| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N A Lambert, W A Wilso. Discrimination of post- and presynaptic GABAB receptor-mediated responses by tetrahydroaminoacridine in area CA3 of the rat hippocampus. Journal of neurophysiology. vol 69. issue 2. 1993-04-28. PMID:8096243. |
the effects of the k+ channel blocker 9-amino-1,2,3,4-tetrahydroacridine (tha) on the actions of baclofen and gamma-aminobutyric acid (gaba) at post- and presynaptic gabab receptors were studied with whole-cell voltage-clamp recording in area ca3 of rat hippocampal slices. |
1993-04-28 |
2023-08-12 |
rat |
| J C Behrends, G ten Bruggencat. Cholinergic modulation of synaptic inhibition in the guinea pig hippocampus in vitro: excitation of GABAergic interneurons and inhibition of GABA-release. Journal of neurophysiology. vol 69. issue 2. 1993-04-28. PMID:8459290. |
the effect of cholinergic receptor activation on gamma-aminobutyric acid (gaba)-mediated inhibitory synaptic transmission was investigated in voltage-clamped ca1 pyramidal neurons (hpns) in the guinea pig hippocampal slice preparation. |
1993-04-28 |
2023-08-12 |
Not clear |
| D M Lovinger, S A Zimmerman, M Levitin, M V Jones, N L Harriso. Trichloroethanol potentiates synaptic transmission mediated by gamma-aminobutyric acidA receptors in hippocampal neurons. The Journal of pharmacology and experimental therapeutics. vol 264. issue 3. 1993-04-14. PMID:8383736. |
we have examined the actions of trichloroethanol (tcet), the active metabolite of the general anesthetic chloral hydrate, on responses mediated by gamma-aminobutyric acid (gaba)a receptors in response to application of exogenous gaba and activation of endogenous gabaergic transmission, by using hippocampal neurons in cell culture and in brain slices. |
1993-04-14 |
2023-08-12 |
Not clear |
| I Cloëz-Tayarani, C Harel-Dupas, G Fillio. Inhibition of [3H] gamma-aminobutyric acid release from guinea-pig hippocampal synaptosomes by serotonergic agents. Fundamental & clinical pharmacology. vol 6. issue 8-9. 1993-04-08. PMID:1292966. |
inhibition of [3h] gamma-aminobutyric acid release from guinea-pig hippocampal synaptosomes by serotonergic agents. |
1993-04-08 |
2023-08-11 |
Not clear |
| I Cloëz-Tayarani, C Harel-Dupas, G Fillio. Inhibition of [3H] gamma-aminobutyric acid release from guinea-pig hippocampal synaptosomes by serotonergic agents. Fundamental & clinical pharmacology. vol 6. issue 8-9. 1993-04-08. PMID:1292966. |
we studied the effects of (m-trifluoromethyl-phenyl)piperazine (tfmpp) and quipazine on the k(+)-evoked [3h]gaba release from guinea-pig hippocampal synaptosomes loaded with [3h]gaba.tfmpp and quipazine inhibited the k(+)-evoked release of [3h]gaba dose-dependently (ic50 = 153 and 123 microm, respectively). |
1993-04-08 |
2023-08-11 |
Not clear |
| I Cloëz-Tayarani, C Harel-Dupas, G Fillio. Inhibition of [3H] gamma-aminobutyric acid release from guinea-pig hippocampal synaptosomes by serotonergic agents. Fundamental & clinical pharmacology. vol 6. issue 8-9. 1993-04-08. PMID:1292966. |
our results show a serotonergic modulatory effect on the k(+)-evoked [3h]gaba release from guinea-pig hippocampal synaptosomes by receptors which are neither 5-ht1, 5-ht2 or 5-ht4. |
1993-04-08 |
2023-08-11 |
Not clear |
| N Nakata, H Kato, K Kogur. Effects of repeated cerebral ischemia on extracellular amino acid concentrations measured with intracerebral microdialysis in the gerbil hippocampus. Stroke. vol 24. issue 3. 1993-04-02. PMID:8446983. |
to clarify the role of elevated extracellular amino acid concentrations during ischemia on the cumulative neuronal damage after repeated cerebral ischemic insults, using a microdialysis technique we measured concentrations of the amino acids glutamate, glutamine, glycine, taurine, and gamma-aminobutyric acid in the gerbil hippocampus over three 2-minute forebrain ischemic insults induced at 1-hour intervals. |
1993-04-02 |
2023-08-12 |
Not clear |
| T Taira, M Uusi-Oukari, E R Korp. Early postnatal treatment with muscimol transiently alters brain GABAA receptors and open-field behavior in rat. European journal of pharmacology. vol 230. issue 3. 1993-04-01. PMID:8382616. |
maximal gaba stimulation of [3h]flunitrazepam binding was decreased in the cerebellum and hippocampus in m2 rats at the age of one month but not four months. |
1993-04-01 |
2023-08-12 |
rat |
| J S Isaacson, J M Solís, R A Nicol. Local and diffuse synaptic actions of GABA in the hippocampus. Neuron. vol 10. issue 2. 1993-03-26. PMID:7679913. |
local and diffuse synaptic actions of gaba in the hippocampus. |
1993-03-26 |
2023-08-12 |
Not clear |
