All Relations between prefrontal cortex and glutamate

Publication Sentence Publish Date Extraction Date Species
Qiu-Yi Dong, Yun-Bin Cao, Hui-Wei Huang, Dan Li, Yanqin Lin, Hua-Jun Che. Metabolic disorder and functional disturbance in the central executive network in minimal hepatic encephalopathy. Cerebral cortex (New York, N.Y. : 1991). vol 34. issue 2. 2024-02-16. PMID:38365269. minimal hepatic encephalopathy patients had decreased myo-inositol / total creatine and choline / total creatine and increased glutamate and glutamine complex / total creatine in right dorsolateral prefrontal cortex (all p ≤ 0.020); decreased static functional connectivity between bilateral dorsolateral prefrontal cortex and between right dorsolateral prefrontal cortex and lateral-inferior temporal cortex (p ≤ 0.001); increased frequency and mean dwell time in state-1 (p ≤ 0.001), which exhibited weakest functional connectivity. 2024-02-16 2024-02-19 Not clear
Christopher J E Denning, Lauren E Madory, Jessica N Herbert, Ryan A Cabrera, Karen K Szumlinsk. Neuropharmacological Evidence Implicating Drug-Induced Glutamate Receptor Dysfunction in Affective and Cognitive Sequelae of Subchronic Methamphetamine Self-Administration in Mice. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339206. relative to naïve controls, ma-experienced mice exhibited several changes in the expression of certain glutamate receptor-related proteins and their downstream effectors within the ventral and dorsal areas of the prefrontal cortex, the hippocampus, and the amygdala, many of which were sex-selective. 2024-02-10 2024-02-12 mouse
Maria Bove, Maria Grazia Morgese, Stefania Dimonte, Vladyslav Sikora, Lisa Pia Agosti, Maria Adelaide Palmieri, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Increased stress vulnerability in the offspring of socially isolated rats: Behavioural, neurochemical and redox dysfunctions. Progress in neuro-psychopharmacology & biological psychiatry. 2024-01-19. PMID:38242425. levels of noradrenaline (na), serotonin (5-ht), 5-hydroxyindoleacetic acid (5-hiaa), glutamate (glu) and gaba were assessed in the prefrontal cortex (pfc). 2024-01-19 2024-01-22 rat
Mahum T Siddiqi, Dhruba Podder, Amanda R Pahng, Alexandria C Athanason, Tali Nadav, Chelsea Cates-Gatto, Max Kreifeldt, Candice Contet, Amanda J Roberts, Scott Edwards, Marisa Roberto, Florence P Varodaya. Prefrontal cortex glutamatergic adaptations in a mouse model of alcohol use disorder. Addiction neuroscience. vol 9. 2023-12-28. PMID:38152067. pfc glutamate neurotransmission is mostly mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type ionotropic receptors (ampars); however preclinical studies have mostly focused on other receptor subtypes. 2023-12-28 2023-12-30 mouse
María Elena Quintanilla, Paola Morales, Daniela Santapau, Alba Ávila, Carolina Ponce, Pablo Berrios-Cárcamo, Belén Olivares, Javiera Gallardo, Marcelo Ezquer, Mario Herrera-Marschitz, Yedy Israel, Fernando Ezque. Chronic Voluntary Morphine Intake Is Associated with Changes in Brain Structures Involved in Drug Dependence in a Rat Model of Polydrug Use. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38069404. we show that wistar-derived outbred uchb rats selected for their high alcohol preference additionally develop: (i) a preference for oral ingestion of morphine over water, resulting in morphine intake of 15 mg/kg/day; (ii) marked opioid dependence, as evidenced by the generation of strong withdrawal signs upon naloxone administration; (iii) prefrontal cortex alterations known to be associated with the loss of control over drug intake, namely, demyelination, axonal degeneration, and a reduction in glutamate transporter glt-1 levels; and (iv) glial striatal neuroinflammation and brain oxidative stress, as previously reported for chronic alcohol and chronic nicotine use. 2023-12-09 2023-12-17 rat
