| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Volker A Coenen, Thomas E Schlaepfer, Bastian E A Sajonz, Peter C Reinacher, Máté D Döbrössy, Marco Reiser. "The Heart Asks Pleasure First"-Conceptualizing Psychiatric Diseases as Brain sciences. vol 12. issue 4. 2022-04-21. PMID:35447971. |
"the heart asks pleasure first"-conceptualizing psychiatric diseases as more than a decade ago, deep brain stimulation (dbs) of the superolateral medial forebrain bundle (slmfb), as part of the greater mfb system, had been proposed as a putative yet experimental treatment strategy for therapy refractory depression (trd) and later for obsessive-compulsive disorders (ocd). |
2022-04-21 |
2023-08-13 |
Not clear |
| Vasilios Pallikaras, Peter Shizga. The Convergence Model of Brain Reward Circuitry: Implications for Relief of Treatment-Resistant Depression by Deep-Brain Stimulation of the Medial Forebrain Bundle. Frontiers in behavioral neuroscience. vol 16. 2022-04-18. PMID:35431828. |
the convergence model of brain reward circuitry: implications for relief of treatment-resistant depression by deep-brain stimulation of the medial forebrain bundle. |
2022-04-18 |
2023-08-13 |
rat |
| Vasilios Pallikaras, Peter Shizga. The Convergence Model of Brain Reward Circuitry: Implications for Relief of Treatment-Resistant Depression by Deep-Brain Stimulation of the Medial Forebrain Bundle. Frontiers in behavioral neuroscience. vol 16. 2022-04-18. PMID:35431828. |
deep-brain stimulation of the medial forebrain bundle (mfb) can provide effective, enduring relief of treatment-resistant depression. |
2022-04-18 |
2023-08-13 |
rat |
| Hiroshi Kunugi, Maria Tikhonov. Recent advances in understanding depressive disorder: Possible relevance to brain stimulation therapies. Progress in brain research. vol 270. issue 1. 2022-04-09. PMID:35396024. |
robust evidence on the decreased homovanillic acid in the cerebrospinal fluid (csf) of patients with mdd supports a rationale for therapeutic stimulation of the medial forebrain bundle activating the dopamine reward system. |
2022-04-09 |
2023-08-13 |
Not clear |
| Dora M Meyer, Susanne Spanier, Hannah M Kilian, Marco Reisert, Horst Urbach, Bastian Ea Sajonz, Peter C Reinacher, Claus Normann, Katharina Domschke, Volker A Coenen, Thomas E Schlaepfe. Efficacy of superolateral medial forebrain bundle deep brain stimulation in obsessive-compulsive disorder. Brain stimulation. 2022-03-29. PMID:35346894. |
efficacy of superolateral medial forebrain bundle deep brain stimulation in obsessive-compulsive disorder. |
2022-03-29 |
2023-08-13 |
Not clear |
| Albert J Fenoy, Paul E Schulz, Marsal Sanches, Sudhakar Selvaraj, Christina L Burrows, Bashar Asir, Christopher R Conner, Joao Quevedo, Jair C Soare. Deep brain stimulation of the "medial forebrain bundle": sustained efficacy of antidepressant effect over years. Molecular psychiatry. 2022-03-15. PMID:35288633. |
deep brain stimulation (dbs) to the superolateral branch of the medial forebrain bundle (mfb) has emerged as a quite efficacious therapy for treatment resistant depression (trd), leading to rapid antidepressant effects. |
2022-03-15 |
2023-08-13 |
Not clear |
| Tobias Bracht, Nicolas Mertse, Sebastian Walther, Karin Lüdi, Sigrid Breit, Andrea Federspiel, Roland Wiest, Niklaus Denie. Link between structural connectivity of the medial forebrain bundle, functional connectivity of the ventral tegmental area, and anhedonia in unipolar depression. NeuroImage. Clinical. vol 34. 2022-02-13. PMID:35152053. |
link between structural connectivity of the medial forebrain bundle, functional connectivity of the ventral tegmental area, and anhedonia in unipolar depression. |
