| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Napierala, Jan Olszewski, Izabela Miechowicz, Anna Jablecka, Agata Czarnywojtek, Stanislaw Malinger, Ewa Flore. The influence of tobacco smoke exposure on selected markers of oxidative stress, kidneys and liver function in the serum of rats with streptozotocin-induced diabetes. Pharmacological reports : PR. vol 71. issue 6. 2020-04-27. PMID:31698285. |
the objective of the study was to examine the effects of tobacco smoke on the serum concentrations of relevant oxidative stress markers such as total protein (tp), reduced glutathione (gsh), glutathione s-transferase (gst) and thiobarbituric acid reactive substances (tbars), as well as renal (creatinine, urea) and liver function (alkaline phosphatase, alp; alanine aminotransferase, alt; aspartate aminotransferase, ast) among animals with induced diabetes after administration of a single dose of streptozotocin (65 mg/kg, ip). |
2020-04-27 |
2023-08-13 |
rat |
| Zhengxuan Wang, Mingcai Liang, Hui Li, Liang Cai, Lin Yan. Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway. International journal of molecular sciences. vol 20. issue 24. 2020-04-27. PMID:31817701. |
compared with casein, rp reduced hepatic accumulations of reactive oxygen species (ros) and nitro oxide (no), and plasma activities of alanine transaminase (alt) and aspartate transaminase (ast) in growing and adult rats. |
2020-04-27 |
2023-08-13 |
rat |
| Tingting Gong, Wenbo Jiang, Zhijian Gao, Yingying Chen, Shuying Ga. Dibromoacetic Acid Induced Hepatotoxicity in Mice through Oxidative Stress and Toll-Like Receptor 4 Signaling Pathway Activation. Oxidative medicine and cellular longevity. vol 2019. 2020-04-27. PMID:31827682. |
in this study, we found that dba could induce obvious hepatotoxcity in balb/c mice as indicated by histological changes, increasing serum level of alanine aminotransferase (alt) and aspartate aminotransferase (ast), and accumulation of hepatic glycogen, after the mice were administered dba at doses of 1.25, 5, and 20 mg/kg body weight for 28 days via oral gavage. |
2020-04-27 |
2023-08-13 |
mouse |
| Kendra A Young, Nicholette D Palmer, Tasha E Fingerlin, Carl D Langefeld, Jill M Norris, Nan Wang, Anny H Xiang, Xiuqing Guo, Adrienne H Williams, Yii-Der I Chen, Kent D Taylor, Jerome I Rotter, Leslie J Raffel, Mark O Goodarzi, Richard M Watanabe, Lynne E Wagenknech. Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium. Obesity (Silver Spring, Md.). vol 27. issue 8. 2020-04-24. PMID:31219225. |
the objective of this study was to determine whether loci in known and novel genes were associated with variation in aspartate aminotransferase (ast) (n = 3,644), alanine aminotransferase (alt) (n = 3,595), and gamma-glutamyl transferase (ggt) (n = 1,577) levels by conducting the first genome-wide association study (gwas) of liver enzymes, which commonly measure liver function, in individuals of mexican american ancestry. |
2020-04-24 |
2023-08-13 |
Not clear |
| Mohsen Mazidi, Niki Katsiki, Maciej Banac. A higher flavonoid intake is associated with less likelihood of nonalcoholic fatty liver disease: results from a multiethnic study. The Journal of nutritional biochemistry. vol 65. 2020-04-20. PMID:30623852. |
fatty liver index (fli) and serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) were significantly higher in the first tertile (t1) of flavonoid intake compared with the highest tertile (t3: with the highest flavonoid intake) (fli: 67.1 vs. 36.2, ast: 31.2 vs 26.8 u/l and, alt: 34.2 vs. 24.2 u/l, respectively; p<.001 for all comparisons). |
2020-04-20 |
2023-08-13 |
human |
| Zhihai Shi, Huijie Xing, Chunli Qi, Meixia Fang, Jiangnan Fu, Xingwang Zhan. Chinese tree shrews as a primate experimental animal eligible for the study of alcoholic liver disease: characterization and confirmation by MRI. Experimental animals. vol 69. issue 1. 2020-04-20. PMID:31554748. |
blood alanine aminotransferase (alt), aspartate aminotransferase (ast), alcohol, and liver malondialdehyde (mda) concentrations were determined, and the histopathology of the liver was checked by hematoxylin & eosin (he) and oil red o staining on day 0 and on the 4th, 7th and 14th days after alcohol feeding. |
2020-04-20 |
2023-08-13 |
human |
