| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tsai-Ching Hsu, Chih-Yang Huang, Szu-Yi Chiang, Wen-Xian Lai, Chang-Hai Tsai, Bor-Show Tzan. Transglutaminase inhibitor cystamine alleviates the abnormality in liver from NZB/W F1 mice. European journal of pharmacology. vol 579. issue 1-3. 2008-04-15. PMID:18031733. |
nephelometric analyses and immunoblots were conducted to detect aspartate aminotransferase (ast), alanine aminotransferase (alt), c-reactive protein (crp), p53, p21, gadd45, heat shock protein 70 (hsp70) and cyclooxygenase-2 (cox-2). |
2008-04-15 |
2023-08-12 |
mouse |
| Jun Wu, Jie Liu, Michael P Waalkes, Ming-Liang Cheng, Ling Li, Cheng-Xiu Li, Qing Yan. High dietary fat exacerbates arsenic-induced liver fibrosis in mice. Experimental biology and medicine (Maywood, N.J.). vol 233. issue 3. 2008-04-15. PMID:18296743. |
serum aspartate aminotransferase (ast), indicative of liver injury, was elevated in both arsenite and arsenate groups, and a high fat diet further increased these levels. |
2008-04-15 |
2023-08-12 |
mouse |
| Perumal Subramanian, Kadiyala Babu Dakshayani, Seithikurippu R Pandi-Perumal, Ilya Trakht, Daniel P Cardinal. 24-hour rhythms in oxidative stress during hepatocarcinogenesis in rats: effect of melatonin or alpha-ketoglutarate. Redox report : communications in free radical research. vol 13. issue 2. 2008-04-15. PMID:18339250. |
in blood collected at 6 time points during a 24-h period, serum activity of aspartate transaminase (ast) and alanine transaminase (alt) and the levels of alpha-fetoprotein (alpha-fp) were measured as markers of liver function. |
2008-04-15 |
2023-08-12 |
rat |
| Wen-Zheng Jiang, Yan Fan, Xia Liu, Ya-Li Zhang, Jie-Jun Wen, Wen-Li Hao, Min Qia. Therapeutic potential of dendritic cell-based immunization against HBV in transgenic mice. Antiviral research. vol 77. issue 1. 2008-04-08. PMID:17897731. |
the serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities were measured and no significant differences were observed between the different groups, which indicated that no hepatocellular injury occurred. |
2008-04-08 |
2023-08-12 |
mouse |
| Jun-Won Yun, Young-Kyung Kim, Byoung-Seok Lee, Chae-Wook Kim, Jin-Sook Hyun, Joo-Hyun Baik, Jung-Ju Kim, Bae-Hwan Ki. Effect of dietary epigallocatechin-3-gallate on cytochrome P450 2E1-dependent alcoholic liver damage: enhancement of fatty acid oxidation. Bioscience, biotechnology, and biochemistry. vol 71. issue 12. 2008-04-07. PMID:18071271. |
compared with an ethanol group, when egcg was present in the ethanol diet, the formation of a fatty liver was significantly reduced and the serum aspartate transaminase (ast) and alanine transaminase (alt) levels were much lower. |
2008-04-07 |
2023-08-12 |
Not clear |
| Lysandro Pinto Borges, Ricardo Brandão, Benhur Godoi, Cristina W Nogueira, Gilson Zen. Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats. Chemico-biological interactions. vol 171. issue 1. 2008-04-03. PMID:17950719. |
(phse)(2) administration ameliorated plasma malondialdehyde (mda) levels, aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ldh) and gamma-glutamyl transferase (ggt) activities increased by cdcl(2) exposure. |
2008-04-03 |
2023-08-12 |
human |
| Rajkapoor B, Venugopal Y, Anbu J, Harikrishnan N, Gobinath M, Ravichandran . Protective effect of Phyllanthus polyphyllus on acetaminophen induced hepatotoxicity in rats. Pakistan journal of pharmaceutical sciences. vol 21. issue 1. 2008-04-03. PMID:18166521. |
acetaminophen induced a significant rise in aspartate amino transferase (ast), alanine amino transferase (alt), alkaline phosphatase (alp), total bilirubin, gamma glutamate transpeptidase (ggtp), lipid peroxidase (lpo) with a reduction of total protein, superoxide dismutase (sod), catalase, glutathione peroxidase (gpx) and glutathione s-transferase (gst). |
