| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Janet Olayemi Olugbodi, Bashir Lawal, Godiya Bako, Amos Sunday Onikanni, Sulama M Abolenin, Soliman S Mohammud, Farid S Ataya, Gaber El-Saber Batih. Effect of sub-dermal exposure of silver nanoparticles on hepatic, renal and cardiac functions accompanying oxidative damage in male Wistar rats. Scientific reports. vol 13. issue 1. 2023-06-29. PMID:37386048. |
our results revealed that the subdermal administration of agnps induced significant increased (p < 0.05) activities of aspartate aminotransferase (ast), alanine transferase (alt), alkaline phosphatase (alp), urea, creatinine, and malondialdehyde (mda) while decreasing the levels of glutathione (gsh), catalase (cat), superoxide dismutase (sod), and total thiol groups in the rat tissues. |
2023-06-29 |
2023-08-14 |
human |
| Franccesco P Boeno, Jay Patel, Ryan N Montalvo, Stephanie S Lapierre-Nguyen, Claire M Schreiber, Ashley J Smude. Effects of Exercise Preconditioning on Doxorubicin-Induced Liver and Kidney Toxicity in Male and Female Rats. International journal of molecular sciences. vol 24. issue 12. 2023-06-28. PMID:37373368. |
while there is currently no standard of care to treat dox hepatic- and nephrotoxicity, endurance exercise preconditioning may be an effective intervention to prevent elevations in liver alanine transaminase (alt) and aspartate aminotransferase (ast) and to improve kidney creatinine clearance. |
2023-06-28 |
2023-08-14 |
rat |
| Raja Chinnappan, Tanveer Ahmad Mir, Sulaiman Alsalameh, Tariq Makhzoum, Salma Adeeb, Khaled Al-Kattan, Ahmed Yaqinuddi. Aptasensors Are Conjectured as Promising ALT and AST Diagnostic Tools for the Early Diagnosis of Acute Liver Injury. Life (Basel, Switzerland). vol 13. issue 6. 2023-06-28. PMID:37374056. |
abnormal levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in human serum are the most sensitive indicator of hepatocellular damage. |
2023-06-28 |
2023-08-14 |
human |
| Arduino A Mangoni, Angelo Zinell. An Updated Systematic Review and Meta-Analysis of the Association between the De Ritis Ratio and Disease Severity and Mortality in Patients with COVID-19. Life (Basel, Switzerland). vol 13. issue 6. 2023-06-28. PMID:37374107. |
patients with coronavirus disease 2019 (covid-19) often have elevations in markers of liver injury, particularly serum aspartate transaminase (ast) and alanine transaminase (alt). |
2023-06-28 |
2023-08-14 |
Not clear |
| S Rahimnejad, E Leclercq, O Malinovskyi, T Pěnka, J Kolářová, T Polica. Effects of yeast hydrolysate supplementation in low-fish meal diets for pikeperch. Animal : an international journal of animal bioscience. vol 17. issue 7. 2023-06-28. PMID:37379608. |
the highest alanine aminotransferase, aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) activities were detected in the sm60 group, and yh addition significantly decreased the ast and ldh activities. |
2023-06-28 |
2023-08-14 |
Not clear |
| Adem Kara, Seckin Ozkanla. Blockade of P2X7 receptor-mediated purinergic signaling with A438079 protects against LPS-induced liver injury in rats. Journal of biochemical and molecular toxicology. 2023-06-27. PMID:37365769. |
in the biochemical analysis, serum aspartate transaminase (ast) and alanine transaminase (alt) concentrations, the tissue glutathione (gsh) level, and superoxide dismutase (sod) activity dramatically decreased and malondialdehyde (mda) level increased in the lps and lps + dmso groups compared to the lps + a438079 group. |
2023-06-27 |
2023-08-14 |
rat |
| Taseer Ahmad, Taous Khan, Annet Kirabo, Abdul Jabbar Sha. Antioxidant Flavonoid Diosmetin Is Cardioprotective in a Rat Model of Myocardial Infarction Induced by Beta 1-Adrenergic Receptors Activation. Current issues in molecular biology. vol 45. issue 6. 2023-06-27. PMID:37367046. |
to test this hypothesis, we evaluated the cardioprotective potential of diosmetin on isoproterenol-induced mi in rats by performing lead ii electrocardiography (ecg), cardiac biomarkers including troponin i (ctni) and creatinine phosphokinase (cpk), ck-myocardial band, (ck-mb), lactate dehydrogenase (ldh), alanine aminotransferase (alt), and aspartate aminotranferase (ast) by using biolyzer 100, as well as histopathological analysis. |
