| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S R Sesack, B S Bunne. Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study. The Journal of pharmacology and experimental therapeutics. vol 248. issue 3. 1989-05-12. PMID:2564893. |
the d2 selective antagonist, sulpiride, specifically attenuated da-induced inhibition of deep layer pfc neurons, without blocking the inhibitory effects of gamma-aminobutyric acid (gaba) or serotonin (5-ht). |
1989-05-12 |
2023-08-11 |
rat |
| A Kalsbeek, J P de Bruin, M A Matthijssen, H B Uyling. Ontogeny of open field activity in rats after neonatal lesioning of the mesocortical dopaminergic projection. Behavioural brain research. vol 32. issue 2. 1989-05-04. PMID:2923656. |
medial vta lesions caused a moderate dopamine depletion in the prefrontal cortex and an almost complete cortical serotonin depletion, and resulted in transient hyperactivity in the open field at postnatal day 25. |
1989-05-04 |
2023-08-11 |
rat |
| A Kalsbeek, J P De Bruin, M G Feenstra, M A Matthijssen, H B Uyling. Neonatal thermal lesions of the mesolimbocortical dopaminergic projection decrease food-hoarding behavior. Brain research. vol 475. issue 1. 1989-02-28. PMID:3214729. |
biochemical analysis demonstrated an approximately 50% depletion of both dopamine and serotonin in the prefrontal cortex of males, whereas noradrenaline levels were unchanged. |
1989-02-28 |
2023-08-11 |
rat |
| K Herrick-Davis, M Titeler, S Leonhardt, R Struble, D Pric. Serotonin 5-HT1D receptors in human prefrontal cortex and caudate: interaction with a GTP binding protein. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:3141589. |
serotonin 5-ht1d receptors in human prefrontal cortex and caudate: interaction with a gtp binding protein. |
1988-12-20 |
2023-08-11 |
human |
| K Herrick-Davis, M Titeler, S Leonhardt, R Struble, D Pric. Serotonin 5-HT1D receptors in human prefrontal cortex and caudate: interaction with a GTP binding protein. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:3141589. |
radioligand binding studies were performed to characterize serotonin 5-ht1d receptors in postmortem human prefrontal cortex and caudate homogenates. |
1988-12-20 |
2023-08-11 |
human |
| K Herrick-Davis, M Titeler, S Leonhardt, R Struble, D Pric. Serotonin 5-HT1D receptors in human prefrontal cortex and caudate: interaction with a GTP binding protein. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:3141589. |
these findings are supportive of the presence of serotonin 5-ht1d receptors in human prefrontal cortex and caudate which appear to be coupled to a gtp binding protein. |
1988-12-20 |
2023-08-11 |
human |
| A J Dunn, N R Hal. Thymic extracts and lymphokine-containing supernatant fluids stimulate the pituitary-adrenal axis, but not cerebral catecholamine or indoleamine metabolism. Brain, behavior, and immunity. vol 1. issue 2. 1988-08-08. PMID:3452441. |
injection of thymosin fraction 5 (tf5) or the supernatant fluid from concanavalin a-stimulated rat spleen cells into mice significantly increased plasma concentrations of corticosterone at 1 or 3 h. however, measurement of the concentrations of the catecholamines, norepinephrine and dopamine, the indoleamine, serotonin, and their major metabolites, in prefrontal cortex, parietal cortex, nucleus accumbens, septum, caudate-putamen, hypothalamus, and brain stem did not indicate any statistically significant changes. |
1988-08-08 |
2023-08-11 |
mouse |
| A J Dun. Changes in plasma and brain tryptophan and brain serotonin and 5-hydroxyindoleacetic acid after footshock stress. Life sciences. vol 42. issue 19. 1988-06-20. PMID:2452945. |
footshock treatment significantly decreased the content of 5-ht in prefrontal cortex and hypothalamus, but not brainstem at 15 min, but the decreases were reversed by 30 min. |
1988-06-20 |
2023-08-11 |
Not clear |
| A J Dun. Changes in plasma and brain tryptophan and brain serotonin and 5-hydroxyindoleacetic acid after footshock stress. Life sciences. vol 42. issue 19. 1988-06-20. PMID:2452945. |
5-hiaa, the major catabolite of 5-ht, increased in prefrontal cortex after 15 min, and in prefrontal cortex and hypothalamus after 30 min footshock. |
1988-06-20 |
2023-08-11 |
Not clear |
| A Cudennec, D Duverger, T Nishikawa, A McRae-Degueurce, E T MacKenzie, B Scatto. Influence of ascending serotonergic pathways on glucose use in the conscious rat brain. I. Effects of electrolytic or neurotoxic lesions of the dorsal and/or median raphé nucleus. Brain research. vol 444. issue 2. 1988-06-02. PMID:3359293. |
the efficacy of both electrolytic and neurotoxic lesions was verified, in each animal, by neurochemical microassay of 5-hydroxytryptamine and its metabolite in samples of striatum, hippocampus and prefrontal cortex. |
