| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fenggang Zhou, Ou Lv, Yongri Zheng, Jianjiao Wang, Peng Hu, Zhenyu Wang, Lizhuang Yan. Inhibitory effect of Pulsatilla chinensis polysaccharides on glioma. International journal of biological macromolecules. vol 50. issue 5. 2012-09-24. PMID:22342738. |
in addition, pcps administration to tumor bearing mice could relieve the liver and kidney damage with decreased levels of aspartate aminotransferase (ast), alanine aminotransferase (alt) and urea, and enhance superoxide dismutase (sod) and catalase (cat) enzyme activities with lower mda levels in the plasma of tumor bearing mice. |
2012-09-24 |
2023-08-12 |
mouse |
| Junming Wang, Yueyue Zhang, Yasu Zhang, Ying Cui, Ju Liu, Binfeng Zhan. Protective effect of Lysimachia christinae against acute alcohol-induced liver injury in mice. Bioscience trends. vol 6. issue 2. 2012-09-21. PMID:22621991. |
the results showed that alcohol-induced elevated serum alanine transferase (alt) and aspartate transaminase (ast) activities were significantly reduced by et (200, 400 mg/kg), quercetin (4, 8 mg/kg) and bifendate (150 mg/kg), respectively. |
2012-09-21 |
2023-08-12 |
mouse |
| Yavuz Silig, Oge Cetinkaya, L Omur Demireze. Effects of Rumex patientia L. extract on some drug-metabolizing enzymes in rat liver. Indian journal of biochemistry & biophysics. vol 41. issue 1. 2012-09-18. PMID:22896908. |
the effect of aqueous extract from the roots of rumex patientia l. (polygonaceae) (d-1), a traditional turkish medicine used as a laxative and cholagogue, on drug-metabolizing enzymes, such as cytochrome p4502e1, nadph cytochrome c reductase, nadh cytochrome b5 reductase and glutathione-s-transferase (gst); and serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) were studied in male wistar albino rat liver. |
2012-09-18 |
2023-08-12 |
rat |
| Olga Krystofova, Violetta Shestivska, Michaela Galiova, Karel Novotny, Jozef Kaiser, Josef Zehnalek, Petr Babula, Radka Opatrilova, Vojtech Adam, Rene Kize. Sunflower Plants as Bioindicators of Environmental Pollution with Lead (II) Ions. Sensors (Basel, Switzerland). vol 9. issue 7. 2012-09-10. PMID:22346686. |
we also focused our attention on the activity of alanine transaminase (alt), aspartate transaminase (ast) and urease. |
2012-09-10 |
2023-08-12 |
Not clear |
| Susan M Williams, Lisa Holthaus, Heather Wilson Barron, Stephen J Divers, Michael McBride, Frederic Almy, Sharon Bush, Kenneth S Latime. Improved clinicopathologic assessments of acute liver damage due to trauma in Indian ring-necked parakeets (Psittacula krameri manillensis). Journal of avian medicine and surgery. vol 26. issue 2. 2012-09-06. PMID:22872978. |
increased activities of certain biochemical enzymes (alanine aminotransferase [alt], aspartate aminotransferase [ast], lactate dehydrogenase [ldh], alkaline phosphatase [alp]) have been associated with blunt liver injury in many species. |
2012-09-06 |
2023-08-12 |
Not clear |
| Eun Jeong Choi, Taehee Kim, Gun-Hee Ki. Quercetin acts as an antioxidant and downregulates CYP1A1 and CYP1B1 against DMBA-induced oxidative stress in mice. Oncology reports. vol 28. issue 1. 2012-09-04. PMID:22469840. |
quercetin showed side effects such as increased aspartate aminotransferase (ast) and alanine aminotransferase (alt) in dmba-untreated mice. |
2012-09-04 |
2023-08-12 |
mouse |
| Peethambaran Arun, Samuel Oguntayo, Yonas Alamneh, Cary Honnold, Ying Wang, Manojkumar Valiyaveettil, Joseph B Long, Madhusoodana P Nambia. Rapid release of tissue enzymes into blood after blast exposure: potential use as biological dosimeters. PloS one. vol 7. issue 4. 2012-09-04. PMID:22493674. |
