| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fen Huang, Xiuguo Hua, Shixing Yang, Congli Yuan, Wen Zhan. Effective inhibition of hepatitis E virus replication in A549 cells and piglets by RNA interference (RNAi) targeting RNA-dependent RNA polymerase. Antiviral research. vol 83. issue 3. 2009-10-09. PMID:19576249. |
in piglets treated with a shrna-rdrp-1 expression plasmid prior to hev inoculation, hev antigens were significantly reduced in the liver, spleen, and kidneys, and the activities of alanine aminotransferase (alt), aspartate aminotransferase (ast) and total bilirubin (tbil) were clearly decreased. |
2009-10-09 |
2023-08-12 |
Not clear |
| Ayano Itoh, Katsuhiro Isoda, Masuo Kondoh, Masaya Kawase, Masakazu Kobayashi, Makoto Tamesada, Kiyohito Yag. Hepatoprotective effect of syringic acid and vanillic acid on concanavalin a-induced liver injury. Biological & pharmaceutical bulletin. vol 32. issue 7. 2009-10-08. PMID:19571388. |
cona injection into the tail vein caused a great increase in the serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels. |
2009-10-08 |
2023-08-12 |
mouse |
| Amit Kumar Mehta, Naveen Arora, Shailendra Nath Gaur, Bhanu Pratap Sing. Acute toxicity assessment of choline by inhalation, intraperitoneal and oral routes in Balb/c mice. Regulatory toxicology and pharmacology : RTP. vol 54. issue 3. 2009-10-07. PMID:19460409. |
liver function test was performed by assaying different enzyme systems in serum such as, urea, blood urea nitrogen (bun), creatinine, alanine aminotransferase (alt), and aspartate aminotransferase (ast). |
2009-10-07 |
2023-08-12 |
mouse |
| M Mohri, R Narenji Sani, R Masood. Plasma biochemistry of ostrich (Struthio camelus): effects of anticoagulants and comparison with serum. Tropical animal health and production. vol 41. issue 6. 2009-10-05. PMID:19011988. |
the concentrations of glucose, cholesterol, uric acid, creatinine, total protein, albumin, calcium, inorganic phosphorus, and magnesium and the activity of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), and gamma glutamyl transferase (ggt) were measured. |
2009-10-05 |
2023-08-12 |
Not clear |
| Uta Drebber, Juliane J M Mueller, Ellen Klein, Hans U Kasper, Falko Schulze, Katharina Schardt, Maria Quasdorff, Sigrid Schulte, Margarete Odenthal, Hans P Diene. Liver biopsy in primary biliary cirrhosis: clinicopathological data and stage. Pathology international. vol 59. issue 8. 2009-10-01. PMID:19627538. |
combining the data, a pbc group, consisting of an anti-mitochondrial antibody (ama)-positive and -negative subgroup, and an overlap group were defined, with a female preponderance of >90% and higher activity of aspartate aminotransferase (ast) in the overlap group. |
2009-10-01 |
2023-08-12 |
Not clear |
| M G Martin, G L Uy, E Procknow, K Stockerl-Goldstein, A Cashen, P Westervelt, C N Abboud, K Augustin, J Luo, J F DiPersio, R Vi. Allo-SCT conditioning for myelodysplastic syndrome and acute myeloid leukemia with clofarabine, cytarabine and ATG. Bone marrow transplantation. vol 44. issue 1. 2009-09-29. PMID:19139740. |
toxicities included hand-foot syndrome (57% grade 2), elevated alanine aminotransferase (alt) (57% grade 3), elevated aspartate aminotransferase (ast) (86% grade 3) and hyperbilirubinemia (29% grade 3-5). |
2009-09-29 |
2023-08-12 |
Not clear |
| Khaled Hamden, Serge Carreau, Kamel Jamoussi, Slaheddine Miladi, Samiha Lajmi, Dorra Aloulou, Fatma Ayadi, Abdelfattah Elfek. 1Alpha,25 dihydroxyvitamin D3: therapeutic and preventive effects against oxidative stress, hepatic, pancreatic and renal injury in alloxan-induced diabetes in rats. Journal of nutritional science and vitaminology. vol 55. issue 3. 2009-09-24. PMID:19602829. |
