| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yin-Hua Xiong, Ying Xu, Li Yang, Zheng-Tao Wan. Gas chromatography-mass spectrometry-based profiling of serum fatty acids in acetaminophen-induced liver injured rats. Journal of applied toxicology : JAT. vol 34. issue 2. 2014-08-26. PMID:23239188. |
the serum concentrations of c18:1n9, c18:2n6 and c22:6n3 were all positively correlated (r > 0.8; pearson's correlation analysis) with the activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2014-08-26 |
2023-08-12 |
rat |
| Xiaowei Sun, Wei Xu, Yan Zeng, Yurong Hou, Lin Guo, Xiujuan Zhao, Changhao Su. Metabonomics evaluation of urine from rats administered with phorate under long-term and low-level exposure by ultra-performance liquid chromatography-mass spectrometry. Journal of applied toxicology : JAT. vol 34. issue 2. 2014-08-26. PMID:23280859. |
compared with the control group, serum aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (tbil), urea nitrogen (bun) and creatinine (cr) were increased in the middle- and high-dose groups whereas albumin (alb) and cholinesterase (che) were decreased. |
2014-08-26 |
2023-08-12 |
rat |
| Hong Wang, Li Xue, Rong Yan, Yin Zhou, Ming-Shan Wang, Mei-Juan Cheng, Hai-Jun Huan. Comparison of histologic characteristics of Chinese chronic hepatitis B patients with persistently normal or mildly elevated ALT. PloS one. vol 8. issue 11. 2014-08-26. PMID:24260428. |
alt, aspartate aminotransferase (ast), and hbv dna levels were some of the other parameters measured. |
2014-08-26 |
2023-08-12 |
Not clear |
| Mei Xue, Zhen-zhou Jiang, Tao Wu, Ji Li, Liang Zhang, Yan Zhao, Xue-jun Li, Lu-Yong Zhang, Shu-yu Yan. Anti-inflammatory effects and hepatotoxicity of Tripterygium-loaded solid lipid nanoparticles on adjuvant-induced arthritis in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 19. issue 11. 2014-08-25. PMID:22884304. |
the serum alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), γ-glutamyl transpeptidase (ggt), total bilirubin (tbil) and albumin (alb) levels were evaluated by an autoanalyzer. |
2014-08-25 |
2023-08-12 |
rat |
| Lingyuan Xu, Ni Zheng, Qiaoling He, Rong Li, Kefeng Zhang, Tao Lian. Puerarin, isolated from Pueraria lobata (Willd.), protects against hepatotoxicity via specific inhibition of the TGF-β1/Smad signaling pathway, thereby leading to anti-fibrotic effect. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 20. issue 13. 2014-08-25. PMID:23856441. |
our results showed that the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), hyaluronic acid (ha), laminin (ln), type iii precollagen (pciii) and type iv collagen (civ) were significantly reduced by pr treatment, while hepatic homogenates showed decreased levels of hydroxyproline (hyp) and collagen i (col i). |
2014-08-25 |
2023-08-12 |
rat |
| Tatiane Cristina dos Santos Bonfim, Arnaldo Maldonado, Victor Menezes Tunholi, Vinícius Menezes Tunholi-Alves, Marta Julia Faro, Esther Maria Mota, Thatiane Cristina Barros da Silva, Jairo Pinheiro, Juberlan Silva Garci. Biochemical and histopathological alterations in Biomphalaria glabrata due to co-infection by Angiostrongylus cantonensis and Echinostoma paraensei. Journal of invertebrate pathology. vol 115. 2014-08-25. PMID:24513030. |
the effect of concurrent infection by echinostoma paraensei and angiostrongylus cantonensis on the activity of the enzymes alanine aminotransferase (alt) and aspartate aminotransferase (ast) and the concentration of total proteins, uric acid and urea in the hemolymph of biomphalaria glabrata were investigated. |
2014-08-25 |
2023-08-12 |
Not clear |
| Charlotte de Jonge, Sander S Rensen, Ger H Koek, Mandy F Joosten, Wim A Buurman, Nicole D Bouvy, Jan Willem M Grev. Endoscopic duodenal-jejunal bypass liner rapidly improves plasma parameters of nonalcoholic fatty liver disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. vol 11. issue 11. 2014-08-20. PMID:23920034. |