Luis Gerardo Balcazar-Ochoa, Rosa Ventura-Martínez, Guadalupe Esther Ángeles-López, Claudia Gómez-Acevedo, Omar Francisco Carrasco, Raúl Sampieri-Cabrera, Anahí Chavarría, Abimael González-Hernánde. Clavulanic Acid and its Potential Therapeutic Effects on the Central Nervous System. Archives of medical research. vol 55. issue 1. 2023-12-01. PMID:38039802. studies have revealed that clav can increase glt-1 expression in the nucleus accumbens (nacc), medial prefrontal cortex (pfc), and spinal cord of rodents, to affect glutamate and dopaminergic neurotransmission, and exert an anti-inflammatory effect by modulating the levels of the cytokines tnf-α and interleukin 10 (il-10). 2023-12-01 2023-12-10 Not clear
Xiao Hu, Hui-Ling Zhao, Nurhumar Kurban, Yu Qin, Xi Chen, Su-Ying Cui, Yong-He Zhan. Reduction of BDNF Levels and Biphasic Changes in Glutamate Release in the Prefrontal Cortex Correlate with Susceptibility to Chronic Stress-Induced Anhedonia. eNeuro. vol 10. issue 11. 2023-11-23. PMID:37989582. reduction of bdnf levels and biphasic changes in glutamate release in the prefrontal cortex correlate with susceptibility to chronic stress-induced anhedonia. 2023-11-23 2023-11-28 rat
Xiao Hu, Hui-Ling Zhao, Nurhumar Kurban, Yu Qin, Xi Chen, Su-Ying Cui, Yong-He Zhan. Reduction of BDNF Levels and Biphasic Changes in Glutamate Release in the Prefrontal Cortex Correlate with Susceptibility to Chronic Stress-Induced Anhedonia. eNeuro. vol 10. issue 11. 2023-11-23. PMID:37989582. the present study investigated effects of chronic mild stress (cms) for 14, 21, and 35 d on anhedonia-like behavior and glutamate synapses in the pfc. 2023-11-23 2023-11-28 rat
Xiao Hu, Hui-Ling Zhao, Nurhumar Kurban, Yu Qin, Xi Chen, Su-Ying Cui, Yong-He Zhan. Reduction of BDNF Levels and Biphasic Changes in Glutamate Release in the Prefrontal Cortex Correlate with Susceptibility to Chronic Stress-Induced Anhedonia. eNeuro. vol 10. issue 11. 2023-11-23. PMID:37989582. additionally, 14 d of cms increased prefrontal glutamate release, and 35 d of cms decreased glutamate release, in addition to reducing synaptic proteins and spine density in the pfc. 2023-11-23 2023-11-28 rat
Xiao Hu, Hui-Ling Zhao, Nurhumar Kurban, Yu Qin, Xi Chen, Su-Ying Cui, Yong-He Zhan. Reduction of BDNF Levels and Biphasic Changes in Glutamate Release in the Prefrontal Cortex Correlate with Susceptibility to Chronic Stress-Induced Anhedonia. eNeuro. vol 10. issue 11. 2023-11-23. PMID:37989582. our findings revealed a progressive reduction of synaptic plasticity and biphasic changes in glutamate release in the pfc during cms. 2023-11-23 2023-11-28 rat
Elaine Zhu, Dave Mathew, Hyun Jung Jee, Mengqi Sun, Weizhuo Liu, Qiaosheng Zhang, Jing Wan. AMPAkines have site-specific analgesic effects in the cortex. Molecular pain. 2023-11-03. PMID:37921508. prior research has shown that ampakines, a class of drugs that increase glutamate signaling, can enhance descending inhibition from the prefrontal cortex (pfc) and nucleus accumbens. 2023-11-03 2023-11-08 rat
Dibyadeep Datta, Isabella Perone, Yury M Morozov, Jon Arellano, Alvaro Duque, Pasko Rakic, Christopher H van Dyck, Amy F T Arnste. Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer vulnerability in Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). 2023-10-24. PMID:37874022. macaque data have already shown that susceptible neurons in dorsolateral prefrontal cortex express a "signature of flexibility" near glutamate synapses on spines, where camp-pka magnification of calcium signaling opens nearby potassium and hyperpolarization-activated cyclic nucleotide-gated channels to dynamically alter synapse strength. 2023-10-24 2023-11-08 monkey
Dibyadeep Datta, Isabella Perone, Yury M Morozov, Jon Arellano, Alvaro Duque, Pasko Rakic, Christopher H van Dyck, Amy F T Arnste. Localization of PDE4D, HCN1 channels, and mGluR3 in rhesus macaque entorhinal cortex may confer vulnerability in Alzheimer's disease. Cerebral cortex (New York, N.Y. : 1991). 2023-10-24. PMID:37874022. results showed a similar pattern to dorsolateral prefrontal cortex, with pde4d and mglur3 positioned to regulate internal calcium release near glutamate synapses, and hcn1 channels concentrated on spines. 2023-10-24 2023-11-08 monkey
