| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Onodera, L Tuomisto, U Tacke, M Airaksine. Strain differences in regional brain histamine levels between genetically epilepsy-prone and resistant rats. Methods and findings in experimental and clinical pharmacology. vol 14. issue 1. 1992-08-06. PMID:1619966. |
histamine levels in the striatum, hippocampus, amygdala, midbrain, thalamus and hypothalamus of km rats were significantly lower than in the epilepsy-resistant wistar rats. |
1992-08-06 |
2023-08-11 |
rat |
| K Onodera, A Yamatodani, T Watanab. Effects of alpha-fluoromethylhistidine on locomotor activity, brain histamine and catecholamine contents in rats. Methods and findings in experimental and clinical pharmacology. vol 14. issue 2. 1992-07-08. PMID:1598029. |
one and 3 hours after fmh injection, the histamine levels significantly decreased in the hypothalamus, cortex and thalamus, slightly in the olfactory bulb, amygdala, pons-medulla oblongata and midbrain, but very little in the striatum, hippocampus, cerebellum and pituitary. |
1992-07-08 |
2023-08-11 |
rat |
| M Daoust, E Legrand, M Gewiss, C Heidbreder, P DeWitte, G Tran, P Durbi. Acamprosate modulates synaptosomal GABA transmission in chronically alcoholised rats. Pharmacology, biochemistry, and behavior. vol 41. issue 4. 1992-06-30. PMID:1594633. |
at the end of the experiment, brains areas (cortex, hippocampus, thalamus, striatum, and olfactory bulbs) were dissected for the study of synaptosomal 3h-gaba uptake. |
1992-06-30 |
2023-08-11 |
rat |
| R Widmann, C Weber, P Bonnekoh, M Schlenker, K A Hossman. Neuronal damage after repeated 5 minutes of ischemia in the gerbil is preceded by prolonged impairment of protein metabolism. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 12. issue 3. 1992-05-27. PMID:1569137. |
control values of protein synthesis were 14.6 +/- 2.2, 5.8 +/- 2.3, 14.2 +/- 3.1, and 10.0 +/- 3.8 nmol g-1 min-1 (means +/- sd) in the frontal cortex, striatum, ca1 sector, and thalamus, respectively. |
1992-05-27 |
2023-08-11 |
Not clear |
| T C Howerton, M R Murphy, S A Miller, S L Hartgrave. Differential sensitivity of CNS regions to acetylcholinesterase inhibition following chronic low-dose soman treatment in the rat. Psychopharmacology. vol 105. issue 3. 1992-04-13. PMID:1798835. |
the observed regional brain sensitivity to ache inhibition can be described in the following order: frontal cortex = piriform cortex greater than hippocampus = cerebellum = thalamus greater than striatum = hypothalamus. |
1992-04-13 |
2023-08-11 |
rat |
| R P Verte. A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat. The Journal of comparative neurology. vol 313. issue 4. 1992-03-19. PMID:1783685. |
the following subcortical nuclei receive dense projections from the dr: ventral regions of the midbrain central gray including the 'supraoculomotor central gray' region, the ventral tegmental area, the substantia nigra-pars compacta, midline and intralaminar nuclei of the thalamus including the posterior paraventricular, the parafascicular, reuniens, rhomboid, intermediodorsal/mediodorsal, and central medial thalamic nuclei, the central, lateral and basolateral nuclei of the amygdala, posteromedial regions of the striatum, the bed nucleus of the stria terminalis, the lateral septal nucleus, the lateral preoptic area, the substantia innominata, the magnocellular preoptic nucleus, the endopiriform nucleus, and the ventral pallidum. |
1992-03-19 |
2023-08-11 |
rat |
| H A Baldwin, R J De Souza, G S Sarna, T K Murray, A R Green, A J Cros. Measurements of tacrine and monoamines in brain by in vivo microdialysis argue against release of monoamines by tacrine at therapeutic doses. British journal of pharmacology. vol 103. issue 4. 1991-10-31. PMID:1912982. |
no evidence was obtained by in vivo dialysis for tha inducing dopamine release from striatum or 5-hydroxytryptamine (5-ht) release from the frontal cortex. |
1991-10-31 |
2023-08-11 |
rat |
| Y Yasui, C B Saper, D F Cechett. Calcitonin gene-related peptide (CGRP) immunoreactive projections from the thalamus to the striatum and amygdala in the rat. The Journal of comparative neurology. vol 308. issue 2. 1991-10-15. PMID:1890240. |
calcitonin gene-related peptide (cgrp) immunoreactive projections from the thalamus to the striatum and amygdala in the rat. |
1991-10-15 |
2023-08-11 |
rat |
| M Y Globus, M D Ginsberg, R Bust. Excitotoxic index--a biochemical marker of selective vulnerability. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1679223. |
similar ischemia-induced increases in glutamate, gaba, and glycine were observed in both striatum and thalamus (19-25 fold, 43-52 fold, and 3-4 fold, respectively). |
1991-09-30 |
2023-08-11 |
rat |
| M Y Globus, M D Ginsberg, R Bust. Excitotoxic index--a biochemical marker of selective vulnerability. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1679223. |
glycine levels remained two-fold higher than baseline in the striatum but fell to baseline in the thalamus. |
1991-09-30 |
2023-08-11 |
rat |
| K Gulya, K A Grant, P Valverius, P L Hoffman, B Tabakof. Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal. Brain research. vol 547. issue 1. 1991-09-05. PMID:1830510. |