we evaluated the activity of plasma enzymes including aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh) and creatine kinase (ck) at different time points after blast exposure using a mouse model of single and repeated blast exposures to assess the severity of injury. |
2012-09-04 |
2023-08-12 |
mouse |
| Leelavinothan Pari, Kalist Shagirth. Hesperetin protects against oxidative stress related hepatic dysfunction by cadmium in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 64. issue 5. 2012-08-31. PMID:21134734. |
administration of cd (3 mg/kg body weight/day) subcutaneously for 21 days, the levels of hepatic markers such as aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ldh), gamma glutamyl transferase (ggt) and bilirubin were significantly increased in serum. |
2012-08-31 |
2023-08-12 |
rat |
| Michael T Tseng, Xiaoqin Lu, Xiaoxian Duan, Sarita S Hardas, Rukhsana Sultana, Peng Wu, Jason M Unrine, Uschi Graham, D Allan Butterfield, Eric A Grulke, Robert A Yoke. Alteration of hepatic structure and oxidative stress induced by intravenous nanoceria. Toxicology and applied pharmacology. vol 260. issue 2. 2012-08-30. PMID:22373796. |
a statistically significant elevation of serum aspartate aminotransferase (ast) level was seen at 1 and 20 h, but subsided by 30 days after ceria administration. |
2012-08-30 |
2023-08-12 |
rat |
| G Lippi, P Avanzini, M Cosmai, R Aloe, D Erns. Incomplete filling of lithium heparin tubes affects the activity of creatine kinase and gamma-glutamyltransferase. British journal of biomedical science. vol 69. issue 2. 2012-08-28. PMID:22872930. |
this study aims to assess whether or not incomplete filling of primary lithium heparin tubes may influence the activity of creatine kinase (ck), alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma-glutamyltransferase (ggt). |
2012-08-28 |
2023-08-12 |
human |
| Bendong Chen, Wenyan Zhou, Mingliang Ning, Zuozheng Wang, Lili Zou, Haihua Zhang, Qi Wan. Evaluation of antitumour activity of tea carbohydrate polymers in hepatocellular carcinoma animals. International journal of biological macromolecules. vol 50. issue 4. 2012-08-27. PMID:22406869. |
the altered amount of serum white blood cells (wbc), interferon-gamma (ifn-γ) and tumor necrosis factor-alpha (tnf-α) in hcc animals were dose-dependently increased, whereas activities of serum alanine transaminase (alt), aspartate transaminase (ast) and alkaline phosphatase (alp) were dose-dependently decreased in the drug treated animals. |
2012-08-27 |
2023-08-12 |
Not clear |
| M Saravanan, K Usha Devi, A Malarvizhi, M Rames. Effects of Ibuprofen on hematological, biochemical and enzymological parameters of blood in an Indian major carp, Cirrhinus mrigala. Environmental toxicology and pharmacology. vol 34. issue 1. 2012-08-27. PMID:22418069. |
on the other hand, a mixed trend was noticed in aspartate aminotransaminase (ast) enzyme activity. |
2012-08-27 |
2023-08-12 |
human |
| Guangde Yang, Zhiyuan Fang, Yu Liu, Hui Zhang, Xiaolian Shi, Qiaoli Ji, Qinqin Lin, Rong Li. Protective effects of chinese traditional medicine buyang huanwu decoction on myocardial injury. Evidence-based complementary and alternative medicine : eCAM. vol 2011. 2012-08-23. PMID:19204010. |
electrocardiogram (ecg) of each animal was recorded; activities of lactate dehydrogenase (ldh), creatine kinase (ck) and aspartate aminotransferase (ast) in serum were detected. |
2012-08-23 |
2023-08-12 |
rat |
| Mei-Ling Liu, Li-Yin Chien, Cheng-Jeng Tai, Kuan-Chia Lin, Chen-Jei Ta. Effectiveness of Traditional Chinese Medicine for Liver Protection and Chemotherapy Completion among Cancer Patients. Evidence-based complementary and alternative medicine : eCAM. vol 2011. 2012-08-23. PMID:19920087. |