2023-06-27 |
2023-08-14 |
rat |
| Jiangxue Han, Shunwang Li, Weizhi Wang, Xinhai Jiang, Chao Liu, Lijuan Lei, Yining Li, Ren Sheng, Yuyan Zhang, Yexiang Wu, Jing Zhang, Yuhao Zhang, Yanni Xu, Shuyi S. SIRT1 Activator E1231 Alleviates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism. Current issues in molecular biology. vol 45. issue 6. 2023-06-27. PMID:37367070. |
liver-related plasma biochemistry parameter tests, oil red o staining, and hematoxylin-eosin staining results showed that e1231 treatment ameliorated plasma dyslipidemia, plasma marker levels of liver damage (alanine aminotransferase (alt) and aspartate aminotransferase (ast)), liver total cholesterol (tc) and triglycerides (tg) contents, and obviously decreased hepatic steatosis score and nafld activity score (nas) in the nafld mouse model. |
2023-06-27 |
2023-08-14 |
mouse |
| Ayaka Kasai, Mitsuo Motobayashi, Makoto Nishioka, Tetsuhiro Fukuyama, Yuji Inab. A serial analysis of serum aspartate aminotransferase levels in patients with acute encephalopathy with biphasic seizures and late reduced diffusion and prolonged febrile seizure. Brain & development. 2023-06-25. PMID:37357027. |
based on our clinical experience, we hypothesized that serial examinations of blood levels of aspartate aminotransferase (ast) in children with febrile convulsive status epilepticus (fcse) revealed higher levels in patients with aesd in the 1st seizure phase than in those with prolonged febrile seizures (pfs). |
2023-06-25 |
2023-08-14 |
Not clear |
| Shengpeng Zhang, Peng Zhu, Jianan Yuan, Kunming Cheng, Qixiang Xu, Wei Chen, Zui Pan, Yongqiu Zhen. Non-alcoholic fatty liver disease combined with rheumatoid arthritis exacerbates liver fibrosis by stimulating co-localization of PTRF and TLR4 in rats. Frontiers in pharmacology. vol 14. 2023-06-22. PMID:37346294. |
the development of nafld was further evaluated by measuring serum concentrations of triglyceride (tg), total cholesterol (t-cho), alanine aminotransferase (alt), aspartate aminotransferase (ast), and lipopolysaccharide (lps). |
2023-06-22 |
2023-08-14 |
rat |
| Siwen Li, Jiaqi Xie, Yiang Bai, Zhihao Jiang, Keman Li, Chunling W. Synthetic phenolic antioxidants evoked hepatoxicity in grass carp (Ctenopharyngodon idella) through modulating the ROS-PI3K/mTOR/AKT pathway: Apoptosis-autophagy crosstalk. Fish & shellfish immunology. 2023-06-22. PMID:37348686. |
we observed that bha and bht exposure significantly increased the levels of serum aminotransferase (alt) and aspartate aminotransferase (ast) in grass carp, accompanied by mild inflammatory cell infiltration and irregularity in the shape of hepatocytes. |
2023-06-22 |
2023-08-14 |
cat |
| Muxue Gong, Li Dai, Zhuobei Xie, Dengxiao Hong, Ning Li, Xiaoyun Fan, Changhao Xi. Serological and clinical associations of autoantibodies in Chinese patients with new-onset systemic lupus erythematosus. Scientific reports. vol 13. issue 1. 2023-06-21. PMID:37344560. |
patients with anti-ssb (43.95 ± 73.12 vs. 40.92 ± 75.75, p = 0.004; 63.93 ± 103.56 vs. 55.06 ± 120.84, p = 0.008 respectively) antibodies had higher levels of alanine aminotransferase (alt) and aspartate transaminase (ast), whereas those with anti-p antibody (28.90 ± 25.70 vs. 50.08 ± 93.00, p = 0.014; 38.51 ± 48.19 vs. 69.95 ± 142.67, p = 0.047, respectively) had lower levels of them. |
2023-06-21 |
2023-08-14 |
Not clear |
| Wenmiao He, Aihua Gu, Dayong Wan. Four-week repeated exposure to tire-derived 6-PPD quinone causes multiple organ injury in male BALB/c mice. The Science of the total environment. 2023-06-19. PMID:37336398. |
biochemical parameters of liver (alanine aminotransferase (alt), aspartate aminotransferase (ast), and alkaline phosphatase (alp)) and kidney (urea and creatinine) were all significantly upregulated by repeated injection with 0.4 and 4 mg/kg 6-ppdq. |
2023-06-19 |
2023-08-14 |
mouse |
| Ashraf B Abdel-Naim, Emad H M Hassanein, Lenah S Binmahfouz, Amina M Bagher, Rawan H Hareeri, Mardi M Algandaby, Yousef A J Fadladdin, Lotfi Aleya, Mohamed M Abdel-Dai. Lycopene attenuates chlorpyrifos-induced hepatotoxicity in rats via activation of Nrf2/HO-1 axis. Ecotoxicology and environmental safety. vol 262. 2023-06-17. PMID:37329850. |
