| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideaki Yano, Pramisha Adhikari, Sett Naing, Alexander F Hoffman, Michael H Baumann, Carl R Lupica, Lei Sh. Positive Allosteric Modulation of the 5-HT ACS chemical neuroscience. vol 11. issue 10. 2021-06-18. PMID:32324370. |
positive allosteric modulation of the 5-ht the nonmedical (i.e., recreational) misuse of synthetic cannabinoids (scs) is a worldwide public health problem. |
2021-06-18 |
2023-08-13 |
Not clear |
| b' Nunzia La Maida, Esther Papaseit, Lucia Mart\\xc3\\xadnez, Clara P\\xc3\\xa9rez-Ma\\xc3\\xb1\\xc3\\xa1, Lourdes Poyatos, Manuela Pellegrini, Simona Pichini, Roberta Pacifici, Mireia Ventura, Liliana Galindo, Francesco Paolo Busard\\xc3\\xb2, Mag\\xc3\\xad Farr\\xc3\\xa. Acute Pharmacological Effects and Oral Fluid Biomarkers of the Synthetic Cannabinoid UR-144 and THC in Recreational Users. Biology. vol 10. issue 4. 2021-05-15. PMID:33805054.' |
synthetic cannabinoids (scs) are one of the most frequent classes of new psychoactive substances monitored by the eu early warning system and world health organization. |
2021-05-15 |
2023-08-13 |
human |
| David Fabregat-Safont, María Ibáñez, Abel Baquero, Juan Vicente Sancho, Félix Hernández, Gonzalo Har. Investigation on the consumption of synthetic cannabinoids among teenagers by the analysis of herbal blends and urine samples. Journal of pharmaceutical and biomedical analysis. vol 186. 2021-05-04. PMID:32325401. |
the use of synthetic cannabinoids (scs), which escape conventional detection systems, may be a good alternative to elude routine drug analysis for cannabis. |
2021-05-04 |
2023-08-13 |
Not clear |
| E M Guler, M Y Bektay, A G Akyildiz, B H Sisman, F V Izzettin, A Kocyigi. Investigation of DNA damage, oxidative stress, and inflammation in synthetic cannabinoid users. Human & experimental toxicology. vol 39. issue 11. 2021-04-22. PMID:32508150. |
the widespread use of synthetic cannabinoids (scs) among youth has become an important public health problem. |
2021-04-22 |
2023-08-13 |
Not clear |
| Shiyang Qin, Guobin Xin, Juanna Wei, Genye He, Zengping Yuan, Hua Liu, Xu Zhang, Yuanfeng Wang, Wen Fang Zhang, Jianghai L. Metabolic Profiles of 5F-MDMB-PICA in Human Urine, Serum, and Hair Samples Using LC-Q Exactive HF MS. Journal of analytical toxicology. 2021-04-16. PMID:33860792. |
in 2020, 5f-mdmb-pica (5f-mdmb-2201) was one of the most common synthetic cannabinoids (scs) identified in drugs seized by the beijing drug control agency and it was categorized as schedule ii by the united nations office on drugs and crime (unodc) in march 2020. |
2021-04-16 |
2023-08-13 |
human |
| Nunzia La Maida, Manuela Pellegrini, Esther Papaseit, Clara Pérez-Mañá, Lourdes Poyatos, Mireia Ventura, Liliana Galindo, Francesco Paolo Busardò, Simona Pichini, Magí Farré, Emilia Marche. Determination of the Synthetic Cannabinoids JWH-122, JWH-210, UR-144 in Oral Fluid of Consumers by GC-MS and Quantification of Parent Compounds and Metabolites by UHPLC-MS/MS. International journal of molecular sciences. vol 21. issue 24. 2021-03-04. PMID:33321929. |
the consumption of synthetic cannabinoids (scs) has significantly increased in the last decade and the analysis of scs and their metabolites in human specimens is gaining interest in clinical and forensic toxicology. |
2021-03-04 |
2023-08-13 |
human |
| Kenneth B Walsh, Haley K Anderse. Molecular Pharmacology of Synthetic Cannabinoids: Delineating CB1 Receptor-Mediated Cell Signaling. International journal of molecular sciences. vol 21. issue 17. 2021-02-22. PMID:32854313. |
synthetic cannabinoids (scs) are a class of new psychoactive substances (npss) that exhibit high affinity binding to the cannabinoid cb1 and cb2 receptors and display a pharmacological profile similar to the phytocannabinoid (-)- |
2021-02-22 |
2023-08-13 |
Not clear |
| João Alexandre, Rui Malheiro, Diana Dias da Silva, Helena Carmo, Félix Carvalho, João Pedro Silv. The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CB International journal of molecular sciences. vol 21. issue 17. 2021-02-17. PMID:32872617. |
the synthetic cannabinoids thj-2201 and 5f-pb22 enhance in vitro cb recreational use of synthetic cannabinoids (scs) before and during pregnancy poses a major public health risk, due to the potential onset of neurodevelopmental disorders in the offspring. |
2021-02-17 |
2023-08-13 |
Not clear |
| Anna Pinson, Azure L Yarbrough, John M Bush, Christian V Cabanlong, Amal Shoeib, Bailey K Jackson, Saki Fukuda, Jyoti Gogoi, William E Fantegrossi, Keith McCain, Paul L Prather, Ryoichi Fujiwara, Anna Radominska-Pandy. Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity. Pharmacology, biochemistry, and behavior. vol 195. 2021-02-08. PMID:32413436. |
akb48 and its fluorinated derivative 5f-akb48 are synthetic cannabinoids (scs) which have caused hospitalizations and deaths in human users. |
2021-02-08 |
2023-08-13 |
mouse |
