| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sana Rafaqat, Aqsa Sattar, Amber Khalid, Saira Rafaqa. Role of liver parameters in diabetes mellitus - a narrative review. Endocrine regulations. vol 57. issue 1. 2023-09-16. PMID:37715985. |
this review article focuses on various liver parameters, including albumin, alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), alpha fetoprotein (afp), alpha 1 antitrypsin (aat), ammonia, bilirubin, bile acid, gamma-glutamyl transferase (ggt), immunoglobulin, lactate dehydrogenase (ldh), and total protein. |
2023-09-16 |
2023-10-07 |
Not clear |
| Lu Zhang, Shaowen Shi, Ying Liu, Yuqing Cui, Yixuan Zhu, Yongzhan Bao, Baojiang Chen, Wanyu Sh. Aflatoxin B1 triggers apoptosis in rabbit hepatocytes via mediating oxidative stress and switching on the mitochondrial apoptosis pathway. Ecotoxicology and environmental safety. vol 264. 2023-09-16. PMID:37716070. |
additionally, afb1 exposure was associated with increased activity of aspartate aminotransferase (ast) and alanine aminotransferase (alt), as well as decreased levels of total protein (tp) and albumin (alb) in the serum. |
2023-09-16 |
2023-10-07 |
rabbit |
| Yozo Mitsui, Fumito Yamabe, Shunsuke Hori, Masato Uetani, Hiroshi Aoki, Kei Sakurabayashi, Mizuho Okawa, Hideyuki Kobayashi, Koichi Nagao, Koichi Nakajim. Longitudinal change in castration-resistant prostate cancer biomarker AST/ALT ratio reflects tumor progression. Scientific reports. vol 13. issue 1. 2023-09-15. PMID:37714917. |
we investigated whether aspartate transaminase (ast)-to-alanine aminotransferase (alt) ratio and its change during the course of treatment in castration-resistant prostate cancer (crpc) patients is associated with tumor condition and lethality. |
2023-09-15 |
2023-10-07 |
Not clear |
| Mehmet Ali Yesiltas, A K Hulya Yilmaz, Yasemin Ozsahin, Baris Sandal, Ziya Salihoglu, Kerem Erkal. The effect of postoperative hepatic fibrosis factors on morbidity in mitral valve replacement surgery: A single center ten years' experience. Annals of cardiac anaesthesia. vol 26. issue 2. 2023-09-14. PMID:37706385. |
our aim with this study was to investigate the effect of aspartate aminotransferase/alanine aminotransferase (ast/alt) ratio and fibrosis-4 (fib-4) index calculated with alt, ast, and platelet biomarkers, which are simple, fast, and relatively inexpensive and were used in previous studies to predict cardiovascular disease prognosis, on the prediction of postoperative morbidity and early mortality after mitral valve replacement (mvr) surgery. |
2023-09-14 |
2023-10-07 |
Not clear |
| Prasad M Govindaiah, Naveena B Maheswarappa, Rituparna Banerjee, Bidyut Prava Mishra, Balaji B Manohar, Sowmya Dasoj. Traditional halal meat production without stunning versus commercial slaughter with electrical stunning of slow-growing broiler chicken: impact on meat quality and proteome changes. Poultry science. vol 102. issue 11. 2023-09-14. PMID:37708767. |
the st group had higher (p < 0.05) creatinine, total protein, alanine aminotransferase (alt), and triiodothyronine (t3) than nst group, however, no difference (p > 0.05) in blood glucose, lactate dehydrogenase (ldh), creatine kinase (ck), thyroxine (t4), cortisol, and aspartate aminotransferase (ast) was observed relative to nst samples. |
2023-09-14 |
2023-10-07 |
chicken |
| Shuaiwen Li, Zihui Chen, Feng Yang, Wanqing Yu. Self-template sacrifice and in situ oxidation of a constructed hollow MnO Analytica chimica acta. vol 1278. 2023-09-14. PMID:37709473. |
here, we introduce a novel approach to develop a smartphone-assisted portable colorimetric sensor for rapid detection of three liver function biomarkers: aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp). |
2023-09-14 |
2023-10-07 |
Not clear |
| Xi Cao, Yongli Xie, Chunlei Zhou, Hong M. Clinical characteristics associated with recurrent viral RNA positivity in patients within two weeks after recovering from the first SARS-CoV-2 infection. Biomolecules & biomedicine. 2023-09-13. PMID:37702601. |
significant differences were observed in age, alanine aminotransferase (alt), aspartate aminotransferase (ast), c-reactive protein (crp), interleukin 6 (il6), and neutrophil to lymphocyte ratio (nlr) levels between the mild-adult group and the moderate-adult group (p < 0.05). |
