| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Torp, F M Haug, N Tønder, J Zimmer, O P Otterse. Neuroactive amino acids in organotypic slice cultures of the rat hippocampus: an immunocytochemical study of the distribution of GABA, glutamate, glutamine and taurine. Neuroscience. vol 46. issue 4. 1992-04-09. PMID:1347410. |
neuroactive amino acids in organotypic slice cultures of the rat hippocampus: an immunocytochemical study of the distribution of gaba, glutamate, glutamine and taurine. |
1992-04-09 |
2023-08-11 |
rat |
| C Rovira, Y Ben-Ar. Benzodiazepines do not potentiate GABA responses in neonatal hippocampal neurons. Neuroscience letters. vol 130. issue 2. 1992-04-08. PMID:1795875. |
benzodiazepines do not potentiate gaba responses in neonatal hippocampal neurons. |
1992-04-08 |
2023-08-11 |
Not clear |
| C Rovira, Y Ben-Ar. Benzodiazepines do not potentiate GABA responses in neonatal hippocampal neurons. Neuroscience letters. vol 130. issue 2. 1992-04-08. PMID:1795875. |
benzodiazepines (midazolam; flunitrazepam) and pentobarbital increase the response to exogenous gamma-aminobutyric acid (gaba) in adult hippocampal cells. |
1992-04-08 |
2023-08-11 |
Not clear |
| P Kugler, G Baie. Mitochondrial enzymes related to glutamate and GABA metabolism in the hippocampus of young and aged rats: a quantitative histochemical study. Neurochemical research. vol 17. issue 2. 1992-03-31. PMID:1347164. |
mitochondrial enzymes related to glutamate and gaba metabolism in the hippocampus of young and aged rats: a quantitative histochemical study. |
1992-03-31 |
2023-08-11 |
rat |
| P Kugler, G Baie. Mitochondrial enzymes related to glutamate and GABA metabolism in the hippocampus of young and aged rats: a quantitative histochemical study. Neurochemical research. vol 17. issue 2. 1992-03-31. PMID:1347164. |
quantitative histochemistry (scanning microphotometry) was used to determine the activities of the mitochondrial enzymes nad-linked isocitrate dehydrogenase (ec 1.1.1.41), l-glutamate dehydrogenase (ec 1.4.1.3) and gaba transaminase (ec 2.6.1.19) in various layers of the hippocampus (middle one third) of young (3-4 months old) and memory-impaired aged rats (28-30 months old). |
1992-03-31 |
2023-08-11 |
rat |
| P Kugler, G Baie. Mitochondrial enzymes related to glutamate and GABA metabolism in the hippocampus of young and aged rats: a quantitative histochemical study. Neurochemical research. vol 17. issue 2. 1992-03-31. PMID:1347164. |
however, the activities of the different enzymes (excepting gaba transaminase and cytochrome c oxidase) were significantly correlated in the hippocampus in both age groups. |
1992-03-31 |
2023-08-11 |
rat |
| P Kugler, G Baie. Mitochondrial enzymes related to glutamate and GABA metabolism in the hippocampus of young and aged rats: a quantitative histochemical study. Neurochemical research. vol 17. issue 2. 1992-03-31. PMID:1347164. |
age-dependent changes were only observed for nad-linked isocitrate dehydrogenase and gaba transaminase (significant increases of activities in some layers of the hippocampus, preferentially in the terminal field of the perforant path). |
1992-03-31 |
2023-08-11 |
rat |
| P Kugler, G Baie. Mitochondrial enzymes related to glutamate and GABA metabolism in the hippocampus of young and aged rats: a quantitative histochemical study. Neurochemical research. vol 17. issue 2. 1992-03-31. PMID:1347164. |
from the present study it is concluded that, 1. the enzymatic complement of mitochondria in neurons and glia depends upon layer specific metabolic processes of the hippocampus (also with respect to glutamatergic and gabaergic terminal fields) indicating a layer specific interaction of the enzymes studied to produce or catabolize glutamate and gaba, and 2. the age dependent changes of the studied enzymes are very restricted. |
1992-03-31 |
2023-08-11 |
rat |
| R L Jakab, C Lerant. Synaptology and origin of somatostatin fibers in the rat lateral septal area: convergent somatostatinergic and hippocampal inputs of somatospiny neurons. Brain research. vol 565. issue 1. 1992-02-28. PMID:1723020. |
the som innervation of somatospiny neurons which also receive hippocampal input and have been reported to contain gamma-aminobutyric acid (gaba) may be a morphological substrate of the som-related disinhibition in the lsa. |
1992-02-28 |
2023-08-11 |
rat |
| D Ruano, M Vizuete, J Cano, A Machado, J Vitoric. Heterogeneity in the allosteric interaction between the gamma-aminobutyric acid (GABA) binding site and three different benzodiazepine binding sites of the GABAA/benzodiazepine receptor complex in the rat nervous system. Journal of neurochemistry. vol 58. issue 2. 1992-02-13. PMID:1309562. |
these results seem to indicate that the different efficacy of gaba in enhancing the [3h]flunitrazepam binding could be due to the different bzd receptor subtypes present in the gabaa/bzd receptor complex and, moreover, led us to speculate that the low gaba efficacy found in membranes from spinal cord, hippocampus, and newborn cerebral cortex might be due to the presence in relatively high proportion of the very-low-affinity binding site for zolpidem. |
