| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T W Grim, A J Morales, B F Thomas, J L Wiley, G W Endres, S S Negus, A H Lichtma. Apparent CB The Journal of pharmacology and experimental therapeutics. vol 362. issue 1. 2017-08-01. PMID:28442584. |
apparent cb synthetic cannabinoids (scs) represent an emerging class of abused drugs associated with psychiatric complications and other substantial health risks. |
2017-08-01 |
2023-08-13 |
human |
| R Solimini, F P Busardò, M C Rotolo, S Ricci, L Mastrobattista, C Mortali, S Graziano, M Pellegrini, N M di Luca, I Palm. Hepatotoxicity associated to synthetic cannabinoids use. European review for medical and pharmacological sciences. vol 21. issue 1 Suppl. 2017-07-26. PMID:28379600. |
synthetic cannabinoids (scs) are psychotropic compounds, chemically created in laboratory to mimic cannabinergic brain activity of delta-9 tetrahydrocannabinol. |
2017-07-26 |
2023-08-13 |
Not clear |
| R Solimini, F P Busardò, M C Rotolo, S Ricci, L Mastrobattista, C Mortali, S Graziano, M Pellegrini, N M di Luca, I Palm. Hepatotoxicity associated to synthetic cannabinoids use. European review for medical and pharmacological sciences. vol 21. issue 1 Suppl. 2017-07-26. PMID:28379600. |
increasingly popular as substances of abuse since the 2000s, scs were produced initially to bind and study cannabinoid receptors (they also can be called synthetic cannabimimetics) failing in eliminating the psychoactive effects. |
2017-07-26 |
2023-08-13 |
Not clear |
| Nadine Schaefer, Andreas G Helfer, Mattias Kettner, Matthias W Laschke, Julia Schlote, Andreas H Ewald, Markus R Meyer, Michael D Menger, Hans H Maurer, Peter H Schmid. Metabolic patterns of JWH-210, RCS-4, and THC in pig urine elucidated using LC-HR-MS/MS: Do they reflect patterns in humans? Drug testing and analysis. vol 9. issue 4. 2017-07-18. PMID:27328899. |
the knowledge of pharmacokinetic (pk) properties of synthetic cannabinoids (scs) is important for interpretation of analytical results found for example in intoxicated individuals. |
2017-07-18 |
2023-08-13 |
human |
| Rahime Inci, Kiymet Handan Kelekci, Nihan Oguz, Semsettin Karaca, Baris Karadas, Adem Bayrakc. Dermatological aspects of synthetic cannabinoid addiction. Cutaneous and ocular toxicology. vol 36. issue 2. 2017-07-11. PMID:27028361. |
synthetic cannabinoids (scs) have recently become one of the most abused substances among young population and have caused severe health consequences in our country and worldwide. |
2017-07-11 |
2023-08-13 |
Not clear |
| L Sun, L Tai, Q Qiu, R Mitchell, S Fleetwood-Walker, E A Joosten, C W Cheun. Endocannabinoid activation of CB European journal of pain (London, England). vol 21. issue 5. 2017-05-30. PMID:28107590. |
endocannabinoid activation of cb spinal cord stimulation (scs) has been shown to be effective in the management of certain neuropathic pain conditions, however, the underlying mechanisms are incompletely understood. |
2017-05-30 |
2023-08-13 |
Not clear |
| X Diao, M A Huesti. Approaches, Challenges, and Advances in Metabolism of New Synthetic Cannabinoids and Identification of Optimal Urinary Marker Metabolites. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27727455. |
we review approaches for determining metabolism of new synthetic cannabinoids (scs), and challenges and advances in identifying optimal urinary marker metabolites of sc intake. |
2017-05-29 |
2023-08-13 |
human |
| R Le Boisselier, J Alexandre, V Lelong-Boulouard, D Debruyn. Focus on cannabinoids and synthetic cannabinoids. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27861784. |
the recent emergence of a multitude of synthetic cannabinoids (scs) has generated a wealth of new information, suggesting the usefulness of state-of-the-art on lato sensu cannabinoids. |
2017-05-29 |
2023-08-13 |
Not clear |
| R Le Boisselier, J Alexandre, V Lelong-Boulouard, D Debruyn. Focus on cannabinoids and synthetic cannabinoids. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27861784. |
scs desired and adverse effects are considered to be more intense than those observed with cannabis smoking, which is partly explained by the full agonist activity and higher affinity for cannabinoid receptors. |
2017-05-29 |
2023-08-13 |
Not clear |
| R Le Boisselier, J Alexandre, V Lelong-Boulouard, D Debruyn. Focus on cannabinoids and synthetic cannabinoids. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27861784. |
neurological and cardiovascular side effects observed after cannabinoid poisoning generally respond to conventional supportive care, but severe outcomes may occur in a minority of cases, mainly observed with scs. |
2017-05-29 |
2023-08-13 |
Not clear |
| R Le Boisselier, J Alexandre, V Lelong-Boulouard, D Debruyn. Focus on cannabinoids and synthetic cannabinoids. Clinical pharmacology and therapeutics. vol 101. issue 2. 2017-05-29. PMID:27861784. |
