| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Won Sohn, Dae Won Jun, Min Jung Kwak, Quehn Park, Kang Nyeong Lee, Hang Lak Lee, Oh Young Lee, Byung Chul Yoon, Ho Soon Cho. Upper limit of normal serum alanine and aspartate aminotransferase levels in Korea. Journal of gastroenterology and hepatology. vol 28. issue 3. 2013-08-26. PMID:22497339. |
both alt and aspartate aminotransferase (ast) are commonly used as surrogate markers of liver disease, but almost all studies of aminotransferase activity were conducted on alt. |
2013-08-26 |
2023-08-12 |
Not clear |
| Vijayasteltar B Liju, Kottarapat Jeena, Ramadasan Kutta. Acute and subchronic toxicity as well as mutagenic evaluation of essential oil from turmeric (Curcuma longa L). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 53. 2013-08-26. PMID:23201370. |
indicators of hepatic function such as aspartate aminotransferase (ast), alanine amino transferase (alt) and alkaline phosphatase (alp) were unchanged in treated animals compared to untreated animals. |
2013-08-26 |
2023-08-12 |
rat |
| Xin Wu, Jun Zeng, Jinsong Hu, Qiong Liao, Rong Zhou, Ping Zhang, Zuohong Che. Hepatoprotective effects of aqueous extract from Lingzhi or Reishi medicinal mushroom Ganoderma lucidum (higher basidiomycetes) on α-amanitin-induced liver injury in mice. International journal of medicinal mushrooms. vol 15. issue 4. 2013-08-26. PMID:23796220. |
α-ama induced a significant elevation in serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities and provoked a significant reduction of superoxide dismutase (sod) and catalase (cat) activities and a significant increment of malondialdehyde (mda) content in liver homogenate. |
2013-08-26 |
2023-08-12 |
mouse |
| R U Khan, Z U Rahman, I Javed, F Muhamma. Effect of vitamins, probiotics and protein level on semen traits and seminal plasma biochemical parameters of post-moult male broiler breeders. British poultry science. vol 54. issue 1. 2013-08-23. PMID:23444861. |
seminal plasma was separated to determine the concentration of total antioxidant capacity (tac), homocysteine, paraoxonase (pon1), arylesterase, ceruloplasmin, aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities. |
2013-08-23 |
2023-08-12 |
Not clear |
| Omar M E Abdel-Salam, Eman R Youness, Nadia A Mohammed, Mehrevan Abd-Elmoniem, Enayat Omara, Amany A Slee. Neuroprotective and hepatoprotective effects of micronized purified flavonoid fraction (Daflon®) in lipopolysaccharide-treated rats. Drug discoveries & therapeutics. vol 6. issue 6. 2013-08-21. PMID:23337818. |
serum aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase (alp) were raised by 101.8, 93.6, and 223.2%, respectively. |
2013-08-21 |
2023-08-12 |
rat |
| Hanan H Haga. An insight into the possible protective effect of pyrrolidine dithiocarbamate against lipopolysaccharide-induced oxidative stress and acute hepatic injury in rats. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 17. issue 4. 2013-08-20. PMID:23960709. |
saline-pretreated animals challenged with lps revealed extensive liver damage, as evidenced by increases in serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma glutamyl transferase (γ-gt). |
2013-08-20 |
2023-08-12 |
rat |
| Nora A Al-Faris, Ali D Al-Sawadi, Majed S Alokai. Effect of samh seeds supplementation (Mesembryanthemum forsskalei Hochst) on liver enzymes and lipid profiles of streptozotocin (STZ)-induced diabetic Wistar rats. Saudi journal of biological sciences. vol 17. issue 1. 2013-08-20. PMID:23961054. |
at the end of the study, aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phophatase (alp) and lactate dehydrogenase (ldh) enzymes have been measured in diabetic rats liver. |
2013-08-20 |
2023-08-12 |
rat |
| M A Dkhil, S Al-Quraishy, A S Abdel-Bak. Hepatic tissue damage induced in Meriones ungliculatus due to infection with Babesia divergens-infected erythrocytes. Saudi journal of biological sciences. vol 17. issue 2. 2013-08-20. PMID:23961068. |