1992-02-13 |
2023-08-11 |
rat |
| P L Prather, S M Rezazadeh, J P Chen, H Lal, M W Marti. Modulation of benzodiazepine agonist and inverse-agonist receptor binding by GABA during ethanol withdrawal. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 6. 1992-02-13. PMID:1662404. |
therefore, results from the present study indicate that the capacity of gaba to modulate receptor affinity for benzodiazepine agonists and inverse-agonists in rat cortex, hippocampus or cerebellum is not altered during withdrawal from chronic ethanol. |
1992-02-13 |
2023-08-11 |
rat |
| H Hörtnagl, M L Berger, G Sperk, C Pif. Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus. Neuroscience. vol 45. issue 2. 1992-02-07. PMID:1684835. |
in these six hippocampal subregions the concentrations of noradrenaline, dopamine, serotonin, 3-methoxy-4-hydroxyphenylglycol, 5-hydroxyindoleacetic acid and the putative neurotransmitter amino acids glutamate, aspartate, gaba, glycine and taurine, and the levels of somatostatin and neuropeptide y and the activities of choline acetyltransferase, acetylcholinesterase and glutamate decarboxylase were measured. |
1992-02-07 |
2023-08-11 |
rat |
| B S McEwe. [Stress and hippocampus. An update on current knowledge]. Presse medicale (Paris, France : 1983). vol 20. issue 37. 1992-01-30. PMID:1836611. |
because of the positive results obtained with tianeptine on the hypophyseal-adrenal gland function and on the hippocampus, the authors are persuing further investigations to determine whether tianeptine can inhibit the loss of hippocampus nerve cells induced by repeated glucocorticoid administration or repeated stress and whether it potentializes the beneficial effects of glucocorticoids on the noradrenergic, serotonin and gaba benzodiazepin systems. |
1992-01-30 |
2023-08-11 |
rat |
| A Dresse, J Scuvée-Moreau, E Mocaaër, J C Poignan. [Contribution of electrophysiology to the study of tianeptine and other antidepressive agents]. Presse medicale (Paris, France : 1983). vol 20. issue 37. 1992-01-30. PMID:1836612. |
iontophoretic application of tianeptine does not affect the response of pyramidal cells in the hippocampus to application of serotonin or gamma amino-butyric acid (gaba), but lowers recovery time after iontophoretic administration of serotonin or gaba. |
1992-01-30 |
2023-08-11 |
Not clear |
| V V Trepakov, S A Saakia. [A pharmacological analysis of the GABA-ergic system of the primordial hippocampus in the frog Rana temporaria]. Nauchnye doklady vysshei shkoly. Biologicheskie nauki. issue 9. 1992-01-24. PMID:1661181. |
the data on evoked potentials (ep) in the frog primordial hippocampus during the surface application of gamma-aminobutyric acid (gaba), beta-alanine and aminooxyacetic acid in the region of ep recording are presented. |
1992-01-24 |
2023-08-11 |
Not clear |
| V V Trepakov, S A Saakia. [A pharmacological analysis of the GABA-ergic system of the primordial hippocampus in the frog Rana temporaria]. Nauchnye doklady vysshei shkoly. Biologicheskie nauki. issue 9. 1992-01-24. PMID:1661181. |
these results in the aggregate with the earlier described effects of picrotoxin, bicuculline, muscimol, baclofen (on ep) and gaba (on intracellular potentials) permit to suggest the presence of gaba-ergic inhibitory system and two types of gaba receptors in the frog primordial hippocampus. |
1992-01-24 |
2023-08-11 |
Not clear |
| T M Mishunina, V Ia Kononenk. [Formation of gamma-aminobutyric acid from glutamate and putrescine in rat hypothalamic and hippocampal synaptosomes and regulation of these processes by glucocorticoids]. Biokhimiia (Moscow, Russia). vol 56. issue 5. 1992-01-22. PMID:1684116. |
[formation of gamma-aminobutyric acid from glutamate and putrescine in rat hypothalamic and hippocampal synaptosomes and regulation of these processes by glucocorticoids]. |
1992-01-22 |
2023-08-11 |
rat |
| T M Mishunina, V Ia Kononenk. [Formation of gamma-aminobutyric acid from glutamate and putrescine in rat hypothalamic and hippocampal synaptosomes and regulation of these processes by glucocorticoids]. Biokhimiia (Moscow, Russia). vol 56. issue 5. 1992-01-22. PMID:1684116. |
gaba synthesis in synaptosomes of hippocampus from putrescine was increased by single hydrocortisone and multiple hormonal administrations. |
1992-01-22 |
2023-08-11 |
rat |
| R M Dawson, M Poretsk. The interaction of tacrine with benzodiazepine and GABA binding sites of guinea pig brain. Neuroscience letters. vol 129. issue 2. 1992-01-14. PMID:1660580. |
tacrine (1,2,3,4-tetrahydro-9-acridinamine) inhibited binding of [3h]flunitrazepam to benzodiazepine receptors of guinea pig hippocampus with an inhibition constant of 46 microm at 2 degrees c and 37 degrees c. gamma-aminobutyric acid (gaba) decreased the affinity of tacrine for the receptor, suggesting that tacrine may act as an inverse agonist. |
1992-01-14 |
2023-08-11 |
Not clear |
| F Zafra, E Castrén, H Thoenen, D Lindhol. Interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 22. 1991-12-26. PMID:1658793. |
interplay between glutamate and gamma-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. |
1991-12-26 |
2023-08-11 |
Not clear |