| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xianwa Niu, Wen Hua Huang, Bastiaan De Boer, Luc Delriviere, Ling Jun Mou, Gary P Jeffre. Iron-induced oxidative rat liver injury after non-heart-beating warm ischemia is mediated by tumor necrosis factor α and prevented by deferoxamine. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 20. issue 8. 2015-04-21. PMID:24753220. |
aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) levels in the nhb perfusate were significantly elevated (p < 0.01) in comparison with levels in hb controls after cs and mrp. |
2015-04-21 |
2023-08-13 |
rat |
| Tomasz Chamera, Michał Spieszny, Tomasz Klocek, Dorota Kostrzewa-Nowak, Robert Nowak, Milena Lachowicz, Rafał Buryta, Paweł Cięszczy. Could biochemical liver profile help to assess metabolic response to aerobic effort in athletes? Journal of strength and conditioning research. vol 28. issue 8. 2015-04-21. PMID:25057846. |
plasma activity of aspartate aminotransferase (ast), alanine aminotransferase (alt), γ-glutamyltransferase (ggt) and plasma levels of total and direct bilirubin were determined in samples obtained before exercise test (pre-exercise) and immediately after the run (post-exercise). |
2015-04-21 |
2023-08-13 |
Not clear |
| Meejung Ahn, Jong Sang Park, Sungwook Chae, Seungjoon Kim, Changjong Moon, Jin Won Hyun, Taekyun Shi. Hepatoprotective effects of Lycium chinense Miller fruit and its constituent betaine in CCl4-induced hepatic damage in rats. Acta histochemica. vol 116. issue 6. 2015-04-20. PMID:24998029. |
the treatment of lc fruit extract significantly suppressed the increase of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in the sera of ccl4 injured rats, and restored the decreased levels of anti-oxidant enzymes such as total antioxidant capacity (tac), superoxide dismutase (sod), catalase (cat) and glutathione peroxidase (gpx) and suppressed the expression of inflammatory mediators including inducible nitric oxide synthase (inos) and cyclooxygenase (cox)-1 and -2. |
2015-04-20 |
2023-08-13 |
rat |
| Wan Yong Ho, SweeKeong Yeap, Woon San Liang, Boon Kee Beh, NurulElyani Mohamad, Noorjahan Banu Alithee. In vitro antioxidant and in vivo hepatoprotective effect on ethanol-mediated liver damage of spray dried Vernonia amygdalina water extract. Pakistan journal of pharmaceutical sciences. vol 28. issue 1. 2015-04-20. PMID:25553678. |
on the other hand, extracts at both 10 and 50 mg/kg body weight were able to reduce the levels of alanine transaminase (alt), alkaline phosphatase (alp), aspartate transaminase (ast), triglyceride and total bilirubin content inthe alcohol-mediated liver injury in mice. |
2015-04-20 |
2023-08-13 |
mouse |
| Jehad Mustafa Yousef, Azza Mostafa Mohame. Prophylactic role of B vitamins against bulk and zinc oxide nano-particles toxicity induced oxidative DNA damage and apoptosis in rat livers. Pakistan journal of pharmaceutical sciences. vol 28. issue 1. 2015-04-20. PMID:25553694. |
the results revealed that oral co-administration of combination of b vitamins (250 mg b(3), 60 mg b(6) and 0.6 mg b(12)/kg body weight) daily for 3 weeks to rats intoxicated by either zno- bulk or its nps markedly ameliorated increases in serum of alanine aminotransferase (alt), aspartate aminotransferase (ast) and lactate dehdrogenase (ldh). |
2015-04-20 |
2023-08-13 |
rat |
| I I Ahmetov, V A Naumov, A E Donnikov, A Maciejewska-Karłowska, E S Kostryukova, A K Larin, E V Maykova, D G Alexeev, O N Fedotovskaya, E V Generozov, Z Jastrzębski, P Zmijewski, O A Kravtsova, N A Kulemin, A Leonska-Duniec, D S Martykanova, E A Ospanova, A V Pavlenko, A A Podol'skaya, M Sawczuk, F K Alimova, D Y Trofimov, V M Govorun, P Cieszczy. SOD2 gene polymorphism and muscle damage markers in elite athletes. Free radical research. vol 48. issue 8. 2015-04-19. PMID:24865797. |
muscle and liver damage markers [creatine kinase (ck), creatinine, alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp)] were examined in serum from 1444 russian athletes. |
2015-04-19 |
2023-08-13 |
Not clear |
