| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ahmed Baraka. Revisiting Tramadol: A Multi-Modal Agent for Pain Management. CNS drugs. vol 33. issue 5. 2020-08-28. PMID:31004280. |
tramadol has modulatory effects on several mediators involved in pain signaling, such as voltage-gated sodium ion channels, transient receptor potential v1 channels, glutamate receptors, α |
2020-08-28 |
2023-08-13 |
Not clear |
| I Betina Ip, Uzay E Emir, Andrew J Parker, Jon Campbell, Holly Bridg. Comparison of Neurochemical and BOLD Signal Contrast Response Functions in the Human Visual Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 40. 2020-06-22. PMID:31358655. |
these results suggest that neurochemical concentrations are maintained at lower ranges of contrast levels, which match the statistics of natural vision, and that high stimulus intensity may be critical to increase sensitivity to visually modulated glutamate signals in the early visual cortex using mr spectroscopy. |
2020-06-22 |
2023-08-13 |
human |
| Niansheng Ju, Yang Li, Fang Liu, Hongfei Jiang, Stephen L Macknik, Susana Martinez-Conde, Shiming Tan. Spatiotemporal functional organization of excitatory synaptic inputs onto macaque V1 neurons. Nature communications. vol 11. issue 1. 2020-05-21. PMID:32019929. |
here we perform two-photon dendritic imaging with a genetically-encoded glutamate sensor in awake monkeys, and map the excitatory synaptic inputs on dendrites of individual v1 superficial layer neurons with high spatial and temporal resolution. |
2020-05-21 |
2023-08-13 |
monkey |
| Varun Chokshi, Ming Gao, Bryce D Grier, Ashley Owens, Hui Wang, Paul F Worley, Hey-Kyoung Le. Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling. Neuron. vol 104. issue 4. 2020-03-23. PMID:31563294. |
here, we report that this form of plasticity is specific to intracortical inputs to v1 l2/3 neurons and depends on the activity of nmda receptors (nmdars) and group i metabotropic glutamate receptor 5 (mglur5). |
2020-03-23 |
2023-08-13 |
mouse |
| Yu Man Chan, Kabilan Pitchaimuthu, Qi-Zhu Wu, Olivia L Carter, Gary F Egan, David R Badcock, Allison M McKendric. Relating excitatory and inhibitory neurochemicals to visual perception: A magnetic resonance study of occipital cortex between migraine events. PloS one. vol 14. issue 7. 2020-02-18. PMID:31291247. |
this study compared spectroscopy-measured levels of gaba and glx (glutamine and glutamate complex) in visual cortex between 16 people with migraine and 16 non-headache controls, and assessed whether the concentration of these neurochemicals explains, at least partially, inter-individual variability in binocular rivalry perceptual measures. |
2020-02-18 |
2023-08-13 |
Not clear |
| Katarzyna Kurcyus, Efsun Annac, Nina M Hanning, Ashley D Harris, Georg Oeltzschner, Richard Edden, Valentin Ried. Opposite Dynamics of GABA and Glutamate Levels in the Occipital Cortex during Visual Processing. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 46. 2019-10-10. PMID:30282724. |
in this study, we investigated levels of gaba and glutamate in the visual cortex of healthy human participants (both genders) in three functional states with increasing visual input. |
2019-10-10 |
2023-08-13 |
human |
| Sheng-Tao Yang, Min Wang, Constantinos D Paspalas, Johanna L Crimins, Marcus T Altman, James A Mazer, Amy F T Arnste. Core Differences in Synaptic Signaling Between Primary Visual and Dorsolateral Prefrontal Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 4. 2019-06-26. PMID:29351585. |
the current study compared glutamate and neuromodulatory actions in macaque v1 to those in dlpfc, and found striking regional differences. |
2019-06-26 |
2023-08-13 |
monkey |
| Sheng-Tao Yang, Min Wang, Constantinos D Paspalas, Johanna L Crimins, Marcus T Altman, James A Mazer, Amy F T Arnste. Core Differences in Synaptic Signaling Between Primary Visual and Dorsolateral Prefrontal Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 4. 2019-06-26. PMID:29351585. |
in v1, camp signaling increased neuronal firing, and the phosphodiesterase pde4a was positioned to regulate camp effects on glutamate release from axons. |
2019-06-26 |
2023-08-13 |
monkey |
| Zhi Chen, Tingting Li, Linke Zhang, Huan Wang, Fan H. Bisphenol A exposure remodels cognition of male rats attributable to excitatory alterations in the hippocampus and visual cortex. Toxicology. vol 410. 2019-05-01. PMID:30312744. |
our results showed that male but not female juvenile rats had a marked decline in spatial memory after 0.4 mg/kg/day bpa exposure, which accompanied with downregulation of glutamate receptor (nr2) expression in their hippocampus and primary visual cortex (v1). |
2019-05-01 |
2023-08-13 |
human |
| Zhi Chen, Tingting Li, Linke Zhang, Huan Wang, Fan H. Bisphenol A exposure remodels cognition of male rats attributable to excitatory alterations in the hippocampus and visual cortex. Toxicology. vol 410. 2019-05-01. PMID:30312744. |
importantly, such impairments in the hippocampus of male rats were associated with a decrease of glutamate receptor (nr2) expression in the v1, which could perturb the visual information inputs. |
2019-05-01 |
2023-08-13 |
human |