lcp offered protection as evidenced by inhibiting the rise in serum activities of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), and lactate dehydrogenase (ldh) induced by cpf. |
2023-06-17 |
2023-08-14 |
rat |
| Ali Ardekani, Reza Tabrizi, Elham Maleki, Kamran Bagheri Lankarani, Seyed Taghi Heydari, Mehdi Moradinazar, Maryam Akbar. Effects of coenzyme Q10 supplementation on lipid profiles and liver enzymes of nonalcoholic fatty liver disease (NAFLD) patients: A systematic review and meta-analysis of randomized controlled trials. Food science & nutrition. vol 11. issue 6. 2023-06-16. PMID:37324909. |
the analysis of the six included studies indicated an overall non-significant decrease in the lipid profiles (total cholesterol (tc), low-density lipoprotein cholesterol (ldl), high-density lipoprotein cholesterol (hdl), and triglyceride (tg)), and liver enzymes (aspartate transaminase (ast), alanine transaminase (alt), and gamma-glutamyltransferase (ggt)) of nafld patients who received coq10. |
2023-06-16 |
2023-08-14 |
Not clear |
| Mahmoud M Abo Ghanima, Mohamed E Abd El-Hack, Aljohara M Al-Otaibi, Samia Nasr, Najlaa H Almohmadi, Ayman E Taha, Mariusz Jaremko, Nagwa I El-Kasraw. Growth performance, liver and kidney functions, blood hormonal profile, and economic efficiency of broilers fed different levels of threonine supplementation during feed restriction. Poultry science. vol 102. issue 8. 2023-06-15. PMID:37321031. |
also, a significant increase in alanine aminotransferase (alt), aspartate aminotransferase (ast), and urea levels was observed in feed-restricted birds supplemented with 120 and 130% levels of threonine. |
2023-06-15 |
2023-08-14 |
Not clear |
| Masoud Khosravipour, Masoud Ghanbari Kakavandi, Faramarz Gharagozlou, Farshad Nadri, Akbar Barzegar, Khosro Emami, Hossein Valadi Atha. Independent, modified, and interacting effects of long-term noise, extremely low-frequency electromagnetic fields, and shift work exposures on liver enzymes. Environmental pollution (Barking, Essex : 1987). 2023-06-15. PMID:37321317. |
the fasting blood samples were taken to determine liver enzymes (ast, aspartate transaminase; alt, alanine transaminase). |
2023-06-15 |
2023-08-14 |
human |
| R Ahmed Mohammed, Q J Fadhee. Hepatoprotective Effect of Vitamin B12 in Acetaminophen Induce Hepatotoxicity in Male Rats. Archives of Razi Institute. vol 78. issue 1. 2023-06-14. PMID:37312722. |
plasma levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), glutathione (gsh), total antioxidant capacity (tac), caspase3, malondialdehyde (mda), interleukin-6 (il-6), and tumor necrosis factor-alpha (tnf-) were measured in the cardiac blood samples. |
2023-06-14 |
2023-08-14 |
human |
| Sipra Nayak, Samarendra Das, Rajesh Kumar, Ipsita Iswari Das, Aman Kumar Mohanty, Lakshman Sahoo, Gokul Krsihnan, Jitendra Kumar Sundara. Biochemical and histopathological alterations in freshwater fish, Labeo rohita (Hamilton, 1822) upon chronic exposure to a commonly used hopper insecticide, triflumezopyrim. Chemosphere. 2023-06-14. PMID:37315855. |
the liver, kidney, gills, muscle, and brain tissues of the fish were examined for physiological parameters and biochemical parameters such as catalase (cat), superoxide dismutase (sod), lactate dehydrogenase (ldh), malate dehydrogenase (mdh), alanine aminotransaminase (alt), aspartate aminotransaminase (ast), acetylcholinessterase (ache), and hexokinase. |
2023-06-14 |
2023-08-14 |
cat |
| Hussein G Sawie, Yasser A Khadrawy, Mayada M El-Gizawy, Hagar H Mourad, Enayat A Omara, Eman N Hosn. Effect of alpha-lipoic acid and caffeine-loaded chitosan nanoparticles on obesity and its complications in liver and kidney in rats. Naunyn-Schmiedeberg's archives of pharmacology. 2023-06-12. PMID:37306714. |
at the end of the experiment, the activities of aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp) and the levels of urea, creatinine, interleukin-1β (il-1β), and tumor necrosis factor-α (tnf-α) were determined in the sera of animals. |
2023-06-12 |
2023-08-14 |
rat |