| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Su-Wen Chen, Guo-Liang Yin, Chao-Yuan Song, De-Cheng Meng, Wen-Fei Yu, Xin Zhang, Ya-Nan Feng, Peng-Peng Liang, Feng-Xia Zhan. [Diosgenin alleviates NAFLD induced by a high-fat diet in rats via mTOR/SREBP-1c/HSP60/MCAD/SCAD signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 19. 2023-12-19. PMID:38114120. |
the levels of triglyceride(tg), total cholesterol(tc), alanine transaminase(alt), and aspartate transaminase(ast) in the serum were determined by the biochemical method. |
2023-12-19 |
2023-12-23 |
rat |
| Cao Dai, Lin Peng, Yanjie Li, Zhendong Li, Da Chen, Fei Wang, Nan Li. Distribution of per- and polyfluoroalkyl substances in blood, serum, and urine of patients with liver cancer and associations with liver function biomarkers. Journal of environmental sciences (China). vol 139. 2023-12-19. PMID:38105065. |
in addition, multiple regression models adjusted for age, gender and bmi found that increased serum perfluorobutane sulfonic acid (pfbs), perfluoroheptane sulfonic acid (pfhps) and perfluorohexylphosphonic acid (pfhxpa) conentrations are correlated with elevated alkaline phosphatase (alp), aspartate aminotransferase (ast), and alpha-fetoprotein (afp) (p < 0.05). |
2023-12-19 |
2023-12-21 |
Not clear |
| Ningning Yao, Qing Hou, Yu Liang, Xin Cao, Bochen Sun, Lijuan Wei, Ruifang Sun, Jianzhong Ca. Serum aspartate aminotransferase, a novel potential biomarker of prognosis in extranodal natural killer/T cell lymphoma, nasal type. Cancer biomarkers : section A of Disease markers. 2023-12-18. PMID:38108343. |
aspartate aminotransferase (ast), an indicator of liver cell damage, was related to the prognosis of certain malignant tumors. |
2023-12-18 |
2023-12-21 |
Not clear |
| Deng-Lai Li, Si-Ying Liu, Rui Zhu, Si-Tong Meng, Yin-Tao Wang, Zhi-Yong Yang, Liang Li, Xiao-Fang Wei, Guo-Jun Shang, Hao-Tong Wang, Zi-Hui Qu, Ya-Nan Quan, Li-Fang W. Potential protective effects of sodium butyrate on glycinin-induced oxidative stress, inflammatory response, and growth inhibition in Cyprinus carpio. Fish physiology and biochemistry. 2023-12-15. PMID:38099983. |
sb (1.50-2.25 g/kg) increased the activities of aspartate aminotransferase (ast) and alanine aminotransferase (alt) in the hepatopancreas and reduced the activities of ast and alt in the serum. |
2023-12-15 |
2023-12-17 |
cat |
| Fahimeh Chekneh, Hamideh Ghodrati Azadi, Hasan Baghshani, Zahra Moosav. The Hepatorenal Protective Potential of Caffeic Acid Consumption on the Arsenic-Exposed Syrian Mice. Biological trace element research. 2023-12-15. PMID:38102533. |
arsenic administration significantly increased aspartate aminotransferase (ast), alanine aminotransferase (alt), ldh, urea, and creatinine concentrations (p < 0.05). |
2023-12-15 |
2023-12-18 |
mouse |
| Hao Niu, Pablo Solis-Muñoz, Miren García-Cortés, Judith Sanabria-Cabrera, Mercedes Robles-Diaz, Rocío Romero-Flores, Elvira Bonilla-Toyos, Aida Ortega-Alonso, José M Pinazo-Bandera, María R Cabello, Fernando Bessone, Nelia Hernandez, M Isabel Lucena, Raúl J Andrade, Inmaculada Medina-Caliz, Ismael Alvarez-Alvare. Prior drug allergies are associated with worse outcome in patients with idiosyncratic drug-induced liver injury: A machine learning approach for risk stratification. Pharmacological research. vol 199. 2023-12-14. PMID:38072217. |
patients with pda were older (p = 0.009), had higher aspartate aminotransferase (ast) levels (p = 0.047), lower platelet count (p = 0.011) and higher liver-related mortality than those without a history of drug allergies (11% vs. 1.6%, p < 0.001). |
2023-12-14 |
2023-12-17 |
Not clear |
| Mohamed E Abd El-Hack, Mohamed F AboElMaati, Wafaa F Abusudah, Ohaad F Awlya, Najlaa H Almohmadi, Walid Fouad, Hanan S Mohamed, Islam M Youssef, Naif A Al-Gabri, Sarah I Othman, Ahmed A Allam, Ayman E Taha, Guillermo Tellez-Isaias, Amira M Mansou. Consequences of dietary cinnamon and ginger oils supplementation on blood biochemical parameters, oxidative status, and tissue histomorphology of growing Japanese quails. Poultry science. vol 103. issue 2. 2023-12-14. PMID:38096669. |