Li-Xin Jiang, Geng-Di Huang, Yong-Lu Tian, Ri-Xu Cong, Xue Meng, Hua-Li Wang, Chen Zhang, Xin Y. Diminished activation of excitatory neurons in the prelimbic cortex leads to impaired working memory capacity in mice. BMC biology. vol 21. issue 1. 2023-08-11. PMID:37568146. immunofluorescence staining of the prefrontal cortex was performed to detect the number of fos-positive neurons, calmodulin-dependent protein kinase ii-positive neurons, and glutamate decarboxylase-positive neurons in the prelimbic cortex and infralimbic cortex. 2023-08-11 2023-08-16 mouse
Mandana Shekarchian, Maghsoud Peeri, Mohammad Ali Azarbayjan. Physical activity in a swimming pool attenuates memory impairment by reducing glutamate and inflammatory cytokines and increasing BDNF in the brain of mice with type 2 diabetes. Brain research bulletin. 2023-08-05. PMID:37543294. we also measured inflammatory cytokines (interleukin (il)-6, il-1β, and tumor-necrosis-factor (tnf)-α), an anti-inflammatory cytokine (il-10), and brain-derived-neurotrophic-factor (bdnf), and glutamate levels in the hippocampus or prefrontal cortex of mice. 2023-08-05 2023-08-14 mouse
Mandana Shekarchian, Maghsoud Peeri, Mohammad Ali Azarbayjan. Physical activity in a swimming pool attenuates memory impairment by reducing glutamate and inflammatory cytokines and increasing BDNF in the brain of mice with type 2 diabetes. Brain research bulletin. 2023-08-05. PMID:37543294. while higher physical activity was associated with reduced body weight, glucose, and insulin resistance, attenuated memory impairment, il-6, il-1β, tnf-α, and glutamate, and increased bdnf levels in the hippocampus and prefrontal cortex of diabetic mice. 2023-08-05 2023-08-14 mouse
Mandana Shekarchian, Maghsoud Peeri, Mohammad Ali Azarbayjan. Physical activity in a swimming pool attenuates memory impairment by reducing glutamate and inflammatory cytokines and increasing BDNF in the brain of mice with type 2 diabetes. Brain research bulletin. 2023-08-05. PMID:37543294. this study shows that swimming training can normalize body weight and glucose-insulin axis and reduce inflammation and glutamate in the hippocampus and enhance the neurotrophic system in both the hippocampus and prefrontal cortex of diabetic mice. 2023-08-05 2023-08-14 mouse
Jae Hyun Yoo, Young Woo Park, Dohyun Kim, HyunWook Park, Bumseok Jeon. Effects of Parental Verbal Abuse Experience on the Glutamate Response to Swear Words in the Ventromedial Prefrontal Cortex: A Functional 1H-magnetic Resonance Spectroscopy Study. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 21. issue 3. 2023-07-10. PMID:37424423. effects of parental verbal abuse experience on the glutamate response to swear words in the ventromedial prefrontal cortex: a functional 1h-magnetic resonance spectroscopy study. 2023-07-10 2023-08-14 Not clear
Lewis S Crawford, Emily P Mills, A Peek, Vaughan G Macefield, Kevin A Keay, Luke A Henderso. Function and biochemistry of the dorsolateral prefrontal cortex during placebo analgesia: how the certainty of prior experiences shapes endogenous pain relief. Cerebral cortex (New York, N.Y. : 1991). 2023-07-06. PMID:37415068. there was no significant difference in the concentration of gamma-aminobutyric acid, glutamate, myo-inositol, or n-acetylaspartate at the level of the right dorsolateral prefrontal cortex between placebo responders and nonresponders. 2023-07-06 2023-08-14 human
Lewis S Crawford, Emily P Mills, A Peek, Vaughan G Macefield, Kevin A Keay, Luke A Henderso. Function and biochemistry of the dorsolateral prefrontal cortex during placebo analgesia: how the certainty of prior experiences shapes endogenous pain relief. Cerebral cortex (New York, N.Y. : 1991). 2023-07-06. PMID:37415068. moreover, we found placebo-related activation within the right dorsolateral prefrontal cortex and altered functional magnetic resonance imaging coupling between the dorsolateral prefrontal cortex and the midbrain periaqueductal gray, which also correlated with dorsolateral prefrontal cortex glutamate. 2023-07-06 2023-08-14 human