| W Xie, Y Deng, S Chen, Q Yan. Association between eosinophil count and cholelithiasis among a population with Journal of helminthology. vol 94. 2020-04-17. PMID:31779732. |
significant differences were found among various eosinophil count quartiles for c. sinensis infection, body mass index (bmi), systolic blood pressure (sbp), diastolic blood pressure (dbp), alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), γ-glutamyltranspeptidase (γ-gt), triglyceride (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), creatinine (cre), blood urea nitrogen (bun), uric acid (ua) and non-alcoholic fatty liver disease (nafld) (all p < 0.001). |
2020-04-17 |
2023-08-13 |
human |
| Muhammad Shoaib Alam, Xu-Fang Liang, Liwei Liu, Shan He, Yulan Kuang, Seyed Hossein Hoseinifar, Farman Ullah Dawa. Growth and Metabolic Response of Chinese Perch to Different Dietary Protein-to-Energy Ratios in Artificial Diets. International journal of molecular sciences. vol 20. issue 23. 2020-04-14. PMID:31795078. |
the activities of nitrogen metabolism-related enzymes (alanine aminotransferase (alt), aspartate aminotransferase (ast) glutamate dehydrogenase (gdh), and adenosine 5'-monophosphate deaminase (ampd)) as well as the mrna expression of the |
2020-04-14 |
2023-08-13 |
Not clear |
| Jian-Qiao Li, Wen-Feng Huang, Hai-Bo He, Dong-Xiao Zhao, Jian-Zhong Hu, Shun-Guang Lu, Jia-Xin Ye, Kun Zo. [Study on protective effect of water extract from Sabia parviflora on liver injury in mice induced by acetaminophen]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 6. 2020-04-14. PMID:32281358. |
the blood was collected from the abdominal aorta and centrifuged to obtain the serum for detecting aspartate aminotransferase(ast) activity and alanine aminotransferase(alt) activity. |
2020-04-14 |
2023-08-13 |
mouse |
| Kyeong Seok Kim, Na Yoon Kim, Ji Yeon Son, Jae Hyeon Park, Su Hyun Lee, Hae Ri Kim, Boomin Kim, Yoon Gyoon Kim, Hye Gwang Jeong, Byung Mu Lee, Hyung Sik Ki. Curcumin Ameliorates Benzo[a]pyrene-Induced DNA Damages in Stomach Tissues of Sprague-Dawley Rats. International journal of molecular sciences. vol 20. issue 22. 2020-04-13. PMID:31698770. |
we observed that aspartate aminotransferase (ast), alanine aminotransferase (alt), and glucose levels were significantly reduced in rats treated with high dose co-administration of curcumin (200 mg/kg) compared to bap alone. |
2020-04-13 |
2023-08-13 |
rat |
| Xiaoting Ge, Zhenfang Liu, Qingzhi Hou, Lulu Huang, Yanting Zhou, Defu Li, Sifang Huang, Xiaoyu Luo, Yingnan Lv, Longman Li, Hong Cheng, Xiang Chen, Gaohui Zan, Yanli Tan, Chaoqun Liu, Yunfeng Zou, Xiaobo Yan. Plasma metals and serum bilirubin levels in workers from manganese-exposed workers healthy cohort (MEWHC). Environmental pollution (Barking, Essex : 1987). vol 258. 2020-04-09. PMID:31838386. |
for 571 on-the-spot workers in the manganese-exposed workers healthy cohort (mewhc), we determined liver function parameters: total bilirubin (tbili), direct bilirubin (dbili), indirect bilirubin (ibili), alanine transaminase (alt) and aspartate transaminase (ast). |
2020-04-09 |
2023-08-13 |
Not clear |
| Valéria Regina Cavalcante Dos Santos, Dina Antunes, Dilma do Socorro Moraes de Souza, Otacilio Cruz Moreira, Igor Campos de Almeida Lima, Désio A Farias-de-Oliveira, João Pedro Lobo, Ernesto de Meis, José Rodrigues Coura, Wilson Savino, Angela Cristina Verissimo Junqueira, Juliana de Mei. Human acute Chagas disease: changes in factor VII, activated protein C and hepatic enzymes from patients of oral outbreaks in Pará State (Brazilian Amazon). Memorias do Instituto Oswaldo Cruz. vol 115. 2020-04-09. PMID:32130371. |
the hepatic enzymes alanine aminotransferase (alt) and aspartate aminotransferase (ast) of 30 acd patients were higher compared with controls, and this increase was independent of the treatment with benznidazole. |
2020-04-09 |
2023-08-13 |
human |
| F Echeverría, R Valenzuela, A Espinosa, A Bustamante, D Álvarez, D Gonzalez-Mañan, M Ortiz, S A Soto-Alarcon, L A Videl. Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1/2 and RvD1/2. The Journal of nutritional biochemistry. vol 63. 2020-04-06. PMID:30321750. |
measurements include liver levels of epa, dha and palmitate (gas chromatography), liver resolvins and triglyceride (tg) and serum aspartate transaminase (ast) (specific kits) and hepatic and serum inflammatory markers (quantitative polymerase chain reaction and enzyme-linked immunosorbent assay). |