results showed that adding herbal oils significantly (p < 0.05) decreased the aspartate aminotransferase (ast) and urea levels compared to control and colistin groups. |
2023-12-14 |
2023-12-17 |
Not clear |
| Long Liu, Na Yang, Yueji Chen, Zhihao Xu, Qingwei Zhang, Xiuxiu Miao, Yanan Zhao, Geng Hu, Liying Liu, Zhi Song, Xianyao L. Effects of fulvic acid on broiler performance, blood biochemistry, and intestinal microflora. Poultry science. vol 103. issue 2. 2023-12-14. PMID:38096671. |
fua supplement significantly improved aspartate aminotransferase (ast) activity in the group iii on d 35 (p < 0.05) and the serum levels of iga and igg on d 21 and d 35 (p < 0.05), but reduced glutathione peroxidase (gsh-px) level on d 21 (p < 0.05) and malondialdehyde (mda) level in serum on d 35 (p < 0.05). |
2023-12-14 |
2023-12-17 |
Not clear |
| Yuansong Zhuang, Quanxu An, Fuhang Wang, Dongjian Han, Zhentao Qiao, Qingjiao Jiang, Miaomiao Liu, Yuhang Li, Jiahong Shangguan, Xuanye Bi, Deliang She. The role of circulating biomarkers in predicting the 30-day mortality of immune checkpoint inhibitors-related myocarditis: a retrospective cohort study. Internal and emergency medicine. 2023-12-12. PMID:38085435. |
after adjusting for potential confounding factors using multivariate analysis tools, we demonstrated the excellent performance of biomarkers in predicting 30-day mortality in patients with icis-m, including plt (hazard ratio (hr), 1.07; 95% confidence interval (95%ci), 1.01-1.14; p = 0.028), alt (hr, 1.23; 95%ci, 1.06-1.41; p = 0.005), ast(hr, 1.06; 95%ci, 1.01-1.10; p = 0.015), ldh (hr, 1.15; 95%ci, 1.04-1.26; p = 0.004), troponin i(hr, 1.44; 95%ci, 1.09-1.89; p = 0.009), plr (blood plate/lymphocyte) (hr, 1.04; 95% ci, 1.01-1.07; p = 0.024), lar (lactate dehydrogenase/albumin) (hr, 1.05; 95%ci, 1.01-1.09; p = 0.012), and aar (aspartate transaminase/albumin) (hr, 1.18; 95%ci, 1.00-1.39; p = 0.048). |
2023-12-12 |
2023-12-17 |
Not clear |
| Alaa Elmetwalli, Neamat H Kamosh, Rania El Safty, Amany I Youssef, Mohammed M Salama, Khaled M Abd El-Razek, Tarek El-Sewed. Novel phloretin-based combinations targeting glucose metabolism in hepatocellular carcinoma through GLUT2/PEPCK axis of action: in silico molecular modelling and in vivo studies. Medical oncology (Northwood, London, England). vol 41. issue 1. 2023-12-11. PMID:38078989. |
we have measured the expression of the glucose transporter 2 (glut2), phosphoenolpyruvate carboxykinases (pepck), caspase-3, beclin 1, cyclin d1, and cytokeratin 18 genes; blood glucose and atp levels; alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities. |
2023-12-11 |
2023-12-17 |
mouse |
| Ebrahim Salimi-Sabour, Ramazan-Ali Tahri, Amirhossein Asgari, Maryam Ghorban. The novel hepatoprotective effects of silibinin-loaded nanostructured lipid carriers against diazinon-induced liver injuries in male mice. Pesticide biochemistry and physiology. vol 197. 2023-12-10. PMID:38072518. |
alanine (alt) and aspartate (ast) aminotransferase levels, oxidative stress biomarkers, inflammatory cytokines, and histopathological alterations were assessed. |
2023-12-10 |
2023-12-17 |
mouse |
| Yutong Yuan, Xinyi Wang, Yumeng Wang, Yaqi Liu, Liang Zhao, Lei Zhao, Shengbao Ca. The Gastroprotective Effect of Walnut Peptides: Mechanisms and Impact on Ethanol-Induced Acute Gastric Mucosal Injury in Mice. Nutrients. vol 15. issue 23. 2023-12-09. PMID:38068724. |
walnut peptides significantly inhibited the excessive accumulation of alanine aminotransferase (alt), aspartate transferase (ast), and malondialdehyde (mda), while promoting the expression of reduced glutathione (gsh), total antioxidant capacity (t-aoc), glutathione disulfide (gssg), and mouse epidermal growth factor (egf). |
2023-12-09 |
2023-12-17 |
mouse |
| Elham Kalantari, Naime Majidi Zolbanin, Morteza Ghasemnejad-Berenj. Protective effects of empagliflozin on methotrexate induced hepatotoxicity in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 170. 2023-12-08. PMID:38064971. |