liver enzymes aspartate aminotransferase (ast) and aniline aminotransferase (alt) were significantly increased while albumin and total bilirubin were significantly decreased at day 5 postinfection with b. divergens-infected erythrocytes. |
2013-08-20 |
2023-08-12 |
Not clear |
| Bashir M Jarra. Histological alterations and biochemical changes in the liver of sheep following Echis coloratus envenomation. Saudi journal of biological sciences. vol 18. issue 2. 2013-08-20. PMID:23961120. |
e. coloratus venom elevated glucose, aspartate aminotransferase (ast), alanine aminotransferase (alt), triglyceride and total bilirubin while cholesterol was reduced. |
2013-08-20 |
2023-08-12 |
human |
| Jehad M Youse. Identifying frankincense impact by biochemical analysis and histological examination on rats. Saudi journal of biological sciences. vol 18. issue 2. 2013-08-20. PMID:23961123. |
after 15 and 30 days of treatment, the rats were anesthetized with ether, and blood was collected from the livers and kidneys; some biochemical analyses were performed including aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp) and non-bilirubin, urea, uric acid, and creatinine. |
2013-08-20 |
2023-08-12 |
rat |
| Atef M Al-Atta. Vitamin E attenuates liver injury induced by exposure to lead, mercury, cadmium and copper in albino mice. Saudi journal of biological sciences. vol 18. issue 4. 2013-08-20. PMID:23961152. |
significant increases of blood alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), gamma glutamyl transferase (ggt) were detected in heavy metals-treated mice. |
2013-08-20 |
2023-08-12 |
mouse |
| Mohamed K Al-Sadoon, Assem Fahi. Possible recovery from an acute envenomation in male rats with LD50 of Echis coloratus crude venom: I-A seven days hematological follow-up study. Saudi journal of biological sciences. vol 19. issue 2. 2013-08-20. PMID:23961182. |
the effect of an acute ld50 dose of echis coloratus crude venom in male albino rats was tested on blood parameters: white blood cells (wbcs), red blood cells (rbcs), platelets count, hemoglobin, hematocrit, mean cell volume (mcv), mean cell hemoglobin (mch) and mean cell hemoglobin concentration (mchc), also serum glucose, total protein, triglycerides with alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp) and γ-glutamyl transferase (ggt) enzyme activities. |
2013-08-20 |
2023-08-12 |
rat |
| S Milton Prabu, M Muthumani, K Shagirth. Protective effect of Piper betle leaf extract against cadmium-induced oxidative stress and hepatic dysfunction in rats. Saudi journal of biological sciences. vol 19. issue 2. 2013-08-20. PMID:23961183. |
oral administration of cd (5 mg/kg bw) for four weeks to rats significantly (p > 0.05) elevated the level of serum hepatic markers such as serum aspartate transaminase (ast), serum alanine transaminase (alt), alkaline phosphatase (alp), lactate dehydrogenase (ldh), gamma-glutamyl transpeptidase (ggt), bilirubin (tbrns), oxidative stress markers viz., thiobarbituric acid reactive substances (tbars), lipid hydroperoxides (looh), protein carbonyls (pc) and conjugated dienes (cd) and significantly (p > 0.05) reduced the enzymatic antioxidants viz., superoxide dismutase (sod), catalase (cat), glutathione peroxidase (gpx), glutathione s-transferase (gst), glutathione reductase (gr) and glucose-6-phosphate dehydrogenase (g6pd) and non-enzymatic antioxidants viz., reduced glutathione (gsh), total sulfhydryls (tsh), vitamin c and vitamin e in the liver. |
2013-08-20 |
2023-08-12 |
rat |
| Item J Atangwho, Emmanuel E Edet, Daniel E Uti, Augustine U Obi, Mohd Z Asmawi, Mariam Ahma. Biochemical and histological impact of Vernonia amygdalina supplemented diet in obese rats. Saudi journal of biological sciences. vol 19. issue 3. 2013-08-20. PMID:23961200. |