| Jieyun Shi, Qian Li, Tieqiao We. Dendritic Cell Factor 1-Knockout Results in Visual Deficit Through the GABA System in Mouse Primary Visual Cortex. Neuroscience bulletin. vol 34. issue 3. 2018-09-18. PMID:29430585. |
in this study, we found that loss of dendritic cell factor 1 (dcf1) in the primary visual cortex (v1) caused a sight deficit in mice and induced an abnormal increase in glutamic acid decarboxylase 67, an enzyme that catalyzes the decarboxylation of glutamate to gamma aminobutyric acid and co |
2018-09-18 |
2023-08-13 |
mouse |
| Yue Li, Laijian Wang, Xinxin Zhang, Mengyao Huang, Sitong Li, Xinxing Wang, Lin Chen, Bin Jiang, Yupeng Yan. Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex. Neuropharmacology. vol 128. 2018-07-13. PMID:29031852. |
in adult mouse primary visual cortex, cdk5 formed complex with the gaba synthetic enzyme glutamate decarboxylase gad67, but not with gad65. |
2018-07-13 |
2023-08-13 |
mouse |
| Shuang Li, Xinghua Wang, Junjie Yang, Hao Lei, Xuxia Wang, Yi Xian. Metabolic profile of visual cortex in diabetic rats measured with in vivo proton MRS. NMR in biomedicine. vol 30. issue 11. 2018-06-13. PMID:28915340. |
the results showed that diabetes induced several changes in visual cortex metabolites, such as reduced n-acetylaspartate, glutamate, γ-aminobutyric acid, taurine and choline-containing compound levels. |
2018-06-13 |
2023-08-13 |
rat |
| Christine Wyss, Desmond H Y Tse, Michael Kometer, Jürgen Dammers, Rita Achermann, N Jon Shah, Wolfram Kawohl, Irene Neune. GABA metabolism and its role in gamma-band oscillatory activity during auditory processing: An MRS and EEG study. Human brain mapping. vol 38. issue 8. 2018-04-02. PMID:28480987. |
investigations of the relationship between gaba concentrations, glutamate concentrations, and gamma band activity in humans were mostly restricted to the visual cortex and are conflicting. |
2018-04-02 |
2023-08-13 |
human |
| Wen Zhao, Ai-Ling Bi, Chao-Li Xu, Xiang Ye, Mei-Qing Chen, Xin-Ting Wang, Xiao-Yan Zhang, Jun-Guo Guo, Wen-Jun Jiang, Jin Zhang, Hong-Sheng B. GABA and GABA receptors alterations in the primary visual cortex of concave lens-induced myopic model. Brain research bulletin. vol 130. 2018-02-22. PMID:28163071. |
as the retinal glutamate decarboxylase (gad), gaba, and the mrna levels of gaba receptors increased during the concave lens induced myopia formation, however, whether gaba alterations also occurred in the visual cortex during the concave lens induction is still unknown. |
2018-02-22 |
2023-08-13 |
Not clear |
| Wen Zhao, Ai-Ling Bi, Chao-Li Xu, Xiang Ye, Mei-Qing Chen, Xin-Ting Wang, Xiao-Yan Zhang, Jun-Guo Guo, Wen-Jun Jiang, Jin Zhang, Hong-Sheng B. GABA and GABA receptors alterations in the primary visual cortex of concave lens-induced myopic model. Brain research bulletin. vol 130. 2018-02-22. PMID:28163071. |
in the present study, using hplc, enzyme-linked immunosorbent assay (elisa) and real-time quantitative-pcr (rt-pcr) methods, we observed the changing trends of gaba, glutamate decarboxylase (gad), and gaba receptors in the visual cortex of concave lens-induced myopic guinea pigs. |
2018-02-22 |
2023-08-13 |
Not clear |
| Ursula Staubli, Natalie Rangel-Diaz, Miguel Alcantara, Yong-Xin Li, Jia-Ying Yang, Kai-Ming Zhang, Alan C Foste. Restoration of visual performance by d-serine in models of inner and outer retinal dysfunction assessed using sweep VEP measurements in the conscious rat and rabbit. Vision research. vol 127. 2017-10-20. PMID:27461280. |
the nmda subtype of glutamate receptor and its co-agonist d-serine play a key role in synaptic function in the central nervous system (cns), including visual cortex and retina. |
2017-10-20 |
2023-08-13 |
rat |
| Ronald Zielman, Jannie P Wijnen, Andrew Webb, Gerrit L J Onderwater, Itamar Ronen, Michel D Ferrari, Hermien E Kan, Gisela M Terwindt, Mark C Krui. Cortical glutamate in migraine. Brain : a journal of neurology. vol 140. issue 7. 2017-08-30. PMID:28633367. |
here we assessed glutamate levels and intracellular mobility of glutamate in the visual cortex of migraineurs in-between attacks. |
2017-08-30 |
2023-08-13 |
Not clear |
| Ronald Zielman, Jannie P Wijnen, Andrew Webb, Gerrit L J Onderwater, Itamar Ronen, Michel D Ferrari, Hermien E Kan, Gisela M Terwindt, Mark C Krui. Cortical glutamate in migraine. Brain : a journal of neurology. vol 140. issue 7. 2017-08-30. PMID:28633367. |
the present study suggests that interictal glutamate levels are increased in the visual cortex of migraineurs without aura, supporting the hypothesis of cortical hyperexcitability in migraine. |
2017-08-30 |
2023-08-13 |
Not clear |
| Emily C Turner, Eva K Sawyer, Jon H Kaa. Optic nerve, superior colliculus, visual thalamus, and primary visual cortex of the northern elephant seal (Mirounga angustirostris) and California sea lion (Zalophus californianus). The Journal of comparative neurology. vol 525. issue 9. 2017-08-25. PMID:28188622. |
in order to investigate the architecture of the lateral geniculate nucleus, superior colliculus, and primary visual cortex, we processed brain sections from seal and sea lion pups for nissl substance, cytochrome oxidase, and vesicular glutamate transporters. |
2017-08-25 |
2023-08-13 |
Not clear |