2020-04-06 |
2023-08-13 |
mouse |
| Yaru Li, Jing Wang, Xu Han, Hua Hu, Fei Wang, Caizheng Yu, Jing Yuan, Ping Yao, Xiulou Li, Kun Yang, Xiaoping Miao, Sheng Wei, Youjie Wang, Weihong Chen, Yuan Liang, Xiaomin Zhang, Huan Guo, Handong Yang, Tangchun Wu, Meian H. Serum alanine transaminase levels predict type 2 diabetes risk among a middle-aged and elderly Chinese population. Annals of hepatology. vol 18. issue 2. 2020-04-06. PMID:31040092. |
it is indicated that high levels of serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) are associated with increased incident type 2 diabetes risk. |
2020-04-06 |
2023-08-13 |
Not clear |
| Habibullah Aktas, Goksen Ertugrul, Muharrem Parlak, Mehmet Una. Long-term isotretinoin use does not cause parenchymal liver change: Ultrasonographic study in 50 patients. Dermatologic therapy. vol 32. issue 5. 2020-04-06. PMID:31241229. |
we examined ultrasonographic findings of the liver together with serum alanin aminotransferase (alt), aspartate aminotransferase (ast), and total cholesterol and triglyceride levels in 50 consecutive patients who have taken isotretinoin 10-40 mg daily for at least 6 months between january and december 2017. |
2020-04-06 |
2023-08-13 |
Not clear |
| Marwa I Ezzat, Mona M Okba, Sherif H Ahmed, Hossny A El-Banna, Abdelbary Prince, Shanaz O Mohamed, Shahira M Ezza. In-depth hepatoprotective mechanistic study of Phyllanthus niruri: In vitro and in vivo studies and its chemical characterization. PloS one. vol 15. issue 1. 2020-04-06. PMID:31940365. |
pretreatment of clone-9 and hepg2 with different concentrations of ae (1, 0.1, 0.01 mg/ml) had significantly reduced the levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) against ccl4 injures, and restored the activity of the natural antioxidants; glutathione (gsh) and superoxide dismutase (sod) towards normalization. |
2020-04-06 |
2023-08-13 |
rat |
| Yaping Liu, Xiaoqian Liu, Ying Wang, Cao Yi, Jiahui Tian, Kechun Liu, Jie Ch. Protective effect of lactobacillus plantarum on alcoholic liver injury and regulating of keap-Nrf2-ARE signaling pathway in zebrafish larvae. PloS one. vol 14. issue 9. 2020-04-02. PMID:31509586. |
then with the treatment of lactobacillus plantarum after 48h, activities of alanine transaminase (alt), aspartate transaminase (ast), superoxide dismutase (sod) and malondialdehyde (mda) in zebrafish tissue homogenate were respectively determined. |
2020-04-02 |
2023-08-13 |
cat |
| Ashraf Al-Brakat. Protective effect of aged garlic extracts against hepatotoxicity induced by ethephon in Wistar albino rat. Environmental science and pollution research international. vol 27. issue 6. 2020-04-02. PMID:31865585. |
in addition, ethephon produced a significant decrease in levels of aspartate transaminase (ast) and alanine transaminase (alt) with a decrease in albumin level. |
2020-04-02 |
2023-08-13 |
rat |
| Gadah AlBasher, Mohamed M Abdel-Daim, Rafa Almeer, Khairy A Ibrahim, Reham Z Hamza, Simona Bungau, Lotfi Aley. Synergistic antioxidant effects of resveratrol and curcumin against fipronil-triggered oxidative damage in male albino rats. Environmental science and pollution research international. vol 27. issue 6. 2020-04-02. PMID:31873888. |
fpn significantly (p < 0.05) elevated the sera of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), lactate dehydrogenase (ldh), γ-glutamyl transferase (ggt), urea, creatinine, and cholesterol levels, whereas serum total protein, albumin, and triglyceride levels were significantly (p < 0.05) decreased, compared to those of the control group. |
2020-04-02 |
2023-08-13 |
rat |
| Enas M Moustafa, Marwa Abdelhameed Mohamed, Noura M Thabe. Gallium Nanoparticle-Mediated Reduction of Brain Specific Serine Protease-4 in an Experimental Metastatic Cancer Model Asian Pacific journal of cancer prevention : APJCP. vol 18. issue 4. 2020-03-31. PMID:28545186. |
liverfunctions (alanine aminotransferase; (alt), aspartate aminotransferase; (ast) and gamma glutamyl transferase;(ggt) and alpha-fetoprotein (afp)) were assessed with histopathological examination of liver sections to confirm theinduction of hcc. |
2020-03-31 |
2023-08-13 |
rat |