2023-09-13 |
2023-10-07 |
human |
| Xiaofan Feng, Yanan Zhou, Shujie Pang, Chun Yang, Siyuan Wan. Phosphotriesterase-related protein as a novel prognostic predictor for hepatocellular carcinoma patients. Chinese clinical oncology. vol 12. issue 4. 2023-09-12. PMID:37699602. |
phosphotriesterase-related (pter) protein, an expressed protein in the liver and injured or ploycystic kidneys, was reported to be correlated with serum aspartate aminotransferase (ast) and alanine transaminase (alt). |
2023-09-12 |
2023-10-07 |
Not clear |
| Hisayuki Katsuyama, Hidekatsu Yanai, Hiroki Adachi, Mariko Hakoshim. A Significant Effect of Pemafibrate on Hepatic Steatosis and Fibrosis Indexes in Patients With Hypertriglyceridemia. Gastroenterology research. vol 16. issue 4. 2023-09-11. PMID:37691751. |
we previously reported that the selective peroxisome proliferator-activated receptor alpha modulator, pemafibrate, significantly reduced serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt) and gamma-glutamyl transferase (ggt) and significantly increased serum albumin levels at 3, 6 and 12 months after the start of pemafibrate, with an improvement of atherogenic dyslipidemia, in patients with hypertriglyceridemia. |
2023-09-11 |
2023-10-07 |
Not clear |
| Seyed Amirsajjad Alami, Aryan Payrovnaziri, Saeed Seghatoleslami, Sara Faraji, Fatemeh Rahimzadeh Bajgiran, Mahsa Rastegar Moghaddam Poorbagher, Negin Shafaei, Ehsan Karimi, Ehsan Oskoueia. The anti-spermatogenic activity of nanoliposomes loaded with Heracleum persicum phenolic compounds in Balb/C mice. Biotechnology and applied biochemistry. 2023-09-11. PMID:37694540. |
the 18 white male balb/c mice (20-25 g) at 3 treatment groups were provided to study the nl-hppf cytotoxicity by measuring the mice liver enzyme including aspartate aminotransferase (ast), alp and alanine aminotransferase (alt), testis lipid peroxidation, and testicular tissue destruction levels. |
2023-09-11 |
2023-10-07 |
mouse |
| Xi Meng, Guoqi Yu, Tingyu Luo, Ruiyuan Zhang, Jun Zhang, Yongjie Li. Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring. Chemosphere. 2023-09-11. PMID:37696479. |
although the biochemical index difference including total cholesterol (tc), triglyceride (tg), high-density lipoprotein (hdl), low-density lipoprotein (ldl), alanine amino transaminase (alt), aspartate amino transferase (ast), and fasting blood glucose between exposed groups and the control group was not significant, transcriptome analyses showed that the differentially expressed genes (degs) in the 50 mg/kg/day pfbs exposure group were significantly related to protein digestion and absorption, peroxisome proliferator activated-receptor (ppar) signaling pathway, xenobiotic metabolism by cytochrome p450, glycine, serine and threonine metabolism, β-alanine metabolism, bile secretion, unsaturated fatty acid (fa) biosynthesis, and alanine, aspartate and glutamate metabolism. |
2023-09-11 |
2023-10-07 |
rat |
| Manaswita Tappata, Marina Farah, Chimaobi Anugwom, Eden Bisrat, Amir S Seid, Jose D Debe. Clinical, Gender, Socioeconomic Characteristics and Outcomes of Individuals Receiving Hepatitis B Treatment in Ethiopia: 18-Month Follow-Up. The American journal of tropical medicine and hygiene. 2023-09-11. PMID:37696510. |
individuals on treatment had higher median aspartate aminotransferase (ast), alanine aminotransferase (alt), hbv dna, and median aminotransferase-to-platelet ratio index and fibrosis-4 scores. |
2023-09-11 |
2023-10-07 |
Not clear |
| D Giannuzzi, F Piccioli-Cappelli, S Pegolo, V Bisutti, S Schiavon, L Gallo, A Toscano, P Ajmone Marsan, L Cattaneo, E Trevisi, A Cecchinat. Observational study on the associations between milk yield, composition and coagulation properties with blood biomarkers of health in Holstein cows. Journal of dairy science. 2023-09-10. PMID:37690724. |
our findings revealed that milk yield and dmeo are positively and linearly associated with total cholesterol, nonesterified fatty acids (nefa), urea, aspartate aminotransferase (ast), γ-glutamyl transferase (ggt), total bilirubin, albumin, and ferric-reducing antioxidant power (frap), whereas they are negatively associated with glucose, creatinine, alkaline phosphatase, total reactive oxygen metabolites (romt), and proinflammatory proteins (i.e., ceruloplasmin, haptoglobin, and myeloperoxidase). |