before, during, and after djbl implantation, we determined plasma levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), γ-glutamyltransferase (γ-gt), albumin, caspase-cleaved cytokeratin-18 (ck-18), and liver fatty acid-binding protein (l-fabp). |
2014-08-20 |
2023-08-12 |
human |
| Yuan-yuan Zhang, Bo Liu, Xian-ping Ge, Wen-bin Liu, Jun Xie, Mingchun Ren, Yan-ting Cui, Si-lei Xia, Ruli Chen, Qunlan Zhou, Liangkun Pan, Yebing Y. The influence of various feeding patterns of emodin on growth, non-specific immune responses, and disease resistance to Aeromonas hydrophila in juvenile Wuchang bream (Megalobrama amblycephala). Fish & shellfish immunology. vol 36. issue 1. 2014-08-18. PMID:24211853. |
significantly higher levels (p < 0.05) of plasma aspartate aminotransferase (ast) and alanine aminotransferase (alt) activity were observed in p2 and p4 treatment groups when compared with the control group, while no significant differences were observed in the ast and alt activity of fish in p2, p3, p4 and p5 treatment groups. |
2014-08-18 |
2023-08-12 |
Not clear |
| C Thanpari, M K Shrewastwa, R Takhelmayum, N K Yadav, P Thapa, R K Mitta. Liver dysfunction in alcoholics in Western Nepal. Mymensingh medical journal : MMJ. vol 23. issue 2. 2014-08-18. PMID:24858167. |
a total of 150 alcoholic associated liver disorders patients aged between 20-70 years and 50 sex age matched normal healthy controls were taken to assess liver function tests (lfts) by measuring aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), gamma glutamyltranspeptidase (ggt) & albumin. |
2014-08-18 |
2023-08-13 |
human |
| Qun Lu, Li Yang, Hai-Yan Zhao, Jian-Guo Jiang, Xi-Lin X. Protective effect of compounds from the flowers of Citrus aurantium L. var. amara Engl against carbon tetrachloride-induced hepatocyte injury. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 62. 2014-08-15. PMID:23985451. |
htf, la also showed their capability of decreasing the ccl4-induced leakage of lactate dehydrogenase (ldh), aspartate aminotransferase (ast), inhibiting the lipid peroxidation, htf showed more significant activity. |
2014-08-15 |
2023-08-12 |
human |
| Satomi Onoue, Kiyoshi Yamamoto, Yohei Kawabata, Shizuo Yamad. In vitro/in vivo characterization of nanocrystalline formulation of tranilast with improved dissolution and hepatoprotective properties. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. vol 85. issue 3 Pt B. 2014-08-12. PMID:24055688. |
in a rat model of acute liver injury, repeated treatment with nc/tl (2 mg tl/kg) every 12h led to marked attenuation of hepatic damage as evidenced by decreases in alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), and total reactive oxygen species levels. |
2014-08-12 |
2023-08-12 |
rat |
| O M Bolaji, O O Olabod. Modulating effect of aqueous extract of Telfairia occidentalis on induced cyanide toxicity in rats. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 26. issue 2. 2014-08-08. PMID:22547189. |
biochemical analysis of liver enzymes showed that cyanide (group2) damaged the liver as there was significantly elevated presence (p<0.05) of aspartate aminotransferase (ast) and alanine aminotransferase (alp) above those of the control group. |
2014-08-08 |
2023-08-12 |
rat |
| Yanmang Cui, Yong Han, Xingbin Yang, Yanfei Sun, Yan Zha. Protective effects of quercetin and quercetin-5',8-disulfonate against carbon tetrachloride-caused oxidative liver injury in mice. Molecules (Basel, Switzerland). vol 19. issue 1. 2014-08-08. PMID:24378968. |
oral administration of both qs and the parent quercetin at 100, 200 and 500 mg/kg·bw prior to acute ccl4 oxidative damage in mice, effectively attenuated serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) activities and hepatic malondialdehyde (mda) levels (p<0.05), and suppressed the ccl4-induced depletion of glutathione peroxidase (gsh-px) and total superoxide dismutase (t-sod). |
2014-08-08 |
2023-08-12 |
mouse |
