| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fardin Asadi, Mehran Mohseni, Karim Dadashi Noshahr, Fariba Haj Soleymani, Ahmad Jalilvand, Azam Heidar. Effect of Molybdenum Nanoparticles on Blood Cells, Liver Enzymes, and Sexual Hormones in Male Rats. Biological trace element research. vol 175. issue 1. 2017-01-19. PMID:27260534. |
the results of liver enzymes showed that serum levels of aspartate aminotransferase (ast) decreased significantly in both dosage groups of 5 and 10 mg/kg bw (mo nps) when compared with the control group (p < 0.05), and significant decrease obtained in lactate dehydrogenase (ldh) levels at dose of 5 mg/kg bw in comparison with the control group (p < 0.05). |
2017-01-19 |
2023-08-13 |
human |
| Muhammad Jahangir Hossen, Mi-Yeon Kim, Jae Youl Ch. MAPK/AP-1-Targeted Anti-Inflammatory Activities of Xanthium strumarium. The American journal of Chinese medicine. vol 44. issue 6. 2017-01-19. PMID:27627914. |
additionally, these results highlighted the hepatoprotective and curative effects of xs-me in a mouse model of lps/d-galn-induced acute liver injury, as assessed by elevated serum levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt), and histological damage. |
2017-01-19 |
2023-08-13 |
mouse |
| Liying Tang, Fengli Yang, Zhirui Fang, Chengmu H. Resveratrol Ameliorates Alcoholic Fatty Liver by Inducing Autophagy. The American journal of Chinese medicine. vol 44. issue 6. 2017-01-19. PMID:27627919. |
the results showed that res (30[formula: see text]mg/kg and 100[formula: see text]mg/kg) treatment significantly attenuated hepatic steatosis and lowered the activities of serum alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), low density lipoprotein cholesterol (ldl-c). |
2017-01-19 |
2023-08-13 |
mouse |
| Khalil Al-Ali, Hala Salah Abdel Fatah, Yaser Abdel-Moemen El-Badr. Dual Effect of Curcumin-Zinc Complex in Controlling Diabetes Mellitus in Experimentally Induced Diabetic Rats. Biological & pharmaceutical bulletin. vol 39. issue 11. 2017-01-19. PMID:27803448. |
also, the reduced activities of serum aspartate aminotransferase (ast), alanine aminotransferase (alt), urea, and creatinine in the diabetic rats treated with the complex exhibited the non-toxic nature of the curcumin-zn complex. |
2017-01-19 |
2023-08-13 |
rat |
| Xiaochuan Zhang, Lili Jin, Zhe Cui, Changhao Zhang, Xue Wu, Hyun Park, Hongmei Quan, Chunmei Ji. Antiparasitic effects of oxymatrine and matrine against Toxoplasma gondii in vitro and in vivo. Experimental parasitology. vol 165. 2017-01-18. PMID:26993085. |
viscera indexes and liver biochemical parameters, such as alanine aminotransferase (alt), aspartate aminotransferase (ast), glutathione (gsh) and malondialdehyde (mda), were examined to evaluate the toxicity of compounds to mice. |
2017-01-18 |
2023-08-13 |
mouse |
| Yu Wu, Xing-chao Geng, Ju-feng Wang, Yu-fa Miao, Yan-li Lu, Bo L. The HepaRG cell line, a superior in vitro model to L-02, HepG2 and hiHeps cell lines for assessing drug-induced liver injury. Cell biology and toxicology. vol 32. issue 1. 2017-01-17. PMID:27027780. |
in addition, aspartate aminotransferase (ast), lactate dehydrogenase (ldh), and malate dehydrogenase (mdh) all correlated with the cytotoxic effects of diclofenac sodium (p < 0.05), buspirone hydrochloride (p < 0.01), and danazol (p < 0.01) in the heparg cell line. |
2017-01-17 |
2023-08-13 |
Not clear |
| Qi Cai Chen, Juan Xiao, Peng Peng Zhang, Li Li Chen, Xiao Xiao Chen, Shu Mei Wan. Longitudinal Changes in Liver Aminotransferases Predict Metabolic Syndrome in Chinese Patients with Nonviral Hepatitis. Biomedical and environmental sciences : BES. vol 29. issue 4. 2017-01-17. PMID:27241736. |
this study explored the correlation of longitudinal changes in serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels with the incidence of metabolic syndrome (mets) based on a dynamic health examination cohort. |
2017-01-17 |