it also reduced lipid peroxidation and the indices of toxicity in liver and kidneys by significantly decreasing alkaline phosphatases (pal), aspartate and lactate transaminase (ast and alt) activities, total and direct bilirubin, triglycerides (tg), cholesterol, creatinine, urea and iron levels in diabetic rats. |
2009-09-24 |
2023-08-12 |
rat |
| Egemen Dere, Ferda Ar. Effect of Benzene on liver functions in rats (Rattus norvegicus). Environmental monitoring and assessment. vol 154. issue 1-4. 2009-09-22. PMID:18566902. |
changes in lactate dehydrogenase (ldh), alkaline phosphatase (alp), alanine amino transferase (alt), aspartate amino transferase (ast) activities in serum of rats were investigated at 2, 4, 8, 16, 32, and 64 h following injection. |
2009-09-22 |
2023-08-12 |
rat |
| Ismail Cetin Ozturk, Feral Ozturk, Mehmet Gul, Burhan Ates, Asli Ceti. Protective effects of ascorbic acid on hepatotoxicity and oxidative stress caused by carbon tetrachloride in the liver of Wistar rats. Cell biochemistry and function. vol 27. issue 5. 2009-09-21. PMID:19548269. |
mda, total glutathione (t.gsh) levels and superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gsh-px) activities were measured in the liver of all groups of rats and also serum alanine amino transferase (alt) and aspartate amino transferase (ast) activities were detected to determine liver functions in all groups of rats. |
2009-09-21 |
2023-08-12 |
rat |
| Xiao-dong Peng, Li-li Dai, Chang-quan Huang, Chun-mei He, Bing Yang, Li-juan Che. Relationship between anti-fibrotic effect of Panax notoginseng saponins and serum cytokines in rat hepatic fibrosis. Biochemical and biophysical research communications. vol 388. issue 1. 2009-09-21. PMID:19632202. |
liver index, serum alanine amino transferase (alt), aspartate amino transferase (ast), transforming growth factor-beta1 (tgf-beta1), tumour necrosis factor-alpha (tnf-alpha), interleukin-6 (il-6) and interleukin-10 (il-10) were measured, respectively. |
2009-09-21 |
2023-08-12 |
rat |
| Guiying Li, Chang Han, Lihong Xu, Kyu Lim, Kumiko Isse, Tong W. Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor. Hepatology (Baltimore, Md.). vol 50. issue 3. 2009-09-18. PMID:19585617. |
the cox-2 tg mice showed resistance to fas-induced liver injury in comparison with the wild-type mice; this was reflected by the lower alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, less liver damage, and less hepatocyte apoptosis (p < 0.01). |
2009-09-18 |
2023-08-12 |
mouse |
| Guan-min Zhang, Liang Li, Wen-qian Chen, Shan-shan Bi, Xiao Liu, Xiang-lin Zhang, Wei L. [Population pharmacokinetics of tacrolimus in Chinese renal transplant patients]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 43. issue 7. 2009-09-17. PMID:18819472. |
the final population model related clearance with pod (post operative days), hct (haematocrit), ast (aspartate aminotransferase) and coadministration of nicardipine and diltiazem. |
2009-09-17 |
2023-08-12 |
Not clear |
| Jinlong Chen, Mengmeng Ma, Yanwei Lu, Lisheng Wang, Chutse Wu, Haifeng Dua. Rhaponticin from rhubarb rhizomes alleviates liver steatosis and improves blood glucose and lipid profiles in KK/Ay diabetic mice. Planta medica. vol 75. issue 5. 2009-09-15. PMID:19235684. |
serum enzymatic activities of lactate dehydrogenase (ldh), creatine kinase (ck), aspartate aminotransferase (ast), and alanine aminotransferase (alt) in the rhaponticin-treated group significantly decreased in comparison to the untreated model group. |
2009-09-15 |
2023-08-12 |
mouse |
| Gamal A El-Sherbiny, Ashraf Taye, Ihab T Abdel-Rahee. Role of ursodeoxycholic acid in prevention of hepatotoxicity caused by amoxicillin-clavulanic acid in rats. Annals of hepatology. vol 8. issue 2. 2009-09-08. PMID:19502657. |