| Orapan Apirakkan, Simon Hudson, Lewis Couchman, David Cowan, Stephen Morley, Vincenzo Abbat. The First Reported Case of a Synthetic Cannabinoid Ethyl Ester Detected in a Postmortem Blood Toxicological Analysis. Journal of analytical toxicology. vol 44. issue 9. 2021-02-04. PMID:32369163. |
metabolites of synthetic cannabinoids (scs) are widely used as markers for identifying scs' intake. |
2021-02-04 |
2023-08-13 |
Not clear |
| Eef L Theunissen, Johannes T Reckweg, Nadia R P W Hutten, Kim P C Kuypers, Stefan W Toennes, Merja A Neukamm, Sebastian Halter, Johannes G Ramaeker. Psychotomimetic symptoms after a moderate dose of a synthetic cannabinoid (JWH-018): implications for psychosis. Psychopharmacology. 2021-01-27. PMID:33501595. |
synthetic cannabinoids (scs) are the largest class of novel psychoactive substances (nps) and are associated with an increased risk of overdosing and adverse events such as psychosis. |
2021-01-27 |
2023-08-13 |
Not clear |
| Tímea Körmöczi, Éva Sija, László Institóris, Éva M Kereszty, István Ilisz, Róbert Berkec. Analytical Methodologies for the Characterization and Analysis of the Parent Compound and Phase I Metabolites of 4F-MDMB-BICA in Human Microsome, Urine, and Blood Samples. Journal of analytical toxicology. 2021-01-06. PMID:33404059. |
4f-mdmb-bica is one of the most dangerous new illicit synthetic cannabinoids (scs) in 2020. |
2021-01-06 |
2023-08-13 |
human |
| Aurora Musa, Nicola Simola, Gessica Piras, Francesca Caria, Emmanuel Shan Onaivi, Maria Antonietta De Luc. Neurochemical and Behavioral Characterization after Acute and Repeated Exposure to Novel Synthetic Cannabinoid Agonist 5-MDMB-PICA. Brain sciences. vol 10. issue 12. 2020-12-31. PMID:33353194. |
since the early 2000s, herbal mixtures containing synthetic cannabinoids (scs), broadly known as spice/k2, have been marketed as a legal marijuana surrogate and have become very popular among adolescents. |
2020-12-31 |
2023-08-13 |
mouse |
| Ismini Kourouni, Bashar Mourad, Hassan Khouli, Janet M Shapiro, Joseph P Mathe. Critical Illness Secondary to Synthetic Cannabinoid Ingestion. JAMA network open. vol 3. issue 7. 2020-12-25. PMID:32687586. |
synthetic cannabinoids (scs), commonly known as k2, spice, or fake weed, are cheap, artificially manufactured recreational drugs that have emerged as a major public health threat in various regions of the us. |
2020-12-25 |
2023-08-13 |
Not clear |
| Douglas R Roehler, Brooke E Hoots, Alana M Vivolo-Kanto. Regional trends in suspected synthetic cannabinoid exposure from January 2016 to September 2019 in the United States. Drug and alcohol dependence. vol 207. 2020-11-19. PMID:31862557. |
the unpredictable physiologic and pharmacologic effects of synthetic cannabinoids (scs) are continuously changing as the chemical structure of scs evolve to avoid classification as a schedule i drug under the controlled substances act in the u.s. |
2020-11-19 |
2023-08-13 |
Not clear |
| Florian Franz, Belal Haschimi, Leslie A King, Volker Auwärte. Extraordinary long detection window of a synthetic cannabinoid metabolite in human urine - Potential impact on therapeutic decisions. Drug testing and analysis. vol 12. issue 3. 2020-11-13. PMID:31944614. |
synthetic cannabinoids (scs) have become established drugs of abuse. |
2020-11-13 |
2023-08-13 |
human |
| Xingxing Diao, Karl B Scheidweiler, Ariane Wohlfarth, Mingshe Zhu, Shaokun Pang, Marilyn A Huesti. Strategies to distinguish new synthetic cannabinoid FUBIMINA (BIM-2201) intake from its isomer THJ-2201: metabolism of FUBIMINA in human hepatocytes. Forensic toxicology. vol 34. 2020-10-01. PMID:27547265. |
since 2013, a new drugs-of-abuse trend attempts to bypass drug legislation by marketing isomers of scheduled synthetic cannabinoids (scs), e.g., fubimina (bim-2201) and thj-2201. |
2020-10-01 |
2023-08-13 |
human |
| Ahmet Bulent Yazici, Esra Yazici, Atila Ero. Delirium and High Creatine Kinase and Myoglobin Levels Related to Synthetic Cannabinoid Withdrawal. Case reports in medicine. vol 2017. 2020-10-01. PMID:28487743. |
synthetic cannabinoids (scs) are included in a group of drugs called new psychoactive substances. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ahmet Bulent Yazici, Esra Yazici, Atila Ero. Delirium and High Creatine Kinase and Myoglobin Levels Related to Synthetic Cannabinoid Withdrawal. Case reports in medicine. vol 2017. 2020-10-01. PMID:28487743. |
effects of scs on the central nervous system are similar to other cannabinoids, but 2-100 times more potent than marijuana. |
2020-10-01 |
2023-08-13 |
Not clear |
| Shuji Kanek. Motor vehicle collisions caused by the 'super-strength' synthetic cannabinoids, MAM-2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014. Forensic toxicology. vol 35. issue 2. 2020-10-01. PMID:28706566. |
in 93 out of 96 investigated cases, the causative agents were a variety of synthetic cannabinoids (scs). |
2020-10-01 |
2023-08-13 |
Not clear |