2008-04-03 |
2023-08-12 |
rat |
| Hongli Xu, Tingting Guo, Yi-feng Guo, Jianp eng Zhang, Yang Li, Weihua Feng, Binghua Jia. Characterization and protection on acute liver injury of a polysaccharide MP-I from Mytilus coruscus. Glycobiology. vol 18. issue 1. 2008-03-31. PMID:17965434. |
pharmacological studies revealed that mp-i could decrease serum alanine aminotransferase (alt), serum aspartate aminotransferase (ast), and hepatic malondialdehyde aldehydes (mda) levels, increase the hepatic total superoxide dismutase (t-sod) activity, and improve hepatic damage in the ccl(4) induced liver injury in mice in a dose-dependent manner. |
2008-03-31 |
2023-08-12 |
mouse |
| O M E Abdel Salam, Fatma Hassan Oraby, Nabila S Hassa. Vinpocetine ameliorates acute hepatic damage caused by administration of carbon tetrachloride in rats. Acta biologica Hungarica. vol 58. issue 4. 2008-03-27. PMID:18277467. |
the results showed that vinpocetine administered to ccl4-treated rats decreased the elevated alanine aminotransferase (alt) by 49.3, 58.1 and 63.6%, aspartate aminotransferase (ast) by 10.5, 22.6 and 27.2% and alkaline phosphatase (alp) by 52.5, 59.6 and 64.9%, respectively, and in a dose-dependent manner. |
2008-03-27 |
2023-08-12 |
rat |
| Tae Hoon Lee, W Ray Kim, Joanne T Benson, Terry M Therneau, L Joseph Melto. Serum aminotransferase activity and mortality risk in a United States community. Hepatology (Baltimore, Md.). vol 47. issue 3. 2008-03-21. PMID:18302294. |
serum aminotransferase [such as aspartate aminotransferase (ast) and alanine aminotransferase (alt)] is commonly used as an indicator of liver disease. |
2008-03-21 |
2023-08-12 |
human |
| M Miyata, H Kasai, K Kawai, N Yamada, M Tokudome, H Ichikawa, C Goto, Y Tokudome, K Kuriki, H Hoshino, K Shibata, S Suzuki, M Kobayashi, H Goto, M Ikeda, T Otsuka, S Tokudom. Changes of urinary 8-hydroxydeoxyguanosine levels during a two-day ultramarathon race period in Japanese non-professional runners. International journal of sports medicine. vol 29. issue 1. 2008-03-20. PMID:17614024. |
we analyzed urine for 8-ohdg and blood for aspartate aminotransferase (ast), creatine phosphokinase (cpk) and myoglobin, and evaluated fluctuation in the values at three sampling time points. |
2008-03-20 |
2023-08-12 |
human |
| Refiye Yanardag, Ozlem Ozsoy-Sacan, Sadakat Ozdil, Sehnaz Bolken. Combined effects of vitamin C, vitamin E, and sodium selenate supplementation on absolute ethanol-induced injury in various organs of rats. International journal of toxicology. vol 26. issue 6. 2008-03-17. PMID:18066967. |
myeloperoxidase (mpo), aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), gamma-glutamyltransferase (ggt) were determined in liver tissue. |
2008-03-17 |
2023-08-12 |
rat |
| Rita P S Middelberg, Sarah E Medland, Nicholas G Martin, John B Whitfiel. A longitudinal genetic study of uric acid and liver enzymes in adolescent twins. Twin research and human genetics : the official journal of the International Society for Twin Studies. vol 10. issue 5. 2008-03-14. PMID:17903117. |
biochemical traits such as plasma alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma glutamyltransferase (ggt) and uric acid are associated with obesity, and with risk of cardiovascular disease, metabolic syndrome and diabetes. |
2008-03-14 |
2023-08-12 |
human |
| Nadana Saravanan, Namasivayam Nalin. Antioxidant effect of Hemidesmus indicus on ethanol-induced hepatotoxicity in rats. Journal of medicinal food. vol 10. issue 4. 2008-03-13. PMID:18158840. |