| Hiromitsu Kumada, Yoshiyuki Suzuki, Kenji Ikeda, Joji Toyota, Yoshiyasu Karino, Kazuaki Chayama, Yoshiiku Kawakami, Akio Ido, Kazuhide Yamamoto, Koichi Takaguchi, Namiki Izumi, Kazuhiko Koike, Tetsuo Takehara, Norifumi Kawada, Michio Sata, Hidetaka Miyagoshi, Timothy Eley, Fiona McPhee, Andrew Damokosh, Hiroki Ishikawa, Eric Hughe. Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection. Hepatology (Baltimore, Md.). vol 59. issue 6. 2014-08-08. PMID:24604476. |
the most common adverse events were nasopharyngitis, increased alanine aminotransferase (alt) and aspartate aminotransferase (ast), headache, diarrhea, and pyrexia. |
2014-08-08 |
2023-08-12 |
Not clear |
| Fu-Chao Liu, Yung-Fong Tsai, Huang-Ping Y. Maraviroc attenuates trauma-hemorrhage-induced hepatic injury through PPAR gamma-dependent pathway in rats. PloS one. vol 8. issue 10. 2014-08-07. PMID:24205332. |
plasma alanine aminotransferase (alt) with aspartate aminotransferase (ast) concentrations and various hepatic parameters were measured (n=8 rats/group) at 24 hours after resuscitation. |
2014-08-07 |
2023-08-12 |
rat |
| Guoqing Qian, Franklin Wang, Lili Tang, Michael E Massey, Nicole J Mitchell, Jianjia Su, Jonathan H Williams, Timothy D Phillips, Jia-Sheng Wan. Integrative toxicopathological evaluation of aflatoxin B₁ exposure in F344 rats. Toxicologic pathology. vol 41. issue 8. 2014-08-05. PMID:23423819. |
in single-dose protocol, serum aspartate transaminase (ast), alanine transaminase (alt), and alkaline phosphatase (alp) showed dose-related elevation, with maximal changes observed (>100-fold) at day 3 after treatment. |
2014-08-05 |
2023-08-12 |
rat |
| A Vidhya, V Renjugopal, M Indir. Impact of thiamine supplementation in the reversal of ethanol induced toxicity in rats. Indian journal of physiology and pharmacology. vol 57. issue 4. 2014-07-30. PMID:24968580. |
administration of ethanol at a dose of 4 g/kg body wt/day for 90 days to sprague dawley rats manifested chronic alcohol induced toxicity evidenced by decreased body weight, an increase in liver-body weight ratio, increase in activities of serum and liver aspartate transaminase (ast), alanine transaminase (alt), gamma-glutamyl transpeptidase (ggt); decrease in the activities of superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase in the liver and brain. |
2014-07-30 |
2023-08-13 |
rat |
| Jien-Wei Liu, Ing-Kit Lee, Lin Wang, Rong-Fu Chen, Kuender D Yan. The usefulness of clinical-practice-based laboratory data in facilitating the diagnosis of dengue illness. BioMed research international. vol 2013. 2014-07-29. PMID:24455678. |
we separately compared individual laboratory variables (platelet count [pc] , prothrombin time [pt], activated partial thromboplastin time [aptt], alanine aminotransferase [alt], and aspartate aminotransferase [ast]) and varied combined variables of df and/or dhf cases with the corresponding ones of nondengue cases. |
2014-07-29 |
2023-08-12 |
Not clear |
| Jeffrey L Reha, Sukhyung Lee, Luke J Hofman. Prevalence and predictors of nonalcoholic steatohepatitis in obese patients undergoing bariatric surgery: a Department of Defense experience. The American surgeon. vol 80. issue 6. 2014-07-29. PMID:24887798. |
on multivariate analysis, only elevated aspartate aminotransferase (ast) (greater than 41 iu/l) was the independent predictor for nash (odds ratio, 5.85; confidence interval, 1.06 to 32.41). |
2014-07-29 |
2023-08-13 |
Not clear |
| G Sesti, T V Fiorentino, M L Hribal, A Sciacqua, F Perticon. Association of hepatic insulin resistance indexes to nonalcoholic fatty liver disease and related biomarkers. Nutrition, metabolism, and cardiovascular diseases : NMCD. vol 23. issue 12. 2014-07-28. PMID:23419734. |
we examined the relationship between these indexes, nafld and its related biomarkers (alanine aminotransferase [alt], aspartate aminotransferase [ast], gamma-glutamyltransferase [ggt], alkaline phosphatase [alk], high-sensitive c reactive protein [hscrp], insulin-like growth factor-1 [igf-1]). |
2014-07-28 |
2023-08-12 |
Not clear |