furthermore, the levels of tissue malondialdehyde (mda) and activity of anti-oxidative enzymes, superoxide dismutase (sod), glutathione peroxidase (gpx), and catalase, as well as serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were evaluated. |
2023-12-08 |
2023-12-17 |
rat |
| Longsheng Hong, Zongyi Sun, Danning Xu, Wanyan Li, Nan Cao, Xinliang Fu, Yunmao Huang, Yunbo Tian, Bingxin L. Transcriptome and lipidome integration unveils mechanisms of fatty liver formation in Shitou geese. Poultry science. vol 103. issue 2. 2023-12-02. PMID:38042038. |
however, no significant differences were observed in the levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast), which are common indicators of liver damage. |
2023-12-02 |
2023-12-10 |
Not clear |
| Jake Darbhanga, Kiarra Krulikowski, Suzanne I Riski. Emerging Diagnostics and Therapeutics for Non-alcoholic Fatty Liver Disease. Cureus. vol 15. issue 10. 2023-12-01. PMID:38021846. |
disease identification can be done invasively with a liver biopsy or noninvasively through elastography and measurements of biomarkers, such as the alanine aminotransferase (alt) and aspartate aminotransferase (ast) liver enzymes. |
2023-12-01 |
2023-12-07 |
human |
| Faizan Zahoor, Najam-Us-Sehar Saeed, Salman Javed, Hafiz Zeeshan Sadiq, Fasih Mand Khan, Miqdad Haider, Muhammad Nabeel Shafqat, Arman Maqbool, Auj Chaudhr. Association of Metabolic Dysfunction-Associated Steatotic Liver Disease/Non-alcoholic Fatty Liver Disease With Type 2 Diabetes Mellitus: A Case-Control Study in a Tertiary Care Hospital in Pakistan. Cureus. vol 15. issue 10. 2023-12-01. PMID:38021965. |
all participants were assessed for serum aspartate transaminase (ast) and alanine transaminase (alt) levels and underwent abdominal ultrasound to determine hepatic fibrosis. |
2023-12-01 |
2023-12-07 |
human |
| Xiangbing Cheng, Fangcheng Li, Gilbert Kumilamba, Jiayi Liao, Jiangwei Cao, Jiamin Sun, Qigen Li. Transcriptome analysis in hepatopancreases reveals the response of domesticated common carp to a high-temperature environment in the agricultural heritage rice-fish system. Frontiers in physiology. vol 14. 2023-12-01. PMID:38028756. |
compared with the control group, the serum levels of malondialdehyde (mda), glucose (glu), glutathione peroxidase (gsh-px), catalase (cat), alanine aminotransferase (alt), and aspartate aminotransferase (ast) show no significant change. |
2023-12-01 |
2023-12-10 |
cat |
| Jingxin Ouyang, Qiufen Li, Hua Zhou, Guiyao Li, Yajing Wu, Lei Yang, Guanhong L. Tryptophan alleviates chronic heat stress-induced impairment of antioxidant capacities, inflammatory response, and mitochondrial function in broilers. Tropical animal health and production. vol 55. issue 6. 2023-12-01. PMID:38030895. |
however, dietary supplementation with 0.18% trp enhanced serum tp content, glutathione peroxidase (gsh-px), sod, catalase (cat) activities, and t-aoc; decreased aspartate aminotransferase (ast) activities (p < 0.05); and lowered serum il-1β, il-6, il-18 contents (p < 0.05). |
2023-12-01 |
2023-12-10 |
cat |
| Yoko Kitano, Yusuke Kohri, Tsutomu Id. [A Patient with Endometrial Cancer Safely Administered Pembrolizumab Through a Pharmaceutical Outpatient Service]. Gan to kagaku ryoho. Cancer & chemotherapy. vol 50. issue 10. 2023-11-30. PMID:38035842. |
after cycle 1, which was administered during hospitalization, grade 2 increases in aspartate aminotransferase(ast)and alanine aminotransferase(alt)were observed. |
2023-11-30 |
2023-12-10 |
Not clear |
| Hao Hao, Youmei Xu, Rui Chen, Shanshan Qi, Xiang Liu, Beibei Lin, Xiaohua Chen, Xiaoying Zhang, Lijuan Yue, Chen Che. Protective effects of chlorogenic acid against cyclophosphamide induced liver injury in mice. Biotechnic & histochemistry : official publication of the Biological Stain Commission. 2023-11-29. PMID:38018995. |
we measured aminotransferase alanine transaminase (alt) and aspartate transaminase (ast) levels in the serum. |
2023-11-29 |
2023-12-07 |
mouse |