Zingano Padilha, Carlos Luis Reichel, Emilio Jeckel Neto, Raquel Mattos Oliveira, Luiz Cláudio D'avila, Adriana Kessler, Jarbas Rodrigues de Oliveir. Evaluation of renal enzymuria and cellular excretion as an marker of acute nephrotoxicity due to an overdose of paracetamol in Wistar rats. Clinica chimica acta; international journal of clinical chemistry. vol 373. issue 1-2. 2006-12-22. PMID:16806140. |
the present study was conducted to determine whether the urinary levels of excreted enzymes, gamma-glutamyltransferase (ggt), alkaline phosphatase (alp), lactate dehydrogenase (ldh), aspartate (ast) and alanine aminotransferases (alt), can efficiently indicate, within 24 h, an acute nephrotoxicity due to an overdose of paracetamol (par). |
2006-12-22 |
2023-08-12 |
rat |
| R Binev, I Valchev, J Nikolo. Studies on some paraclinical indices on intoxication in horses from freshly cut Jimson weed (Datura stramonium)-contaminated maize intended for ensiling. Journal of the South African Veterinary Association. vol 77. issue 3. 2006-12-21. PMID:17137056. |
for a 7-day period the following parameters were monitored: haemoglobin content (hgb), red blood cell counts (rbc), white blood cell counts (wbc), haematocrit (hct), mean corpuscular volume (mcv), mean corpuscular haemoglobin (mch), mean corpuscular haemoglobin concentration (mchc), differential white cell counts (dwc), erythrocyte sedimentation rate (esr), protein fractions, aspartate aminotransferase (ast), lactate dehydrogenase (ldh), total bilirubin (tb), direct bilirubin (db), blood glucose (glu), total protein (tp), globulin (glob) and albumin (alb). |
2006-12-21 |
2023-08-12 |
Not clear |
| Martins Ekor, Ebenezer Olatunde Farombi, Godwin O Emerol. Modulation of gentamicin-induced renal dysfunction and injury by the phenolic extract of soybean (Glycine max). Fundamental & clinical pharmacology. vol 20. issue 3. 2006-12-18. PMID:16671961. |
the activities of membrane-bound glucose-6-phosphatase (g6pase) and 5(1)-nucleotidase (5(1)-ntd) enzymes as well as gamma-glutamyltransferase (gamma-gt) and aspartate aminotransferase (ast) (enzymes that are located in the proximal tubule) were decreased. |
2006-12-18 |
2023-08-12 |
rat |
| Hale Z Toklu, A Ozer Sehirli, Ayliz Velioğlu-Oğünç, Sule Cetinel, Göksel Sene. Acetaminophen-induced toxicity is prevented by beta-D-glucan treatment in mice. European journal of pharmacology. vol 543. issue 1-3. 2006-12-11. PMID:16822497. |
four hours after the acetaminophen injection, mice were decapitated and their blood was taken to determine serum aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh) and tumor necrosis factor-alpha (tnf-alpha) levels. |
2006-12-11 |
2023-08-12 |
mouse |
| Hyeung Sik Lee, Hyo Chan Ahn, Sae Kwang K. Hypolipemic effect of water extracts of Picrorrhiza rhizoma in PX-407 induced hyperlipemic ICR mouse model with hepatoprotective effects: a prevention study. Journal of ethnopharmacology. vol 105. issue 3. 2006-12-04. PMID:16406704. |
doses of 50, 100 and 200 mg/kg of pr extracts were given orally once a day for 12 weeks initiated with intraperitoneal injection of px-407 (0.5 g/kg), and changes in body weight and gains, liver weight, serum aspartate transferase (ast) and alanine transferase (alt) levels were monitored with serum low density lipoprotein (ldl), high density lipoprotein (hdl), triglyceride and total cholesterol levels. |
2006-12-04 |
2023-08-12 |
mouse |
| A James Hanje, Jennifer L Shamp, Fred B Thomas, Greg M Mei. Thalidomide-induced severe hepatotoxicity. Pharmacotherapy. vol 26. issue 7. 2006-12-04. PMID:16803426. |
by week 6 of therapy, she had developed acute increases in her aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels to more than 50 times the upper limit of normal. |
2006-12-04 |
2023-08-12 |
Not clear |
| Ming-Lung Yu, Shi-Ming Lin, Chuan-Mo Lee, Chia-Yen Dai, Wen-Yu Chang, Shinn-Cherng Chen, Li-Po Lee, Zu-Yau Lin, Ming-Yuh Hsieh, Liang-Yen Wang, Wan-Long Chuang, Yun-Fan Lia. A simple noninvasive index for predicting long-term outcome of chronic hepatitis C after interferon-based therapy. Hepatology (Baltimore, Md.). vol 44. issue 5. 2006-11-30. PMID:17058238. |
this study evaluated the predictive value of a simple noninvasive index, the aspartate aminotransferase (ast)-to-platelet ratio index assessed 6 months after end of treatment (apri-m6). |