2023-09-10 |
2023-10-07 |
Not clear |
| Tae-Geom Lee, Pil-Gyu Park, Yong-Beom Park, Ji-Hye Huh, Sang-Won Le. Clinical Link between the BARD Score at Diagnosis and Mortality during Follow-Up in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Journal of clinical medicine. vol 12. issue 17. 2023-09-09. PMID:37685746. |
the bard score was calculated by the sum of aspartate transaminase (ast)/alanine transaminase (alt) ratio ≥ 0.8 (+2 points), body mass index (bmi) ≥ 28 kg/m |
2023-09-09 |
2023-10-07 |
Not clear |
| Stamatina Vogli, Androniki Naska, Georgios Marinos, Maria-Iosifina Kasdagli, Philippos Orfano. The Effect of Vitamin E Supplementation on Serum Aminotransferases in Non-Alcoholic Fatty Liver Disease (NAFLD): A Systematic Review and Meta-Analysis. Nutrients. vol 15. issue 17. 2023-09-09. PMID:37686767. |
regarding aspartate aminotransferase (ast), patients in the experimental group experienced a reduction in serum levels, though smaller in absolute values [ast md = -4.65 iu/l, 95% ci (-7.44, -1.86) in studies conducted in asian populations] and of lower precision in non-asian studies [md = -5.60 iu/l, 95% ci (-11.48, 0.28)]. |
2023-09-09 |
2023-10-07 |
Not clear |
| Weikun Huang, Cong Xie, Nicolai J Wewer Albrechtsen, Miaomiao Sang, Zilin Sun, Karen L Jones, Michael Horowitz, Christopher K Rayner, Tongzhi W. Serum alanine transaminase is predictive of fasting and postprandial insulin and glucagon concentrations in type 2 diabetes. Peptides. 2023-09-06. PMID:37673303. |
serum liver enzyme levels, including alanine transaminase (alt), aspartate transaminase (ast) and gamma-glutamyl transferase (ggt), are reportedly predictive of the risk of t2d. |
2023-09-06 |
2023-10-07 |
human |
| Noura S Abouzeinab, Nour Kahil, Najla Fakhruddin, Ramadan Awad, Mahmoud I Khali. Intraperitoneal hepato-renal toxicity of zinc oxide and nickel oxide nanoparticles in male rats: biochemical, hematological and histopathological studies. EXCLI journal. vol 22. 2023-09-04. PMID:37662710. |
the experimental groups exhibited elevated levels of aspartate aminotransferase (ast), alanine transaminase (alt), creatinine (crea), urea, lipid profile, glucose (glu), total protein (tp), albumin (alb) and malondialdehyde (mda), and decreased uric acid (ua), superoxide dismutase (sod), and glutathione (gsh). |
2023-09-04 |
2023-09-07 |
human |
| Mahmoud H Hatab, Aml M M Badran, Mahmoud A Elaroussi, Eman Rashad, Adel M Abu Taleb, Abdelmotaleb A Eloki. Effect of Zinc Oxide Nanoparticles as Feed Additive on Blood Indices, Physiological, Immunological Responses, and Histological Changes in Broiler Chicks. Biological trace element research. 2023-09-04. PMID:37667095. |
a significant increase in the concentrations of hemoglobin (hb), hematocrit (pcv%), red and white blood cell counts, total protein (tp), globulin (glob), aspartate transferase (ast), alanine transferase (alt), alkaline phosphatase (alp), superoxide dismutase (sod), glutathione peroxidase (gpx), and total antioxidant capacity (tac) and a significant decrease in malonaldehyde (mda), uric acid, and creatinine concentration were observed. |
2023-09-04 |
2023-09-07 |
Not clear |
| Qian Du, Mengmeng Teng, Luting Yang, Chao Meng, Yulan Qiu, Chuhui Wang, Jiaojiao Chen, Taotao Wang, Siying Chen, Yu Luo, Jinyao Sun, Yalin Don. Metabolic characteristics of voriconazole - Induced liver injury in rats. Chemico-biological interactions. 2023-09-02. PMID:37659626. |
vor - induced liver injury in rats was characterized by plasma alanine aminotransferase (alt) and aspartate aminotransferase (ast) elevation, the lipid droplets accumulation in liver, as well as inflammation and fibrosis. |
2023-09-02 |
2023-09-07 |
rat |
| Yuping Ding, Zuoyu Wang, Haiyan Niu, Quanjun Deng, Yanan Wang, Shihai Xi. FIB-4 is closer to FibroScan screen results to detecting advanced liver fibrosis and maybe facilitates NAFLD warning. Medicine. vol 102. issue 34. 2023-09-01. PMID:37653822. |
the magnitude of liver stiffness measured using fibroscan was positively correlated with aspartate transaminase/alanine aminotransferase (ast/alt) ratio (r = 0.419, p = .000), ast to platelet ratio index (apri) score (r = 0.309, p = .000), and fibrosis-4 score (fib-4) (r = 0.507, p = .000). |
2023-09-01 |
2023-09-07 |
Not clear |