the liver marker enzymes, aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatae (alp), gamma-glutamyl transpeptidase (ggt), and lactate dehydrogenase (ldh), were elevated. |
2008-03-13 |
2023-08-12 |
rat |
| Matteo Monami, Gianluca Bardini, Caterina Lamanna, Laura Pala, Barbara Cresci, Paolo Francesconi, Eva Buiatti, Carlo M Rotella, Edoardo Mannucc. Liver enzymes and risk of diabetes and cardiovascular disease: results of the Firenze Bagno a Ripoli (FIBAR) study. Metabolism: clinical and experimental. vol 57. issue 3. 2008-03-11. PMID:18249212. |
the aim of the study was to assess gamma-glutamyl transpeptidase (gamma-gt), alanine aminotransferase, and aspartate aminotransferase (ast) in the prediction of diabetes and cardiovascular disease (cvd) in subjects free from hepatic diseases other than nonalcoholic fatty liver disease. |
2008-03-11 |
2023-08-12 |
human |
| M Modi, S J S Flor. Combined administration of iron and monoisoamyl-DMSA in the treatment of chronic arsenic intoxication in mice. Cell biology and toxicology. vol 23. issue 6. 2008-03-06. PMID:17453351. |
liver aspartate and alanine transaminases (ast and alt) activities also decreased significantly on arsenic exposure. |
2008-03-06 |
2023-08-12 |
mouse |
| I Ozdemir, Z Selamoglu, B Ates, Y Gok, I Yilma. Modulation of DMBA-induced biochemical changes by organoselenium compounds in blood of rats. Indian journal of biochemistry & biophysics. vol 44. issue 4. 2008-03-05. PMID:17970285. |
sei and seii caused a significant (p<0.05) decrease in urea, uric acid and creatinine levels and alanine aminotransferase (alt); aspartate aminotransferase; (ast) and lactate dehydrogenase (ldh) activities and significantly increased the levels of total protein and albumin (p<0.05). |
2008-03-05 |
2023-08-12 |
human |
| J Berenguer, J M Bellón, P Miralles, E Alvarez, M Sánchez-Conde, J Cosín, J C López, F Alvarez, P Catalán, S Resin. Identification of liver fibrosis in HIV/HCV-coinfected patients using a simple predictive model based on routine laboratory data. Journal of viral hepatitis. vol 14. issue 12. 2008-03-04. PMID:18070289. |
we developed the hospital gregorio marañón (hgm)-1 index, based on platelet count, aspartate aminotransferase (ast) and glucose, to predict f > or = 2 and the hgm-2 index, based on platelet count, international normalized ratio, alkaline phosphatase and ast to predict f > or = 3. |
2008-03-04 |
2023-08-12 |
human |
| H Erhan Guven, Suleyman Ora. Liver enzyme alterations after laparoscopic cholecystectomy. Journal of gastrointestinal and liver diseases : JGLD. vol 16. issue 4. 2008-02-28. PMID:18193120. |
we aimed to investigate the alterations in serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl-transferase (ggt), alkaline phosphatase (alp) and lactate dehydrogenase (ldh) in patients who had undergone laparoscopic cholecystectomy (lc) and compare these changes with those occurring after open cholecystectomy (oc). |
2008-02-28 |
2023-08-12 |
Not clear |
| Hasan Kaya, Ahmet Koc, Sadik Sogut, Mehmet Duru, H Ramazan Yilmaz, Efkan Uz, Ramazan Durgu. The protective effect of N-acetylcysteine against cyclosporine A-induced hepatotoxicity in rats. Journal of applied toxicology : JAT. vol 28. issue 1. 2008-02-26. PMID:17461432. |
the aim of this study was to investigate the effects of n-acetylcysteine (nac) treatment on csa-induced hepatic damage by both analysing superoxide dismutase (sod), glutathione peroxidase (gsh-px), aspartate aminotransferase (ast) and alanine transaminase (alt) activities with malondialdehyde (mda) and nitric oxide (no) levels, and using an histological approach. |
2008-02-26 |
2023-08-12 |
rat |