Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Anastasia S Tsingotjido. Oxytocin: A Multi-Functional Biomolecule with Potential Actions in Dysfunctional Conditions; From Animal Studies and Beyond. Biomolecules. vol 12. issue 11. 2022-11-11. PMID:36358953. |
oxytocin is a hormone secreted from definite neuroendocrine neurons located in specific nuclei in the hypothalamus (mainly from paraventricular and supraoptic nuclei), and its main known function is the contraction of uterine and/or mammary gland cells responsible for parturition and breastfeeding. |
2022-11-11 |
2023-08-14 |
Not clear |
Yun Lei, Dan Wang, Yu Bai, Jayvon Nougaisse, Neal L Weintraub, Ming Guo, Xin-Yun L. Leptin enhances social motivation and reverses chronic unpredictable stress-induced social anhedonia during adolescence. Molecular psychiatry. 2022-09-22. PMID:36138127. |
further mechanistic exploration revealed that leptin stimulated oxytocin gene transcription in the paraventricular nucleus of the hypothalamus, while oxytocin receptor blockade abolished the leptin-induced enhancement of socially-induced cpp. |
2022-09-22 |
2023-08-14 |
mouse |
Songhui Hu, Yurong Wang, Xu Han, Min Dai, Yongxing Zhang, Yuanyuan Ma, Shijun Weng, Lei Xia. Activation of oxytocin receptors in mouse GABAergic amacrine cells modulates retinal dopaminergic signaling. BMC biology. vol 20. issue 1. 2022-09-20. PMID:36127701. |
oxytocin, secreted by oxytocin neurons in the hypothalamus, is an endogenous neuropeptide involved in modulating multiple sensory information processing pathways, and its roles in the brain have been associated with prosocial, maternal, and feeding-related behaviors. |
2022-09-20 |
2023-08-14 |
mouse |
Takashi Maruyama, Makiko Shimizu, Naofumi Ikeda, Kazuhiko Baba, Mitsuhiro Yoshimura, Yoichi Uet. Expression of oxytocin in hypothalamus and reduction of nociceptive stress following administration of Kamikihi-to in female rats. Frontiers in pharmacology. vol 13. 2022-09-16. PMID:36110514. |
expression of oxytocin in hypothalamus and reduction of nociceptive stress following administration of kamikihi-to in female rats. |
2022-09-16 |
2023-08-14 |
rat |
Lindsey R Hammerslag, Bree A Humburg, Samantha G Malone, Joshua S Beckmann, Kathryn E Saatman, Valery Grinevich, Michael T Bard. Peer-induced cocaine seeking in rats: Comparison to nonsocial stimuli and role of paraventricular hypothalamic oxytocin neurons. Addiction biology. vol 27. issue 5. 2022-08-24. PMID:36001434. |
in addition, to assess a potential mechanism, an oxytocin (ot) promoter-linked hm3dq dreadd was infused into the paraventricular nucleus of the hypothalamus to determine whether peer-induced cocaine seeking is decreased by activation of ot neurons. |
2022-08-24 |
2023-08-14 |
rat |
Donatella Marazziti, Phuoc-Tan Diep, Sue Carter, Manuel G Carbon. Oxytocin: An Old Hormone, A Novel Psychotropic Drug And Possible Use In Treating Psychiatric Disorders. Current medicinal chemistry. 2022-07-27. PMID:35894453. |
oxytocin is a nonapeptide synthesized in the paraventricular and supraoptic nuclei of the hypothalamus. |
2022-07-27 |
2023-08-14 |
Not clear |
Yuko Meajima, Shoko Yokota, Tomoyuki Ono, Zhiqian Yu, Megumi Yamachi, Shizu Hidema, Kenneth E Nollet, Katsuhiko Nishimori, Hiroaki Tomita, Hiroyuki Yaginuma, Kenju Shimomur. Identification of oxytocin expression in human and murine microglia. Progress in neuro-psychopharmacology & biological psychiatry. 2022-07-16. PMID:35842075. |
oxytocin is a neuropeptide synthesized in the hypothalamus. |
2022-07-16 |
2023-08-14 |
human |
Qian Xu, Kunping Zhuo, Xiaotian Zhang, Yaoxia Zhang, Jiaojiao Xue, Ming-Sheng Zho. Oxytocin-induced endothelial nitric oxide dependent vasorelaxation and ERK1/2-mediated vasoconstriction in the rat aorta. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 26. issue 4. 2022-06-29. PMID:35766003. |
oxytocin is a neuropeptide produced primarily in the hypothalamus and plays an important role in the regulation of mammalian birth and lactation. |
2022-06-29 |
2023-08-14 |
human |
Elena V Kozlova, Meri De Angelis, Maximillian E Denys, Anthony E Bishay, Luis Campoy, Karl-Werner Schramm, Margarita C Curras-Collaz. Thyroid Supplementation Reverses the Abnormal Social and Oxytocin Phenotype Produced by Developmental Exposure to PBDEs in a Sex-Dependent Manner. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554351. |
in this study, we show that developmental exposure (via dam gd0-pnd21) to the pbde mixture, de-71 (l-de-71; 0.1 mg/kg/d), reduces oxytocin immunofluorescence density in the paraventricular nucleus of the hypothalamus (pvn) that is critical for social recognition memory in male and female f1 offspring relative to veh/con (0 mg/kg/d). |
2022-05-13 |
2023-08-13 |
Not clear |
Jared Alvarez, Kaitlin E Carson, Kirsteen Brownin. Perinatal High Fat Diet Decreases Oxytocinergic Innervation to the Brainstem. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556115. |
oxytocin is the prototypical anti-stress peptide, and the paraventricular nucleus of the hypothalamus (pvn) provides descending inputs to the dorsal vagal complex (dvc) within the brainstem. |