2022-02-13 |
2023-08-13 |
human |
| Yixin Tong, Lisa Pfeiffer, Tsvetan Serchov, Volker A Coenen, Máté D Döbröss. Optogenetic stimulation of ventral tegmental area dopaminergic neurons in a female rodent model of depression: The effect of different stimulation patterns. Journal of neuroscience research. 2022-01-28. PMID:35088434. |
recent clinical trials indicate that deep brain stimulation of the superolateral medial forebrain bundle (mfb) can have rapid and long-term antidepressant effects in patients with treatment-resistant depression. |
2022-01-28 |
2023-08-13 |
rat |
| Yusuke Shibata, Airi Yoshimoto, Kotaro Yamashiro, Yuji Ikegaya, Nobuyoshi Matsumot. Delayed reinforcement hinders subsequent extinction. Biochemical and biophysical research communications. vol 591. 2022-01-07. PMID:34995981. |
to address this question, we performed electrical stimulation of the rat medial forebrain bundle (mfb), a part of the brain reward system, and an operant task in which the mfb was electrically stimulated 0.1 s (immediate condition) or 1 s (delayed condition) after the rat's nose was poked. |
2022-01-07 |
2023-08-13 |
rat |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Yoonbae Oh, Hojin Shi. Cocaine increases stimulation-evoked serotonin efflux in the nucleus accumbens. Journal of neurophysiology. 2022-01-05. PMID:34986049. |
stimulation was applied to the medial forebrain bundle using 60 hz, 2 ms, 0.2 ma, 2 s biphasic pulses before and after cocaine (2 mg/kg i.v.) |
2022-01-05 |
2023-08-13 |
rat |
| Rayanne Poletti Guimarães, Danilo Leandro Ribeiro, Keila Bariotto Dos Santos, Lívea Dornela Godoy, Mirella Rosine Corrêa, Fernando Eduardo Padovan-Net. The 6-hydroxydopamine Rat Model of Parkinson's Disease. Journal of visualized experiments : JoVE. issue 176. 2021-11-15. PMID:34779439. |
the infusion of the neurotoxin, 6-hydroxydopamine (6-ohda), into a medial forebrain bundle (mfb) of rats reproduces the severe destruction of dopaminergic neurons and simulates pd symptoms. |
2021-11-15 |
2023-08-13 |
human |
| Ingrid Morales, Ricardo Puertas-Avendaño, Alberto Sanchez, Adrian Perez-Barreto, Clara Rodriguez-Sabate, Manuel Rodrigue. Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson's disease: removing axonal debris. Translational neurodegeneration. vol 10. issue 1. 2021-11-06. PMID:34727977. |
neuroinflammation accelerates the cell degeneration and may be critical for the transition between the slow physiological and the rapid pathological degeneration of da cells, particularly when it activates microglial cells of the medial forebrain bundle near dopaminergic axons. |
2021-11-06 |
2023-08-13 |
Not clear |
| Graziella R Molska, Lyvia Izaura G Paula-Freire, Marna E Sakalem, Daniele O Köhn, Giuseppina Negri, Elisaldo A Carlini, Fúlvio R Mende. Green coffee extract attenuates Parkinson's-related behaviors in animal models. Anais da Academia Brasileira de Ciencias. vol 93. issue suppl 4. 2021-11-05. PMID:34730624. |
the effects of the oral treatment with green (non-roasted) coffee extracts (ce, 100 or 400 mg/kg) and caffeine (31.2 mg/kg) were evaluated on catalepsy induced by haloperidol in mice, and unilateral 6-ohda lesion of medial forebrain bundle (mfb) or striatum in rats. |
2021-11-05 |
2023-08-13 |
mouse |
| Ann-Kristin Riedesel, Simeon O A Helgers, Arif Abdulbaki, Gökce Hatipoglu Majernik, Mesbah Alam, Joachim K Krauss, Kerstin Schwab. Severity assessment of complex and repeated intracranial surgery in rats. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. 2021-11-03. PMID:34731861. |