va diet also exerted hepato-protection, via lowering serum alanine amino transaminase (alt) (41.35% and 27.13%) and aspartate amino transaminase (ast) (17.09% and 43.21%) activities (p < 0.05). |
2013-08-20 |
2023-08-12 |
rat |
| Ping-Wei Zhao, Fei-Yong Jia, Yu-Xing Shan, Hui-Fan Ji, Jun-Yan Feng, Jun-Qi Niu, Desalegn A Ayana, Yan-Fang Jian. Downregulation and altered function of natural killer cells in hepatitis B virus patients treated with entecavir. Clinical and experimental pharmacology & physiology. vol 40. issue 3. 2013-08-16. PMID:23278368. |
concentrations of alanine aminotransferase (alt) and aspartate aminotransferase (ast), hbv viral loads in both groups and potential associations between the frequency of peripheral nk cell subsets and clinical measures were determined. |
2013-08-16 |
2023-08-12 |
Not clear |
| Wolfgang Sieghart, Florian Hucke, Matthias Pinter, Ivo Graziadei, Wolfgang Vogel, Christian Müller, Harald Heinzl, Michael Trauner, Markus Peck-Radosavljevi. The ART of decision making: retreatment with transarterial chemoembolization in patients with hepatocellular carcinoma. Hepatology (Baltimore, Md.). vol 57. issue 6. 2013-08-16. PMID:23316013. |
the increase of aspartate aminotransferase (ast) by >25% (hazard ratio [hr] 8.4; p < 0.001), an increase of child-pugh score of 1 (hr 2.0) or ≥2 points (hr 4.4) (p < 0.001) from baseline, and the absence of radiologic tumor response (hr 1.7; p = 0.026) remained independent negative prognostic factors for os and were used to create the art score. |
2013-08-16 |
2023-08-12 |
Not clear |
| Elsa Dias, Mariana Gomes, Catarina Domingues, Elmano Ramalheira, Simone Morais, Maria de Lourdes Pereir. Subacute effects of the thiodicarb pesticide on target organs of male Wistar rats: biochemical, histological, and flow cytometry studies. Journal of toxicology and environmental health. Part A. vol 76. issue 9. 2013-08-13. PMID:23750999. |
aspartate aminotransferase (ast) activity increased (group a at 20 d; groups a and b at 30 d) and alkaline phosphatase (alp) (group b at 30 d) activity significantly reduced. |
2013-08-13 |
2023-08-12 |
rat |
| Tingfen Li, Yongmin Yan, Bingying Wang, Hui Qian, Xu Zhang, Li Shen, Mei Wang, Ying Zhou, Wei Zhu, Wei Li, Wenrong X. Exosomes derived from human umbilical cord mesenchymal stem cells alleviate liver fibrosis. Stem cells and development. vol 22. issue 6. 2013-08-12. PMID:23002959. |
hucmsc-ex also significantly recovered serum aspartate aminotransferase (ast) activity, decreased collagen type i and iii, transforming growth factor (tgf)-β1 and phosphorylation smad2 expression in vivo. |
2013-08-12 |
2023-08-12 |
human |
| Takuya Kitamoto, Aya Kitamoto, Masato Yoneda, Hideyuki Hyogo, Hidenori Ochi, Takahiro Nakamura, Hajime Teranishi, Seiho Mizusawa, Takato Ueno, Kazuaki Chayama, Atsushi Nakajima, Kazuwa Nakao, Akihiro Sekine, Kikuko Hott. Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan. Human genetics. vol 132. issue 7. 2013-08-12. PMID:23535911. |
these snps were found to be in the same linkage disequilibrium block and were associated with decreased serum triglycerides and increased aspartate aminotransferase (ast) and alanine aminotransferase (alt) in nafld patients. |
2013-08-12 |
2023-08-12 |
human |
| Arpita Basu, Emily D Newman, Alecia L Bryant, Timothy J Lyons, Nancy M Bett. Pomegranate polyphenols lower lipid peroxidation in adults with type 2 diabetes but have no effects in healthy volunteers: a pilot study. Journal of nutrition and metabolism. vol 2013. 2013-08-12. PMID:23936637. |
however, aspartate aminotransferase (ast) showed a significant increase in healthy controls, while alanine aminotransferase (alt) was significantly decreased in t2dm patients at 4 weeks (p < 0.05), though values remained within the normal ranges. |
2013-08-12 |
2023-08-12 |
human |