| Ajaz A Ganai, Athar A Khan, Zainul A Malik, Humaira Farooq. Genistein modulates the expression of NF-κB and MAPK (p-38 and ERK1/2), thereby attenuating d-Galactosamine induced fulminant hepatic failure in Wistar rats. Toxicology and applied pharmacology. vol 283. issue 2. 2015-04-17. PMID:25620059. |
the hepatoprotective and curative effects of genistein were evident from a significant decrease in the serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels as well as prevention of histological damage by pre-treatment of genistein. |
2015-04-17 |
2023-08-13 |
rat |
| Feng Gao, Yingchun Liu, Lingyao Li, Ming Li, Chongzhi Zhang, Changjin Ao, Xianzhi Ho. Effects of maternal undernutrition during late pregnancy on the development and function of ovine fetal liver. Animal reproduction science. vol 147. issue 3-4. 2015-04-16. PMID:24852270. |
in contrast, increases in fetal hepatic collagen fibers and reticular fibers, glutathione peroxidase (gsh-px), malondialdehyde (mda), nitric oxide (no), nitric oxide synthase (nos), monoamine oxidase (mao), albumin (alb)/glb, aspartate transaminase (ast), and ast/alt were found in the rg1 fetuses (p<0.05). |
2015-04-16 |
2023-08-13 |
Not clear |
| Allison J McGovern, Irena V Vitkovitsky, Daniel L Jones, Michael E Mullin. Can AST/ALT ratio indicate recovery after acute paracetamol poisoning? Clinical toxicology (Philadelphia, Pa.). vol 53. issue 3. 2015-04-15. PMID:25652258. |
elevations in aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels indicate hepatic toxicity. |
2015-04-15 |
2023-08-13 |
Not clear |
| Ali Akbar Malekirad, Mahya Faghih, Mansuoreh Mirabdollahi, Mahdi Kiani, Arezoo Fathi, Mohammad Abdollah. Neurocognitive, mental health, and glucose disorders in farmers exposed to organophosphorus pesticides. Arhiv za higijenu rada i toksikologiju. vol 64. issue 1. 2015-04-13. PMID:23705196. |
the subjects were also tested for fasting blood glucose (fbg), blood urea nitrogen (bun), cholesterol (cl), triglycerides (tg), creatinine, oral glucose tolerance test (gtt), high-density lipoprotein (hdl), aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp). |
2015-04-13 |
2023-08-12 |
human |
| P Zhao, K Zhang, Q Yao, X Yan. Uterine contractility in intrahepatic cholestasis of pregnancy. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology. vol 34. issue 3. 2015-04-13. PMID:24484433. |
aspartate transaminase (ast) appeared to correlate with contraction frequency (r = 0.357, p = 0.006) and montevideo units (mvus) (r = 0.349, p = 0.007). |
2015-04-13 |
2023-08-12 |
Not clear |
| Tao Liang, Xiaoyu Chen, Min Su, Hongqiu Chen, Guozhe Lu, Kun Lian. Vitamin C exerts beneficial hepatoprotection against Concanavalin A-induced immunological hepatic injury in mice through inhibition of NF-κB signal pathway. Food & function. vol 5. issue 9. 2015-04-13. PMID:25030772. |
interestingly, vc administration significantly reduced serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast) and total-bilirubin (t-bilirubin) in con a-lesioned mice, while serum concentrations of albumin and total-protein (t-protein) were increased. |
2015-04-13 |
2023-08-13 |
mouse |
| Xin Zhang, Zufang Wu, Peifang Wen. Antioxidant and hepatoprotective effect of (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3″Me) from Chinese oolong tea. Journal of agricultural and food chemistry. vol 62. issue 41. 2015-04-13. PMID:25259858. |
for hepatoprotective activity in vivo, the administration of egcg3″me at a dose of 100 mg/kg bw per day significantly decreased the serum levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) from 64.6 ± 3.17 and 97.6 ± 3.78 to 39.6 ± 2.72 and 59.6 ± 3.02 u/l, decreased the liver level of malondialdehyde (mda) from 1.14 ± 0.08 to 0.77 ± 0.03 nmol/mg protein, and remarkably restored the liver activities of superoxide dismutase (sod) and glutathione peroxidase (gsh-px) from 247 ± 20.1 u/mg and 6.12 ± 0.17 nmol/mg protein to 261 ± 9.98 u/mg and 8.10 ± 0.03 nmol/mg protein, respectively, in alcohol-induced liver injury mice. |
2015-04-13 |
2023-08-13 |
mouse |