2023-08-13 |
Not clear |
| Mohammad Reza Sepand, Kamal Razavi-Azarkhiavi, Ameneh Omidi, Mohammad Reza Zirak, Samin Sabzevari, Ali Reza Kazemi, Omid Sabzevar. Effect of Acetyl-L-Carnitine on Antioxidant Status, Lipid Peroxidation, and Oxidative Damage of Arsenic in Rat. Biological trace element research. vol 171. issue 1. 2017-01-16. PMID:26349760. |
furthermore, naaso2 administration increased serum values of alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), and bilirubin. |
2017-01-16 |
2023-08-13 |
rat |
| Huihui Li, Dapeng Qiu, Qin Gao, Huaxue Wang, Meiqun Su. [Selectively activating melanocortin 4 receptor acts against rat sepsis-induced acute liver injury via HMGB1/TLR4/NF-κB signaling pathway]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 32. issue 8. 2017-01-13. PMID:27412936. |
heart rate (hr), mean arterial pressure (map), aspartate transaminase (ast) and alanine transaminase (alt) were measured 24 hours after operation. |
2017-01-13 |
2023-08-13 |
rat |
| Sundararaj Rubila, Thottiam Vasudevan Ranganathan, Kunnathur Murugesan Sakthive. Protective Effect of Zingiber officinale Against Dalton's Lymphoma Ascites Tumour by Regulating Inflammatory Mediator and Cytokines. Applied biochemistry and biotechnology. vol 180. issue 8. 2017-01-13. PMID:27435276. |
treatment with z. officinale paste showed significant increase in haemoglobin level and decrease in aspartate amino transferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp) and gamma glutamyl transferase (γ-gt) level. |
2017-01-13 |
2023-08-13 |
mouse |
| Chang-Chi Lai, Po-Hsun Huang, An-Han Yang, Shu-Chiung Chiang, Chia-Yu Tang, Kuo-Wei Tseng, Cheng-Hsiung Huan. Baicalein Reduces Liver Injury Induced by Myocardial Ischemia and Reperfusion. The American journal of Chinese medicine. vol 44. issue 3. 2017-01-12. PMID:27109160. |
the induced myocardial i/r significantly increased the serum levels of aspartate transaminase (ast) and alanine transaminase (alt), indicating the presence of liver injury. |
2017-01-12 |
2023-08-13 |
rat |
| Karen Bodié, Wayne R Buck, Julia Pieh, Michael J Liguori, Andreas Pop. Biomarker evaluation of skeletal muscle toxicity following clofibrate administration in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 68. issue 5. 2017-01-11. PMID:27020044. |
the standard clinical pathology assays aspartate aminotransferase (ast), alanine aminotransferase (alt), and creatine kinase (ck) enzyme activity were compared to novel biomarkers fatty acid binding protein 3 (fabp3), myosin light chain 3 (myl3), muscular isoform of ck immunoreactivity (three isoforms ckbb, ckmm, ckmb), parvalbumin (prv), skeletal troponin i (stni), cardiac troponin t (ctnt), cardiac troponin i (ctni), ckmm, and myoglobin (myo). |
2017-01-11 |
2023-08-13 |
rat |
| Don C Rockey, Alan Elliott, Thomas Lyle. Prediction of esophageal varices and variceal hemorrhage in patients with acute upper gastrointestinal bleeding. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. vol 64. issue 3. 2017-01-09. PMID:26912006. |
this retrospective study of a large cohort of patients with ugib used logistic regression analyses to evaluate the platelet count, aspartate aminotransferase (ast) to platelet ratio index (apri), ast to alanine aminotransferase (alt) ratio (aar) and lok index (all non-invasive blood markers) as predictors of variceal bleeding in (1) all patients with ugib and (2) patients with cirrhosis and ugib. |
2017-01-09 |
2023-08-13 |
Not clear |
| Elżbieta Paszynska, Nadine Schlueter, Agnieszka Slopien, Monika Dmitrzak-Weglarz, Marta Dyszkiewicz-Konwinska, Christian Hanni. Salivary enzyme activity in anorexic persons—a controlled clinical trial. Clinical oral investigations. vol 19. issue 8. 2017-01-06. PMID:25753979. |