| T Kubo, A Takano, N Tokushige, N Miyata, M Sato, S Hatakeyam. Electrical stimulation-evoked release of endogenous taurine from slices of the hippocampus, cerebral cortex and cerebellum of the rat. Journal of pharmacobio-dynamics. vol 15. issue 9. 1993-03-16. PMID:1287185. |
release of endogenous taurine by electrical stimulation of slices of the hippocampus, cerebral cortex, cerebellum and medulla oblongata of the rat was studied and compared with that of alanine and/or gamma-aminobutyric acid (gaba). |
1993-03-16 |
2023-08-11 |
rat |
| T Kubo, A Takano, N Tokushige, N Miyata, M Sato, S Hatakeyam. Electrical stimulation-evoked release of endogenous taurine from slices of the hippocampus, cerebral cortex and cerebellum of the rat. Journal of pharmacobio-dynamics. vol 15. issue 9. 1993-03-16. PMID:1287185. |
the stimulus-evoked release of taurine in the hippocampus was rapid in onset and declined to baseline fast, which was essentially similar to the time course pattern of the stimulus-evoked release of gaba. |
1993-03-16 |
2023-08-11 |
rat |
| S D Donevan, M A Rogawsk. GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses. Neuron. vol 10. issue 1. 1993-03-10. PMID:7678966. |
in whole-cell voltage-clamp recordings from cultured rat hippocampal neurons, the 2,3-benzodiazepine gyki 52466 was a potent antagonist of kainate- and ampa-activated currents (ic50 values, 7.5 and 11 microm, respectively), but was inactive against n-methyl-d-aspartate (nmda) or gamma-aminobutyric acid responses. |
1993-03-10 |
2023-08-12 |
rat |
| A Smolen, T N Smolen, P C Ha. Alterations in regional brain GABA concentration and turnover during pregnancy. Pharmacology, biochemistry, and behavior. vol 44. issue 1. 1993-03-09. PMID:8430130. |
gaba concentrations in the cerebellum, hippocampus, striatum, midbrain, and cortex from individual control, pregnant (days 17-18) and delivery-day heterogeneous stock mice were assayed using a fluorometric method. |
1993-03-09 |
2023-08-12 |
mouse |
| A Smolen, T N Smolen, P C Ha. Alterations in regional brain GABA concentration and turnover during pregnancy. Pharmacology, biochemistry, and behavior. vol 44. issue 1. 1993-03-09. PMID:8430130. |
at parturition, gaba concentrations in the cerebellum and cortex returned to control levels, but hippocampal, striatal, and midbrain gaba levels remained significantly depressed. |
1993-03-09 |
2023-08-12 |
mouse |
| A Smolen, T N Smolen, P C Ha. Alterations in regional brain GABA concentration and turnover during pregnancy. Pharmacology, biochemistry, and behavior. vol 44. issue 1. 1993-03-09. PMID:8430130. |
all the indices of gaba turnover--first-order rate constant, half-life, initial rate of synthesis, and turnover rate (product of first-order rate constant and initial concentration)--showed a significant reduction in pregnancy, which was continued through the time of delivery in all brain regions except the hippocampus. |
1993-03-09 |
2023-08-12 |
mouse |
| I Margaill, J M Miquet, A Doble, J C Blanchard, A Boirea. KATP channels modulate GABA release in hippocampal slices in the absence of glucose. Fundamental & clinical pharmacology. vol 6. issue 7. 1993-03-04. PMID:1490650. |
katp channels modulate gaba release in hippocampal slices in the absence of glucose. |
1993-03-04 |
2023-08-11 |
rat |
| I Margaill, J M Miquet, A Doble, J C Blanchard, A Boirea. KATP channels modulate GABA release in hippocampal slices in the absence of glucose. Fundamental & clinical pharmacology. vol 6. issue 7. 1993-03-04. PMID:1490650. |
we studied the effects of katp channel blockers on [3h]gaba release in the absence of glucose in rat hippocampal slices. |
1993-03-04 |
2023-08-11 |
rat |
| I Margaill, J M Miquet, A Doble, J C Blanchard, A Boirea. KATP channels modulate GABA release in hippocampal slices in the absence of glucose. Fundamental & clinical pharmacology. vol 6. issue 7. 1993-03-04. PMID:1490650. |
thus, in the absence of glucose, katp channel blockers enhance the release of gaba from rat hippocampal slices; this effect seems to be mediated by an overstimulation of non-nmda glutamate receptors. |
1993-03-04 |
2023-08-11 |
rat |
| G García-Ugalde, E Galarraga, J Bargas, S Brailowsk. Hyperexcitability of hippocampal CA1 region in brain slices after GABA withdrawal. Neuroscience letters. vol 147. issue 2. 1993-03-02. PMID:1337196. |
the interruption of gaba infusion in the cerebral cortex and in the hippocampus produces electrographic seizures in rats. |
1993-03-02 |
2023-08-11 |
rat |
| J Jolkkonen, M Mazurkiewicz, H Lahtinen, P Riekkine. Acute effects of gamma-vinyl GABA on the GABAergic system in rats as studied by microdialysis. European journal of pharmacology. vol 229. issue 2-3. 1993-03-02. PMID:1490526. |
gaba concentrations were monitored in the hippocampus by implantation of microdialysis probes. |
1993-03-02 |
2023-08-11 |
rat |