our results show that pretreatment with udca reduced the liver parameters that were enhanced by single or combined administration of amox and/or clav such as serum activities of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp) and serum bilirubin levels. |
2009-09-08 |
2023-08-12 |
rat |
| Rajesh Krithika, Ramtej J Verm. Mitigation of carbon tetrachloride-induced damage by Phyllanthus amarus in liver of mice. Acta poloniae pharmaceutica. vol 66. issue 4. 2009-09-08. PMID:19702178. |
carbon tetrachloride administration caused a significant increase in liver and serum alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp) and acid phosphatase (acp), while total protein content significantly decreased as compared to vehicle control. |
2009-09-08 |
2023-08-12 |
mouse |
| Ashwag A Albukhari, Hana M Gashlan, Hesham A El-Beshbishy, Ayman A Nagy, Ashraf B Abdel-Nai. Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 47. issue 7. 2009-08-28. PMID:19394397. |
tam (45 mg/kg/day, i.p., for 10 consecutive days) resulted in an elevation of serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp), depletion of liver reduced glutathione (gsh) and accumulation of oxidized glutathione (gssg) and lipid peroxidation (lpo). |
2009-08-28 |
2023-08-12 |
rat |
| Xian-Jun Qu, Xue Xia, Yuan-Shu Wang, Mei-Juan Song, Li-Li Liu, Yan-Ying Xie, Yan-Na Cheng, Xiang-Juan Liu, Lu-Lu Qiu, Lan Xiang, Jian-Jun Gao, Xiao-Fan Zhang, Shu-Xiang Cu. Protective effects of Salvia plebeia compound homoplantaginin on hepatocyte injury. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 47. issue 7. 2009-08-28. PMID:19406199. |
homoplantaginin (25-100mg/kg) significantly reduced the increase in serum alanine aminotranseferase (alt) and aspartate aminotransferase (ast), decreased the levels of tumor necrosis factor-alpha (tnf-alpha) and interleukin-1 (il-1). |
2009-08-28 |
2023-08-12 |
mouse |
| Zdeno Pirnik, Jana Bundzikova, Tomas Francisty, Elena Cibulova, Lubica Lackovicova, Boris Mravec, Alexander Kis. Effect of liver ischemia-reperfusion injury on the activity of neurons in the rat brain. Cellular and molecular neurobiology. vol 29. issue 6-7. 2009-08-19. PMID:19283466. |
ninety minutes, 5 h, and 24 h after liver reperfusion, alanine aminotransferase (alt) and aspartate aminotransferase (ast), interleukin 1alpha (il-1alpha), and tumor necrosis factor alpha (tnfalpha) serum levels were analyzed and fos-immunolabeled cells counted in subfornical organ (sfo), suprachiasmatic (sch), paraventricular (pvn), supraoptic (son), arcuate (arc), and ventromedial (vmn) hypothalamic nuclei, locus coeruleus (lc), nucleus of the solitary tract (nts), and a1/c1 catecholaminergic cell groups. |
2009-08-19 |
2023-08-12 |
rat |
| Brahma N Singh, Braj R Singh, B K Sarma, H B Sing. Potential chemoprevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by polyphenolics from Acacia nilotica bark. Chemico-biological interactions. vol 181. issue 1. 2009-08-18. PMID:19446540. |
the levels of liver injury and liver cancer markers such as alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), gamma-glutamyl transferase (gamma-gt), total bilirubin level (tbl), alpha-feto protein (afp) and carcinoembryonic antigen (cea) were substantially increased following ndea treatment. |
2009-08-18 |
2023-08-12 |
rat |
| Daniel Lindberg, Kathi Makoroff, Nancy Harper, Antoinette Laskey, Kirsten Bechtel, Katherine Deye, Robert Shapir. Utility of hepatic transaminases to recognize abuse in children. Pediatrics. vol 124. issue 2. 2009-08-13. PMID:19620197. |
although experts recommend routine screening of hepatic transaminases (aspartate aminotransferase [ast] and alanine aminotransferase [alt]) in cases of potential child physical abuse, this practice is highly variable. |
2009-08-13 |
2023-08-12 |
Not clear |