outcome variables included counts of cancelled or delayed chemotherapies and liver function (aspartate aminotransferase, ast and alanine aminotransferase, alt) 1 week before, during and 2 weeks after chemotherapy. |
2012-08-23 |
2023-08-12 |
Not clear |
| K Severin, T Mašek, Z Janicki, D Konjević, A Slavica, A Marinculić, F Martinković, G Vengušt, P Džaj. Liver enzymes and blood metabolites in a population of free-ranging red deer (Cervus elaphus) naturally infected with Fascioloides magna. Journal of helminthology. vol 86. issue 2. 2012-08-23. PMID:21729388. |
the number of immature flukes was positively correlated with values of aspartate aminotransferase (ast), γ-glutamyltransferase (ggt), ldh, gldh, urea and triglycerides. |
2012-08-23 |
2023-08-12 |
Not clear |
| Tao Liu, Jun Zhao, Long Ma, Yusong Ding, Deqi S. Hepatoprotective Effects of Total Triterpenoids and Total Flavonoids from Vitis vinifera L against Immunological Liver Injury in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-08-23. PMID:22262981. |
various dose groups (50, 150, and 300 mg/kg) of vtt and vtf alleviated the degree of liver injury of ili mice, effectively reduced the bcg/lps-induced elevated liver index and spleen index, hepatic nitric oxide (no), and malondialdehyde (mda) content, increased liver homogenate alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, and restored hepatic superoxide dismutase (sod) activity in ili mice. |
2012-08-23 |
2023-08-12 |
mouse |
| Srinivas B Narayan, Stephen R Master, Anthony N Sireci, Charlene Bierl, Paige E Stanley, Changhong Li, Charles A Stanley, Michael J Bennet. Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways. PloS one. vol 7. issue 4. 2012-08-23. PMID:22496890. |
as an example, in murine liver, we find schad interaction with aspartate transaminase (ast) and gdh from amino acid metabolic pathways, carbamoyl phosphate synthase i (cps-1) from ureagenesis, other fatty acid oxidation and ketogenesis enzymes and fructose-bisphosphate aldolase, an extra-mitochondrial enzyme of the glycolytic pathway. |
2012-08-23 |
2023-08-12 |
Not clear |
| B Ragavan, S Krishnakumar. Effect of terminalia arjuna stem bark extract on the activities of marker enzymes in alloxan induced diabetic rats. Ancient science of life. vol 25. issue 1. 2012-08-23. PMID:22557182. |
t. arjuna was administered orally at a doses of 250 and 500 mg/kg body weight for 30 days, after which serum liver and kidney tissues were assayed for the degree of pathological changes by means of markers such as alkaline phosphatase (alp), acid phosphatase (acp), alanine amino transferase (alt), aspartate amino transferase (ast) and lactate dehydrogenase (ldh) resulted in a significant reduction in serum and tissue of liver and kidney marker enzymes when compared with control rats t. arjuna at a dose of 500 mg/kg body weight exhibited higher efficacy. |
2012-08-23 |
2023-08-12 |
rat |
| C Gokilaveni, A Nishadh, V Selv. AMELIORATIVE ROLE OF Vernonia cinerea IN CARBON TETRACHLORIDE INDUCED HEPATIC DYSFUNCTION IN RATS. Ancient science of life. vol 25. issue 3-4. 2012-08-23. PMID:22557198. |
the liver marker enzymes namely alanine transmainase (alt), aspartate transaminase (ast), acid phosphatase and alkaline phosphatase (alp) activities were decreased in 10% w/v liver homogenates of hepatotoxicity induced rats. |
2012-08-23 |
2023-08-12 |
rat |
| D Devipriya, S Gowri, T R Nidees. Hepatoprotective effect of Pterocarpus marsupium against carbon tetrachloride induced damage in albino rats. Ancient science of life. vol 27. issue 1. 2012-08-23. PMID:22557255. |
levels of marker enzymes such as alanine transminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), and lactate dehydrogenase (ldh) and bilirubin were increased significantly in group ii. |
2012-08-23 |
2023-08-12 |
human |