| Canxia He, Baolong Li, Wei Song, Zhongqing Ding, Shuran Wang, Yujuan Sha. Sulforaphane attenuates homocysteine-induced endoplasmic reticulum stress through Nrf-2-driven enzymes in immortalized human hepatocytes. Journal of agricultural and food chemistry. vol 62. issue 30. 2015-04-09. PMID:24970331. |
after human hepatocyte line hhl-5 was preincubated with sfn and subsequently with 10 mmol/l hcy, sfn improved the pathologic changes which are caused by hcy, including cell morphological abnormality, endoplasmic reticulum (er) swelling, excessive generation of reactive oxygen species (ros), the increased malondialdehyde (mda) levels, as well as the increased activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2015-04-09 |
2023-08-13 |
human |
| Hong-Fang Ji, Yan Sun, Liang She. Effect of vitamin E supplementation on aminotransferase levels in patients with NAFLD, NASH, and CHC: results from a meta-analysis. Nutrition (Burbank, Los Angeles County, Calif.). vol 30. issue 9. 2015-04-07. PMID:24976430. |
the aim of this study was to assess the effect of vitamin e supplementation in lowering alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels in patients with nonalcoholic fatty liver disease (nafld), nonalcoholic steatohepatitis (nash), and chronic hepatitis c (chc). |
2015-04-07 |
2023-08-13 |
Not clear |
| Erqun Song, Xiaomin Xia, Chuanyang Su, Wenjing Dong, Yaping Xian, Wei Wang, Yang Son. Hepatotoxicity and genotoxicity of patulin in mice, and its modulation by green tea polyphenols administration. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 71. 2015-04-06. PMID:24949943. |
we found that pat-treatment induced serum alanine transaminase (alt) and aspartate transaminase (ast) activities significantly. |
2015-04-06 |
2023-08-13 |
mouse |
| Yuka Sugimoto, Kenji Wakai, Hiroko Nakagawa, Shino Suma, Tae Sasakabe, Tatsuhiko Sakamoto, Naoyuki Takashima, Sadao Suzuki, Shin Ogawa, Keizo Ohnaka, Nagato Kuriyama, Kokichi Arisawa, Haruo Mikami, Michiaki Kubo, Satoyo Hosono, Nobuyuki Hamajima, Hideo Tanak. Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers: a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. Gene. vol 557. issue 2. 2015-04-06. PMID:25523094. |
serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) were measured during a routine health check-up. |
2015-04-06 |
2023-08-13 |
human |
| Satish Kumar, Anjali Amarapurkar, Deepak Amarapurka. Serum aminotransferase levels in healthy population from western India. The Indian journal of medical research. vol 138. issue 6. 2015-04-02. PMID:24521632. |
currently upper limits of normal for aspartate aminotransferase (ast) or alt levels used are based on the western literature. |
2015-04-02 |
2023-08-12 |
Not clear |
| Herwandhani Putri, Standie Nagadi, Yonika Arum Larasati, Nindi Wulandari, Adam Hermawan, Agung Endo Nugroh. Cardioprotective and hepatoprotective effects of Citrus hystrix peels extract on rats model. Asian Pacific journal of tropical biomedicine. vol 3. issue 5. 2015-03-30. PMID:23646300. |
to observe the combination effect of doxorubicin and citrus hystrix (kaffir lime's) peel ethanolic extract (chee) on blood serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activity and cardio-hepato-histopathology of female sprague dawley rats. |
2015-03-30 |
2023-08-12 |
rat |
| Q Pan, Y Yu, Z Tang, M Xi, H Jiang, Y Xun, X Liu, H Liu, J Hu, G Zan. Increased levels of IL-21 responses are associated with the severity of liver injury in patients with chronic active hepatitis B. Journal of viral hepatitis. vol 21. issue 9. 2015-03-30. PMID:24611989. |
the percentages of il-21(+) cd3(+) cd8(-) and il-21(+) cd3(+) cd8(+) t cells and the levels of serum il-21 in cahb patients were significantly higher than that in the ic, chc patients and hc (p < 0.001) and were correlated positively with the levels of serum alanine aminotransferase (alt, r = 0.424, p < 0.001; r = 0.392, p = 0.001) and aspartate aminotransferase (ast, r = 0.388, p = 0.001; r = 0.329, p = 0.005) in cahb patients, respectively. |
2015-03-30 |
2023-08-12 |
Not clear |