2006-11-30 |
2023-08-12 |
Not clear |
| K Valentová, D Buckiová, V Kren, J Peknicová, J Ulrichová, V Simáne. The in vitro biological activity of Lepidium meyenii extracts. Cell biology and toxicology. vol 22. issue 2. 2006-11-29. PMID:16528448. |
the extracts did not exhibit cytotoxicity in hepatocyte primary cultures up to 10 mg/ml as measured by the mtt viability test, and lactate dehydrogenase (ldh) and aspartate aminotransferase (ast) leakage. |
2006-11-29 |
2023-08-12 |
human |
| Ying-Shan Jin, Min-Jae Lee, Woong Han, Seong-Il Heo, Soo In Sohn, Myeong-Hyeon Wan. Antioxidant effects and hepatoprotective activity of 2,5-dihydroxy-4,3'-di(beta-d-glucopyranosyloxy)-trans-stilbene from Morus bombycis Koidzumi roots on CCl4-induced liver damage. Free radical research. vol 40. issue 9. 2006-11-29. PMID:17015280. |
the increase in aspartate aminotransferase (ast) activities in serum associated with carbon tetrachloride (ccl4)-induced liver injury was inhibited by 2,5-dihydroxy-4,3'-di(beta-d-glucopyranosyloxy)-trans-stilbene and at a dose of 400 - 600 mg/kg samples had hepatoprotective activity comparable to the standard agent, silymarin. |
2006-11-29 |
2023-08-12 |
rat |
| Katsuhiro Isoda, Eri Arita, Midori Kojima, Masahiro Ikkaku, Fumi Tashiro, Eiji Yamato, Jun-ichi Miyazaki, Masaya Kawase, Masuo Kondoh, Kiyohito Yag. Protection against CCl4-induced injury in liver by adenovirally introduced thioredoxin gene. Biochemical and biophysical research communications. vol 350. issue 1. 2006-11-28. PMID:16996028. |
serum ammonia, aspartate aminotransferase (ast), and alanine aminotransferase (alt) levels were determined, and liver sections were stained with hematoxylin and eosin. |
2006-11-28 |
2023-08-12 |
mouse |
| D Lannoy, B Decaudin, A Grozieux de Laguérenne, F Barrier, J M Pignon, M Wetterwald, P Odo. Gemtuzumab ozogamicin-induced sinusoidal obstructive syndrome treated with defibrotide: a case report. Journal of clinical pharmacy and therapeutics. vol 31. issue 4. 2006-11-21. PMID:16882110. |
improved the hepatic abnormality within a few days (serum transaminases decreased from 312 to 103 iu/l for aspartate aminotransferase (ast) and from 141 to 80 iu/l for alanine aminotransferase (alt) within 3 days alp increased from 253 to 383 iu/l and gamma-gt from 238 to 417 iu/l 4 days after administration of df. |
2006-11-21 |
2023-08-12 |
Not clear |
| Mao-Hsiung Yen, Huei-Chen Ko, Fu-In Tang, Ru-Band Lu, Jau-Shyong Hon. Study of hepatotoxicity of naltrexone in the treatment of alcoholism. Alcohol (Fayetteville, N.Y.). vol 38. issue 2. 2006-11-14. PMID:16839858. |
after the 12-week treatment, levels of the hepatic enzymes alanine aminotransferase (alt) and aspartate aminotransferase (ast) did not show any elevation, except in one subject, and the results strongly support that ntx did not induce abnormalities in liver function tests or elevate the liver enzymes. |
2006-11-14 |
2023-08-12 |
human |
| H Tremlett, S Seemüller, Y Zhao, E M Yoshida, J D en M Oger, J Petka. Liver test abnormalities in multiple sclerosis: findings from placebo-treated patients. Neurology. vol 67. issue 7. 2006-11-08. PMID:17030771. |
the risk of an abnormal liver test in 813 patients with multiple sclerosis or clinically isolated syndrome enrolled in placebo arms of clinical trials was greater than expected for alanine aminotransferase (alt) (relative risk [rr] 3.7; 95% ci: 2.3 to 6.0) and aspartate aminotransferase (ast) (rr 2.2; 95% ci: 1.3 to 3.6), although not alkaline phosphatase (ap) or total bilirubin, at first presentation. |
2006-11-08 |
2023-08-12 |
Not clear |
| Ahmed M El-Gohary, Naglaa A Fawaz, Howayda M Hassoba, Abdelhamed Serwah, Mohamed Al. Soluble ICAM-1 in patients with chronic hepatitis C infection: a prognostic marker of disease activity. The Egyptian journal of immunology. vol 11. issue 2. 2006-11-07. PMID:16734123. |
positive correlations were detected between serum levels of sicam-1 and serum alanine aminotranseferase (alt) (p<0.001), aspartate aminotranseferase (ast) (p<0.001), prothrompin time (p<0.001), and alkaline phosphatase (p<0.001), while, a negative correlation with albumin was found (p<0.001). |
2006-11-07 |
2023-08-12 |
human |