the likelihood of severe abuse and addiction produced by scs are of concern for the scientific community also interested in the potential therapeutic value of cannabinoids. |
2017-05-29 |
2023-08-13 |
Not clear |
| T W Grim, A J Morales, M M Gonek, J L Wiley, B F Thomas, G W Endres, L J Sim-Selley, D E Selley, S S Negus, A H Lichtma. Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays. The Journal of pharmacology and experimental therapeutics. vol 359. issue 2. 2017-05-26. PMID:27535976. |
synthetic cannabinoids (scs) are an emerging class of abused drugs that differ from each other and the phytocannabinoid ∆ |
2017-05-26 |
2023-08-13 |
mouse |
| Paul Glue, Julie Courts, Andrew Gray, Tess Patterso. Influence of law changes affecting synthetic cannabinoid availability and frequency of hospital presentations: 4-year national survey. The New Zealand medical journal. vol 129. issue 1433. 2017-04-21. PMID:27349159. |
we previously reported that passage of the 2013 psychoactive substances act (psa), which limited retail availability of synthetic cannabinoids (scs), was followed by reduced numbers of presentations to one psychiatric emergency service. |
2017-04-21 |
2023-08-13 |
Not clear |
| Andrea Bileck, Franziska Ferk, Halh Al-Serori, Verena J Koller, Besnik Muqaku, Alexander Haslberger, Volker Auwärter, Christopher Gerner, Siegfried Knasmülle. Impact of a synthetic cannabinoid (CP-47,497-C8) on protein expression in human cells: evidence for induction of inflammation and DNA damage. Archives of toxicology. vol 90. issue 6. 2017-02-20. PMID:26194647. |
synthetic cannabinoids (scs) are marketed worldwide as legal surrogates for marihuana. |
2017-02-20 |
2023-08-13 |
human |
| David Mathai, Mollie Gordon, Peter Muchmore, Anu Matorin, Asim Shah, Nidal Moukadda. Paradoxical increase in synthetic cannabinoid emergency-related presentations after a citywide ban: Lessons from Houston, Texas. Bulletin of the Menninger Clinic. vol 80. issue 4. 2017-02-13. PMID:27936903. |
synthetic cannabinoids (scs) have become a major drug of abuse associated with severe hospital presentations. |
2017-02-13 |
2023-08-13 |
Not clear |
| Nadine Schaefer, Jan-Georg Wojtyniak, Mattias Kettner, Julia Schlote, Matthias W Laschke, Andreas H Ewald, Thorsten Lehr, Michael D Menger, Hans H Maurer, Peter H Schmid. Pharmacokinetics of (synthetic) cannabinoids in pigs and their relevance for clinical and forensic toxicology. Toxicology letters. vol 253. 2017-02-03. PMID:27113702. |
synthetic cannabinoids (scs) are gaining increasing importance in clinical and forensic toxicology. |
2017-02-03 |
2023-08-13 |
human |
| Yuri P Springer, Roy Gerona, Erich Scheunemann, Sarah L Shafer, Thomas Lin, Samuel D Banister, Michael P Cooper, Louisa J Castrodale, Michael Levy, Jay C Butler, Joseph B McLaughli. Increase in Adverse Reactions Associated with Use of Synthetic Cannabinoids - Anchorage, Alaska, 2015-2016. MMWR. Morbidity and mortality weekly report. vol 65. issue 40. 2017-01-11. PMID:27736839. |
in july 2015, personnel in the alaska division of public health's section of epidemiology became aware of an increase in the number of patients being treated in anchorage hospital emergency departments for adverse reactions associated with use of synthetic cannabinoids (scs). |
2017-01-11 |
2023-08-13 |
Not clear |
| Yuri P Springer, Roy Gerona, Erich Scheunemann, Sarah L Shafer, Thomas Lin, Samuel D Banister, Michael P Cooper, Louisa J Castrodale, Michael Levy, Jay C Butler, Joseph B McLaughli. Increase in Adverse Reactions Associated with Use of Synthetic Cannabinoids - Anchorage, Alaska, 2015-2016. MMWR. Morbidity and mortality weekly report. vol 65. issue 40. 2017-01-11. PMID:27736839. |
scs are a chemically diverse class of designer drugs that bind to the same cannabinoid receptors as tetrahydrocannabinol, the main psychoactive component of cannabis. |
2017-01-11 |
2023-08-13 |
Not clear |
| Marina Dronova, Evgeny Smolianitski, Ovadia Le. Electrooxidation of New Synthetic Cannabinoids: Voltammetric Determination of Drugs in Seized Street Samples and Artificial Saliva. Analytical chemistry. vol 88. issue 8. 2016-12-13. PMID:26905258. |
the electrochemical sensing of new psychoactive substances, synthetic cannabinoids (scs), commonly marketed under the trade name "spice" is explored for the first time. |
2016-12-13 |
2023-08-13 |
Not clear |
| Ziva D Coope. Adverse Effects of Synthetic Cannabinoids: Management of Acute Toxicity and Withdrawal. Current psychiatry reports. vol 18. issue 5. 2016-12-13. PMID:27074934. |
although several chemical structural classes of synthetic cannabinoids (scs) were recently classified as schedule i substances, rates of use and cases of serious toxic effects remain high. |
2016-12-13 |
2023-08-13 |
Not clear |