2022-05-13 |
2023-08-13 |
Not clear |
Stefano Musardo, Alessandro Contestabile, Marit Knoop, Olivier Baud, Camilla Bellon. Oxytocin neurons mediate the effect of social isolation via the VTA circuits. eLife. vol 11. 2022-04-22. PMID:35451958. |
social isolation-dependent behavioral deficits and changes in neural activity and synaptic plasticity were reversed by chemogenetic inhibition of oxytocin neurons in the paraventricular nucleus (pvn) of the hypothalamus. |
2022-04-22 |
2023-08-13 |
mouse |
Benjamin Bueman. Oxytocin-releasing reward: a remedy for cerebral inflammaging? Current aging science. 2022-04-18. PMID:35431008. |
oxytocinergic neurons emerging from the hypothalamus release oxytocin from the pituitary gland to the blood by axonal discharge to regulate reproductive organs. |
2022-04-18 |
2023-08-13 |
Not clear |
Benjamin Bueman. Oxytocin-releasing reward: a remedy for cerebral inflammaging? Current aging science. 2022-04-18. PMID:35431008. |
however, at the same time, oxytocin is secreted into neighboring areas of the hypothalamus from the dendrites of these neurons. |
2022-04-18 |
2023-08-13 |
Not clear |
Yan Tang, Ron Stoo. The petting factor: Oxytocin and social touch. Neuron. vol 110. issue 6. 2022-03-17. PMID:35298915. |
(2022) uncovered a sensory pathway by which social touch can activate oxytocin neurons in the hypothalamus. |
2022-03-17 |
2023-08-13 |
mouse |
Takahiro Tsuji, Kazumi Furuhara, Maria Gerasimenko, Anna Shabalova, Stanislav M Cherepanov, Kana Minami, Haruhiro Higashida, Chiharu Tsuj. Oral Supplementation with L-Carnosine Attenuates Social Recognition Deficits in CD157KO Mice via Oxytocin Release. Nutrients. vol 14. issue 4. 2022-02-26. PMID:35215455. |
although the expression of oxytocin and oxytocin receptors in the hypothalamus was not altered by l-carnosine supplementation, the concentration of oxytocin in cerebrospinal fluid was increased in cd157ko mice by l-carnosine supplementation. |
2022-02-26 |
2023-08-13 |
mouse |
Seoyoung Yoon, Yong-Ku Ki. Possible oxytocin-related biomarkers in anxiety and mood disorders. Progress in neuro-psychopharmacology & biological psychiatry. 2022-02-12. PMID:35150782. |
oxytocin, a neuropeptide synthesized in the hypothalamus, affects human psychology and behaviors such as social and affiliative behaviors, fear and emotion processing, and stress regulation. |
2022-02-12 |
2023-08-13 |
human |
Soledad Bárez-López, Agnieszka Konopacka, Stephen J Cross, Mingkwan Greenwood, Marina Skarveli, David Murphy, Michael P Greenwoo. Transcriptional and post-transcriptional regulation of oxytocin and vasopressin gene expression by CREB3L1 and CAPRIN2. Neuroendocrinology. 2022-01-20. PMID:35051932. |
water homeostasis is achieved by secretion of peptide hormones arginine vasopressin (avp) and oxytocin (oxt) that are synthesised by separate populations of magnocellular neurones (mcns) in the hypothalamus. |
2022-01-20 |
2023-08-13 |
Not clear |
b' Elif \\xc3\\x87al\\xc4\\xb1\\xc5\\x9fkan, Munise Nur \\xc5\\x9eahin, Mahmut Alper G\\xc3\\xbclda\\xc4\\x9. Oxytocin and Oxytocin Receptor Gene Regulation in Williams Syndrome: A Systematic Review. The Yale journal of biology and medicine. vol 94. issue 4. 2021-12-31. PMID:34970101.' |
oxytocin (ot), a neuropeptide synthesized at the hypothalamus, plays an important role in cognition and behavior, and is thought to be affecting ws patients' attitudes at its different amounts. |
2021-12-31 |
2023-08-13 |
Not clear |
Michael P Reilly, M Nicole Kunkel, Lindsay M Thompson, Andrew Zentay, Connor D Weeks, David Crews, Lawrence K Cormack, Andrea C Gor. Effects of endocrine-disrupting chemicals on hypothalamic oxytocin and vasopressin systems. Journal of experimental zoology. Part A, Ecological and integrative physiology. vol 337. issue 1. 2021-12-11. PMID:34018699. |
in adult (~p90) brains, we counted immunolabeled oxytocin and vasopressin cell numbers in the paraventricular nucleus (pvn) and supraoptic nucleus (son) of the hypothalamus. |
2021-12-11 |
2023-08-13 |
rat |
Daniela Baptista-de-Souza, Lígia Renata Rodrigues Tavares, Lucas Canto-de-Souza, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souz. Behavioral, hormonal, and neural alterations induced by social contagion for pain in mice. Neuropharmacology. vol 203. 2021-12-03. PMID:34774550. |
to amplify the knowledge about behavioral, hormonal, and neural alterations induced by cohabitation with a pair in neuropathic pain, we investigated the effects of this protocol on (i) pain (writhing, formalin, hot plate tests) and depression (sucrose splash test) responses, (ii) the serum levels of corticosterone, testosterone, and oxytocin, (iii) noradrenalin, dopamine and its metabolite (dopac and hva) levels in the amygdaloid complex and insular cortex, (iv) neuronal activation pattern (fosb labeling) in the ventral tegmental area (vta), paraventricular nucleus of the hypothalamus (pvn) and supraoptic nucleus (so). |
2021-12-03 |
2023-08-13 |
mouse |