the current studies, using quantitative autoradiography, demonstrate that chronic ethanol ingestion also produces increases in mk-801 binding in cerebral cortex, striatum and thalamus, as well as in hippocampus. |
1991-09-05 |
2023-08-11 |
mouse |
| L C Mahan, L D McVittie, E M Smyk-Randall, H Nakata, F J Monsma, C R Gerfen, D R Sible. Cloning and expression of an A1 adenosine receptor from rat brain. Molecular pharmacology. vol 40. issue 1. 1991-08-29. PMID:1857334. |
northern blot and in situ hybridization analyses of receptor mrna in brain tissues revealed two transcripts of 5.6 and 3.1 kilobases, both of which were abundant in cortex, cerebellum, hippocampus, and thalamus, with lower levels in olfactory bulb, striatum, mesencephalon, and retina. |
1991-08-29 |
2023-08-11 |
mouse |
| N Ogawa, K Mizukawa, K Haba, M Asanuma, A Mor. Chronic bifemelane hydrochloride administration enhances muscarinic cholinergic receptor binding in the senescent rat brain. Journal of medicine. vol 22. issue 1. 1991-08-20. PMID:2072048. |
in senescent rats, the binding ability of muscarinic cholinergic receptors (mcr) was markedly decreased in the cerebral cortex, hippocampus, thalamus, and the striatum compared with young adult rats. |
1991-08-20 |
2023-08-11 |
rat |
| S Y Sakurai, J H Cha, J B Penney, A B Youn. Regional distribution and properties of [3H]MK-801 binding sites determined by quantitative autoradiography in rat brain. Neuroscience. vol 40. issue 2. 1991-06-12. PMID:2027471. |
[3h]mk-801 binding was heterogeneously distributed throughout the brain with the following order of binding densities: hippocampal formation greater than cortical areas greater than striatum greater than thalamus. |
1991-06-12 |
2023-08-11 |
rat |
| S Simler, L Ciesielski, S Gobaille, P Mande. Alterations in synaptosomal neurotransmitter amino acids in "petit-mal" rats at a daytime and a nighttime. Neurochemical research. vol 15. issue 11. 1991-05-30. PMID:1982457. |
the synaptosomal fractions of 6 brain areas-olfactory tubercles (ot), frontal cortex (fc), striatum (sr), amygdala (a), thalamus (th), hypothalamus (hy) - have been analyzed for their neurotransmitter amino acids (aa) content in wistar rats exhibiting "petit-mal" epilepsy (pm-e) and in controls (c). |
1991-05-30 |
2023-08-11 |
rat |
| K J Reinikainen, H Soininen, P J Riekkine. Neurotransmitter changes in Alzheimer's disease: implications to diagnostics and therapy. Journal of neuroscience research. vol 27. issue 4. 1991-04-26. PMID:1981917. |
serotonin (5ht) concentrations were reduced (by 21-37%) in hippocampal cortex, hippocampus and striatum; and 5ht metabolite levels were lowered (by 39-54%) in three cortical areas, thalamus and putamen in ad patients. |
1991-04-26 |
2023-08-11 |
cat |
| M S Benedetti, P Dostert, D Barone, C Efthymiopoulos, G Peretti, R Roncucc. In vivo interaction of cabergoline with rat brain dopamine receptors labelled with [3H]N-n-propylnorapomorphine. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:1981553. |
these effects were observed in all areas of the rat brain studied (striatum, olfactory tubercles, adeno- and neurohypophysis, thalamus and hypothalamus). |
1991-04-15 |
2023-08-11 |
rat |
| R Cortés, S Ceccatelli, M Schalling, T Hökfel. Differential effects of intracerebroventricular colchicine administration on the expression of mRNAs for neuropeptides and neurotransmitter enzymes, with special emphasis on galanin: an in situ hybridization study. Synapse (New York, N.Y.). vol 6. issue 4. 1991-03-25. PMID:1705058. |
in addition, after colchicine treatment, gal mrna appears to be induced in the ipsilateral hemisphere in regions such as the cortex, hippocampus, striatum, lateral septum, and some nuclei of the thalamus as well as within white matter, where it cannot be detected in control animals. |
1991-03-25 |
2023-08-11 |
Not clear |
| S L Dewey, J D Brodie, J S Fowler, R R MacGregor, D J Schlyer, P T King, D L Alexoff, N D Volkow, C Y Shiue, A P Wol. Positron emission tomography (PET) studies of dopaminergic/cholinergic interactions in the baboon brain. Synapse (New York, N.Y.). vol 6. issue 4. 1991-03-25. PMID:1981112. |
pretreatment with unlabelled nmsp, a potent dopaminergic antagonist, reduced the incorporation of [n-11c-methyl]benztropine in all brain regions, with the greatest effect being in the corpus striatum greater than cortex greater than thalamus greater than cerebellum, but did not alter the rate of metabolism of the labelled benztropine in the plasma. |
1991-03-25 |
2023-08-11 |
Not clear |
| S Subramaniam, P McGonigl. Quantitative autoradiographic characterization of the binding of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine ([3H]MK-801) in rat brain: regional effects of polyamines. The Journal of pharmacology and experimental therapeutics. vol 256. issue 2. 1991-03-21. PMID:1671602. |
the polyamine agonists spermine and spermidine enhanced [3h]mk-801 binding in all regions studied, with increases ranging from 18% in the thalamus to 106% in the ventromedial striatum. |
1991-03-21 |
2023-08-11 |
rat |