in the parkinson's model, sprague dawley (sd) rats received unilateral injection of 6-ohda (n=11) or vehicle (n=7) into the medial forebrain bundle as first operation. |
2021-11-03 |
2023-08-13 |
rat |
| Luca Pagliaroli, Abel Fothi, Ester Nespoli, Istvan Liko, Borbala Veto, Piroska Devay, Flora Szeri, Bastian Hengerer, Csaba Barta, Tamas Arany. Riluzole Administration to Rats with Levodopa-Induced Dyskinesia Leads to Loss of DNA Methylation in Neuronal Genes. Cells. vol 10. issue 6. 2021-11-01. PMID:34207710. |
the rat model of levodopa-induced dyskinesia is a unilateral lesion with 6-hydroxydopamine in the medial forebrain bundle, followed by the repeated administration of levodopa. |
2021-11-01 |
2023-08-13 |
rat |
| Michael B Prit. Thalamic reticular nucleus in Alligator mississippiensis: Soma and dendritic morphology. The Journal of comparative neurology. vol 529. issue 17. 2021-10-29. PMID:34031891. |
in alligator, the four trn divisions are the dorsal peduncular nucleus, the perireticular nucleus, the interstitial nucleus, and the neurons in the medial forebrain bundle associated with the interstitial nucleus. |
2021-10-29 |
2023-08-13 |
Not clear |
| Seungleal Brian Paek, Emily Jane Knight, Su-Youne Chang, J Luis Lujan, Dong Pyo Jang, Kevin E Bennet, Kendall H Le. Dopamine measurement during prolonged deep brain stimulation: a proof-of-principle study of paired pulse voltammetry. Biomedical engineering letters. vol 3. issue 1. 2021-10-21. PMID:24688801. |
here we demonstrate the efficacy of a modified fscv technique, paired pulse voltammetry (ppv), in detecting dopamine (da) release in the caudate nucleus during long-term electrical stimulation of the medial forebrain bundle (mfb) in the rat. |
2021-10-21 |
2023-08-12 |
rat |
| Adam Gordon-Fennell, Garret D Stube. Illuminating subcortical GABAergic and glutamatergic circuits for reward and aversion. Neuropharmacology. vol 198. 2021-10-14. PMID:34375625. |
here, we review the past decade of optogenetic experiments to study the neural circuitry of reinforcement and reward/aversion with a focus on the mesolimbic dopamine system and brain areas along the medial forebrain bundle (mfb). |
2021-10-14 |
2023-08-13 |
Not clear |
| Karīna Narbute, Vladimirs Pilipenko, Jolanta Pupure, Toms Klinovičs, Jānis Auders, Ugnė Jonavičė, Karolina Kriaučiūnaitė, Augustas Pivoriūnas, Vija Kluš. Time-Dependent Memory and Gait Improvement by Intranasally-Administered Extracellular Vesicles in Parkinson's Disease Model Rats. Cellular and molecular neurobiology. vol 41. issue 3. 2021-09-30. PMID:32410106. |
we have recently demonstrated that extracellular vesicles (evs) derived from the human teeth stem cells improve motor symptoms and normalize tyrosine hydroxylase (th) expression in the nigrostriatal structures of parkinson's disease (pd) model rats obtained by 6-hydroxydopamine (6-ohda) unilateral injection into the medial forebrain bundle (mfb). |
2021-09-30 |
2023-08-13 |
human |
| Owen M Peters, Alexandra Weiss, Jake Metterville, Lina Song, Robert Logan, Gaynor A Smith, Michael A Schwarzschild, Christian Mueller, Robert H Brown, Marc Freema. Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease. Neurobiology of disease. vol 155. 2021-09-03. PMID:33892050. |
in sarm1 deficient mice, we observed a significant delay in the degeneration of severed dopaminergic axons distal to a 6-ohda lesion of the medial forebrain bundle (mfb) in the nigrostriatal tract, and an accompanying rescue of morphological, biochemical and behavioural phenotypes. |
2021-09-03 |
2023-08-13 |
mouse |