1988-06-02 |
2023-08-11 |
rat |
| D J Mokler, K W Stoudt, L C Sherman, R H Rec. The effects of intracranial administration of hallucinogens on operant behavior in the rat. II. 2,5-Dimethoxy-4-methylamphetamine (DOM). Pharmacology, biochemistry, and behavior. vol 28. issue 3. 1988-01-11. PMID:3685066. |
sites were chosen as major areas of the brain 5-hydroxytryptamine (5-ht) system: the dorsal and median raphe nuclei, dorsal hippocampus, lateral habenular nuclei and the prefrontal cortex. |
1988-01-11 |
2023-08-11 |
rat |
| M Boranić, D Pericić, M Poljak-Blazi, V Sverko, T Marott. Suppression of immune response in rats by stress and drugs interfering with metabolism of serotonin. Annals of the New York Academy of Sciences. vol 496. 1987-07-29. PMID:2440371. |
treatment with pcpa also suppressed the pfc response, but this suppression was accompanied by decreased levels of brain serotonin and of 5-hiaa. |
1987-07-29 |
2023-08-11 |
rat |
| E Fride, M Weinstoc. Increased interhemispheric coupling of the dopamine systems induced by prenatal stress. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:2438016. |
dopamine and serotonin turnover rates were measured in the left and right prefrontal cortex, nucleus accumbens and caudate nucleus of adult rats which were stressed prenatally. |
1987-07-16 |
2023-08-11 |
rat |
| K Yamaguchi, T Nabeshima, T Kameyam. Role of dopaminergic and serotonergic neuronal systems in the prefrontal cortex of rats in phencyclidine-induced behaviors. Journal of pharmacobio-dynamics. vol 9. issue 12. 1987-06-01. PMID:3572718. |
pretreatment with p-chlorophenylalanine (300 mg/kg), a serotonin (5-ht) synthesis inhibitor, attenuated head-weaving induced by injection of pcp into the prefrontal cortex. |
1987-06-01 |
2023-08-11 |
rat |
| T Kuroki, T Matsumoto, M Hirano, H Kagoshima, H Yao, H Uchimura, K Nakamura, T Nakahar. Long-lasting effect of systemically administrated caerulein on monoaminergic neuronal pathways in rat brain. Neuropeptides. vol 9. issue 2. 1987-05-27. PMID:2437491. |
significantly elevated 5-hydroxyindoleacetic acid (5hiaa) levels in the prefrontal cortex lateral field, nucleus accumbens, tuberculum olfactorium and striatum after 2 hours, together with a significant increase in striatal serotonin (5ht). |
1987-05-27 |
2023-08-11 |
rat |
| M R Palmer, O Tottmar, R A Deitric. Electrophysiological effects of monoamine-derived aldehydes on single neurons in neocortex and cerebellum in rats. Alcoholism, clinical and experimental research. vol 10. issue 6. 1987-03-18. PMID:2433956. |
serotonin and 5-hydroxy-3-acetaldehyde caused pronounced depression of firing rates both of cerebellar purkinje neurons and neurons in prefrontal cortex. |
1987-03-18 |
2023-08-11 |
rat |
| T Mita, S Hanada, N Nishino, T Kuno, H Nakai, T Yamadori, Y Mizoi, C Tanak. Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics. Biological psychiatry. vol 21. issue 14. 1987-02-13. PMID:2947636. |
serotonin s2 and dopamine d2 receptors in the prefrontal cortex and caudate nucleus of postmortem brains of chronic schizophrenics were studied using 3h-ketanserin and 3h-spiperone, respectively. |
1987-02-13 |
2023-08-11 |
Not clear |
| D J Mokler, K W Stoudt, L C Sherman, R H Rec. The effects of intracranial administration of hallucinogens on operant behavior in the rat. I. Lysergic acid diethylamide. Pharmacology, biochemistry, and behavior. vol 25. issue 4. 1987-01-13. PMID:3538062. |
the sites were chosen as major areas of the brain 5-hydroxytryptamine (5ht) system: the dorsal and median raphe nuclei, dorsal hippocampus, lateral habenular nuclei, and the prefrontal cortex. |
1987-01-13 |
2023-08-11 |
rat |
| O Wolkowitz, M Sutton, M Koulu, R Labarca, L Wilkinson, A Doran, R Hauger, D Pickar, J Crawle. Chronic corticosterone administration in rats: behavioral and biochemical evidence of increased central dopaminergic activity. European journal of pharmacology. vol 122. issue 3. 1986-07-03. PMID:3709658. |
a subgroup of steroid-treated rats which was more behaviorally responsive to corticosterone also showed increased caudate 5-hydroxyindole acetic acid and decreased prefrontal cortex dopamine and serotonin. |
1986-07-03 |
2023-08-11 |
rat |
| A C Andor. Do antipsychotic drugs and serotonin down regulate [3H]-spiroperidol binding sites in human cortex? Life sciences. vol 38. issue 14. 1986-05-19. PMID:2870407. |
therefore antipsychotic compounds and 5-ht appear to down-regulate a subset of antipsychotic binding sites in human prefrontal cortex. |
1986-05-19 |
2023-08-11 |
human |