the aim of the clinical trial was to evaluate stimulated and resting salivary flow rate and the activity of the following enzymes in both types of saliva: amylase, aspartate amino transferase (ast), alanine amino transferase (alt), collagenase, lysozyme, peroxidase, serine and acidic proteases, and trypsin in persons with anorexia nervosa (an) and to compare them with those of healthy controls. |
2017-01-06 |
2023-08-13 |
Not clear |
| Camila R Murussi, Maiara D Costa, Jossiele W Leitemperger, Luciana Guerra, Cintia C R Rodrigues, Charlene C Menezes, Eduardo S Severo, Fábio Flores-Lopes, Joseânia Salbego, Vania L Lor. Exposure to different glyphosate formulations on the oxidative and histological status of Rhamdia quelen. Fish physiology and biochemistry. vol 42. issue 2. 2017-01-06. PMID:26508170. |
silver catfish (rhamdia quelen) were exposed to three different commercial formulations of gly 48% (orium(®), original(®) and biocarb(®)) at 0.0, 2.5 and 5.0 mg/l for 96 h. the effects in thiobarbituric acid-reactive substances (tbars), catalase (cat), superoxide dismutase (sod), glutathione-s-transferase (gst) and histological alterations were analysed in the liver, whereas alanine aminotransferase (alt) and aspartate aminotransferase (ast) were studied in the plasma. |
2017-01-06 |
2023-08-13 |
cat |
| O Naseer, J A Khan, M S Khan, M O Omer, G A Chishti, M L Sohail, M U Salee. Comparative Efficacy of Silymarin and Choline Chloride (Liver Tonics) in Preventing the Effects of Aflatoxin B1 in Bovine Calves. Polish journal of veterinary sciences. vol 19. issue 3. 2017-01-06. PMID:27760040. |
serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), blood urea nitrogen (bun) and creatinine significantly increased due to afb1. |
2017-01-06 |
2023-08-13 |
cattle |
| Yang Lu, DongMei Hu, ShanBo Ma, Xian Zhao, Shan Wang, Guo Wei, XiFang Wang, AiDong Wen, JingWen Wan. Protective effect of wedelolactone against CCl4-induced acute liver injury in mice. International immunopharmacology. vol 34. 2016-12-30. PMID:26921731. |
our data showed that wel markedly decreased the ccl4-induced elevation of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, and improved hepatic histopathology changes. |
2016-12-30 |
2023-08-13 |
mouse |
| Ming Shu, Xiao-Rong Hu, Zuo-An Hung, Dam-Dan Huang, Shun Zhan. Effects of tanshinone IIA on fibrosis in a rat model of cirrhosis through heme oxygenase-1, inflammation, oxidative stress and apoptosis. Molecular medicine reports. vol 13. issue 4. 2016-12-30. PMID:26936326. |
in the cirrhotic rats, the extent of fibrosis, levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast), heme oxygenase‑1 (ho‑1) protein expression, serum levels of nuclear factor (nf)‑κb, tumor necrosis factor‑α (tnf‑α), interleukin (il)‑1β and il‑6, superoxide dismutase (sod), catalase (cat) and glutathione peroxidase (gsh‑px), and the protein expression levels of phosphorylated‑p38 mitogen‑activated protein kinase (mapk) were all significantly increased. |
2016-12-30 |
2023-08-13 |
rat |
| Qingqing Dong, Fei Chu, Chengzhu Wu, Qiang Huo, Huaiyong Gan, Xiaoming Li, Hao Li. Scutellaria baicalensis Georgi extract protects against alcohol‑induced acute liver injury in mice and affects the mechanism of ER stress. Molecular medicine reports. vol 13. issue 4. 2016-12-30. PMID:26936686. |
the protective effect was investigated by measuring the levels of aspartate transaminase (ast), alanine transferase (alt) and triglyceride (tg) in the serum, and the levels of glutathione (gsh) and malondialdehyde (mda) in liver tissues. |
2016-12-30 |
2023-08-13 |
mouse |
| Yao Tong, Xi-Bing Ding, Zhi-Xia Chen, Shu-Qing Jin, Xiang Zhao, Xin Wang, Shu-Ya Mei, Xi Jiang, Lingyu Wang, Quan L. WISP1 mediates hepatic warm ischemia reperfusion injury via TLR4 signaling in mice. Scientific reports. vol 6. 2016-12-29. PMID:26821752. |
anti-wisp1 antibody significantly decreased serum alanine aminotransferase (alt), aspartate aminotransferase (ast), pathological changes and pro-inflammatory cytokine levels in the mice following i/r. |
2016-12-29 |
2023-08-13 |
mouse |